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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ADAM12 Polyclonal Antibody 2

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货号 TMAB-02279

Anti-ADAM12 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ADAM12。Anti-ADAM12 Polyclonal Antibody 2 可用于 WB,FCM。

Anti-ADAM12 Polyclonal Antibody 2

Anti-ADAM12 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-02279

Anti-ADAM12 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ADAM12。Anti-ADAM12 Polyclonal Antibody 2 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-ADAM12 Polyclonal Antibody 2 is a Rabbit antibody targeting ADAM12. Anti-ADAM12 Polyclonal Antibody 2 can be used in WB,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Rabbit)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cell membrane; Single-pass type I membrane protein.Isoform 2: Secreted.Isoform 3: Secreted (Potential).Isoform 4: Secreted (Potential).
组织特异性Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNF?(tumor necrosis factor ?, and modulation of the neurogenic function of Notch and Delta (1-3). ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail (1-3). ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone, and muscle, and catalyze proteolysis, adhesion, fusion, and intracellular signaling (3). ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), and is involved in egg-sperm fusion (4-6).
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADAM12
抗原种属
Human
基因名称
ADAM12
基因ID
8038
蛋白名称
Disintegrin and metalloproteinase domain-containing protein 12
Uniprot ID
O43184
功能
Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity).
化学信息
分子量Theoretical: 77/100 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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