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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-IGHM Monoclonal Antibody (2R959)

Synonyms: VH, MU, AGM1
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Anti-IGHM Monoclonal Antibody (2R959) 是一种 Mouse 抗体，靶向 IGHM。Anti-IGHM Monoclonal Antibody (2R959) 可用于 WB,IHC,FCM。

Anti-IGHM Monoclonal Antibody (2R959)

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Rating icon 还可以
货号 TMAT-0645

别名 VH, MU, AGM1

Anti-IGHM Monoclonal Antibody (2R959) 是一种 Mouse 抗体，靶向 IGHM。Anti-IGHM Monoclonal Antibody (2R959) 可用于 WB,IHC,FCM。

Anti-IGHM Monoclonal Antibody (2R959)
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产品介绍

生物活性
产品描述
Anti-IGHM Monoclonal Antibody (2R959) is a Mouse antibody targeting IGHM. Anti-IGHM Monoclonal Antibody (2R959) can be used in WB,IHC,FCM.
别名
VH, MU, AGM1
Ig Type
IgG1
克隆号
2R959
反应种属
Human
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910). The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD (see IGHD; MIM 1471770) on their surface. During an antibody response, activated B cells can switch to the expression of individual downstream heavy chain C region genes by a process of somatic recombination known as isotype switching. In addition, secreted Ig forms that act as antibodies can be produced by alternative RNA processing of the heavy chain C region sequences. Although the membrane forms of all Ig isotypes are monomeric, secreted IgM forms pentamers, and occasionally hexamers, in plasma (summary by Janeway et al., 2005).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human IGHM (AA: 310-452) expressed in E. Coli.
抗原种属
Human
基因名称
IGHM
基因ID
3507
蛋白名称
Immunoglobulin heavy constant mu
Uniprot ID
P01871
化学信息
分子量Theoretical: 49.3 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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