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Anti-FGF23 Polyclonal Antibody

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货号 TMAB-05991

Anti-FGF23 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FGF23。Anti-FGF23 Polyclonal Antibody 可用于 WB。

Anti-FGF23 Polyclonal Antibody

Anti-FGF23 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05991

Anti-FGF23 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FGF23。Anti-FGF23 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-FGF23 Polyclonal Antibody is a Rabbit antibody targeting FGF23. Anti-FGF23 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Note=Secretion is dependent on O-glycosylation.
组织特异性Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse FGF23
抗原种属
Mouse
基因名称
FGF23
基因ID
蛋白名称
Fibroblast growth factor 23
功能
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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