Anti-CD2 Antibody (1O658)

Name: Anti-CD2 Antibody (1O658)
Brand: TargetMol
SKU: TMAY-01420
Rating: 4.5 (1 reviews)

还可以

产品编号 TMAY-01420

别名 T11, SRBC, LFA-2, CD2 molecule

Anti-CD2 Antibody (1O658) 是一种 Mouse 抗体，靶向 CD2。Anti-CD2 Antibody (1O658) 可用于 IHC-P。

Anti-CD2 Antibody (1O658)

还可以

产品编号 TMAY-01420 别名 T11, SRBC, LFA-2, CD2 molecule

Anti-CD2 Antibody (1O658) 是一种 Mouse 抗体，靶向 CD2。Anti-CD2 Antibody (1O658) 可用于 IHC-P。

规格	价格	库存	数量
100 μL	¥ 1,679	5日内发货

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生物活性

产品描述	Anti-CD2 Antibody (1O658) is a Mouse antibody targeting CD2. Anti-CD2 Antibody (1O658) can be used in IHC-P.
别名	T11, SRBC, LFA-2, CD2 molecule
Ig Type	Monoclonal Mouse IgG1
克隆号	1O658
交叉反应	Human
验证活性	1. Immunochemical staining of human CD2 in human spleen with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CD2 in human lymph node with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human CD2 in human appendix with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用	IHC-P
推荐剂量	IHC-P: 1:100-1:500
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD2 (rh CD2; TMPY-01255; NP_001758.2; Met1-Asp209). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion molecule expressed on T cells and is recognized as a target for CD48 (rats) and CD58 (humans). CD2 has been shown to set quantitative thresholds in T cell activation both in vivo and in vitro. Further, intracellular CD2 signaling pathways and networks are being discovered by the identification of several cytosolic tail binding proteins. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain of CD2 is implicated in the signaling function. The complex of CD2 and CD58 also plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. As a cell surface glycoprotein, CD2 expressed on most human T cells and natural killer (NK) cells and plays an important role in mediating cell adhesion in both T-lymphocytes and in signal transduction.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human CD2 protein (TMPY-01255)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.