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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SHOC2 Polyclonal Antibody

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货号 TMAB-12778

Anti-SHOC2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SHOC2。Anti-SHOC2 Polyclonal Antibody 可用于 WB,ELISA,ICC/IF。

Anti-SHOC2 Polyclonal Antibody

Anti-SHOC2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12778

Anti-SHOC2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SHOC2。Anti-SHOC2 Polyclonal Antibody 可用于 WB,ELISA,ICC/IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍

生物活性
产品描述
Anti-SHOC2 Polyclonal Antibody is a Rabbit antibody targeting SHOC2. Anti-SHOC2 Polyclonal Antibody can be used in WB,ELISA,ICC/IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBELISAICC/IF
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000; ICC/IF: 1:50 - 1:100
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus upon growth factor stimulation.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SHOC2/Sur8
抗原种属
Human
基因名称
SHOC2
基因ID
8036
蛋白名称
Leucine-rich repeat protein SHOC-2
Uniprot ID
Q9UQ13
功能
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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