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抑制剂&激动剂
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TargetMol产品目录中 "c2β"的结果
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TargetMol产品目录中 "

c2β

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  • 抑制剂&激动剂
    1293
    抑制剂&激动剂
  • 化合物库
    2
    化合物库
  • 重组蛋白
    437
    重组蛋白
  • 多肽产品
    50
    多肽产品
  • 抗体抑制剂
    22
    抗体抑制剂
  • 染料试剂
    12
    染料试剂
  • PROTAC
    320
    PROTAC
  • 天然产物
    119
    天然产物
  • 同位素
    34
    同位素
  • 检测抗体
    652
    检测抗体
  • 疾病造模
    2
    疾病造模
  • 分子与细胞研究
    36
    分子与细胞研究
  • 标准品
    20
    标准品
  • Antifolate C2
    AGF-154, AGF154, AGF 154
    T266361286279-90-0In house
    Antifolate C2 (AGF 154) 具有抗肿瘤活性,在人肿瘤细胞的生长抑制实验中测得IC为0.14nM。Antifolate C2 可用于研究癌症和自身免疫疾病。
    • ¥ 2350
    现货
    规格
    数量
  • Taselisib
    RG-7604, GDC-0032
    T19991282512-48-4
    Taselisib (GDC-0032) 是 PI3K 抑制剂,靶向作用于突变 PI3KCA。它能够抑制 PI3Kα (IC50:0.29 nM),PI3Kβ (IC50:0.91 nM) 和 PI3Kγ (IC50:0.97 nM)。
    • ¥ 247
    现货
    规格
    数量
    TargetMol | Citations 客户已引用
  • PIK-93
    PIK 93
    T2616593960-11-3
    PIK-93 是一种合成的PI4KIIIβ抑制剂,IC50值为 19 nM,同时可抑制PI3Kγ和PI3Kα的活性,IC50值分别为 16 nM 和 39 nM。
    • ¥ 273
    现货
    规格
    数量
  • Licorice glycoside C2
    甘草苷 C2
    T11848202657-55-4
    Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis.
    • ¥ 2660
    待询
    规格
    数量
  • Mito-apocynin (C2)
    T120481254044-41-1
    Mito-apocynin (C2) is an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, has antineuroinflammatory effects.
    • ¥ 497
    5日内发货
    规格
    数量
  • Dracoflavan C2
    T125451
    Dracoflavan C2 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125451。
    • 待询
    规格
    数量
  • Calystegine C2
    T125479
    Calystegine C2 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125479。
    • 待询
    规格
    数量
  • Surfactin C2
    T125603171039-18-2
    Surfactin C2 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125603,CAS号为 171039-18-2。
    • 待询
    规格
    数量
  • Ciwujianoside C2
    T126337114892-56-7
    Ciwujianoside C2 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126337,CAS号为 114892-56-7。
    • 待询
    规格
    数量
  • Pseudolaric Acid C2
    T1385182508-35-8
    Pseudolaric Acid C2 是一种从 Pseudolarix kaempferi 二萜酸,是大鼠口服和静脉注射后血浆、尿液、胆汁和粪便中 Pseudolaric acid B 的特异性代谢产物。
    • ¥ 619
    现货
    规格
    数量
  • Lipid C2
    T2036103003022-09-8
    Lipid C2 是一种可电离阳离子脂质,广泛用于形成用于体内递送mRNA的脂质纳米颗粒 (LNP)。含有 Lipid C2 并封装mRNA报告基因的LNP在小鼠中选择性集聚于肝脏和脾脏,而不在心脏、肺或肾脏中积累。携带编码Epstein-Barr病毒 (EBV) 蛋白潜伏膜蛋白 2 (LMP-2) 的mRNA的LNP,与抗程序性细胞死亡蛋白 1 (PD-1) 抗体联用,可缩小肿瘤体积,逆转T细胞耗竭,提高CT26小鼠EBV感染结肠癌模型中脾脏中CD3+CD8+中心T细胞和CD3+CD8+效应记忆T细胞的比例,并降低表达Pd-1的CD3+T细胞的比例。
    • 待询
    规格
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  • C2 Ceramide
    Ceramide 2
    T226443102-57-6
    A potent modulator of cell proliferation and differentiation.
    • ¥ 683
    现货
    规格
    数量
  • AMPK activator C2
    Compound-2, Compound 2, C2
    T237341428422-55-2
    AMPK activator C2 is an AMPK allosteric activator.
    • ¥ 10600
    6-8周
    规格
    数量
  • Licorice saponin C2
    Saponin C2, from licorice, Licoricesaponin C2
    T32747118525-49-8
    Licorice saponin C2 is an oleanane-type triterpene oligoglycoside extracted from the air-dried root of Glycyrrhiza uralensis.
    • 待询
    规格
    数量
  • Palmitic acid-1,2,3,4-13C4
    Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
    T35790287100-89-4
    Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellular proteins, promotes protein-vesicle interactions, and regulates various G protein-coupled receptor functions.1Red blood cell palmitic acid levels are increased in patients with metabolic syndrome compared to patients without metabolic syndrome and are also increased in the plasma of patients with type 2 diabetes compared to individuals without diabetes.3,4 1.Fatima, S., Hu, X., Gong, R.-H., et al.Palmitic acid is an intracellular signaling molecule involved in disease developmentCell. Mol. Life Sci.76(13)2547-2557(2019) 2.Santos, M.J., López-Jurado, M., Llopis, J., et al.Influence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patientsAnn. Nutr. Metab.39(1)52-62(1995) 3.Yi, L.-Z., He, J., Liang, Y.-Z., et al.Plasma fatty acid metabolic profiling and biomarkers of type 2 diabetes mellitus based on GC/MS and PLS-LDAFEBS Lett.580(30)6837-6845(2006) 4.Kabagambe, E.K., Tsai, M.Y., Hopkins, P.N., et al.Erythrocyte fatty acid composition and the metabolic syndrome: A National Heart, Lung, and Blood Institute GOLDN studyClin. Chem.54(1)154-162(2008)
    • ¥ 2170
    35日内发货
    规格
    数量
  • C2 L-threo Ceramide (d18:1/2:0)
    C2 L-threo Ceramide (d18:1/2:0)
    T35927143615-69-4
    C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.
    • ¥ 2417
    待询
    规格
    数量
  • C2 Ceramide (d14:1/2:0)
    C2 Ceramide (d14:1/2:0)
    T362302097561-20-9
    C2 Ceramide (d14:1/2:0) is a bioactive sphingolipid. Dietary administration of C2 ceramide (d14:1/2:0) (100 μM) induces lipotoxic cardiomyopathy via increasing diastolic and systolic diameter as well as reducing fractional shortening and the number of normal cardiac contractile events in Drosophila.
    • ¥ 7200
    待询
    规格
    数量
  • C2 Phytoceramide (t18:0/2:0)
    T36671
    C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 μM) in suspended polymorphonuclear cells. It increases COX-2 protein levels 15-fold through ERK signaling. It induces death of keratinocytes (20% viability) with an ED50 value of 30 μM, the same concentration at which 35% of cells in a TUNEL assay are apoptotic. C2 Phytoceramide also has antiproliferative effects in CHO cells, with greater than 80% cytotoxicity achieved at a concentration of 20 μM, and induces internucleosomal DNA fragmentation. In addition, it inhibits the activation of phospholipase D (PLD) mediated by muscarinic acetylcholine receptors in vitro.
    • ¥ 2008
    待询
    规格
    数量
  • C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)
    T38011261155-87-7
    C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 in MDCK cells. It also increases apical-to-basal transport of vinblastine in human intestinal C2BBe1 cells.
    • ¥ 5750
    待询
    规格
    数量
  • C2 3'-sulfo Galactosylceramide (d18:1/2:0)
    C2 3'-sulfo Galactosylceramide (d18:1/2:0)
    T38185252846-08-5
    C2 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. It has been used as an internal standard in the quantification of lysosulfatides in mouse brain tissue and plasma.
    • ¥ 12150
    待询
    规格
    数量
  • Procyanidin C2
    Procyanidine C2
    T8139737064-31-6
    Procyanidin C2,源自Fagopyrum dibotrys (D. Don) Hara,为酚苷类化合物。
    • ¥ 5500
    5日内发货
    规格
    数量
  • C2 L-erythro Ceramide (d18:1/2:0)
    N-acetyl-L-erythro-Sphingosine, L-erythro Ceramide (d18:1/2:0), L-erythro Cer(d18:1/2:0)
    T85188150338-90-2
    C2 L-erythro Ceramide (d18:1/2:0) 是一种脂质分子,可用于生命科学相关研究,其 CAS 号为 150338-90-2。
    • 待询
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  • C2 Sphingomyelin (d18:1/2:0)
    Sphingomyelin (d18:1/2:0), SM(d18:1/2:0), N-Acetyl Sphingosylphosphorylcholine, Acetyl Sphingomyelin
    T8527874713-54-5
    C2 Sphingomyelin (d18:1/2:0) 是一种脂质分子,可用于生命科学相关研究,其 CAS 号为 74713-54-5。
    • 待询
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  • FEN1-IN-4
    FEN1 Inhibitor C2
    T85451995893-58-7
    FEN1-IN-4 (FEN1 Inhibitor C2) 是人类皮瓣内切核酸酶-1 (hFEN1) 抑制剂。
    • ¥ 346
    现货
    规格
    数量