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  • 抑制剂&激动剂
    377
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    407
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    18
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    10
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    8
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    56
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    4
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  • Ginsenoside F2
    人参皂苷F2
    T391662025-49-4
    Ginsenoside F2 是 Ginsenoside Rb1 的代谢物,通过激活内在的凋亡途径和线粒体功能障碍来诱导乳腺的凋亡,对乳腺癌干细胞具有抗增殖活性。
    • ¥ 166
    In stock
    规格
    数量
  • Goshonoside F2
    T12394690851-25-5
    Goshonoside F2 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T123946,CAS号为 90851-25-5。
    • 待询
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  • Icariside F2
    淫羊藿次苷F2
    TMA1890115009-57-9
    Icariside F2 shows modest α-glucosidase inhibitory (4.60±1.74% to 11.97±3.30%) and antioxidant activities. It also displays potent NF-κB inhibitory effects, with the IC50 value of 16.25 ± 2.19 uM.
    • ¥ 19400
    10-14周
    规格
    数量
  • MC-1-F2
    T696592376894-10-7In house
    MC-1-F2 是一种 FOXC2 直接抑制剂,具有抗癌活性,抑制癌症干细胞 (CSC) 特性,降低去势抵抗性前列腺癌 (CRPC) 细胞系的侵袭能力。MC-1-F2 可用于研究前列腺癌。
    • ¥ 1820
    In stock
    规格
    数量
  • Glycoside L-F2
    T125221
    Glycoside L-F2 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125221。
    • 待询
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  • Labdane F2
    T2559289900-49-2
    Labdane F2 is an antagonist of thromboxane B2 and leukotriene B4 isolated from the Spanish herb Sideritis javalambrensis.
    • ¥ 10600
    待询
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  • cis-4-Br-2,5-F2-PCPA
    T60359
    cis-4-Br-2,5-F2-PCPA (S1024) 抑制 LSD1 和 LSD2,Ki 值分别为 94 nM 和 8.4 μM。癌症干细胞中 LSD1异常表达,cis-4-Br-2,5-F2-PCPA 能够通过增加 CCRF-CEM 细胞中二甲基化组蛋白 H3 的 K4 (H3K4) 水平,抑制 LSD1活性和癌细胞增殖。
    • ¥ 10600
    10-14周
    规格
    数量
  • 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
    15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
    T359441163135-96-3
    Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacological studies on 15-keto-17-phenyl trinor PGF2α ethyl amide have been reported.
    • 待估
    35日内发货
    规格
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  • ent-8-iso-15(S)-Prostaglandin F2α
    ent-8-iso-15(S)-Prostaglandin F2α
    T35990214748-66-0
    Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.
    • 待估
    35日内发货
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  • ent-Prostaglandin F2α
    ent-Prostaglandin F2α
    T3599254483-31-7
    ent-Prostaglandin F2α 是 PGF2α 的对映体,在尿液中可被发现。
    • 待估
    35日内发货
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  • 13,14-dihydro Prostaglandin F2α
    13,14-dihydro Prostaglandin F2α,13,14-dihydro PGF2α
    T3614627376-74-5
    13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 µg 100 g.[1]
    • 待估
    35日内发货
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  • 15(S)-15-methyl Prostaglandin F2α isopropyl ester
    15(S)-15-methyl Prostaglandin F2α isopropyl ester
    T36155157283-72-2
    15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor. 15(S)-15-methyl PGF2α isopropyl ester is a lipophilic analog of 15(S)-15-methyl PGF2α methyl ester, which may be hydrolyzed in vivo to the fully active free acid.
    • ¥ 498
    待询
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    数量
  • 15(S)-15-methyl Prostaglandin F2α methyl ester
    15(S)-15-methyl Prostaglandin F2α methyl ester
    T3615635700-21-1
    15(S)-15-methyl Prostaglandin F2α methyl ester 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T36156,CAS号为 35700-21-1。
    • 待估
    35日内发货
    规格
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  • 8-iso-13,14-dihydro-15-keto Prostaglandin F2α
    8-iso-13,14-dihydro-15-keto Prostaglandin F2α
    T36165191919-02-5
    8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans. 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into rabbits. Early in the infusion (within 10 minutes) 8-iso-13,14-dihydro-15-keto PGF2α was a significant component of the metabolite profile, which was comprised mostly of dinor 8-isoprostane metabolites. 8-iso-13,14-dihydro-15-keto PGF2α weakly inhibits the U-46619 or collagen-induced aggregation of human platelets, although a number of the E-series isoprostanes are much more potent in this assay.
    • 待估
    35日内发货
    规格
    数量
  • 8-iso-15-keto Prostaglandin F2α
    8-iso-15-keto Prostaglandin F2α
    T36166191919-01-4
    8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the infusion (within 1-2 minutes) 8-iso -15-keto PGF2α was a major component of the metabolite profile, which was comprised mostly of unmetabolized 8-iso PGF2α. 8-iso -15-keto PGF2α is a vasoconstrictor when tested on the rat isolated thoracic aorta, acting via the TP (thromboxane) receptor.
    • 待估
    35日内发货
    规格
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  • 8-iso-15-keto Prostaglandin F2β
    8-iso-15-keto Prostaglandin F2β
    T361671621482-36-7
    8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF2β moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8-iso PGE1, 8-iso PGE2, or 8-iso PGF2α. 8-iso-15-keto PGF2β is a potential metabolite of 8-iso PGF2β via the 15-hydroxy PG dehydrogenase pathway. There are no published reports on the formation or biological activity of 8-iso-15-keto PGF2β.
    • 待估
    35日内发货
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  • 11β-Prostaglandin F2α
    11β-Prostaglandin F2α
    T3645538432-87-0
    11β-Prostaglandin F2α 是一种由 AKR1C3 催化的生物活性代谢物,可刺激前列腺素 F 受体并诱导乳腺癌中的 slug 表达。11β-Prostaglandin F2α 也是存在于尿液中的内源代谢物。
    • ¥ 9430
    35日内发货
    规格
    数量
  • ent-8-iso Prostaglandin F2α
    ent-8-iso Prostaglandin F2α
    T36617159812-83-6
    ent-8-iso Prostaglandin F2α 是猪视网膜和脑微血管的强效血管收缩剂,EC50 值分别为 30.6 和 53.5 nM。
    • 待估
    35日内发货
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  • Prostaglandin F2β
    T366214510-16-1
    Prostaglandin F2β (PGF2β) is the 9β-hydroxy stereoisomer of PGF2α. It is much less active than PGF2α in antifertility and bronchoconstrictor activities. PGF2β exhibits bronchodilating activity in guinea pigs and cats and antagonizes the bronchoconstrictor activity of PGF2α.
    • ¥ 879
    待询
    规格
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  • 8-Isoprostaglandin F2α
    8-iso Prostaglandin F2α
    T3716427415-26-5
    8-Isoprostaglandin F2α 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T37164,CAS号为 27415-26-5。
    • ¥ 6890
    待询
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    数量
  • 8-iso Prostaglandin F2β
    8-iso Prostaglandin F2β
    T37165177020-26-7
    8-iso Prostaglandin F2β 可用于生命科学领域的相关研究。其产品编号为 T37165,CAS号为 177020-26-7。
    • 待估
    35日内发货
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  • 2,3-dinor-11β-Prostaglandin F2α
    2,3-dinor-11β-Prostaglandin F2α
    T37275240405-20-3
    2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α when measured using 's 11β-PGF2α EIA Kit . The excretion rate for 2,3-dinor-11β-PGF2α is approximately 200-250 ng/24 hours in a normal adult.
    • 待估
    35日内发货
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  • Prostaglandin F2α 1,11-lactone
    Prostaglandin F2α 1,11-lactone, PGF2α 1,11-lactone
    T3732662410-84-8
    Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) 是前列腺素 F2α 的脂溶性前药,可用于治疗青光眼的研究。 Prostaglandin F2α 1,11-lactone 作为抗生育剂具有活性,可大大降低血管活性。
    • 待估
    35日内发货
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  • Prostaglandin F2α 1,15-lactone
    Prostaglandin F2α 1,15-lactone
    T3732755314-49-3
    PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, whereas PGF2α is ineffective.
    • 待估
    35日内发货
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