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Search Results for " mor "

317

抑制剂 & 化合物

58

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T77006	Felzartamab TJ-202,MOR-03087,MOR-202	CD38	Immunology/Inflammation
	Felzartamab(MOR-202) 是一种人源靶向 CD38 的单克隆抗体，可用于研究多发性骨髓瘤和晚期抗体介导的同种异体肾移植排斥反应。
T77125	Otilimab GSK 3196165,MOR103	CSF-1R	Tyrosine Kinase/Adaptors
	Otilimab (GSK 3196165) 是一种人源化抗粒细胞-巨噬细胞集落刺激因子 (GM-CSF) 单克隆抗体。Otilimab 具有抗炎活性，通过阻断 GM-CSF 与其细胞表面受体的相互作用来调节 GM-CSF 的生物学功能，可用于研究治疗重症 COVID-19 肺炎。
T77135	Tafasitamab MOR00208,XmAb5574,Tafasitamab-cxix	Apoptosis; Immunology/Inflammation related	Apoptosis; Immunology/Inflammation
	Tafasitamab (XmAb5574) 是一种 Fc 修饰的人源化单克隆抗体，靶向人 B 细胞表面抗原 CD19 ，可用于研究弥漫性大B细胞淋巴瘤。
T12151	N-Methylmoranoline MOR 14,N-Methyl-1-deoxynojirimycin,N-Methylmoranolin	Others	Others
	N-Methylmoranoline is an inhibitor of α-glucosidase.
T79547	MOR agonist-2	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	MOR agonist-2 (Compound 46) 为D3R拮抗剂及MOR激动剂，其Ki值分别为7.26 nM和564 nM。MOR agonist-2潜在以MOR部分激动机制实现镇痛效果，并通过D3R拮抗降低阿片类药物的滥用风险。
T79060	MOR agonist-1	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	MOR agonist-1为一种针对MOR（μ-opioid receptor）的激动剂，展现出优秀的镇痛效果，适用于疼痛及其相关疾病的研究应用。
T81763	MOR agonist-3
	MOR Agonist-3 (Compound 84) 是一种双重作用化合物，具有D3R/MOR拮抗活性（Ki值为55.2 nM和382 nM）。该化合物其MOR部分激动性质展现出镇痛潜力，并可能通通过D3R拮抗作用降低阿片类药物的滥用风险。MOR Agonist-3 亦适用于炎症治痈和神经性疼痛的研究领域。
T78778	D3R/MOR antagonist 1	Dopamine Receptor	GPCR/G Protein; Neuroscience
	D3R/MOR antagonist 1 (Compound 114) 为D3R/MOR拮抗剂，其对D3R和MOR的Ki值分别为46.5 nM和691 nM。该化合物通过MOR的部分激动作用可能具有镇痛效果，同时通过D3R的拮抗作用有助于降低阿片类药物的滥用风险。
T78779	D3R/MOR antagonist 2	Dopamine Receptor	GPCR/G Protein; Neuroscience
	D3R/MOR antagonist 2（Compound 121）为一种D3R/MOR拮抗剂，其Ki值分别为46.5 nM及691 nM。该化合物通过MOR部分激动作用可产生镇痛效果，并通过D3R拮抗减少阿片类药物的潜在滥用风险。
T7748	Dermorphin TFA 皮啡肽三氟乙酸盐	Others; Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience; Others
	Dermorphin TFA 是在两栖类皮肤中发现的天然七肽，是 μ-阿片受体激动剂，可用于抑制神经痛。
T7404	Dermorphin 皮啡肽	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Dermorphin 是在两栖类皮肤中发现的天然七肽，是 μ-阿片受体激动剂，可用于抑制神经痛。
T7218	Endomorphin 2 内吗啡肽 2	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Endomorphin 2 是一种高亲和力和选择性的 μ-阿片受体激动剂，对 kappa3 结合位点具有合理的亲和力，Ki 为 20 到 30 nM 之间。
TQ0178	Flumorph 氟吗啉,SYP-L190	Antifungal	Microbiology/Virology
	Flumorph (SYP-L190) 是一种羧酸酰胺杀菌剂。
T50045	(2R)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol; but-2-enedioic acid	Others	Others
	(2R)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol; but-2-enedioic acid 可用于多种化合物的合成。
T9046	Morpholinylmercaptobenzothiazole	Others	Others
	Morpholinylmercaptobenzothiazole 是一种后效快速硫化促进剂。
T19636	Morniflumate 马尼氟酯,Niflam,UP 164,UP-164,Morniflu,UP164	Others	Others
	Morniflumate (Niflam) 是一种非甾体抗炎药。它用于治疗炎症。
T40684	N-Nitrosomorpholine	Others	Others
	N-Nitrosomorpholine 是一种亚硝胺，具有光敏感性。它对动物有强致癌作用。
T10341	Antitumor agent-19	Others	Others
	Antitumor agent-19 是一种肿瘤相关巨噬细胞的调节剂，在 RAW 264.7 细胞和 BMDM 细胞中的 EC50 分别为 17.18 μM 和 18.87 μM。
T10319	Anamorelin RC-1291,阿拉莫林,ONO-7643	GHSR	GPCR/G Protein
	Anamorelin (ONO-7643) 是新型ghrelin receptor 激动剂，根据FLIPR 检测，得到其EC50=0.74 nM。
T1977	Dorsomorphin Compound C,BML-275	AMPK; Autophagy; TGF-beta/Smad	Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells
	Dorsomorphin (BML-275) 是一种 AMPK 抑制剂 (Ki=109 nM)，具有选择性和 ATP 竞争性。Dorsomorphin 可以抑制 BMP I 型受体 ALK2、ALK3 和 ALK6。Dorsomorphin 可诱导自噬，具有抗肿瘤活性。
TQ0267	Endomorphin 1 内吗啡肽 1,Endomorphin-1	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Endomorphin 1 是一种高亲和力和选择性的 μ-阿片受体激动剂，对 kappa3 结合位点具有合理的亲和力，Ki 为 20 到 30 nM 之间。
T7112	Ibutamoren Mesylate MK-0677,伊布莫仑甲磺酸盐,MK-677	GHSR	GPCR/G Protein
	Ibutamoren Mesylate (MK-0677) 是非肽段类生长激素促分泌素受体 (GHSR) 激动剂，也是一种口服有活性的生长激素 (GH) 促分泌素。
TQ0022	Capromorelin Tartrate 卡普瑞林酒石酸盐,CP 424391-18	GHSR	GPCR/G Protein
	Capromorelin Tartrate (CP 424391-18) 是口服有活性的 growth hormone secretagogue receptor 有效激动剂，能够作用于 hGHS-R1a(Ki:7 nM)。
T60194	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide	Histone Methyltransferase	Chromatin/Epigenetic
	N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide 是一种强效的、选择性的Enhancer of Zeste Homolog 2 (EZH2)，对EZH2 WT 和EZH2-Y641F 的IC50分别为37.6nM 和79.1nM。
T12096L	Morinidazole	Antibacterial	Microbiology/Virology
	Morinidazole 具有抗菌活性，可用于厌氧菌引起的阑尾炎、盆腔炎等细菌感染研究。
T11013L2	Levorotation nimorazole phosphate ester TFA	Others	Others
	Levorotation nimorazole phosphate ester TFA 是一种抗厌氧菌和抗原虫感染的试剂。
T9000	Pyrimorph	Antifungal	Microbiology/Virology
	Pyrimorph 是一种杀真菌剂，对 oomycetes 具有良好抑菌活性。
T5027	Dimemorfan phosphate 二甲啡烷磷酸盐,3,17-dimethylmorphinan	Sigma receptor	GPCR/G Protein
	Dimemorfan phosphate (3,17-dimethylmorphinan) 是 sigma 1 受体激动剂，用作强效镇咳药。
T7809L	Ipamorelin 2 Pivalic acid NNC-26-0161	Others	Others
	Ipamorelin 2 Pivalic acid (NNC-26-0161) 是一种生长激素释放肽，可诱导大鼠纵向骨生长。
T34281	Relamorelin BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131	GHSR	GPCR/G Protein
	Relamorelin (RM-131)是一种具有选择性和有效性的生长素释放肽/生长激素促分泌素受体 (GHSR) 激动剂，是一种有效的生长素释放肽模拟物，对 GHS-1a 受体具有很高的亲和力。Relamorelin 是一种具有中枢渗透性的五肽，可增加生长激素水平，加速胃排空，具有研究恶病质的潜力。
T0363	Morantel tartrate CP-12009-18 tartrate,UK 296418 tartrate,酒石酸甲噻嘧啶	Parasite	Microbiology/Virology
	Morantel tartrate (CP-12009-18 tartrate) 是一种主要用于牲畜的杀虫剂。
T0187	Amorolfine hydrochloride Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002	Antibiotic; Antifungal	Microbiology/Virology
	Amorolfine hydrochloride (Amorolfine HCl) 是一种抗真菌剂。
T13215	N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide N-(3-氯-4-吗啉代苯基)-N'-羟基甲脒,TS-011	Others	Others
	N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide (TS-011) 是一种选择性 20-羟基二十碳四烯酸合成抑制剂。
T60106	2,5-Morpholinedione, 4-methyl-6-(1-methylethyl)-3-(phenylmethyl)-	Others	Others
	2,5-Morpholinedione, 4-methyl-6-(1-methylethyl)-3-(phenylmethyl)- 是 Lateritin 的反式结构。
TP1251L	N-terminally acetylated Endomorphin-1 acetate Ac-L-Tyr-L-Pro-L-Trp-L-Phe-CONH2	Others	Others
	N-terminally acetylated Endomorphin-1 acetate (Ac-L-Tyr-L-Pro-L-Trp-L-Phe-CONH2) 是一种修饰的 Endomorphin-1。
T8415	4-Benzyl-2-carboxymorpholine hydrochloride	Others	Others
	4-Benzyl-2-carboxymorpholine hydrochloride 是一种用于蛋白质组学研究应用的专业产品，来自 Santa Cruz。
T0636	4-Methylmorpholine N-oxide	Others	Others
	4-Methylmorpholine N-oxide 常用作氧化反应中的共氧化剂和牺牲催化剂。
T60162	1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl]	Others	Others
	1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl]是一种抗纤维化的化合物。
T9132	Emorfazone 依莫法宗,PH011085	Others	Others
	Emorfazone (PH011085) 具有抗伤害作用。
T77687	3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one	Others	Others
	3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one 在人结肠癌细胞系中显示出抗肿瘤活性，可能用于防治血栓。
T10342	Antitumor agent-2	Others	Others
	Antitumor agent-2 具有抗炎和抗肿瘤活性，可用于研究癌症。
T0090	Moroxydine hydrochloride 盐酸吗啉胍,ABOB hydrochloride,病毒灵,Moroxydine HCl	Antiviral; Influenza Virus	Immunology/Inflammation; Microbiology/Virology
	Moroxydine hydrochloride (ABOB hydrochloride) 是一种合成的杂环双胍类抗病毒药物。它具有抗病毒活性，有助于预防和治疗流感。
T4469	Nemorubicin Methoxymorpholinyldoxorubicin,PNU-152243A,PNU 152243,奈莫柔比星	Others	Others
	Nemorubicin (PNU 152243) 是一种 Doxorubicin 衍生物，具有抗肿瘤活性。它需要完整的核苷酸切除修复系统才能发挥活性。它对多药耐药表型的多种肿瘤细胞系具有细胞毒性。
T2613	Almorexant 阿莫伦特,ACT 078573	OX Receptor	GPCR/G Protein; Neuroscience
	Almorexant (ACT 078573) 是一种有效的竞争性食欲素 1 受体 (OX1)/食欲素 2 受体 (OX2) 双重拮抗剂，OX1 和 OX2 的 Ki 值分别为 1.3 和 0.17 nM。
T21660L	b-Casomorphin (1-3) Acetate b-Casomorphin (1-3) Acetate (72122-59-9 Free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	b-Casomorphin (1-3) Acetate 是一种具有阿片样物质作用的三肽。
TP1404L	Hemorphin-7 acetate(152685-85-3 free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Hemorphin-7 acetate(152685-85-3 free base) 是一种 hemorphin 肽，一种源自血红蛋白 β 链的内源性阿片肽。 Hemorphin 肽具有镇痛和抗高血压活性，可激活阿片受体并抑制血管紧张素转换酶 (ACE)。
T23116	Oxotremorine sesquifumarate	AChR	Neuroscience
	Oxotremorine sesquifumarate 是一种毒蕈碱受体激动剂，对 M2 的激活作用更强，可用于神经学研究。
T17217	Vamorolone 地塞米松EP杂质E,VBP15	Glucocorticoid Receptor; NF-κB	Endocrinology/Hormones; NF-κB
	Vamorolone (VBP15) 是一种首创的，具有口服活性的解离性类固醇 (dissociative steroidal) 抗炎药和膜稳定剂。它抑制 (NF-κB) 抑制作用，并降低了激素的影响。它改善肌营养不良，无副作用。
T9311	4-[(E)-{[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazono}methy l]-2,6-dimethoxyphenol	Others	Others
	4-[(E)-{[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazono}methy l]-2,6-dimethoxyphenol 可用于化学和生命科学领域的研究。
T12339	Oxotremorine M iodide 碘化氧化震颤素M,Oxotremorine methiodide	AChR	Neuroscience
	Oxotremorine M iodide (Oxotremorine methiodide) 是 mAChR 的激动剂，可增强 NMDA 受体。

化合物

Cat.No: T77006

Synonym: TJ-202,MOR-03087,MOR-202

Target: CD38

Cat.No: T77125

Synonym: GSK 3196165,MOR103

Target: CSF-1R

Cat.No: T77135

Synonym: MOR00208,XmAb5574,Tafasitamab-cxix

Target: Apoptosis, Immunology/Inflammation related

N-Methylmoranoline

Cat.No: T12151

Synonym: MOR 14,N-Methyl-1-deoxynojirimycin,N-Methylmoranolin

Target: Others

MOR agonist-2

Cat.No: T79547

Target: Opioid Receptor

MOR agonist-1

Cat.No: T79060

Target: Opioid Receptor

MOR agonist-3

Cat.No: T81763

D3R/MOR antagonist 1

Cat.No: T78778

Target: Dopamine Receptor

D3R/MOR antagonist 2

Cat.No: T78779

Target: Dopamine Receptor

Cat.No: T7748

Synonym: 皮啡肽三氟乙酸盐

Target: Others, Opioid Receptor

Cat.No: T7404

Synonym: 皮啡肽

Target: Opioid Receptor

Cat.No: T7218

Synonym: 内吗啡肽 2

Target: Opioid Receptor

Cat.No: TQ0178

Synonym: 氟吗啉,SYP-L190

Target: Antifungal

(2R)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol; but-2-enedioic acid

Cat.No: T50045

Target: Others

Morpholinylmercaptobenzothiazole

Cat.No: T9046

Target: Others

Cat.No: T19636

Synonym: 马尼氟酯,Niflam,UP 164,UP-164,Morniflu,UP164

Target: Others

N-Nitrosomorpholine

Cat.No: T40684

Target: Others

Antitumor agent-19

Cat.No: T10341

Target: Others

Cat.No: T10319

Synonym: RC-1291,阿拉莫林,ONO-7643

Target: GHSR

Cat.No: T1977

Synonym: Compound C,BML-275

Target: AMPK, Autophagy, TGF-beta/Smad

Cat.No: TQ0267

Synonym: 内吗啡肽 1,Endomorphin-1

Target: Opioid Receptor

Ibutamoren Mesylate

Cat.No: T7112

Synonym: MK-0677,伊布莫仑甲磺酸盐,MK-677

Target: GHSR

Capromorelin Tartrate

Cat.No: TQ0022

Synonym: 卡普瑞林酒石酸盐,CP 424391-18

Target: GHSR

N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)-4-methyl-4′-morpholino-[1,1′-biphenyl]-3-carboxamide

Cat.No: T60194

Target: Histone Methyltransferase

Cat.No: T12096L

Target: Antibacterial

Levorotation nimorazole phosphate ester TFA

Cat.No: T11013L2

Target: Others

Cat.No: T9000

Target: Antifungal

Dimemorfan phosphate

Cat.No: T5027

Synonym: 二甲啡烷磷酸盐,3,17-dimethylmorphinan

Target: Sigma receptor

Ipamorelin 2 Pivalic acid

Cat.No: T7809L

Synonym: NNC-26-0161

Target: Others

Cat.No: T34281

Synonym: BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131

Target: GHSR

Morantel tartrate

Cat.No: T0363

Synonym: CP-12009-18 tartrate,UK 296418 tartrate,酒石酸甲噻嘧啶

Target: Parasite

Amorolfine hydrochloride

Cat.No: T0187

Synonym: Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002

Target: Antibiotic, Antifungal

N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide

Cat.No: T13215

Synonym: N-(3-氯-4-吗啉代苯基)-N'-羟基甲脒,TS-011

Target: Others

2,5-Morpholinedione, 4-methyl-6-(1-methylethyl)-3-(phenylmethyl)-

Cat.No: T60106

Target: Others

N-terminally acetylated Endomorphin-1 acetate

Cat.No: TP1251L

Synonym: Ac-L-Tyr-L-Pro-L-Trp-L-Phe-CONH2

Target: Others

4-Benzyl-2-carboxymorpholine hydrochloride

Cat.No: T8415

Target: Others

4-Methylmorpholine N-oxide

Cat.No: T0636

Target: Others

1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl]

Cat.No: T60162

Target: Others

Cat.No: T9132

Synonym: 依莫法宗,PH011085

Target: Others

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

Cat.No: T77687

Target: Others

Antitumor agent-2

Cat.No: T10342

Target: Others

Moroxydine hydrochloride

Cat.No: T0090

Synonym: 盐酸吗啉胍,ABOB hydrochloride,病毒灵,Moroxydine HCl

Target: Antiviral, Influenza Virus

Cat.No: T4469

Synonym: Methoxymorpholinyldoxorubicin,PNU-152243A,PNU 152243,奈莫柔比星

Target: Others

Cat.No: T2613

Synonym: 阿莫伦特,ACT 078573

Target: OX Receptor

b-Casomorphin (1-3) Acetate

Cat.No: T21660L

Synonym: b-Casomorphin (1-3) Acetate (72122-59-9 Free base)

Target: Opioid Receptor

Hemorphin-7 acetate(152685-85-3 free base)

Cat.No: TP1404L

Target: Opioid Receptor

Oxotremorine sesquifumarate

Cat.No: T23116

Target: AChR

Cat.No: T17217

Synonym: 地塞米松EP杂质E,VBP15

Target: Glucocorticoid Receptor, NF-κB

4-[(E)-{[4,6-Di(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazono}methy l]-2,6-dimethoxyphenol

Cat.No: T9311

Target: Others

Oxotremorine M iodide

Cat.No: T12339

Synonym: 碘化氧化震颤素M,Oxotremorine methiodide

Target: AChR

Cat. No.	Product Name	Target	Signaling Pathways
TN1949	Moracin C 桑辛素 C,5-(6-羟基-2-苯并呋喃基)-2-(3-甲基-2-丁烯基)-1,3-苯二醇	ROS; NO Synthase	Immunology/Inflammation
	Moracin C 是一种发现于Morus mesozygia、Morus alba var. multicaulis 中的天然化合物，是一种抗炎剂。Moracin C 可抑制细胞中的一氧化氮（NO）释放和LPS 激活的活性氧（ROS）。
TN1253	3-hydroxymorindone	Others	Others
	3-hydroxymorindone 是一种来自海巴戟 Morinda citrifolia 的天然产物。 3-hydroxymorindone 是一种色素。
T5S1607	Morusin Mulberrochromene,桑辛素	NF-κB; Antibacterial; STAT	JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Morusin (Mulberrochromene) 是从M. australis 分离的去乙烯基化黄酮，可抑制NF-κB 和STAT3的活性，具有抗菌、抗肿瘤、抗氧化等各种生物活性。
T2835	Morin 桑色素,Toxylon pomiferum,Aurantica,Calico Yellow,Al-Morin	Others	Others
	Morin (Calico Yellow) 是植物性黄酮类化合物，具有较弱的抗氧化活性，是用于铝物种形成的荧光螯合剂。
T3410	Momordin Ic 地肤子皂苷Ic,地肤子皂苷 Ic,Momordin 1c	Apoptosis; MAPK; PI3K	Apoptosis; MAPK; PI3K/Akt/mTOR signaling
	Momordin Ic (Momordin 1c) 是山茱萸的主要皂苷成分，通过氧化应激调控线粒体功能障碍诱导细胞凋亡，具有抗癌活性。
T3414	Morroniside 莫诺苷,奎宁树	Apoptosis; MMP; Pyroptosis	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用，可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
TN4583	Moringin	gp120/CD4; IL Receptor; BCL; GSK-3; TNF; Wnt/beta-catenin; Caspase; COX; Nrf2; PPAR; p53	Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Moringin 是一种异硫氰酸酯，由 Moringa oleifera 种子中存在的硫代葡萄糖苷前体 glucoMoringin 通过黑芥子酶介导水解获得。Moringin 具有抗炎和抗氧化特性。
TN1950	Moracin M	PDE	Metabolism
	Moracin M 是桑白皮中的一种酚类成分，有效的磷酸二酯酶 4 (PDE4) 抑制剂，对于 PDE4D2，PDE4B2，PDE5A1 和 PDE9A2 的 IC50 分别为 2.9 μM，4.5 μM，> 40 μM 和 > 100 μM。Moracin M 具有抗炎活性。
TN1112	Morellic acid	Others	Others
	Morellic acid 提取于 Garcinia Morella 中，具有抗血管生成作用。
TN4630	Nemoralisin	Others	Others
	Nemoralisin exhibits weak cytotoxicities (IC50>10 uM) against HepG2, AGS, MCF-7, and A-549 cancer cell lines.
TN4581	Moracin D	c-Myc; TNF; COX; Antifection	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
TN1942	Momordicoside F1 苦瓜皂苷 F1	Others	Others
	Momordicoside F1 may have antiproliferative activities against MCF-7, WiDr, HEp-2, and Doay human tumor cell lines.
T15355	Fumitremorgin C 烟曲霉毒素c,12α-Fumitremorgin C	BCRP; Antibacterial; Antibiotic; ABC	Membrane transporter/Ion channel; Microbiology/Virology
	Fumitremorgin C (12α-Fumitremorgin C) 是ABCG2/BRCP 的选择性抑制剂。
T79940	Moracin N	Glutathione Peroxidase	Metabolism
	Moracin N, 一种可从桑叶中分离的铁死亡抑制剂，通过抑制氧化应激以发挥神经保护作用。
TN6544	24-Hydroxymomordicine III
	24-Hydroxymomordicine III 可用于生命科学领域的相关研究，其产品编号为 TN6544。
TN5515	Morelloflavone
	Morelloflavone 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5515，CAS号为 16851-21-1。
TN4629	Nemoralisin C	Others	Others
	Nemoralisin C shows antiproliferative activity against HepG2, AGS, MCF-7, and A-549 cancer cell lines.
TN1583	Dihydromorin	TRP/TRPV Channel	Membrane transporter/Ion channel
	trans-Dihydromorin is an effective hypopigmenting agent in normal skin cells, hypopigmenting agents effective in melanoma system may not be effective on normal melanocytes, indicating that a non-tumor melanocyte system is more suitable for the screening o
TN6323	7α-O-Methylmorroniside
	7α-O-Methylmorroniside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6323，CAS号为 119943-45-2。
TN2500	1,5,15-Tri-O-methylmorindol	Others	Others
	1,5,15-Tri-O-methylmorindol has effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA.
TN6863	Momordin IIc
	Momordin IIc is a natural product.
TN3744	Cyclomorusin	NOS; AChR	Immunology/Inflammation; Neuroscience
	Cyclomorusin exhibits competitive inhibition toward monophenolase activity of mushroom tyrosinase, the IC50 value of 0.092 microM. It evokes the stimulation of superoxide anion generation in fMLP-stimulated rat neutrophils. Cyclomorusin , neocyclomorusin
TN1940	Momordicine I	Others	Others
	Momordicine I has anti-diabetic and antifeedant activities.
TN1945	Momordicoside K	Others	Others
	Momordicoside K has antidiabetic activity.
TN4631	Nemorensine	Others	Others
	Nemorensine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4631，CAS号为 50906-96-2。
T79937	Mortatarin F	Glucosidase	Metabolism
	Mortatarin F (Compound 1) 是一种具有戊烯基化类黄酮结构的葡萄糖苷酶抑制剂，其IC50值为8.7 μΜ。该化合物可从桑叶中提取，并应用于研究降低血糖效果。
T79938	Mortatarin G	Glucosidase	Metabolism
	Mortatarin G (compound 3)，一种桑叶中分离得到的异戊二烯化黄酮类化合物，显示出显著的α-葡萄糖苷酶抑制效果，其IC50值为20.4±1.4 μM。
TN4084	Fumitremorgin B	Antifection	Microbiology/Virology
	Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on the cell cycle progression of mouse tsFT210 cells in the M phase, with the MIC value of 26.1 mic
TN4312	Isomorellic acid	Others	Others
	Isomorellic acid is a cytotoxic caged xanthone.
TN1944	Momordicoside I aglycone	Others	Others
	Momordicoside I aglycone is a natural product
TN1943	Momordicoside G	Others	Others
	Momordicosides K and L, the main bitter taste triterpene glycosides in Bitter melon; and bitter melon has been reported to have hypoglycemic, anti atherogenic and anti HIV activities.
TN4585	Moronic acid	HIV Protease; Antifection; HSV	Microbiology/Virology; Proteases/Proteasome
	Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an...
TN4577	Momordicoside X	Others	Others
	Momordicoside X displays moderate insulin secretion activity.
TN1941	Momordicoside A	Others	Others
	Momordicoside A has the inhibition effect on PIP1B.
TN1331	7-O-Methyl morroniside 金银花,7-O-甲基莫诺甙	Others	Others
	7-O-Methyl morroniside is a natural product from Lonicera morrowii.
T75646	Moroidin
	Moroidin是一种双环八肽，隶属于荨麻疹科环肽科，有效抑制纯化的微管蛋白聚合，表现为微管蛋白聚合抑制剂。此外，Moroidin对包括A549人肺癌细胞在内的多种癌细胞显示出细胞毒性作用，能诱导细胞凋亡。
T6596	Morin monohydrate Aurantica,桑色素.桑黄素,Morin Hydrate	Others	Others
	Morin monohydrate（Aurantica）是一种植物源黄酮类天然产物，抗氧化作用较弱。Morin作为一种荧光螯合剂，可应用于铝物种的生成过程
TN6241	Momordicin IV
	Momordicin IV 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6241，CAS号为 894412-35-2。
TN4582	Moracin T	c-Myc; COX	Cell Cycle/Checkpoint; Immunology/Inflammation; Neuroscience
	Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell proliferation; moracin treatment furthermo
TN1330	7-O-Ethylmorroniside 7-乙氧基莫诺苷,7-O-ethyl-morroniside,7-氧乙基莫诺苷,金银花	Others	Others
	7-O-ethyl-morroniside is a natural product from Lonicera morrowii.
TN1951	Moracin O 桑辛素 O,桑辛素O	HIF	Angiogenesis; Chromatin/Epigenetic
	Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 μM. Moracin O exhibits potent in vitro inhibitory ac
TN1952	Moracin P 桑辛素 P,桑辛素P	Others; ROS; HIF	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; Others
	Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.
TN1953	Morusinol 桑根皮醇,桑树醇	ERK; MEK; Autophagy; Ras	Autophagy; GPCR/G Protein; MAPK
	Morusinol 是从桑树根皮中提取出的类黄酮。 Morusinol 具有抗血小板和抗癌活性，在体内抑制动脉血栓形成，通过诱导自噬、G2/M 细胞周期阻滞、抑制细胞侵袭和迁移以及靶向 Ras/MEK/ERK 通路发挥抗肿瘤活性。
T36954	Nemorosone
	Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem...
TN4580	Morachalcone A	Tyrosinase	Proteases/Proteasome
	Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 uM. Morachalcone A exhibits neuroprotective effects on HT22-immortalized hippocampal cells agai
T81761	Morusignin L
	Morusignin L为一种表现出抗骨质疏松症效应的化学物质。
TN4576	Momordicine II	Others	Others
	Momordicine II may have antidiabetic activity, it significantly stimulated insulin secretion. It also can deter oviposition by L. trifolii significantly.
TN3245	7-O-Methylmorroniside	TNF	Apoptosis
	7-O-Methylmorroniside exhibits anti-inflammatory activity.
TN6059	Demethoxyfumitremorgin C
	Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and ex
TN1939	Momor-cerebroside I	Others	Others
	Momor-cerebroside I is a natural product from Sesamum indicum L.
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天然产物

Cat.No: TN1949

Synonym: 桑辛素 C,5-(6-羟基-2-苯并呋喃基)-2-(3-甲基-2-丁烯基)-1,3-苯二醇

Target: ROS, NO Synthase

3-hydroxymorindone

Cat.No: TN1253

Target: Others

Cat.No: T5S1607

Synonym: Mulberrochromene,桑辛素

Target: NF-κB, Antibacterial, STAT

Cat.No: T2835

Synonym: 桑色素,Toxylon pomiferum,Aurantica,Calico Yellow,Al-Morin

Target: Others

Cat.No: T3410

Synonym: 地肤子皂苷Ic,地肤子皂苷 Ic,Momordin 1c

Target: Apoptosis, MAPK, PI3K

Cat.No: T3414

Synonym: 莫诺苷,奎宁树

Target: Apoptosis, MMP, Pyroptosis

Cat.No: TN4583

Target: gp120/CD4, IL Receptor, BCL, GSK-3, TNF, Wnt/beta-catenin, Caspase, COX, Nrf2, PPAR, p53

Cat.No: TN1950

Target: PDE

Morellic acid

Cat.No: TN1112

Target: Others

Cat.No: TN4630

Target: Others

Cat.No: TN4581

Target: c-Myc, TNF, COX, Antifection

Momordicoside F1

Cat.No: TN1942

Synonym: 苦瓜皂苷 F1

Target: Others

Fumitremorgin C

Cat.No: T15355

Synonym: 烟曲霉毒素c,12α-Fumitremorgin C

Target: BCRP, Antibacterial, Antibiotic, ABC

Cat.No: T79940

Target: Glutathione Peroxidase

24-Hydroxymomordicine III

Cat.No: TN6544

Morelloflavone

Cat.No: TN5515

Cat.No: TN4629

Target: Others

Cat.No: TN1583

Target: TRP/TRPV Channel

7α-O-Methylmorroniside

Cat.No: TN6323

1,5,15-Tri-O-methylmorindol

Cat.No: TN2500

Target: Others

Cat.No: TN6863

Cat.No: TN3744

Target: NOS, AChR

Cat.No: TN1940

Target: Others

Momordicoside K

Cat.No: TN1945

Target: Others

Cat.No: TN4631

Target: Others

Cat.No: T79937

Target: Glucosidase

Cat.No: T79938

Target: Glucosidase

Fumitremorgin B

Cat.No: TN4084

Target: Antifection

Isomorellic acid

Cat.No: TN4312

Target: Others

Momordicoside I aglycone

Cat.No: TN1944

Target: Others

Momordicoside G

Cat.No: TN1943

Target: Others

Cat.No: TN4585

Target: HIV Protease, Antifection, HSV

Momordicoside X

Cat.No: TN4577

Target: Others

Momordicoside A

Cat.No: TN1941

Target: Others

7-O-Methyl morroniside

Cat.No: TN1331

Synonym: 金银花,7-O-甲基莫诺甙

Target: Others

Cat.No: T75646

Morin monohydrate

Cat.No: T6596

Synonym: Aurantica,桑色素.桑黄素,Morin Hydrate

Target: Others

Cat.No: TN6241

Cat.No: TN4582

Target: c-Myc, COX

7-O-Ethylmorroniside

Cat.No: TN1330

Synonym: 7-乙氧基莫诺苷,7-O-ethyl-morroniside,7-氧乙基莫诺苷,金银花

Target: Others

Cat.No: TN1951

Synonym: 桑辛素 O,桑辛素O

Target: HIF

Cat.No: TN1952

Synonym: 桑辛素 P,桑辛素P

Target: Others, ROS, HIF

Cat.No: TN1953

Synonym: 桑根皮醇,桑树醇

Target: ERK, MEK, Autophagy, Ras

Cat.No: T36954

Morachalcone A

Cat.No: TN4580

Target: Tyrosinase

Cat.No: T81761

Cat.No: TN4576

Target: Others

7-O-Methylmorroniside

Cat.No: TN3245

Target: TNF

Demethoxyfumitremorgin C

Cat.No: TN6059

Momor-cerebroside I

Cat.No: TN1939

Target: Others

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