Tretoquinol l-form hydrochloride (Standard) is the standard substance of Tretoquinol l-form hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tretoquinol l-form hydrochloride is a β2-adrenergic receptor agonist used to treat asthma and chronic obstructive pulmonary disease.
Pamiparib, also known as BGB-290, is a highly potent and selective PARP inhibitor with favorable drug metabolism and pharmacokinetic properties. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of single-strand DNA breaks via the base-excision repair (BER) pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability, and eventually leads to apoptosis. BGB-290 may both potentiate the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.
Vanilmandelic acid, L-(+)- is a chemical intermediate in the synthesis of artificial vanilla flavorings and is an end-stage metabolite of the catecholamines, epinephrine, and norepinephrine. It is produced via intermediary metabolites.