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Anti-PPM1A Monoclonal Antibody (4D555) 是一种 Mouse 抗体,靶向 PPM1A。Anti-PPM1A Monoclonal Antibody (4D555) 可用于 WB,FCM。
别名 PP2C-ALPHA, PP2Calpha, PP2CA
Anti-PPM1A Monoclonal Antibody (4D555) 是一种 Mouse 抗体,靶向 PPM1A。Anti-PPM1A Monoclonal Antibody (4D555) 可用于 WB,FCM。

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| 产品描述 | Anti-PPM1A Monoclonal Antibody (4D555) is a Mouse antibody targeting PPM1A. Anti-PPM1A Monoclonal Antibody (4D555) can be used in WB,FCM. |
| 别名 | PP2C-ALPHA, PP2Calpha, PP2CA |
| Ig Type | IgG1 |
| 克隆号 | 4D555 |
| 反应种属 | Human,Monkey |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human PPM1A (AA: 202-382) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | POU3F2 |
| 基因ID | |
| 蛋白名称 | POU domain, class 3, transcription factor 2 |
| Uniprot ID |
| 分子量 | Theoretical: 42.4 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |