Sulfo DBCO-PEG3-acid is a click chemistry reagent featuring an azide group. This compound is an analog of DBCO-acid, equipped with a PEG linker and a DBCO moiety. The DBCO group, known for its strain-promoted high-energy state, is commonly utilized in copper-free click reactions. The hydrophilic polyethylene glycol chain and the sulfonyl group enhance its water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (such as EDC or HATU) to form stable amide bonds. This reagent is for research use only and is of reagent grade.