Dolutegravir M1 is a metabolite of the HIV integrase inhibitor dolutegravir .1It is formed primarily by the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1.
1.Zhu, J., Wang, P., Li, F., et al.CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV integrase inhibitorBiochem. Pharmacol.158174-184(2018)
CEF1, Influenza Matrix Protein M1 (58-66), is an epitope derived from the matrix protein of the influenza A virus. GILGFVFTL is an HLA-A2-restricted epitope from this matrix M1 protein.