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Anti-ZNF281 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZNF281。Anti-ZNF281 Polyclonal Antibody 可用于 WB。
Anti-ZNF281 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZNF281。Anti-ZNF281 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-ZNF281 Polyclonal Antibody is a Rabbit antibody targeting ZNF281. Anti-ZNF281 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Chicken,Pig,Cow,Horse,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR. |
| 免疫原 | KLH conjugated synthetic peptide: Human ZNF281 |
| 抗原种属 | Human |
| 基因名称 | ZNF281 |
| 基因ID | |
| 蛋白名称 | Zinc finger protein 281 |
| Uniprot ID | |
| 功能 | Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the G-rich box in the enhancer region of these genes. |
| 分子量 | Theoretical: 97 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |