t 2

Lysine-4,5-t2 is a bioactive chemical.

T2AA, a proliferating cell nuclear antigen (PCNA) inhibitor, disrupts protein-protein interactions between PCNA and both a PIP-box-containing peptide (IC50= 1 μM) and full-length p21, reducing cellular colocalization of PCNA with DNA polymerase δ. This compound effectively inhibits DNA replication and cell proliferation in U2OS and HeLa cells in a concentration-dependent manner, additionally inducing S phase cell cycle arrest at a 20 μM concentration. Furthermore, T2AA enhances DNA double strand break formation alongside cisplatin in a neutral comet assay and augments cisplatin-induced reductions in clonogenic survival in HeLa and U2OS cells.

Dextran T2 (MW 2,000) 是一种脱水葡萄糖聚合物，平均分子量2000，具有优异的生物降解性和生物相容性，常用于食品、药品、化妆品及研究领域。

RORγt agonist 2 是 RORγt 的有效的激动剂。RORγt agonist 2 能够诱导 Th17 细胞分化，增加促炎细胞因子水平，进而增强淋巴细胞的细胞毒性。RORγt agonist 2 对调节性 T 细胞的产生表现出抑制作用，能够抑制免疫反应。

RORγt Inverse agonist 2 is a selective, orally active inverse agonist of RORγt(EC50 of 119 nM).

T-2 Toxin (T-2 Mycotoxin) 是饲料和谷物中的各种镰刀菌种产生的真菌次生代谢产物，具有很强的生殖毒性，可诱发多种心血管毒性。T-2 Toxin 是一种抑制肽基转移酶 (60s ribosomal 亚基) 结合和蛋白质合成的抑制剂，通过ROS诱导的细胞凋亡诱导TM4细胞功能障碍，抑制 DNA 和 RNA 的合成，增加肝脏脂质过氧化物的水平。

T- 2 Tetraol is a T-2 toxin metabolite, and also a trichothecene mycotoxin, with less toxicity and is unable to induce apoptosis.

Voruciclib 是一种具有口服活性和选择性 CDK 抑制剂，Ki 为 0.626 nM-9.1 nM。它在多种弥漫性大 B 细胞淋巴瘤模型中抑制 MCL-1 的表达。它有效阻断 MCL-1 的转录调节子 CDK9。

Voruciclib hydrochloride is an orally active and selective inhibitor of CDK (Ki: 0.626 nM-9.1 nM).

T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) 是一种增殖细胞核抗原 (PCNA) 抑制剂，对 PCNA PIP-box 肽相互作用的 IC50 为 1 μM。 T2AA 通过停止 DNA 复制叉和抑制 PCNA 与 DNA 聚合酶 δ 的相互作用来引起 DNA 复制压力并抑制癌细胞生长。

Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.

Metofenazate difumarate is a selective calmodulin inhibitor.

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2 OH group open.

Boc-NH-PEG3 (PROTAC Linker 10) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 的合成分子。

T338C Src-IN-2 is a potent mutant inhibitor of c-Src T338C kinase(IC50 of 317 nM). T338C Src-IN-2 also inhibits T338C V323A and T338C V323S(IC50 of 57 nM 19 nM,respectively).

N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a polyethylene glycol (PEG)-based linker employed for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a polyethylene glycol (PEG) derivative specifically designed as a linker for PROTAC synthesis [1].

t-Boc-Aminooxy-PEG2-azide is a polyethylene glycol (PEG) derived linker compound employed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Azido-PEG2-t-butyl ester is a PEG derivative containing a t-butyl ester and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. Under acidic conditions, the t-butyl protected carboxyl group can be deprotected.

Thiol-PEG2-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

T-Type calcium channel inhibitor 2 (compound 6g) 是一种 T 型钙通道的有效抑制剂，能够作用于 Cav3.1 (α1G) (IC50: 31.0 μM)、Cav3.2 (α1H) (IC50: 83.1 μM)、Cav3.3 (α1I) (α1H) (IC50: 69.3 μM)。T-Type calcium channel inhibitor 2 对 A549、HCT-116 细胞表现出细胞毒性，IC50s 分别为5.0、6.4 μM。

t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66069，CAS号为 147489-06-3。

(2S,3S)-N-t-Boc-3-amino-1,2-epoxy-4-phenylbutane 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66307，CAS号为 98737-29-2。

Methanesulfonato(2-di-t-butylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T66570。