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Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CDC25B (Ser353)。Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody 可用于 WB。
Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CDC25B (Ser353)。Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDC25B (Ser353). Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody can be used in WB. |
别名 | p-CDC25B (Ser353), p-CDC25B (S353), CDC25B (p-Ser353), CDC25B (p-S353) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of extracts from COS7 cells treated with Etoposide using Phospho-CDC25B (Ser353) antibody TMAC-00761. The lane on the right is treated with the antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of serine 353(R-R-S(p)-V-T) derived from Human CDC25B |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 64 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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