D4'

N-acetyl Dapsone-D4 is the deuterium-labeled metabolite of Dapsone.

Haloperidol-D4 is deuterium-labeled haloperidol. Haloperidol (T0025) is a dopamine D2 receptor antagonist.

Leukotriene D4 (LTD4) 是一种由花生四烯酸形成的强效促炎介质，是一种支气管收缩剂，可诱导成骨细胞衰老。Leukotriene D4 诱导潜在致癌基因的转录活性，可用于研究哮喘。

Amoxicillin-D4 is a deuterium-labeled Amoxicillin. Amoxicillin (T1005) is an antibiotic with broad-spectrum antimicrobial activity.

Aprocitentan-D4 is a deuterium-labeled Aprocitentan. Aprocitentan (T7817) is a major and pharmacologically active metabolite of Macitentan. Aprocitentan (T7817) is a dual ETA/ETB antagonist (IC50s: 3.4 nM and 987 nM; pA2s: 6.7 and 5.5).

Bexarotene-D4 is a deuterium-labeled Bexarotene (T6410) (LGD1069). Bexarotene is a selective RXR agonist used in the treatment of cutaneous T-cell lymphoma.

Candesartan-D4是Candesartan (T1461)的氘代物，可用于同位素示踪。Candesartan是一种强效、口服活性的血管紧张素 II AT1 受体阻滞剂和 PPAR-γ 激动剂，具有持久的抗高血压作用，常在药代动力学分析中作为内标使用。

Cetirizine-D4 is a deuterium-labeled Cetirizine. Cetirizine (T0089L) is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.

Dabigatran-D4 hydrochloride is deuterium-labeled dabigatran,which is a reversible and selective direct thrombin inhibitor (DTI)with a Ki value of 4.5 nM.

Delamanid-D4 is deuterium-labeled Delamanid. Delamanid (T4202) is a newer mycobacterial cell wall synthesis inhibitor that inhibits the synthesis of mucus acid.

Dofetilide-D4 (UK 68789 D4)，a deuterium-labeled version of Dofetilide，is categorized as a Class III antiarrhythmic medication.

Enclomiphene-D4 hydrochloride ( (E)-Clomiphene D4 hydrochloride; trans-Clomiphene D4 hydrochloride; Enclomifene D4 hydrochloride) is a potent and orally active oestrogen receptor antagonist,with antioestrogenic property.Enclomiphene D4 hydrochloride ( (E)-Clomiphene D4 hydrochloride; trans-Clomiphene D4 hydrochloride; Enclomifene D4 hydrochloride) is a deuterium labeled Enclomiphene.

Etoricoxib-D4是2H 标记的 Etoricoxib (T1574)。Etoricoxib是一种合成的非甾体抗炎化合物，是可口服且具有选择性的 COX-2 抑制剂，具有解热、镇痛和潜在的抗肿瘤特性。

Etravirine (T2551) is a non-nucleoside reverse transcriptase inhibitor (NNRTI)used for the treatment of HIV. Etravirine-D4 is the deuterium labeled Etravirine.

Haloperidol-D4 is deuterium-labeled Haloperidol (T0025).

Hydroxyzine-D4 is a deuterium-labeled variation of Hydroxyzine,a chemical compound known for its anticholinergic,anxiolytic,and analgesic properties. It is classified as a heterocyclic histamine H1-receptor antagonist.

Imatinib-D4 is a deuterium-labeled Imatinib. Imatinib (T6230) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL,PDGFR,v-Abl,and c-kit kinase activity.

Indomethacin-D4 is a deuterium labeled Indomethacin. Indomethacin (T0458) is a potent and nonselective inhibitor of COX1 and COX2,with IC50s of 18 nM and 26 nM for human COX-1 and COX-2,respectively,in CHO cells.

Irbesartan-D4是Irbesartan (T1615)的氘代化合物，是血管紧张素受体阻滞剂，可用于研究心血血管疾病。

Lansoprazole Sulfide-D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide (T21128) is an orally active anti-TB (Mycobacterium tuberculosis)agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole.

Losartan (D4 Carboxylic Acid) is the deuterium labeled Losartan Carboxylic Acid (T3461),which is an angiotensin II receptor antagonist.

Losartan-D4是Losartan的氘代标记物，可用于同位素示踪。Losartan是一种血管紧张素II (angiotensin II)受体拮抗剂 (IC50=20 nM)。

Macitentan-D4是一种 Macitentan (T2561)氘代物，可被当作非多肽 ETA 和 ETB  (内皮素受体)双拮抗剂。Macitentan-D4 比 Macitentan (T2561)毒性更低，半衰期更长，可用于研究由内皮素受体介导介导的疾病。

Nitazoxanide-D4 is the deuterium labeled Nitazoxanide (T1546).