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Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody
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产品编号 TMAC-01262
别名 Phospho-EIF2S1 (S52), p-EIF2S1 (Ser52), p-EIF2S1 (S52), IF2A_HUMAN, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, EIF2S1 (p-Ser52), EIF2S1 (p-S52), EIF2A, EIF2 alpha, EIF2, EIF 2alpha, EIF 2A, EIF 2 alpha, EIF 2
Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-EIF2S1 (Ser 52)。Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody 可用于 WB,IP,IF,IHC-P。
Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody
Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody
还可以产品编号 TMAC-01262 别名 Phospho-EIF2S1 (S52), p-EIF2S1 (Ser52), p-EIF2S1 (S52), IF2A_HUMAN, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, EIF2S1 (p-Ser52), EIF2S1 (p-S52), EIF2A, EIF2 alpha, EIF2, EIF 2alpha, EIF 2A, EIF 2 alpha, EIF 2
Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-EIF2S1 (Ser 52)。Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody 可用于 WB,IP,IF,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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| 产品描述 | Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF2S1 (Ser 52). Anti-Phospho-EIF2S1 (Ser 52) Polyclonal Antibody can be used in WB,IP,IF,IHC-P. |
| 别名 | Phospho-EIF2S1 (S52), p-EIF2S1 (Ser52), p-EIF2S1 (S52), IF2A_HUMAN, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, EIF2S1 (p-Ser52), EIF2S1 (p-S52), EIF2A, EIF2 alpha, EIF2, EIF 2alpha, EIF 2A, EIF 2 alpha, EIF 2 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of eIF2α phosphorylation in untreated (A, C) and lambda protein phosphatase treated (B, D) HEK293 whole cell lysates. Antibodies tested include p-eIF2α (Ser 52)(A, B) and eIF2α(C, D). 2. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing cytoplasmic staining. |
| 应用 | |
| 推荐剂量 | WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Immunogen affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2, eIF2 and eIF2 (eukaryotic translation initiation factor 2 , and , respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2 controls the rate of tRNA translation. When eIF2 is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2 is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | A short amino acid sequence containing phosphorylated Ser 52 of eIF2α of human origin |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 36 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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