Name: Anti-IL-13 Antibody (M1295)
Brand: TargetMol
SKU: T9901A-1296
Rating: 4.5 (1 reviews)

生物活性

产品描述	Anti-IL-13 Antibody (M1295) is a potent neutralizing antibody targeting human interleukin-13 (IL-13), acting by blocking the binding of IL-13 to its receptor complex. The compound is an essential tool for investigating Type 2 immune responses and the pathogenesis of bronchial asthma and atopic dermatitis, aiming to inhibit allergic inflammatory processes by downregulating IL-13-mediated signaling cascades.
靶点活性	IL-13:52 pM(Kd)
体外活性	在针对人 IL-13 的结合动力学实验中，Anti-IL-13 Antibody (M1295) 表现出 52 pM 的高亲和力（Kd），并抑制了 STAT6 磷酸化和 TF-1 细胞增殖 [1]。
别名	抗IL-13 抗体(M1295), M1295
克隆号	M1295
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P35225
靶点	IL-13

储存&溶解度

存储

Anti-IL-13 Antibody (M1295)