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Search Results for " egfr "

Targets Recommended: EGFR VEGFR Apoptosis EGFR

592

抑制剂 & 化合物

29

天然产物

8

化合物库

3

TargetMol 试剂盒

86

重组蛋白

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Cat. No.	Product Name
L3400	临床期小分子药物库		3404 compounds
	3404 个临床期化合物集合，可用于高通量筛选和高内涵筛选；
L2193	抗肝癌化合物库		1787 compounds
	1787 种与肝癌相关的化合物，可以用于抗肝癌药物研发和药理研究；
L2192	抗胰腺癌化合物库		2238 compounds
	2238 种与胰腺癌相关的化合物，可以用于高通量和高内涵筛选；
L2194	抗结直肠癌化合物库		1545 compounds
	1545 种与结直肠癌相关的化合物，可以用于高通量和高内涵筛选；
L2191	抗乳腺癌化合物库		1939 compounds
	1939 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
L1610	FDA 上市激酶抑制剂库		263 compounds
	263种靶向激酶的上市药物集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L1600	激酶抑制剂库		2720 compounds
	2720 种激酶抑制剂/调节剂的独特集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L9410	共价抑制剂库		1920 compounds
	1920 种小分子的独特集合，包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子，如氯乙酰基，2-氯丙酰基，丙烯酰基，1-丙-2-炔基，1-丁-2-炔基，酮羰基，二硫键等，可以用于共价抑制剂药物研发；

化合物库

临床期小分子药物库

Cat.No: L3400

Compounds: 3404

抗肝癌化合物库

Cat.No: L2193

Compounds: 1787

抗胰腺癌化合物库

Cat.No: L2192

Compounds: 2238

抗结直肠癌化合物库

Cat.No: L2194

Compounds: 1545

抗乳腺癌化合物库

Cat.No: L2191

Compounds: 1939

FDA 上市激酶抑制剂库

Cat.No: L1610

Compounds: 263

激酶抑制剂库

Cat.No: L1600

Compounds: 2720

共价抑制剂库

Cat.No: L9410

Compounds: 1920

Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0058	EGFR inhibitor kit EGFR inhibitor kit
CL0068	VEGFR inhibitor kit VEGFR inhibitor kit
CL0085	HSP inhibitor kit HSP inhibitor kit

TargetMol 试剂盒

EGFR inhibitor kit

Cat.No: CL0058

VEGFR inhibitor kit

Cat.No: CL0068

HSP inhibitor kit

Cat.No: CL0085

Cat. No.	Product Name	Target	Signaling Pathways
T5168	EGFR-IN-12 EGFR Inhibitor	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-12 (EGFR Inhibitor) 是一种 4,6-二取代的嘧啶，可诱导细胞凋亡，具有抗肿瘤活性。它是ATP 竞争性，不可逆且高度选择性的EGFR 抑制剂，IC50为 21 nM。它对EGFR 的选择性高于 HER4 和 55种其他激酶。它还抑制突变型EGFRL858R 和EGFRL861Q，IC50分别为 63 nM 和 4 nM。
T21954	EGFR/ErbB-2/ErbB-4 inhibitor-2 EGFR/ErbB2 Inhibitor	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) 是EGFR 和ErbB 的抑制剂，对EGFR、ErbB2 和 ErbB4 的IC50分别为 0.017、0.08 和 1.91 μM。
T11163	EGFR-IN-9	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-9 是一种有效的 EGFR 激酶抑制剂，对于野生型 EGFR 激酶和双重突变型 EGFR 激酶 (L858R/T790M) 的 IC50 分别为 7 nM 和 28 nM。EGFR-IN-9 具有抗肿瘤活性。
T2705	Mutant EGFR inhibitor	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Mutant EGFR inhibitor 是选择性EGFR 突变体抑制剂，可抑制EGFRL858R、EGFRExon 19 deletion 和EGFRT790M。
T11162	EGFR-IN-8	EGFR; c-Met/HGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-8 是 EGFR 和 c-Met 的双重抑制剂。 EGFR-IN-8可用于靶向 EGFR TKI 耐药的 NSCLC 的研究。
T11158	EGFR-IN-11	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-11 是 EGFR-酪氨酸激酶的选择性抑制剂，可诱导细胞凋亡。 EGFR-IN-11 抑制三重突变体 EGFRL858R/T790M/C797S，IC50 为 18 nM，并在 G0/G1 时阻止细胞周期。
T10802	CHMFL-EGFR-202	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	CHMFL-EGFR-202 是一种有效、不可逆的表皮生长因子受体 (EGFR) 突变型激酶抑制剂，对耐药突变型 EGFR T790M 和 WT EGFR 激酶作用的 IC50 分别为 5.3 nM 和 8.3 nM。
T11157L	EGFR-IN-1 hydrochloride	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-1 hydrochloride 是 L858R/T790M 突变体 EGFR 的不可逆特异性抑制剂，选择性是野生型 EGFR 的 100 倍。 EGFR-IN-1 hydrochloride 在 H1975 细胞和突变体 HCC827 细胞中表现出有效的抗肿瘤和抗增殖活性，IC50 分别为 4 和 28 nM。
T11160	EGFR-IN-5	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-5 是 EGFR 的特异性抑制剂。 EGFR、EGFR(L858R)、EGFR(L858R/T790M) 和 EGFR(L858R/T790M/C797S) 的 IC50 分别为 10.4、1.1、34、7.2 nM。
T11161	EGFR-IN-7 TQB3804	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-7 (TQB3804) 是一种有效选择性的EGFR 激酶抑制剂，对 EGFR (WT) 和 EGFR (mutant C797S/T790M/L858R) 的IC50值分别为 7.92 和 0.218 nM，具有抗肿瘤活性。
T16162	Mutated EGFR-IN-1 Osimertinib analog,AZD9291中间体1	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Mutated EGFR-IN-1 (Osimertinib analog) 是用于突变 EGFR 抑制剂设计的有用中间体，例如 L858R EGFR、Exon19 缺失激活突变体和 T790M 抗性突变体。
T79888	EGFR-IN-87	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-87 为EGFR酪氨酸激酶抑制剂，针对A431细胞中EGFR_d746-750, EGFR_L858R/T790M 及 EGFR_WT 具有IC50值分别约为3.1 nM、1.3 nM和7.1 nM，适用于癌症疾病研究。
T63732	EGFR-IN-3	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-3 是一种 EGFR 抑制剂，具有潜在的抗肿瘤活性。EGFR-IN-3 抑制 EGFRwt-TK，诱导细胞凋亡 (apoptosis)，可使细胞在G2/M期阻滞。
TP1613	[pTyr5] EGFR (988-993) [pTyr5] EGFR 988-993
	[pTyr5] EGFR (988-993) is a compound obtained from the auto-phosphorylation site, Tyr992, located within the sequence of the epidermal growth factor receptor (EGFR 988-993). This compound is frequently found bound with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B).
TQ0255	Olafertinib CK-101,EGFR-IN-3,RX-518	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Olafertinib (RX-518) 是新型突变选择性、不可逆、可口服的EGFR 酪氨酸酶抑制剂，可克服 NSCLC 中 T790M 介导的耐药性。
T75120	EGFR-IN-76	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-76 是一种有有效的 EGFR 抑制剂。
T35901	EGFR-IN-99 JBJ-03-142-02	EGFR; HER	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-99 (JBJ-03-142-02) 是一种 EGFR 和 HER2 Exon 20 插入突变抑制剂，具有抗增殖活性，可用于研究非小细胞肺癌 (NSCLC) 。
T9905	Cetuximab Cetuximab (anti-EGFR),C225,西妥昔单抗	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Cetuximab (C225) 属于单克隆抗体，是一种人源表皮生长因子受体 (EGFR) 的抑制剂 (Kd=0.201 nM)。Cetuximab 具有抗肿瘤活性，可以抑制肿瘤细胞增殖，诱导细胞凋亡。
T40209	EGFR-IN-15
	EGFR-IN-15 (compound I-005) is a potent EGFR inhibitor, exhibiting an IC50 value of 4 nM. This compound holds potential for oncological research applications.
T79861	EGFR/ErbB-2 inhibitor-1	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR/ErbB-2 inhibitor-1 是一种选择性的 ErbB2/HER2 抑制剂，能有效地阻断ErbB2和HER2的信号传导。
T27247	EGFR-IN-542
	EGFR-IN-542 is a novel EGFR inhibitor. EGFR-IN-542 significantly reduces myocardial inflammation, fibrosis, apoptosis and dysfunction. It shows promise for use in the treatment of obesity-induced cardiac complications.
T11157	EGFR-IN-1	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-1, an orally active and irreversible selective inhibitor targeting L858R/T790M mutant EGFR, exhibits strong antiproliferative and antitumor activity, particularly against H1975 cells and first line mutant HCC827 cells. This compound potently inhibits Gefitinib-resistant EGFR L858R/T790M mutations with a 100-fold selectivity over the wild-type EGFR.
T41099	EGFR Protein Tyrosine Kinase Substrate
	EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate.
T11164	EGFR mutant-IN-1	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR mutant- in-1, A 5-methylpyrimidopyridone derivative are effective selective EGFRL858R/T790M/C797S mutant inhibitors with IC50 of 27.5 nM, which significantly weakened EGFRWT effect.
T11159	EGFR-IN-2	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-2 is a non-covalent, mutation-selective and irreversible second-generation EGFR inhibitor.
T69807	EGFR-IN-451
	EGFR-IN-451 is an EGFR inhibitor, attenuating Ang II-induced Kidney Fibrosis.
T8525	EGFR-IN-16 AG473	EGFR; FGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-16 (AG473) 是一种EGFR 抑制剂，对 EGFR 和 HER-2 的pIC50分别为4.85和4.74。
T12131	Mutated EGFR-IN-3	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Mutated EGFR-IN-3 is a ATP-competitive and highly selective allosteric dibenzodiazepinone EGFR(L858R/T790M) and EGFR(L858R/T790M/C797S) inhibitor(IC50 of 12 nM and 13 nM, respectively. )
T12130	Mutated EGFR-IN-2	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Mutated EGFR-IN-2 is an inhibitor of mutant-selective EGFR.
T73154	EGFR-IN-70
	EGFR-IN-70 是一种有效的EGFR 抑制剂，对于EGFRLR/TM/CS 和EGFRWT，其IC50值分别为 23.6 和 307.5 nM。EGFR-IN-70 具有抗增殖活性并抑制EGFR 的磷酸化。EGFR-IN-70 可用于癌症研究。
T62009	EGFR-IN-71
	EGFR-IN-71 是有效的表皮生长因子受体 (EGFR)抑制剂（IC50= 3.7 μM）。EGFR-IN-71 在脊索瘤中具有研究价值。
T73178	EGFR-IN-75
	EGFR-IN-75 是一种EGFRWT 和EGFRT790M 抑制剂，IC50值分别为 0.28 μM 和 5.02 μM。EGFR-IN-75 具有抗癌和抗氧化活性。
T78574	EGFR-IN-85	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-85（Compound 1）为EGFR抑制剂，对EGFRvⅢ磷酸化具有0.19 μM的IC50。本化合物可抑制肿瘤内EGFR信号传导，适用于恶性胶质瘤（GBM）研究。
T62457	EGFR-IN-54
	EGFR-IN-54 (Compound 3c) 是一种 EGFR 的有效抑制剂 (IC50: 1.623 μM)，对癌细胞具有毒性。
T63556	EGFR-IN-59
	EGFR-IN-59 是 EGFR 抑制剂，其IC50值为190 nM，也是一直凋亡 (apoptosis) 诱导剂。EGFR-IN-59 对非小肺癌细胞系 (A549) 和正常肺成纤维细胞 (WI38) 表现出细胞毒性的IC50分别为 8.62 和 52.6 μM。EGFR-IN-59 能够用于研究非小细胞肺癌 (NSCLC)、头颈癌、乳腺癌和结直肠癌等多种癌症。
T64255	EGFR-IN-48
	EGFR-IN-48 是一种有效的、口服具有活力的 EGFR 抑制剂，能够作用于 EGFRd19/TM/CS (IC50: 0.193 nM)、EGFRLR/TM/CS (IC50: 0.251 nM)、EGFRWT (IC50: 10.4 nM)。EGFR-IN-48 也能够抑制 BaF3EGFR del19/T790M/C797S 细胞 (IC50: 1.526 nM) 和 PC-9EGFR del19/T790M/C797S 细胞 (IC50: 66.7 nM)的增殖。
T79386	EGFR-IN-84	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-84 (Compound 6g)，作为EGFR抑制剂(IC50: 24 nM)，对A549细胞生长表现出抑制作用(IC50: 1.537 μM)，适用于肺癌研究。
T64020	EGFR-IN-17
	EGFR-IN-17 是有效的、选择性的表皮生长因子受体（EGFR）抑制剂，其 IC50 值为0.0002 μM，能够用于克服 C797S 介导的耐药性。
T61696	EGFR-IN-57
	EGFR-IN-57 (Compound 25a) 是一种有效的、具有口服活性的EGFR-TK 抑制剂，IC50值为 0.054 μM。EGFR-IN-57 也抑制VEGFR-2、CK2α、topoisomerase IIβ和tubulin polymerization，IC50值分别为 0.087、0.171、0.13 和 3.61 μM。EGFR-IN-57 诱导细胞 G2/M 和 pre-G1 期周期阻滞，诱导癌细胞凋亡 (apoptosis)。
T75261	EGFR-IN-1 TFA
	EGFR-IN-1 TFA 是一种口服活性不可逆的突变型选择性 L858R/T790MEGFR 抑制剂。与野生型 EGFR 相比，EGFR-IN-1 TFA 对 Gefitinib 耐药的 EGFRL858R/T790M 有 100 倍的抑制作用。EGFR-IN-1 TFA 对 H1975 细胞和 HCC827 细胞具有较强的抗增殖活性。具有抗肿瘤活性。
T76697	Panitumumab (anti-EGFR)
	Panitumumab (anti-EGFR) 是一种全人源IgG2抗EGFR 单克隆抗体，具有抗肿瘤活性。Panitumumab (anti-EGFR) 抑制肿瘤细胞增殖、存活和血管生成。Panitumumab (anti-EGFR) 可用于癌症研究，例如结肠癌。
T63996	EGFR-IN-50
	EGFR-IN-50 是一种针对 L858R 抗性突变的强效 EGFR 抑制剂，能够作用于 TEL-EGFR-L858R-BaF3 及 TEL-EGFR-T790M-L858R-BaF3，他们的 GI50 值分别为 8 nM、6.03 μM。EGFR-IN-50 对癌细胞表现出抗增殖作用。
T63774	EGFR-IN-58
	EGFR-IN-58 是一种有效的、选择性的、 ATP 竞争性的 EGFR 抑制剂。EGFR-IN-58 对黑色素瘤、结肠癌和血癌表现出显著的细胞毒性。
T74215	EGFR-IN-22
	EGFR-IN-22 是一种有效的 EGFR 抑制剂，对野生型 EGFR 和 EGFRL858R/T790M/C797S 的 IC50分别为 4.91 nM 和 0.54 nM。
T63178	EGFR-IN-39
	EGFR-IN-39 是一种丙烯酰胺衍生物，是一种 EGFR 的有效抑制剂。EGFR-IN-39 是一种低毒副作用的抗肿瘤药物。其中表皮生长因子受体 (EGFR) 的过度表达和突变已被明确证实会造成细胞生长无法控制，且与大多数癌症疾病（尤其是 NSCLC）的进展有关。EGFR-IN-33 具有潜力进行 EGFR 突变相关疾病的研究。
T63264	EGFR-IN-33
	EGFR-IN-33 是一种丙烯酰胺衍生物，是低毒副作用的抗肿瘤药物，是 EGFR 的有效抑制剂。其中表皮生长因子受体 (EGFR) 的过度表达和突变已被证实会导致细胞无节制的生长，并与大多数癌症疾病，尤其是 NSCLC 的进展有关。EGFR-IN-33 表现出 EGFR 突变相关疾病的研究潜力。
T63283	EGFR-IN-38
	EGFR-IN-38 是一种低毒副作用的、丙烯酰胺衍生物的抗肿瘤药物，是 EGFR 的有效抑制剂。其中表皮生长因子受体 (EGFR) 的过度表达和突变已被证实会导致细胞无节制的生长，并与大多数癌症疾病，尤其是 NSCLC 的进展有关。EGFR-IN-38 表现出 EGFR 突变相关疾病的研究潜力。
T62458	EGFR-IN-56
	EGFR-IN-56 (Compound 13a) 是一种 EGFR 的有效抑制剂，能够作用于 EGFRT790M (IC50: 541.7 nM) 和 EGFRT790M/L858R (IC50: 132.1 nM)。EGFR-IN-56 能够将癌细胞的细胞周期阻滞在 G2/M 期，并诱导细胞凋亡 (apoptosis)。
T78788	EGFR-IN-82	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-82（化合物8a）是一种口服活性的EGFR抑制剂，显示出对EGFRL858R/T790M/C797S的IC50为0.09 nM，以及对EGFRDel19/T790M/C797S的IC50为0.06 nM的高选择性，而对EGFRWT的抑制作用不明显。此化合物具备显著的抗增殖能力，并能有效抑制肿瘤增长，常用于非小细胞肺癌（NSCLC）的研究。
T63784	EGFR-IN-44
	EGFR-IN-44 是有效的、口服具有活力的 EGFRtyrosine kinase 抑制剂 (IC50: 4.11 nM)。EGFR-IN-44 口服生物利用度为33.57%，能够诱导细胞凋亡 (apoptosis)。EGFR-IN-44 能够用于研究非小细胞肺癌。

化合物

Cat.No: T5168

Synonym: EGFR Inhibitor

Target: Apoptosis, EGFR

EGFR/ErbB-2/ErbB-4 inhibitor-2

Cat.No: T21954

Synonym: EGFR/ErbB2 Inhibitor

Target: EGFR

Cat.No: T11163

Target: EGFR

Mutant EGFR inhibitor

Cat.No: T2705

Target: EGFR

Cat.No: T11162

Target: EGFR, c-Met/HGFR

Cat.No: T11158

Target: EGFR

CHMFL-EGFR-202

Cat.No: T10802

Target: EGFR

EGFR-IN-1 hydrochloride

Cat.No: T11157L

Target: EGFR

Cat.No: T11160

Target: EGFR

Cat.No: T11161

Synonym: TQB3804

Target: EGFR

Mutated EGFR-IN-1

Cat.No: T16162

Synonym: Osimertinib analog,AZD9291中间体1

Target: EGFR

Cat.No: T79888

Target: EGFR

Cat.No: T63732

Target: Apoptosis, EGFR

[pTyr5] EGFR (988-993)

Cat.No: TP1613

Synonym: [pTyr5] EGFR 988-993

Cat.No: TQ0255

Synonym: CK-101,EGFR-IN-3,RX-518

Target: EGFR

Cat.No: T75120

Target: EGFR

Cat.No: T35901

Synonym: JBJ-03-142-02

Target: EGFR, HER

Cat.No: T9905

Synonym: Cetuximab (anti-EGFR),C225,西妥昔单抗

Target: EGFR

Cat.No: T40209

EGFR/ErbB-2 inhibitor-1

Cat.No: T79861

Target: EGFR

Cat.No: T27247

Cat.No: T11157

Target: EGFR

EGFR Protein Tyrosine Kinase Substrate

Cat.No: T41099

EGFR mutant-IN-1

Cat.No: T11164

Target: EGFR

Cat.No: T11159

Target: EGFR

Cat.No: T69807

Cat.No: T8525

Synonym: AG473

Target: EGFR, FGFR

Mutated EGFR-IN-3

Cat.No: T12131

Target: EGFR

Mutated EGFR-IN-2

Cat.No: T12130

Target: EGFR

Cat.No: T73154

Cat.No: T62009

Cat.No: T73178

Cat.No: T78574

Target: EGFR

Cat.No: T62457

Cat.No: T63556

Cat.No: T64255

Cat.No: T79386

Target: EGFR

Cat.No: T64020

Cat.No: T61696

EGFR-IN-1 TFA

Cat.No: T75261

Panitumumab (anti-EGFR)

Cat.No: T76697

Cat.No: T63996

Cat.No: T63774

Cat.No: T74215

Cat.No: T63178

Cat.No: T63264

Cat.No: T63283

Cat.No: T62458

Cat.No: T78788

Target: EGFR

Cat.No: T63784

Cat. No.	Product Name	Target	Signaling Pathways
T1181	Gefitinib ZD1839,吉非替尼	EGFR; Tyrosine Kinases; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Gefitinib (ZD1839) 是一种 EGFR 一代抑制剂，具有口服活性，抑制 EGFR 19 Del 和 L858R 突变。Gefitinib 具有抗肿瘤活性，用于治疗 EGFR 突变的非小细胞肺癌。Gefitinib 用药会产生 EGFR C797S 耐药突变。
T3870	Cyasterone 杯苋甾酮,Cyasteron	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Cyasterone (Cyasteron) 是主要分离自金疮小草的一种天然 EGFR 抑制剂。它通过诱导细胞凋亡和细胞周期阻滞表现出抗增殖作用，可用于抗人类肿瘤的相关研究。
TL0016	Sulforaphene 油菜	Apoptosis; ERK; EGFR; NF-κB	Angiogenesis; Apoptosis; JAK/STAT signaling; MAPK; NF-κB; Tyrosine Kinase/Adaptors
	Sulforaphene 是从萝卜种子中分离出来的天然产物，对鹿茸幼苗的 ED50 约为 2 x 10 -4 M。它通过抑制 EGFR、p-ERK1/2、NF-κB 和其他信号促进癌细胞凋亡并抑制迁移。
T22974	Methyl 2,5-dihydroxycinnamate	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Methyl 2,5-dihydroxycinnamate 是 erbstatin 类似物，是一种高效、稳定的 EGF 受体相关酪氨酸激酶的抑制剂。
T1431	Khellin 凯林,Amicardine,Methafrone,Visammin	EGFR; Others	Angiogenesis; JAK/STAT signaling; Others; Tyrosine Kinase/Adaptors
	Khellin (Methafrone) 是从阿米芹中提取得到的一种呋喃并色酮，是EGFR 抑制剂，IC50为 0.15 µM。它体外具有抗增殖活性，还具有抗痉挛和冠状动脉舒张作用。
T2995	Chrysophanol 大黄酚,3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Chrysophanol (Turkey Rhubarb) 是掌叶大黄中的一种蒽醌类天然产物，可抑制EGF-诱导的EGFR 磷酸化，且抑制AKT 和mTOR/p70S6K 激活。
T1737	Genistein NPI 031L,三叶草,染料木素,金雀异黄酮	Apoptosis; EGFR; Endogenous Metabolite; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
	Genistein (NPI 031L) 是一种大豆异黄酮，是一种多重的酪氨酸激酶抑制剂，通过改变细胞凋亡，细胞周期和血管生成以及抑制转移对多种癌症有化疗作用。
T0683	Mevastatin Compactin,ML236B,美伐他汀	Apoptosis; Antibacterial; Antibiotic; HMG-CoA Reductase; Autophagy; Lipid	Apoptosis; Autophagy; Metabolism; Microbiology/Virology
	Mevastatin (ML236B) 是他汀类 HMG-CoA 还原酶抑制剂。它是一种降脂药，可诱导细胞凋亡，将癌细胞阻滞在 G0/G1期。它还可增加内皮型一氧化氮合酶的 mRNA 和蛋白质水平。它有抗肿瘤活性，用于心血管疾病的研究。
T6427	Butein 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因	Apoptosis; EGFR; Others; PDE; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Others; Tyrosine Kinase/Adaptors
	Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂，也是蛋白酪氨酸激酶抑制剂，还是一种SIRT1激活剂。它通过 AKT 和 ERK/p38 MAPK 通路，靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
T2851	Daphnetin 7,8-Dihydroxycoumarin,Daphnetol,瑞香素	EGFR; PKA; PKC; Parasite; Autophagy	Angiogenesis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Daphnetin (7,8-Dihydroxycoumarin) 是从 Genus Daphne 中分离得到的香豆素衍生物，有抗氧化、抗炎、抗疟疾和解热作用，可用于凝血功能障碍、类风湿性关节炎等疾病的相关研究。
TN1440	Beta-Hydroxyisovalerylshikonin	EGFR; Tyrosine Kinases; Prostaglandin Receptor; Src; AMPK; Fatty Acid Synthase	Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	Beta-hydroxyisovalerylshikonin 是分离自Lithospermium radix 的天然产物，具有抑制PTK 的作用，对 EGFR 和 v-Src 受体作用的IC50分别为 0.7 μM 和 1 μM。它对多种肿瘤细胞系均有抑制作用，可以高效诱导 NCI-H522 和 DMS114 细胞的死亡。
T4183	lavendustin A RG-14355,NSC 678027,薰草菌素	EGFR; Tyrosinase	Angiogenesis; JAK/STAT signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	lavendustin A (RG-14355) 是从链霉菌中分离得到的一种天然产物，是细胞渗透性表皮生长因子受体 (EGFR) 酪氨酸激酶抑制剂，能抑制血管内皮生长因子诱导的血管生成，阻断 LTPGABA-A 的诱导。
T4S0544	Furanodienone 呋喃二烯酮,莪术呋喃二烯酮	Apoptosis; HER	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Furanodienone 是来源于姜黄根茎的一种主要生物活性成分，可诱导细胞凋亡。
T2894	Norcantharidin Norcantharadine,去甲斑蝥素,Endothall anhydride	EGFR; c-Met/HGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Norcantharidin (Norcantharadine) 是一种合成的抗癌化合物，是人类结肠癌中 c-Met 和 EGFR 的双重抑制剂。
TN2309	Withanolide A	EGFR; TNF; NF-κB	Angiogenesis; Apoptosis; JAK/STAT signaling; NF-κB; Tyrosine Kinase/Adaptors
	Withanolide A 提取于印度草药 Ashwagandha 中，在严重受损的神经元中，能再生神经元突并重建突触。它延长了人类 EGFR 驱动的癌性秀丽隐杆线虫的寿命。
T5656	(±)-Norcantharidin Endothall anhydride,去甲斑蝥素,Norcantharidin	EGFR; c-Met/HGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	(±)-Norcantharidin (Endothall anhydride) 是一种人类结肠癌中 c-Met 和 EGFR 的双重抑制剂，可研究抗癌，具有抗血管生成活性。
TN5254	Wighteone Erythrinin B,6-Isopentenylgenistein	Antifungal	Microbiology/Virology
	Wighteone (Erythrinin B) 是一种从 Genista ephedroides 中提取出来的小分子化合物，具有潜在的抗真菌和抗癌活性，对 EGFR L858R/T790M 突变非小细胞肺癌具有抗肿瘤作用。。
TN1564	Delphinidin 3-glucoside chloride Delphinidin-3-O-glucoside chloride	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Delphinidin 3-glucoside chloride (Delphinidin-3-O-glucoside chloride) 是从 Hibiscus sabdariffa 提取物中发现的膳食酚类物质。Delphinidin 3-glucoside chloride 具有抗氧化活性，可诱导 B 细胞慢性淋巴细胞性白血病 (B CLL) 的促凋亡作用，抑制 EGFR，抑制血小板聚集。Delphinidin 3-glucoside chloride 具有抗肿瘤活性，通过调节 pAKT/IRF1/HOTAIR 通路发挥作用。
T36715	Tetrac Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Tetrac (Tetraiodothyroacetic acid)是L-甲状腺素(T4)的衍生物，是一种甲状腺整合素受体拮抗剂。Tetrac通过阻断EGFR介导的结直肠癌细胞信号传导来诱导抗增殖。Tetrac 可阻断 T4 和 3,5,3'-triiodo-L-thyronine (T3)在细胞表面甲状腺素整合素 αvβ3 受体上的作用。Tetra 具有抗血管生成、抗肿瘤活性和促凋亡活性。
TJS0339	Coumarin-3-carboxylic acid 香豆素-3-羧酸,3-Carboxycoumarin	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Coumarin-3-carboxylic acid (3-Carboxycoumarin) 是一种合成香豆素的重要起始化合物。其中香豆素是具有多种生物活性的天然产物。它的镧系复合物对 K-562 细胞具有抗增殖活性。
T2988	(-)-Epigallocatechin Gallate Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG	Ferroptosis; Reactive Oxygen Species; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	(-)-Epigallocatechin Gallate (EGCG) 是茶类黄酮，具有强大的抗氧化，抗炎和抗癌作用。它可抑制EGFR 信号传导，有抗癌作用。它是谷氨酸脱氢酶 1/2 抑制剂。它通过激活细胞色素c 氧化酶来诱导氧化磷酸化。
T2S0961	Chalcone benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone,查耳酮	EGFR; Antibacterial	Angiogenesis; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Chalcone (Cinnamophenone) 是从甘草中分离得到的一种芳香酮，可合成查耳酮衍生物。它具有多种生物和药理的活性，如抗炎、抗菌、抗癌、抗氧化、抗寄生虫等活性。
T13126	Tephrosin Deguelinol I,灰叶草素,Hydroxydeguelin	Others	Others
	Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.
T13559	Astragaloside VI	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway.
T2859	Biochanin A 4-Methylgenistein,鹰嘴豆芽素A,Olmelin	EGFR; FAAH; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
	Biochanin A (4-Methylgenistein) 是一种从红三叶车轴草中分离出来的异黄酮衍生物，具有抗癌特性。它是脂肪酸酰胺水解酶抑制剂，作用于小鼠、大鼠和人 FAAH，IC50分别为 1.8、1.4 和 2.4 μM。
TN3711	Corylifol C	ERK; EGFR; p38 MAPK; MEK	Angiogenesis; JAK/STAT signaling; MAPK; Tyrosine Kinase/Adaptors
	Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/ml, respectively).
TN2504	1,5-Dihydroxyxanthone	EGFR; AChR	Angiogenesis; JAK/STAT signaling; Neuroscience; Tyrosine Kinase/Adaptors
	1,5-Dihydroxyxanthone exhibits the epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitory activity, with the IC50 value of 90.34 nM. It may have anticholinesterase activity on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzym
TN5100	Taspine	ERK; EGFR; BCL; VEGFR; MAPK; Akt	Angiogenesis; Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibi
TN3525	Boehmenan	ERK; Phosphatase; EGFR; PARP; MEK; Wnt/beta-catenin; Akt; Caspase; STAT; p53	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
	(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell

天然产物

Cat.No: T1181

Synonym: ZD1839,吉非替尼

Target: EGFR, Tyrosine Kinases, Autophagy

Cat.No: T3870

Synonym: 杯苋甾酮,Cyasteron

Target: Apoptosis, EGFR

Cat.No: TL0016

Synonym: 油菜

Target: Apoptosis, ERK, EGFR, NF-κB

Methyl 2,5-dihydroxycinnamate

Cat.No: T22974

Target: EGFR

Cat.No: T1431

Synonym: 凯林,Amicardine,Methafrone,Visammin

Target: EGFR, Others

Cat.No: T2995

Synonym: 大黄酚,3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb

Target: EGFR

Cat.No: T1737

Synonym: NPI 031L,三叶草,染料木素,金雀异黄酮

Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy

Cat.No: T0683

Synonym: Compactin,ML236B,美伐他汀

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Cat.No: T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因

Target: Apoptosis, EGFR, Others, PDE, Autophagy

Cat.No: T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol,瑞香素

Target: EGFR, PKA, PKC, Parasite, Autophagy

Beta-Hydroxyisovalerylshikonin

Cat.No: TN1440

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Cat.No: T4183

Synonym: RG-14355,NSC 678027,薰草菌素

Target: EGFR, Tyrosinase

Cat.No: T4S0544

Synonym: 呋喃二烯酮,莪术呋喃二烯酮

Target: Apoptosis, HER

Cat.No: T2894

Synonym: Norcantharadine,去甲斑蝥素,Endothall anhydride

Target: EGFR, c-Met/HGFR

Cat.No: TN2309

Target: EGFR, TNF, NF-κB

(±)-Norcantharidin

Cat.No: T5656

Synonym: Endothall anhydride,去甲斑蝥素,Norcantharidin

Target: EGFR, c-Met/HGFR

Cat.No: TN5254

Synonym: Erythrinin B,6-Isopentenylgenistein

Target: Antifungal

Delphinidin 3-glucoside chloride

Cat.No: TN1564

Synonym: Delphinidin-3-O-glucoside chloride

Target: Apoptosis, EGFR

Cat.No: T36715

Synonym: Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid

Target: Apoptosis, EGFR

Coumarin-3-carboxylic acid

Cat.No: TJS0339

Synonym: 香豆素-3-羧酸,3-Carboxycoumarin

Target: VEGFR

(-)-Epigallocatechin Gallate

Cat.No: T2988

Synonym: Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

Cat.No: T2S0961

Synonym: benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone,查耳酮

Target: EGFR, Antibacterial

Cat.No: T13126

Synonym: Deguelinol I,灰叶草素,Hydroxydeguelin

Target: Others

Astragaloside VI

Cat.No: T13559

Target: EGFR

Cat.No: T2859

Synonym: 4-Methylgenistein,鹰嘴豆芽素A,Olmelin

Target: EGFR, FAAH, Autophagy

Cat.No: TN3711

Target: ERK, EGFR, p38 MAPK, MEK

1,5-Dihydroxyxanthone

Cat.No: TN2504

Target: EGFR, AChR

Cat.No: TN5100

Target: ERK, EGFR, BCL, VEGFR, MAPK, Akt

Cat.No: TN3525

Target: ERK, Phosphatase, EGFR, PARP, MEK, Wnt/beta-catenin, Akt, Caspase, STAT, p53

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00742	EGFR Protein, Human, Recombinant (His) mENA,NISBD2,ERBB1,HER1,PIG61,ERBB,epidermal growth factor re...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-04818	EGFR Protein, Cynomolgus, Recombinant (His) epidermal growth factor receptor	Cynomolgus	HEK293 Cells
	EGFR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.1 kDa and the accession number is A0A2K5WK39.
TMPY-02676	EGFR Protein, Mouse, Recombinant (His) Errp,AI552599,Errb1,9030024J15Rik,wa2,Erbb,wa-2,Wa5,epiderma...	Mouse	HEK293 Cells
	EGFR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.8 kDa and the accession number is Q01279.
TMPK-00426	EGFR Protein, Human, Recombinant (His & Avi) PIG61,mENA,NISBD2,EC 2.7.10.1,HER1,EC 2.7.10,ERBB1,LEGFR...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPK-00902	EGFR Protein, Rhesus macaque, Recombinant (His) HER1,EC 2.7.10,EGFR,NISBD2,ErbB,PIG61,ERBB1,LEG...	Rhesus	HEK293 Cells
	EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.8 kDa and the accession number is P55245.
TMPJ-00648	EGFR vIII Protein, Human, Recombinant (His) EGFR,Proto-oncogene c-ErbB-1,Epidermal growth facto...	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 61-75 Kda and the accession number is NP_001333870.
TMPK-00425	EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled EC 2.7.10.1,HER1,EGFR,PIG61,LEGFR,ErbB,ERB...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPJ-00647	EGFR vIII Protein, Human, Recombinant (hFc) EGFR,Epidermal growth factor receptor,Proto-oncogen...	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is NP_001333870.
TMPK-00427	EGFR Protein, Human, Recombinant (His & Avi), Biotinylated PIG61,ERBB,LEGFR,mENA,EC 2.7.10.1,EGFR,EC ...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.5 kDa and the accession number is P00533-1.
TMPJ-00646	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated Epidermal growth factor receptor,EGFR,Proto-oncogen...	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is NP_001333870.
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) epidermal growth factor receptor,PIG61,ERBB1,NISBD2,ERBB,HER...	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1.
TMPK-01073	CLEC14A Protein, Human, Recombinant (His) C14orf27,Epidermal growth factor receptor 5,UNQ236,EGFR<...	Human	HEK293 Cells
	CLEC14A is a single-pass transmembrane glycoprotein belonging to the vascular expressed C-type lectin family. CLEC14A is found to be expressed in vascular endothelial cells during embryogenesis and is also implicated in tumor angiogenesis.
TMPY-01043	EGFR Protein, Human, Recombinant (hFc) ERBB,mENA,HER1,ERBB1,PIG61,NISBD2,epidermal growth factor re...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95 kDa and the accession number is P00533-1.
TMPK-00691	EGFRVIII Protein, Human, Recombinant (His & Avi) EGFR,ErbB,mENA,HER1,LEGFR,EC 2.7.10.1,PIG6...	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi) is expressed in HEK2...
TMPY-02958	EGFR Protein, Rat, Recombinant (His) epidermal growth factor receptor	Rat	HEK293 Cells
	EGFR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.7 kDa and the accession number is E7CXR8.
TMPY-02675	EGFR Protein, Mouse, Recombinant (hFc) Erbb,AI552599,wa-2,9030024J15Rik,Errp,wa2,Errb1,Wa5,epiderma...	Mouse	HEK293 Cells
	EGFR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96 kDa and the accession number is Q01279.
TMPY-03724	EGFR Protein, Canine, Recombinant (His) epidermal growth factor receptor	Canine	Baculovirus Insect Cells
	EGFR Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is XP_533073.3.
TMPY-06524	EGFR Protein, Feline, Recombinant (His) epidermal growth factor receptor	Feline	Baculovirus Insect Cells
	EGFR Protein, Feline, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 70.18 kDa and the accession number is A0A337S424.
TMPY-00128	EGFR Protein, Rhesus, Recombinant (hFc) epidermal growth factor receptor	Rhesus	HEK293 Cells
	EGFR Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is XP_001107305.1.
TMPK-00689	EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled EC 2.7.10.1,EC 2.7.10,ERBB1,EGFR,mENA,NISBD2,HER1,E...	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled is expre...
TMPK-00690	EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled LEGFR,ERBB1,EGFR,HER1,PIG61,NISBD2,EC 2.7....	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled is exp...
TMPK-00692	EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated EC 2.7.10.1,PIG61,NISBD2,HER1,mENA,LEGFR,ErbB,EC 2....	Human	HEK293 Cells
	The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated is exp...
TMPY-05258	EGFR Protein, Human, Recombinant (Isoform Viii, hFc) NISBD2,epidermal growth factor receptor,ERBB,PIG61,mENA,ERBB...	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (Isoform Viii, hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession number is NP_001333870.1.
TMPY-06593	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated PIG61,ERBB1,ERBB,NISBD2,epidermal growth factor receptor,HER...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.90 kDa and the accession number is NP_001333870.1.
TMPY-05211	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His) NISBD2,PIG61,ERBB,mENA,epidermal growth factor receptor,HER1...	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is NP_001333870.1.
TMPY-05612	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated mENA,PIG61,HER1,ERBB1,ERBB,NISBD2,epidermal growth factor re...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.9 kDa and the accession number is P00533-1.
TMPY-06549	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His) ERBB,epidermal growth factor receptor,HER1,mENA,ERBB1,PIG61,...	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.09 kDa and the accession number is NP_001333870.1.
TMPY-05637	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated epidermal growth factor receptor,HER1,mENA,ERBB1,ERBB,NISBD2...	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 41.8 kDa and the accession number is NP_001333870.1.
TMPK-00429	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi) HERV7Q,HER-2,HER2,NGL,EGFR2,ENVW,NEU,MLN 19,HERVW,C...	Human	HEK293 Cells
	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.5 kDa and the accession number is P04626-1.
TMPK-00428	HER2/ErbB2 Protein, Human, Recombinant (His & Avi) MLN 19,HER2,HER-2,HERVW,EGFR2,ENV,ERBB2,NEU,HERV7Q,...	Human	HEK293 Cells
	ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.
TMPK-00430	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated MLN19,HERV7Q,HERVW,MLN 19,TKR1,herstatin,ENVW,EGFR2...	Human	HEK293 Cells
	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.5 kDa and the accession number is P04626-1.
TMPY-02361	VEGFR2/KDR Protein, Human, Recombinant (His) VEGFR2,kinase insert domain receptor,VEGFR...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession number is P35968-1.
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Vascular endothelial growth factor receptor 1,Vascular perme...	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Flt-4,VEGFR-3,Chy,fms related tyrosine kinase 4,V	Mouse	HEK293 Cells
	VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1.
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His) VEGFR-3,PCL,FLT41,VEGF Receptor 3,VEGFR3,F...	Human	HEK293 Cells
	VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is P35916-1.
TMPK-00451	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated FLT,Flt-1,FRT,VEGFR1,VEGF R1,FLT1	Human	HEK293 Cells
	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 85.1 kDa and the accession number is P17948-1.
TMPK-00445	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) PCL,PCLFLT41,VEGFR3,FLT-4,LMPH1A,FLT-41,VEGFR	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery. VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 87.4 k...
TMPY-04796	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) FLK1,kinase insert domain receptor,CD309,VEGFR2,Flk...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is P35968-1.
TMPY-02736	VEGFR2/KDR Protein, Mouse, Recombinant (His) sVEGFR-2,6130401C07,kinase insert domain receptor,V...	Mouse	HEK293 Cells
	VEGFR2/KDR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and the accession number is P35918-1.
TMPY-02858	VEGFR2/KDR Protein, Mouse, Recombinant (hFc) VEGFR2,6130401C07,Krd-1,kinase insert domain recept...	Mouse	HEK293 Cells
	VEGFR2/KDR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110 kDa and the accession number is P35918.
TMPY-04530	VEGFR2/KDR Protein, Human, Recombinant (His & GST) Flk-1,VEGFR2,kinase insert domain receptor,FLK1,CD3...	Human	Baculovirus Insect Cells
	VEGFR2/KDR Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.3 kDa and the accession number is P35968-1.
TMPK-00454	VEGFR2/KDR Protein, Human, Recombinant (His & Avi) VEGFR-21,Ly73,KRD1,VEGFR2,CD309,FLK1,V...	Human	HEK293 Cells
	Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. VEGFR2/KDR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-H...
TMPY-01937	VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) VEGFR-3,fms related tyrosine kinase 4,VEGFR	Mouse	HEK293 Cells
	VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P35917-1.
TMPJ-00414	VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated Protein-tyrosine kinase receptor flk-1,KDR,Kinase insert dom...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 120-150 KDa and the accession number is P35968.
TMPY-04940	VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated Flk-1,kinase insert domain receptor,VEGFR,CD309,V	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession number is P35968-1.
TMPK-00450	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) FLT1,FRT,FLT,Flt-1,VEGF R1,VEGFR1	Human	HEK293 Cells
	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 85.1 kDa and the accession number is P17948-1.
TMPK-00446	VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated PCL,FLT-41,LMPH1A,FLT-4,VEGFR3,PCLFLT41,VEGFR	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery. VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m...
TMPY-01069	VEGFR3/FLT4 Protein, Human, Recombinant (hFc) FLT41,fms related tyrosine kinase 4,VEGF Receptor 3,PCL,FLT-...	Human	HEK293 Cells
	VEGFR3/FLT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.3 kDa and the accession number is P35916-1.
TMPY-04802	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) kinase insert domain receptor,CD309,VEGFR2,FLK1,Flk...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.4 kDa and the accession number is P35968-1.
TMPY-05610	VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated Flk-1,VEGFR,kinase insert domain receptor,VEGFR...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 86.5 kDa and the accession number is P35968-1.
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重组蛋白

EGFR Protein, Human, Recombinant (His)

Cat.No: TMPY-00742

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04818

Species: Cynomolgus

Expression System: HEK293 Cells

EGFR Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02676

Species: Mouse

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00426

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00902

Species: Rhesus

Expression System: HEK293 Cells

EGFR vIII Protein, Human, Recombinant (His)

Cat.No: TMPJ-00648

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled

Cat.No: TMPK-00425

Species: Human

Expression System: HEK293 Cells

EGFR vIII Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00647

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00427

Species: Human

Expression System: HEK293 Cells

EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00646

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)

Cat.No: TMPY-04529

Species: Human

Expression System: Baculovirus Insect Cells

CLEC14A Protein, Human, Recombinant (His)

Cat.No: TMPK-01073

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01043

Species: Human

Expression System: HEK293 Cells

EGFRVIII Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00691

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Rat, Recombinant (His)

Cat.No: TMPY-02958

Species: Rat

Expression System: HEK293 Cells

EGFR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02675

Species: Mouse

Expression System: HEK293 Cells

EGFR Protein, Canine, Recombinant (His)

Cat.No: TMPY-03724

Species: Canine

Expression System: Baculovirus Insect Cells

EGFR Protein, Feline, Recombinant (His)

Cat.No: TMPY-06524

Species: Feline

Expression System: Baculovirus Insect Cells

EGFR Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-00128

Species: Rhesus

Expression System: HEK293 Cells

EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled

Cat.No: TMPK-00689

Species: Human

Expression System: HEK293 Cells

EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled

Cat.No: TMPK-00690

Species: Human

Expression System: HEK293 Cells

EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00692

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (Isoform Viii, hFc)

Cat.No: TMPY-05258

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated

Cat.No: TMPY-06593

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)

Cat.No: TMPY-05211

Species: Human

Expression System: Baculovirus Insect Cells

EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated

Cat.No: TMPY-05612

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)

Cat.No: TMPY-06549

Species: Human

Expression System: HEK293 Cells

EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated

Cat.No: TMPY-05637

Species: Human

Expression System: Baculovirus Insect Cells

HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00429

Species: Human

Expression System: HEK293 Cells

HER2/ErbB2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00428

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00430

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (His)

Cat.No: TMPY-02361

Species: Human

Expression System: HEK293 Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00412

Species: Human

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01936

Species: Mouse

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00949

Species: Human

Expression System: HEK293 Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00451

Species: Human

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00445

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)

Cat.No: TMPY-04796

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02736

Species: Mouse

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02858

Species: Mouse

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04530

Species: Human

Expression System: Baculovirus Insect Cells

VEGFR2/KDR Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00454

Species: Human

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01937

Species: Mouse

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated

Cat.No: TMPJ-00414

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04940

Species: Human

Expression System: HEK293 Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00450

Species: Human

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated

Cat.No: TMPK-00446

Species: Human

Expression System: HEK293 Cells

VEGFR3/FLT4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01069

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)

Cat.No: TMPY-04802

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05610

Species: Human

Expression System: HEK293 Cells

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