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Anti-TMEM119 Antibody (7P728) 是一种 Mouse 抗体,靶向 TMEM119。Anti-TMEM119 Antibody (7P728) 可用于 WB。
Anti-TMEM119 Antibody (7P728) 是一种 Mouse 抗体,靶向 TMEM119。Anti-TMEM119 Antibody (7P728) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 880 | 5日内发货 | |
| 50 μL | ¥ 1,570 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-TMEM119 Antibody (7P728) is a Mouse antibody targeting TMEM119. Anti-TMEM119 Antibody (7P728) can be used in WB. |
| Ig Type | IgG3/Kappa |
| 克隆号 | 7P728 |
| 反应种属 | Mouse (predicted:Rat,Human) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cell membrane;Single-pass type I membrane protein;Cytoplasm;Endoplasmic reticulum membrane |
| 组织特异性 | Expressed in brain microglia (at protein level). Elevated expression levels seen in the brain of patients with Alzheimer disease. Expressed by osteoblast-like cells in bone tissues and follicular dendritic cells in lymphoid tissues. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Involved in positive regulation of bone mineralization; positive regulation of osteoblast differentiation; and positive regulation of osteoblast proliferation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| 免疫原 | KLH conjugated synthetic peptide: human TMEM119 |
| 抗原种属 | Human |
| 基因名称 | TMEM119 |
| 基因ID | |
| 蛋白名称 | Transmembrane protein 119 |
| 功能 | Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts (PubMed:20025746).May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity). |
| 分子量 | Theoretical: 29 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |