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Cat. No. Product Name
L5900 血脑屏障通透化合物库

509 compounds
509 个 CNS-Penetrant 生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L3300 组胺&褪黑色素化合物库

153 compounds
153 种生物活性小分子化合物,用于高通量、高内涵筛选;
L7700 神经再生化合物库

524 compounds
524 种神经再生相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2610 神经递质受体化合物库

1513 compounds
1513 种与神经递质受体相关的化合物,用于高通量、高内涵筛选;
L9840 抗阿尔茨海默症化合物库

986 compounds
986 种阿尔茨海默症相关的化合物集合,可用于高通量和高内涵筛选;
L4300 Wnt/Hedgehog/Notch 通路化合物库

237 compounds
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。
L2630 神经元分化化合物库

672 compounds
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发
L6750 活血化瘀中药单体库

580 compounds
580种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。
L7110 抗高血压化合物库

678 compounds
678 种高血压相关的小分子,用于高通量和高内涵筛选;

化合物库

血脑屏障通透化合物库
Cat.No: L5900
Compounds: 509
组胺&褪黑色素化合物库
Cat.No: L3300
Compounds: 153
神经再生化合物库
Cat.No: L7700
Compounds: 524
神经递质受体化合物库
Cat.No: L2610
Compounds: 1513
抗阿尔茨海默症化合物库
Cat.No: L9840
Compounds: 986
Wnt/Hedgehog/Notch 通路化合物库
Cat.No: L4300
Compounds: 237
神经元分化化合物库
Cat.No: L2630
Compounds: 672
活血化瘀中药单体库
Cat.No: L6750
Compounds: 580
抗高血压化合物库
Cat.No: L7110
Compounds: 678
Cat. No. Product Name Target Signaling Pathways
T39246 Brain Natriuretic Peptide-45, mouse

Brain Natriuretic Peptide-45, mouse,BNP-45, mouse

Mouse Brain Natriuretic Peptide-45 (BNP-45, mouse) is a circulating variant of the mouse brain natriuretic peptide derived from the mouse heart. It exhibits powerful hypotensive and natriuretic properties.
TP1207 Brain Natriuretic Peptide-45, rat

BNP-45 (rat),Brain natriuretic peptide-45 rat

BNP-45 (rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.
T83905 Brain Natriuretic Peptide-32 (rat) acetate

BNP (14-45),B-type Natriuretic Peptide-32,Brain Natriuretic Polypeptide-32,BNP-32

BNP-32(Brain natriuretic peptide-32)是心血管激素前体proBNP的肽段,能够结合大鼠血管平滑肌上的利钠肽受体(IC50 = 7.3 nM),并在同样的细胞中促进cGMP积累(EC50 = 170 nM)。BNP-32还能使经去甲肾上腺素预收缩的孤立大鼠主动脉条带松弛(EC50 = 6.7 nM),当以3 µg/kg的剂量给药时,能增加大鼠的尿量和尿液电解质排泄,并诱导低血压。
TP1756 Brain Natriuretic Peptide (1-32), rat

Brain Natriuretic Peptide (BNP) (1-32), rat

Brain Natriuretic Peptide (BNP) (1-32), rat is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).Brain natriuretic peptide (type B natriuretic peptide) was origin
T35832 Brain Natriuretic Peptide (1-32), rat acetate

Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide hormone synthesized by ventricular cardiomyocytes as a result of myocardial cell stretching (cardiomyocyte distension)[1].
T37819 Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. It also shares sequence homology with the known neuropeptides neuromedin C , bombesin , neuromedin K , substance K , substance P , physalaemin, and eledoisin. aFGF (102-111) corresponds to amino acid residues 102-111 of the fulllength pept...
T37820 Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)

Brain-derived basic fibroblast growth factor (1-24) (brain-derived bFGF) is a peptide fragment of brain-derived bFGF. bFGF is a peptide produced in bovine brain that is protective in a rat model of pressure-induced retinal ischemia. bFGF (1-24) corresponds to amino acid residues 1-24 of the full length peptide.
T37595 Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. aFGF (1-11) corresponds to amino acid residues 1-11 of the full length peptide.
T82823 Brain Natriuretic Peptide-45, rat TFA

BNP-45, rat TFA

Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) 为来源于大鼠心脏的脑利钠肽循环同源物,具有显著的降压和利尿效果。
T76321 Brain Derived Basic Fibroblast Growth Factor (1-24)

Brain Derived BasicFibroblast Growth Factor(1-24) (FGF basic 1-24) 是一种合成肽,表现出抗细菌和抗HBV 的活性。Brain Derived BasicFibroblast Growth Factor(1-24) 可用于感染性疾病和免疫性疾病的研究。
T15275 Fenobam

GluR Neuroscience
Fenobam 是可口服的、可穿过血脑屏障的 mGluR5拮抗剂,具有抗焦虑活性,在大鼠和人重组 mGlu5 受体上的 Kd 值分别 54 和 31 nM。它有反向激动剂活性,可阻断 mGlu5 受体活性,IC50为 84 nM。
TP1208 Nesiritide

BNP-32,Brain Natriuretic Peptide-32 human,奈西立肽

Nesiritide is the recombinant form of the 32 amino acid human B-type natriuretic peptide, which is normally produced by the ventricular myocardium. It is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR
T8548 Metoprine

Histone Methyltransferase; Antifolate; Histamine Receptor Cell Cycle/Checkpoint; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Metoprine 是一种有效的组胺 N-甲基转移酶抑制剂,具有抗肿瘤活性。它是一种二氨基嘧啶衍生物,可以透过血脑屏障,并通过抑制 HMT 增加脑组胺水平。
T9346 CVN424

GPR Endocrinology/Hormones; GPCR/G Protein
CVN424 是一种有效的、具有口服活性的、选择性的GPR6反向激动剂,其EC50=9.4 nM,EC50=38 nM。它可以透过血脑屏障,对帕金森病具有潜在的研究价值。
T9452 PW0787

GPR Endocrinology/Hormones; GPCR/G Protein
PW0787 是一种可透过血脑屏障的,口服具有活性的GPR52选择性激动剂 (EC50=135 nM)。它能够抑制精神刺激行为。
TP1206 BNP-45 (rat) (TFA) (123337-89-3 free base)

BNP-45 (rat) (TFA),Brain natriuretic peptide-45 rat TFA

BNP-45 (rat) TFA is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.
TN7044 S-(4-Hydroxybenzyl)glutathione

GluR Neuroscience
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] 是一种谷胱甘肽衍生物,能够抑制红藻氨酸与脑谷氨酸受体的体外结合(IC50:2 μM)。
T9466 RTICBM-189

Others Others
RTICBM-189 是可透过血脑屏障的大麻素 1 型受体变构调节剂,在 Ca2+动员试验中pIC50为 7.54,对 hCB1和 mCB1的 pIC50分别为 5.29 和 6.25。
TP1209 BNP (1-32), rat TFA (133448-20-1 free base)

Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA

Acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body\'s sa
T4081 MPTP hydrochloride

MPTP-hydrochloride

Apoptosis; Dopamine Receptor Apoptosis; GPCR/G Protein; Neuroscience
MPTP hydrochloride 是 MPP+ 的前体,是一种多巴胺神经毒素,具有血脑屏障渗透性。MPTP hydrochloride 对多巴胺能神经元有毒,可以导致帕金森症,被广泛应用于帕金森动物模型的构建。
TP1856 Colivelin

Beta Amyloid; STAT JAK/STAT signaling; Neuroscience; Stem Cells
Colivelin 是一种神经保护肽和 STAT3 的激活剂,是一种合成的杂合肽,可增强 humanin (HN) 的神经保护作用。它通过激活 STAT3 在体外抑制神经元死亡,具有潜力用于阿尔茨海默病和缺血性脑损伤的相关研究。
T2625 MK-0752

Beta Amyloid; Gamma-secretase Neuroscience; Proteases/Proteasome; Stem Cells
MK0752 是一种高效的、特异性的、可穿过血脑屏障的、口服活性的 γ-分泌酶(γ-secretase)抑制剂,对人 SH-SY5Y 细胞 Aβ40 呈剂量依赖性降低(IC50=5 nM)。它能够降低体内新生的中枢神经系统 Aβ。
T21747 VU0483605

GluR Neuroscience
VU0483605 是一种有效的特异性 mGluR1 正变构调节剂,对人和大鼠的 EC50 分别为 390 和 356 nM。
T8554 KCC-07

DNA Alkylator/Crosslinker DNA Damage/DNA Repair
KCC-07 是一种甲基-CpG 结合域蛋白 2 (MBD2) 的选择性、强效和脑渗透抑制剂,具有抗癌活性。它阻止 MBD2 与甲基化 DNA 结合并激活脑特异性血管生成抑制剂 1,诱导抗增殖 BAI1/p53/p21 信号传导。
T15108 DG-041

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
DG-041 是高亲和力,选择性的,有效的 EP3受体拮抗剂,在结合和 FLIPR 试验中,IC50分别为 4.6 nM 和 8.1 nM。DG-041通过抑制 PGE2促进血小板聚集。DG-041具有血脑屏障渗透性。
T16550 PKR-IN-C16

Others Others
PKR-IN-C16 是一种特异性蛋白激酶抑制剂。它能够抑制 PKR 的自磷酸化,解除 PKR 在原代神经元细胞培养中诱导的翻译阻断。
T9697 ASK1-IN-1

ASK Apoptosis
ASK1-IN-1 是一种凋亡信号调节激酶 1(SK1) 抑制剂,具有良好的效价 (细胞IC50=138 nM; BiochemicalIC50=21 nM)。ASK1-IN-1具有中枢神经系统渗透性。
T22428 Sodium Glucoheptonate

Sodium glucoheptonate,葡萄醣庚酸钠

Others Others
Sodium Glucoheptonate (Sodium glucoheptonate) 可用作 Tc-99m 放射性标记的试剂盒,也可用于清洗金属、丝光、脱漆和铝蚀刻。其中Tc-99m glucoheptonate 是一种肾脏和脑部成像剂,可用于检测脑肿瘤。
T22782 FGIN-1-27

Others Others
FGIN 1-27 是一种吲哚乙酰胺,是外周苯二氮卓受体的特异性的配体,Ki 为 5.0 nM。FGIN 1-27 可以透过血脑屏障。FGIN 1-27对异烟肼引起的抽搐发作具有抑制作用。
T12998 SR10067

Others; Autophagy Autophagy; Others
SR10067 是选择性的Rev-Erbα/β的激动剂,其对Rev-Erbβ 和Rev-Erbα 的IC50分别为 160 nM 和 170 nM。SR10067可以透过大脑的。SR10067具有抗焦虑活性。
T15802 LY2183240

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
LY2183240 是大麻素摄取阻滞剂。它是内源性大麻素降解酶脂肪酸酰胺水解酶的有效共价抑制剂。它抑制脂肪酸酰胺水解酶 (FAAH) 活性,IC50 为12.4 nM。它也抑制其他几种脑丝氨酸水解酶,对 MAG 脂肪酶、bh6 和 KIAA1363 的 IC50分别为 5.3、0.09 和 8.2 nM。
T2225 4-Hydroxyantipyrine

COX Immunology/Inflammation; Neuroscience
4-Hydroxyantipyrine 是在氨基比林的氧化脱氨过程中形成的。
T24055 FAUC 213

FAUC213,FAUC-213

Dopamine Receptor GPCR/G Protein; Neuroscience
FAUC 213 是一种具有口服活性的‘、高度选择性的、可透过血脑屏障的多巴胺 D4受体完全拮抗剂,对 hD4.4的 Ki=2.2 nM。它对 D2和 D3受体的活性较低,对于 hD2、hD3的 Ki 分别为 3.4 μM、5.3 μM。它表现出非典型的抗精神病活性。
T3707 GNE-3511

GNE3511

DNA Alkylation; MAPK DNA Damage/DNA Repair; MAPK
GNE-3511是双亮氨酸拉链激酶 (DLK)抑制剂(Ki:0.5 nM)。
T27620 IP7e

IP 7e,IP-7e,isoxazolo-pyridinone 7e

Others Others
IP7e (isoxazolo-pyridinone 7e) 是一种 Nurr1 激活剂,EC50 值为 3.9 nM。
T5465 PF-5274857

PF-5274857 freebase

Smo Stem Cells
PF-5274857 (PF-5274857 free base) freebase 是有效的、具有口服活性的、选择性的、可透过血脑屏障的 Smo 拮抗剂,其 IC50=5.8 nM,Ki=4.6 nM。它有用于包括激活的 Hh 途径驱动的脑肿瘤和脑转移在内的多种肿瘤的研究潜力。
T9232 Mitochondrial fusion promoter M1

Mitochondrial Metabolism Metabolism
Mitochondrial fusion promoter M1 是一种线粒体动态调节剂,能够保持线粒体功能并促进细胞呼吸,减轻心肌缺血/再灌注大鼠的心脏损伤和大脑损伤。
T21995 XAP044

GluR Neuroscience
XAP044 是高效的选择性mGlu7拮抗剂。代谢型谷氨酸受体亚型 7 是哺乳动物 CNS 中神经传递的重要突触前调节剂。它在啮齿动物行为测试中表现出较好的大脑暴露、广谱抗应激、抗抑郁以及抗焦虑作用。
T11799 L-745870 hydrochloride

Dopamine Receptor GPCR/G Protein; Neuroscience
L-745870 hydrochloride 是可透过血脑屏障的、选择性的、具有口服活性的多巴胺 D4受体拮抗剂,Ki=0.43 nM。它对 D2(Ki 为 960 nM) 和 D3(Ki 为 2300 nM) 受体的亲和力相对较弱,对 5-HT2受体,sigma 位点和 α-肾上腺素受体表现出中等亲和力。
T21793 CGP 35348

GABA Receptor Membrane transporter/Ion channel; Neuroscience
CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。
T6031 GNE0877

GNE 0877,GNE-0877

LRRK2 Autophagy
GNE0877 (GNE 0877) 是一种高效且特异性的富含亮氨酸的重复激酶 2(LRRK2) 抑制剂,IC50为3 nM,Ki 为0.7 nM
T3119 JNJ-63533054

JNJ 63533054

GPR Endocrinology/Hormones; GPCR/G Protein
JNJ-63533054 是一种选择性的,具有口服活性的GPR139激动剂,对人GPR139的EC50为 16 nM。它可穿过血脑屏障,对 GPR139 的选择性高于其他 GPCR、离子通道和转运蛋白。
T1065 Baclofen

巴氯芬,Lioresal

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Baclofen (Lioresal) 是 γ-氨基丁酸 (GABA) 的亲脂性衍生物,是可口服的选择性代谢型 GABA-B 受体激动剂,具有高血脑屏障渗透率,用于治疗因脊髓损伤和多发性硬化引起的痉挛。
T2009 SB-3CT

MMP Proteases/Proteasome
SB-3CT 是一种可透过血脑屏障的、竞争性的金属蛋白酶MMP-2和MMP-9抑制剂,Ki 分别为 13.9 nM、600 nM。他对明胶酶具有高选择性。它具有神经保护和抗癌作用。
T0084 Moclobemide

吗氯贝胺,Ro111163

MAO; Monoamine Oxidase Metabolism; Neuroscience
Moclobemide (Ro111163) 是可逆的、可透过血脑屏障的单胺氧化酶 (MAO-A) 抑制剂,能够抑制 hMAO-A (IC50=6.061 μM)。它上调慢性应激小鼠海马祖细胞的增殖。
TP1264 Prolylleucine

((Benzyloxy)carbonyl)-L-prolyl-D-leucine

Others Others
Prolylleucine (((Benzyloxy)carbonyl)-L-prolyl-D-leucine) 是一种二肽,含有支链氨基酸,可以影响动物的昼夜节律和行为。
T9687 MAGL-IN-4

His121 ARG57

Lipase Metabolism
MAGL-IN-4 (His121 ARG57) 是选择性的、口服有效的、可透过血脑屏障的、可逆的单酰基甘油脂肪酶抑制剂,IC50=6.2 nM。它主要通过大脑中选择性抑制 MAGL 增加 2-花生四烯酰甘油水平来增强内源性大麻素信号。
T8778 TTK21

Epigenetic Reader Domain Chromatin/Epigenetic
TTK21 是 CBP/p300 组蛋白乙酰转移酶活性的激活剂,与葡萄糖基碳纳米球结合时,可通过血脑屏障,对成人大脑神经发生和长期记忆功能有益。
T1993 J-147

J147

Epigenetic Reader Domain; Dopamine Receptor; Monoamine Oxidase Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
J-147 是一种高效的、具有口服活性的、可透过血脑屏障神经保护剂,可增强认知能力。它抑制单胺氧化酶 B 和多巴胺转运体,EC50分别为 1.88 μM 和 0.649 μM。它有研究阿尔茨海默氏症的潜力。
T0082 Domperidone

R33812,多潘立酮

Dopamine Receptor GPCR/G Protein; Neuroscience
Domperidone (R33812) 是多巴胺 2 受体拮抗剂,能够影响胃和小肠的化学感受器触发区和运动功能,具有止吐和促动力作用。

化合物

Brain Natriuretic Peptide-45, mouse
Cat.No: T39246
Synonym: Brain Natriuretic Peptide-45, mouse,BNP-45, mouse
Target:
Brain Natriuretic Peptide-45, rat
Cat.No: TP1207
Synonym: BNP-45 (rat),Brain natriuretic peptide-45 rat
Target:
Brain Natriuretic Peptide-32 (rat) acetate
Cat.No: T83905
Synonym: BNP (14-45),B-type Natriuretic Peptide-32,Brain Natriuretic Polypeptide-32,BNP-32
Target:
Brain Natriuretic Peptide (1-32), rat
Cat.No: TP1756
Synonym: Brain Natriuretic Peptide (BNP) (1-32), rat
Target:
Brain Natriuretic Peptide (1-32), rat acetate
Cat.No: T35832
Synonym:
Target:
Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)
Cat.No: T37819
Synonym:
Target:
Brain-Derived Basic Fibroblast Growth Factor (1-24) (bovine) (trifluoroacetate salt)
Cat.No: T37820
Synonym:
Target:
Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)
Cat.No: T37595
Synonym:
Target:
Brain Natriuretic Peptide-45, rat TFA
Cat.No: T82823
Synonym: BNP-45, rat TFA
Target:
Brain Derived Basic Fibroblast Growth Factor (1-24)
Cat.No: T76321
Synonym:
Target:
Fenobam
Cat.No: T15275
Synonym:
Target: GluR
Nesiritide
Cat.No: TP1208
Synonym: BNP-32,Brain Natriuretic Peptide-32 human,奈西立肽
Target:
Metoprine
Cat.No: T8548
Synonym:
Target: Histone Methyltransferase, Antifolate, Histamine Receptor
CVN424
Cat.No: T9346
Synonym:
Target: GPR
PW0787
Cat.No: T9452
Synonym:
Target: GPR
BNP-45 (rat) (TFA) (123337-89-3 free base)
Cat.No: TP1206
Synonym: BNP-45 (rat) (TFA),Brain natriuretic peptide-45 rat TFA
Target:
S-(4-Hydroxybenzyl)glutathione
Cat.No: TN7044
Synonym:
Target: GluR
RTICBM-189
Cat.No: T9466
Synonym:
Target: Others
BNP (1-32), rat TFA (133448-20-1 free base)
Cat.No: TP1209
Synonym: Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA
Target:
MPTP hydrochloride
Cat.No: T4081
Synonym: MPTP-hydrochloride
Target: Apoptosis, Dopamine Receptor
Colivelin
Cat.No: TP1856
Synonym:
Target: Beta Amyloid, STAT
MK-0752
Cat.No: T2625
Synonym:
Target: Beta Amyloid, Gamma-secretase
VU0483605
Cat.No: T21747
Synonym:
Target: GluR
KCC-07
Cat.No: T8554
Synonym:
Target: DNA Alkylator/Crosslinker
DG-041
Cat.No: T15108
Synonym:
Target: Prostaglandin Receptor
PKR-IN-C16
Cat.No: T16550
Synonym:
Target: Others
ASK1-IN-1
Cat.No: T9697
Synonym:
Target: ASK
Sodium Glucoheptonate
Cat.No: T22428
Synonym: Sodium glucoheptonate,葡萄醣庚酸钠
Target: Others
FGIN-1-27
Cat.No: T22782
Synonym:
Target: Others
SR10067
Cat.No: T12998
Synonym:
Target: Others, Autophagy
LY2183240
Cat.No: T15802
Synonym:
Target: FAAH, Autophagy
4-Hydroxyantipyrine
Cat.No: T2225
Synonym:
Target: COX
FAUC 213
Cat.No: T24055
Synonym: FAUC213,FAUC-213
Target: Dopamine Receptor
GNE-3511
Cat.No: T3707
Synonym: GNE3511
Target: DNA Alkylation, MAPK
IP7e
Cat.No: T27620
Synonym: IP 7e,IP-7e,isoxazolo-pyridinone 7e
Target: Others
PF-5274857
Cat.No: T5465
Synonym: PF-5274857 freebase
Target: Smo
Mitochondrial fusion promoter M1
Cat.No: T9232
Synonym:
Target: Mitochondrial Metabolism
XAP044
Cat.No: T21995
Synonym:
Target: GluR
L-745870 hydrochloride
Cat.No: T11799
Synonym:
Target: Dopamine Receptor
CGP 35348
Cat.No: T21793
Synonym:
Target: GABA Receptor
GNE0877
Cat.No: T6031
Synonym: GNE 0877,GNE-0877
Target: LRRK2
JNJ-63533054
Cat.No: T3119
Synonym: JNJ 63533054
Target: GPR
Baclofen
Cat.No: T1065
Synonym: 巴氯芬,Lioresal
Target: GABA Receptor
SB-3CT
Cat.No: T2009
Synonym:
Target: MMP
Moclobemide
Cat.No: T0084
Synonym: 吗氯贝胺,Ro111163
Target: MAO, Monoamine Oxidase
Prolylleucine
Cat.No: TP1264
Synonym: ((Benzyloxy)carbonyl)-L-prolyl-D-leucine
Target: Others
MAGL-IN-4
Cat.No: T9687
Synonym: His121 ARG57
Target: Lipase
TTK21
Cat.No: T8778
Synonym:
Target: Epigenetic Reader Domain
J-147
Cat.No: T1993
Synonym: J147
Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase
Domperidone
Cat.No: T0082
Synonym: R33812,多潘立酮
Target: Dopamine Receptor
Cat. No. Product Name Target Signaling Pathways
T8392 L(+)-Asparagine monohydrate

Endogenous Metabolite Metabolism
L(+)-Asparagine monohydrate 是一种非必需氨基酸,参与组织细胞功能的神经和代谢调节。
T0795 Rutin

Quercetin 3-O-rutinoside,芦丁,Rutoside

Beta Amyloid; Prostaglandin Receptor; Autophagy Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Rutin (Quercetin 3-O-rutinoside) 是槐果实中的一种黄酮类天然产物,具有抗炎、降糖、抗氧化、神经保护、肾脏保护、肝脏保护和降低Aβ低聚物活性等多种生物活性。它能穿过血脑屏障,通过抑制细胞凋亡、线粒体功能紊乱和氧化应激抑制万古霉素诱导的肾小管细胞凋亡。
T0130 Physostigmine Salicylate

水杨酸依色林,水杨酸毒扁豆碱

AChR; AChE Neuroscience
Physostigmine salicylate 是一种可逆的乙酰胆碱酯酶抑制剂,也一种是抗胆碱能中毒的解毒剂。它可透过血脑屏障并刺激中枢胆碱能神经传递。它能逆转阿尔茨海默病转基因小鼠的记忆缺陷。
T3S0870 Paederosidic acid methyl ester

鸡屎藤苷酸甲酯,紫草酸甲酯

ATPase; Potassium Channel; NO Synthase Immunology/Inflammation; Membrane transporter/Ion channel
Paederosidic acid methyl ester 是 ATP 敏感的 K+channel 通道激活剂,分离自 P. scandens。它通过激活脑中和脊髓水平中 ATP 敏感型 K+通道提高了痛觉阈值,表现出显著的中枢缓解疼痛活性。
T0492 Dimethyl fumarate

富马酸二甲酯,DMF

Reactive Oxygen Species; HIV Protease; Nrf2; Endogenous Metabolite; Autophagy Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Dimethyl fumarate (DMF) 是具有口服活性且可透过血脑屏障的Nrf2激活剂,可诱导抗氧化剂基因表达上调。它是一种富马酸盐衍生物,可作抗炎和免疫调节剂,可研究多发性硬化症。
T0848 L-DOPA

左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine

Dopamine Receptor; Endogenous Metabolite GPCR/G Protein; Metabolism; Neuroscience
L-DOPA (Levodopa) 是的神经递质多巴胺的代谢前体,具有口服活性。Levodopa 能够透过血脑屏障,并在大脑中转化为多巴胺。Levodopa 具有抗痛觉过敏作用。Levodopa 还具有帕金森氏病的研究潜力。
T22417 Rutin hydrate

芦丁,Rutoside,Sophorin,Quercetin-3-O-rutinoside

Beta Amyloid; Others; Autophagy Autophagy; Neuroscience; Others
Rutin hydrate (Sophorin) 是一种广泛存在于多种植物中的黄酮类天然产物,具有降糖、抗炎、抗氧化、神经保护、肾脏保护、肝脏保护和降低 Aβ 低聚物活性等多种生物活性。它能穿过血脑屏障,通过抑制细胞凋亡、线粒体功能紊乱和氧化应激抑制万古霉素诱导的肾小管细胞凋亡。
T36857L Premarin

共轭雌激素,Estrone 3-sulfate,Estrone sulfate

Estrogen Receptor/ERR Endocrinology/Hormones
Premarin (Estrone 3-sulfate) 是一种硫酸雌激素,在创伤性脑损伤期间具有神经保护作用。
T4779 4-Methylcatechol

p-Methylcatechol,3,4-二羟基甲苯,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene

Others; Endogenous Metabolite Metabolism; Others
4-Methylcatechol (3,4-Dihydroxytoluene) 是 p-toluate 的代谢物,它是 Catechol 2,3-Dioxygenase 的自杀性底物抑制剂。
TQ0285 Spaglumic acid

异冬谷酸,N-Acetylaspartylglutamic acid,NAAG

Endogenous Metabolite Metabolism
Spaglumic acid (N-Acetylaspartylglutamic acid) 是一种神经肽,在脑中以毫摩尔浓度存在。
T4708 D-N-Acetylgalactosamine

D-GalNAc,N-Acetyl-D-galactosamine,N-乙酰-D-半乳糖胺

Others; Endogenous Metabolite Metabolism; Others
D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) 是脑杂多糖(糖蛋白)的重要组成部分。
T5739 Paederosidic acid

鸡屎藤苷酸,异戊二酸 紫草酸

Apoptosis; BCL Apoptosis
Paederosidic acid 是从鸡矢藤分离出的一种天然产物,通过诱导线粒体介导的凋亡抑制肺癌细胞,具有显着的抗肿瘤、抗惊厥和镇静作用。
T4S1725 Galanthamine

Galantamine,加兰他敏

Apoptosis; AChE Apoptosis; Neuroscience
Galanthamine (Galantamine) 是一种乙酰胆碱酯酶抑制剂,IC50为 500 nM。
TN6706 3-demethylcolchicine

3-去甲秋水仙碱,3-去甲基秋水仙碱

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
3-Demethylcolchicine 是一种从金莲花中分离得到的天然产物,对纯化的牛脑微管蛋白的聚合有抑制作用。
T5369 Docosahexaenoic Acid

Cervonic acid,DHA

Others; Endogenous Metabolite Metabolism; Others
Docosahexaenoic Acid 是一种ω-3脂肪酸,在脑和视网膜中较为丰富,且能够直接从鱼油和母乳中获得。
T4881 Phosphorylethanolamine

O-Phosphorylethanolamine,乙醇胺磷酸酯

Others; Endogenous Metabolite Metabolism; Others
Phosphorylethanolamine (O-Phosphorylethanolamine) 是磷脂代谢的一种磷酸单酯代谢物。Phosphorylethanolamine 是磷脂合成的前体,也是磷脂分解的产物。与其他器官相比,大脑中磷酸单酯的含量要高得多。在大脑发育过程中,磷单酯通常在神经增生期间升高。这也与大脑发育过程中正常的程序性细胞死亡和突触修剪的发生相吻合。这些发现与磷酸单酯在膜生物合成中的作用是一致的。Phosphorylethanolamine 与抑制性神经递质GABA和GABAB受体部分激动剂 3-氨基丙基膦酸具有很强的结构相似性。Phosphorylethanolamine 是一种磷单酯,在阿尔茨海默病患者的大脑中减少。
T4S1820 Parishin

巴利森苷A,派立辛,Parishin A

Others Others
Parishin (Parishin A) A 是一种酚类葡萄糖苷,从天麻中分离得到。Parishin 通过调节 Sir2/Uth1/TOR 信号通路而具有抗衰老作用,并延长酵母寿命。
T22300 Creatine monohydrate

Methylguanidoacetic acid monohydrate,一水肌酸

Others; Endogenous Metabolite Metabolism; Others
Creatine monohydrate (Methylguanidoacetic acid monohydrate) 是磷酸原能量系统的关键参与者,尤其是在肌肉和大脑中。 Creatine monohydrate 是高强度、短期活动中 ATP 的主要来源。
TN5118 Taxol C

P-gp Membrane transporter/Ion channel; Neuroscience
Taxol C 可以减少与 P-糖蛋白转运蛋白的相互作用,从而增加紫杉烷类向大脑的渗透。
T16012 Marizomib

NPI-0052,Salinosporamide A,ML858

Proteasome Proteases/Proteasome; Ubiquitination
Marizomib (ML858) 是一种新型不可逆的脑渗透性泛蛋白酶体 (proteasome) 抑制剂,对 20S 蛋白酶体的 CT-L (β5)、CT-T-laspase 样 (C-L, β1) 和胰蛋白酶样 (T-L, β2) 具有抑制作用, IC50 分别为 3.5, 28, 430 nM。
T6S0444 Salvianolic acid A

丹酚酸 A,Dan Phenolic Acid A

MMP Proteases/Proteasome
Salvianolic acid A (Dan Phenolic Acid A) 能够提高抑制基质金属钛酶 9 和抗炎作用,进而保护血脑屏障。
T4732 L-Carnosine

Karnozin,L-肌肽,beta-Alanyl-L-histidine

Antioxidant; Endogenous Metabolite Metabolism; oxidation-reduction
L-Carnosine (Karnozin) 是 由beta-丙氨酸和组氨酸组成的二肽,具有抑制衰老的作用。
T5590 2-(4-Methoxyphenyl)acetic acid

4-Methoxyphenylacetic acid,对甲氧基苯乙酸

Others; Endogenous Metabolite Metabolism; Others
2-(4-Methoxyphenyl)acetic acid (4-Methoxyphenylacetic acid) 是血浆代谢物,具有高度敏感性和特异性,能够作为区分非小细胞癌患者和健康对照组之间的生物指标。
T6S0119 Dauricine

蝙蝠葛碱

Apoptosis; Others; NF-κB Apoptosis; NF-κB; Others
Dauricine 是存在于北豆根粉末中的一种双苯异喹啉生物碱,具有抗炎活性。它通过抑制NF-κB 激活,剂量依赖性地抑制结肠癌细胞的增值和侵袭,并诱导凋亡。
T3262 Phosphocreatine disodium

Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt,磷酸肌酸钠

Others; Endogenous Metabolite Metabolism; Others
Phosphocreatine disodium (Phosphocreatine disodium salt) 是一种磷酸化的肌酸分子,在肌肉、骨骼和大脑中作为一种可快速动员的高能磷酸盐储备。
T3976 Cytosporone B

Csn-B,Dothiorelone G

Others Others
Cytosporone B (Dothiorelone G) 是一种天然存在的核孤儿受体Nur77/NR4A1激动剂(EC50=0.278 nM)。
T64353 4-tert-Octylphenol

Endogenous Metabolite Metabolism
4-tert-Octylphenol 是一种干扰内分泌的化学物质及雌激素药物,能诱导子代小鼠脑神经元祖细胞的凋亡,并通过减少溴脱氧尿苷(BrdU)、有丝分裂标志物Ki67以及磷酸组蛋白H3(p-Histone-H3)的表达,导致神经元祖细胞的增殖减少。这种物质不仅会干扰小鼠的大脑发育,还会影响其行为。
T2O2774 L-Asparagine

alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine

Endogenous Metabolite Metabolism
L-Asparagine (Asparamide) 是一种非必需氨基酸,可以参与神经和脑组织细胞功能的代谢控制。
TN2252 Syrosingopine

Dopamine Receptor GPCR/G Protein; Neuroscience
Syrosingopine 是 MCT1和 MCT4双重抑制剂,对 MCT4 的效力高 60 倍,可防止乳酸和 H+ 流出。它是可口服抗高血压药物,联合二甲双胍具有研究癌症疾病的潜力。
T4944 Nervonic acid

cis-15-Tetracosenoic acid,神经酸,Selacholeic acid

Endogenous Metabolite Metabolism
Nervonic acid (Selacholeic acid) 是在髓磷脂生物合成中很重要的单不饱和脂肪酸。
T3887 Rosarin

Others Others
Rosarin 是从玫瑰红景天中分离出来的肉桂醇糖苷。它抑制小鼠肾脏和大脑前额皮层中促炎因子 iNOS,IL-1β 和 TNF-α 的表达。它具有抗炎和神经保护作用。
T5S1632 Barlerin

8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01

VEGFR; TNF; NF-κB; Akt; Caspase Angiogenesis; Apoptosis; Cytoskeletal Signaling; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Barlerin (8-O-Acetylshanzhiside methyl ester) 是一种环孢菌素葡萄糖苷,从中国西藏民间药用植物中分离得到,能够抑制NF-κB 活性。
T5684 Ethyl 3,4-dihydroxybenzoate

Apoptosis; Others; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; NO Synthase; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; NF-κB; Others
Ethyl 3,4-dihydroxybenzoate 是从花生种子的种皮中发现的脯氨酰羟化酶抑制剂,是一种抗氧化剂。它是胶原蛋白合成抑制剂,具有骨骼保护作用。它通过激活 NO 合酶并产生线粒体 ROS 来保护心肌,可诱导 ESCC 细胞自噬和凋亡。
T0478 Progesterone

孕酮,Pregn-4-ene-3,20-dione

Estrogen/progestogen Receptor; Progesterone Receptor; Opioid Receptor; Endogenous Metabolite Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience; Others
Progesterone (Pregn-4-ene-3,20-dione) 是类固醇激素,能够调节月经周期。
T2S1720 Huperzine B

AChE Neuroscience
Huperzine B 是一种从 Huperzia serrata 中分离出的石蒜生物碱,也是一种高度选择性的乙酰胆碱酯酶抑制剂,可以用于改善阿尔茨海默氏病。
TN5131 Tetrahydrocannabivarin

THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin

Cannabinoid Receptor GPCR/G Protein
Tetrahydrocannabivarin (CRM) 是 cannabinoid type 1 receptor 的中性拮抗剂,对 2 型糖尿病有潜在治疗价值。
T4439 sn-Glycero-3-phosphocholine

Choline Alfoscerate,甘磷酸胆碱,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC

Endogenous Metabolite; AChE Metabolism; Neuroscience
sn-Glycero-3-phosphocholine (Choline glycerophosphate) 是脑磷脂生物合成的前体,能够提高胆碱在神经组织中的生物利用度。它对认知功能有显著影响,同时具有良好的耐受性和安全性,因此能够用于阿尔茨海默病和痴呆症的研究。
T3414 Morroniside

莫诺苷,奎宁树

Apoptosis; MMP; Pyroptosis Apoptosis; Immunology/Inflammation; Proteases/Proteasome
Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用,可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
TN6953 Lignoceric Acid

二十四烷酸,tetracosanoic acid

Endogenous Metabolite Metabolism
Lignoceric Acid (tetracosanoic acid) 是一种 24 碳饱和 (24:0) 脂肪酸,在发育中的大脑中合成,也是一种木质素生产的副产品。它能够用于研究 Zellweger 脑-肝-肾综合征和肾上腺脑白质营养不良。
T5S0636 Citric acid

柠檬酸,Citro,Citretten

Apoptosis; Others; Endogenous Metabolite; Antibacterial; Antibiotic Apoptosis; Metabolism; Microbiology/Virology; Others
Citric acid (Citro) 是柑橘类水果中发现的弱有机三羧酸。柠檬酸是食品添加剂和天然防腐剂。
T3861 Isobavachalcone

Corylifolinin,Isobacachalcone,补骨脂乙素

Apoptosis; Others; Reactive Oxygen Species; Akt; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Others; PI3K/Akt/mTOR signaling
Isobavachalcone (Corylifolinin) 是来源于补骨脂的一种Akt 信号通路抑制剂,可诱导人类癌细胞凋亡,以IC50值为 7.92 μM 抑制 OVCAR-8 癌细胞生长,具有抗癌和抗增殖活性。它还能诱导 OVCAR-8 细胞中活性氧的产生。
T5287 N-Acetyl-L-aspartic acid

AC-ASP-OH,N-Acetylaspartic acid,N-乙酰-L-天门冬氨酸

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-aspartic acid (AC-ASP-OH) 是天冬氨酸的衍生物, 是由氨基酸天冬氨酸和乙酰辅酶 A 在神经元中合成的。
T4710 3-Methoxytyramine hydrochloride

3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐

Others; Endogenous Metabolite; Drug Metabolite Metabolism; Others
3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) 是多巴胺的无活性代谢物,能够活化痕量胺相关受体1 。
T3836 Eudesmin

MAPK; S6 Kinase MAPK; PI3K/Akt/mTOR signaling
Eudesmin 通过抑制S6K1信号通路来干扰成脂分化,具有抗肿瘤、抗炎和抗菌活性。
T2S1778 DL-Goitrin

DL-甲状腺肿素,板蓝根,Goitrin,(R,S)-告依春

Others Others
DL-Goitrin 也称为 (R,S)-Goitrin,由 epigoitrin (R-Goitrin) 和告依春 (S-Goitrin) 两种异构体组成,是板蓝根的成分。
T0846 L-Carnitine

L(-)-Carnitine,Levocarnitine,左旋肉碱

Endogenous Metabolite; Fatty Acid Synthase Metabolism
L-Carnitine (L(-)-Carnitine) 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A 转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。
T0883 Tramiprosate

Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸

Beta Amyloid; GABA Receptor Membrane transporter/Ion channel; Neuroscience
Tramiprosate (Alzhemed) 是一种具有口服活性的、可透过血脑屏障的天然氨基酸,存在于各种红色海藻中,能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物,具有神经保护,抗惊厥和抗高血压的活性。
T3S1729 Dihydrolycorine

Others Others
Dihydrolycorine 是分离自Lycoris radiate 草药中,是一种真核细胞中蛋白质合成的抑制剂。
T13979 (S)-3-Hydroxybutanoic acid

L-β-Hydroxybutyric acid,(S)-β-Hydroxybutanoic acid,L-(+)-3-Hydroxybutyric acid,(S)-3-羟基丁酸

Endogenous Metabolite Metabolism
(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) 是一种正常的人体代谢产物,在患有抑郁症的老年患者中升高。它在人类的肝脏中由乙酰-CoA 合成,当血糖低时能够被脑用作能量来源。
T4947 3-Hydroxybutyric acid

Butanoic acid,3-羟基丁酸

Endogenous Metabolite Metabolism
3-Hydroxybutyric acid (Butanoic acid) 是一种人内源性代谢物,在 I 型糖尿病中升高。它能够调节膜脂的性质。
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天然产物

L(+)-Asparagine monohydrate
Cat.No: T8392
Synonym:
Target: Endogenous Metabolite
Rutin
Cat.No: T0795
Synonym: Quercetin 3-O-rutinoside,芦丁,Rutoside
Target: Beta Amyloid, Prostaglandin Receptor, Autophagy
Physostigmine Salicylate
Cat.No: T0130
Synonym: 水杨酸依色林,水杨酸毒扁豆碱
Target: AChR, AChE
Paederosidic acid methyl ester
Cat.No: T3S0870
Synonym: 鸡屎藤苷酸甲酯,紫草酸甲酯
Target: ATPase, Potassium Channel, NO Synthase
Dimethyl fumarate
Cat.No: T0492
Synonym: 富马酸二甲酯,DMF
Target: Reactive Oxygen Species, HIV Protease, Nrf2, Endogenous Metabolite, Autophagy
L-DOPA
Cat.No: T0848
Synonym: 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine
Target: Dopamine Receptor, Endogenous Metabolite
Rutin hydrate
Cat.No: T22417
Synonym: 芦丁,Rutoside,Sophorin,Quercetin-3-O-rutinoside
Target: Beta Amyloid, Others, Autophagy
Premarin
Cat.No: T36857L
Synonym: 共轭雌激素,Estrone 3-sulfate,Estrone sulfate
Target: Estrogen Receptor/ERR
4-Methylcatechol
Cat.No: T4779
Synonym: p-Methylcatechol,3,4-二羟基甲苯,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene
Target: Others, Endogenous Metabolite
Spaglumic acid
Cat.No: TQ0285
Synonym: 异冬谷酸,N-Acetylaspartylglutamic acid,NAAG
Target: Endogenous Metabolite
D-N-Acetylgalactosamine
Cat.No: T4708
Synonym: D-GalNAc,N-Acetyl-D-galactosamine,N-乙酰-D-半乳糖胺
Target: Others, Endogenous Metabolite
Paederosidic acid
Cat.No: T5739
Synonym: 鸡屎藤苷酸,异戊二酸 紫草酸
Target: Apoptosis, BCL
Galanthamine
Cat.No: T4S1725
Synonym: Galantamine,加兰他敏
Target: Apoptosis, AChE
3-demethylcolchicine
Cat.No: TN6706
Synonym: 3-去甲秋水仙碱,3-去甲基秋水仙碱
Target: Reactive Oxygen Species
Docosahexaenoic Acid
Cat.No: T5369
Synonym: Cervonic acid,DHA
Target: Others, Endogenous Metabolite
Phosphorylethanolamine
Cat.No: T4881
Synonym: O-Phosphorylethanolamine,乙醇胺磷酸酯
Target: Others, Endogenous Metabolite
Parishin
Cat.No: T4S1820
Synonym: 巴利森苷A,派立辛,Parishin A
Target: Others
Creatine monohydrate
Cat.No: T22300
Synonym: Methylguanidoacetic acid monohydrate,一水肌酸
Target: Others, Endogenous Metabolite
Taxol C
Cat.No: TN5118
Synonym:
Target: P-gp
Marizomib
Cat.No: T16012
Synonym: NPI-0052,Salinosporamide A,ML858
Target: Proteasome
Salvianolic acid A
Cat.No: T6S0444
Synonym: 丹酚酸 A,Dan Phenolic Acid A
Target: MMP
L-Carnosine
Cat.No: T4732
Synonym: Karnozin,L-肌肽,beta-Alanyl-L-histidine
Target: Antioxidant, Endogenous Metabolite
2-(4-Methoxyphenyl)acetic acid
Cat.No: T5590
Synonym: 4-Methoxyphenylacetic acid,对甲氧基苯乙酸
Target: Others, Endogenous Metabolite
Dauricine
Cat.No: T6S0119
Synonym: 蝙蝠葛碱
Target: Apoptosis, Others, NF-κB
Phosphocreatine disodium
Cat.No: T3262
Synonym: Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt,磷酸肌酸钠
Target: Others, Endogenous Metabolite
Cytosporone B
Cat.No: T3976
Synonym: Csn-B,Dothiorelone G
Target: Others
4-tert-Octylphenol
Cat.No: T64353
Synonym:
Target: Endogenous Metabolite
L-Asparagine
Cat.No: T2O2774
Synonym: alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine
Target: Endogenous Metabolite
Syrosingopine
Cat.No: TN2252
Synonym:
Target: Dopamine Receptor
Nervonic acid
Cat.No: T4944
Synonym: cis-15-Tetracosenoic acid,神经酸,Selacholeic acid
Target: Endogenous Metabolite
Rosarin
Cat.No: T3887
Synonym:
Target: Others
Barlerin
Cat.No: T5S1632
Synonym: 8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01
Target: VEGFR, TNF, NF-κB, Akt, Caspase
Ethyl 3,4-dihydroxybenzoate
Cat.No: T5684
Synonym:
Target: Apoptosis, Others, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, NO Synthase, Autophagy
Progesterone
Cat.No: T0478
Synonym: 孕酮,Pregn-4-ene-3,20-dione
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Opioid Receptor, Endogenous Metabolite
Huperzine B
Cat.No: T2S1720
Synonym:
Target: AChE
Tetrahydrocannabivarin
Cat.No: TN5131
Synonym: THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin
Target: Cannabinoid Receptor
sn-Glycero-3-phosphocholine
Cat.No: T4439
Synonym: Choline Alfoscerate,甘磷酸胆碱,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC
Target: Endogenous Metabolite, AChE
Morroniside
Cat.No: T3414
Synonym: 莫诺苷,奎宁树
Target: Apoptosis, MMP, Pyroptosis
Lignoceric Acid
Cat.No: TN6953
Synonym: 二十四烷酸,tetracosanoic acid
Target: Endogenous Metabolite
Citric acid
Cat.No: T5S0636
Synonym: 柠檬酸,Citro,Citretten
Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic
Isobavachalcone
Cat.No: T3861
Synonym: Corylifolinin,Isobacachalcone,补骨脂乙素
Target: Apoptosis, Others, Reactive Oxygen Species, Akt, Autophagy
N-Acetyl-L-aspartic acid
Cat.No: T5287
Synonym: AC-ASP-OH,N-Acetylaspartic acid,N-乙酰-L-天门冬氨酸
Target: Others, Endogenous Metabolite
3-Methoxytyramine hydrochloride
Cat.No: T4710
Synonym: 3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐
Target: Others, Endogenous Metabolite, Drug Metabolite
Eudesmin
Cat.No: T3836
Synonym:
Target: MAPK, S6 Kinase
DL-Goitrin
Cat.No: T2S1778
Synonym: DL-甲状腺肿素,板蓝根,Goitrin,(R,S)-告依春
Target: Others
L-Carnitine
Cat.No: T0846
Synonym: L(-)-Carnitine,Levocarnitine,左旋肉碱
Target: Endogenous Metabolite, Fatty Acid Synthase
Tramiprosate
Cat.No: T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸
Target: Beta Amyloid, GABA Receptor
Dihydrolycorine
Cat.No: T3S1729
Synonym:
Target: Others
(S)-3-Hydroxybutanoic acid
Cat.No: T13979
Synonym: L-β-Hydroxybutyric acid,(S)-β-Hydroxybutanoic acid,L-(+)-3-Hydroxybutyric acid,(S)-3-羟基丁酸
Target: Endogenous Metabolite
3-Hydroxybutyric acid
Cat.No: T4947
Synonym: Butanoic acid,3-羟基丁酸
Target: Endogenous Metabolite
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Cat. No. Product Name Species Expression System
TMPY-05510 BDNF Protein, Mouse, Recombinant (His)

brain-derived neurotrophic factor

Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPJ-00135 BDNF Protein, Human/Murine/Rat, Recombinant

BDNF,Abrineurin,Brain-Derived Neurotrophic Factor

Human,Mouse,Rat E. coli
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. ...
TMPY-04699 GAD65 Protein, Human, Recombinant (GST)

glutamate decarboxylase 2 (pancreatic islets and brain

Human Baculovirus Insect Cells
GAD65 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 92.6 kDa and the accession number is Q05329.
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPY-03120 Prostaglandin D2 Synthase Protein, Human, Recombinant (His)

PDS,L-PGDS,PGDS,PGDS2,LPGDS,PGD2,prostaglandin D2 synthase 2...

Human HEK293 Cells
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222.
TMPY-05069 Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)

prostaglandin D2 synthase 21kDa (brain)

Rat HEK293 Cells
Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A6JT70.
TMPJ-00875 NPPB Protein, Human, Recombinant (His)

NPPB,γ-Brain Natriuretic Peptide,Gamma-Brain

Human E. coli
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.
TMPJ-00874 NT-proBNP Protein, Human, Recombinant (His & Flag)

γ-brain natriuretic peptide,Gamma-brain na...

Human E. coli
Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP), a useful marker of heart failure (HF), is considered to be secreted mainly from the ventricle, increased serum NT-proBNP levels are also encountered in conditions such ...
TMPY-03430 RheB Protein, Human, Recombinant (His)

Ras homolog enriched in brain,RHEB2

Human Baculovirus Insect Cells
RHEB is a recently discovered member of the Ras superfamily that may be involved in neural plasticity. This function is novel and not typically associated with the Ras proteins. RHEB gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. RHEB is vital in regulation of growth and cell cycle progression due to its role in the insulin / TOR / S6K signaling pathway. The protein has GTPase activity ...
TMPJ-00134 pro-BDNF Protein, Human, Recombinant

Brain-Derived Neurotrophic Factor,Abrineurin,BDNF

Human E. coli
The precursor form of Brain-Derived Neurotrophic Factor (pro-BDNF) interacts preferentially with the pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin and induces neuronal apoptosis, whereas mature BDNF selectively binds with high affinity to the TrkB kinase receptor and promotes the survival, growth and differentiation of neurons. As proneurotrophins and mature neurotrophins elicit opposite biological effects, Pro-BDNF cleavage in the neuronal system is regul...
TMPH-03251 BDNF Protein, Rat, Recombinant (His)

Brain-derived neurotrophic factor,BDNF

Rat E. coli
BDNF Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is P23363.
TMPJ-00671 FABP7 Protein, Human, Recombinant (His)

Fatty Acid-Binding Protein 7,Mammary-Derived Growth Inhibito...

Human E. coli
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP7 is predominately expressed in brain and neural tissues. FABP7 is involved in fatty acid uptake and intracellular transport and is important in brain development. FABP7 plays a critical role in the transport of a so far unknow...
TMPY-02091 GAD67 Protein, Human, Recombinant (His)

SCP,CPSQ1,glutamate decarboxylase 1 (brain, 67kDa),...

Human Baculovirus Insect Cells
Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of thegroup II decarboxylase family. GAD1 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker. GAD1 isoform3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. Tissue-specific markers are useful for identification of tumour type ...
TMPJ-00685 BAI3 Protein, Human, Recombinant (His)

BAI3,KIAA0550,Brain-Specific Angiogenesis Inhibitor...

Human HEK293 Cells
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-...
TMPH-03253 BCAN Protein, Rat, Recombinant (His & Myc)

Brevican core protein,Behab,Bcan,Brain-enriched hya...

Rat Baculovirus Insect Cells
May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Isoform 2 may function as a chondroitin sulfate-bearing cell surface receptor. BCAN Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 19 kDa and the accession number is P55068.
TMPK-01088 PODXL2 Protein, Mouse, Recombinant (His)

UNQ1861/PRO3742,oct-8,PODLX2,OTF8,Endoglycan,BRN1,EG,bra...

Mouse HEK293 Cells
Transmembrane protein endoglycan (PODXL2), which belongs to the CD34-family of highly glycosylated sialomucins. Endoglycan is broadly expressed in the developing mouse brains and is proteolytically shed in vitro in mouse neurons and in vivo in mouse brains. Endoglycan shedding in primary neurons was mediated by the transmembrane protease a disintegrin and metalloprotease 10 (ADAM10), but not by its homolog ADAM17. PODXL2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells wi...
TMPH-01035 CNR1 Protein-VLP, Human, Recombinant (His)

Cnr1,Skr6,CB1,CB-R,Cannabinoid receptor 1,Brain-typ...

Human HEK293 Cells
CNR1 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 54.6 kDa and the accession number is P21554.
TMPH-03252 BCAN Protein, Rat, Recombinant (hFc)

Bcan,Behab,BEHAB,Brevican core protein,Brain-enrich...

Rat HEK293 Cells
May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans. Isoform 2 may function as a chondroitin sulfate-bearing cell surface receptor. BCAN Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFC tag. The predicted molecular weight is 44 kDa and the accession number is P55068.
TMPK-01213 PODXL2 Protein, Human, Recombinant (His)

BRN1,oct-8,UNQ1861/PRO3742,brain-1,EG,Endoglycan,PO...

Human HEK293 Cells
Transmembrane protein endoglycan (PODXL2), which belongs to the CD34-family of highly glycosylated sialomucins. Endoglycan is broadly expressed in the developing mouse brains and is proteolytically shed in vitro in mouse neurons and in vivo in mouse brains. Endoglycan shedding in primary neurons was mediated by the transmembrane protease a disintegrin and metalloprotease 10 (ADAM10), but not by its homolog ADAM17. PODXL2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells wi...
TMPY-04761 Creatine kinase B Protein, Human, Recombinant (His)

HEL-S-29,CKBB,HEL-211,creatine kinase, brain,BCK,B-...

Human Baculovirus Insect Cells
CKB(Creatine kinase B type) contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. It belongs to the ATP:guanido phosphotransferase family. CKB consists of a homodimer of two identical brain-type CK-B subunits. CKB is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CKB forms tightly coupled microcompartments ...
TMPJ-01126 RheB Protein, Human, Recombinant (GST)

RHEB,Ras Homolog Enriched in Brain,GTP-Binding Prot...

Human E. coli
GTP-Binding Protein Rheb (RHEB) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. Highest levels of RHEB can be found in the skeletal and cardiac muscle, and it is vital in the regulation of growth and cell cycle progression due to its role in the Insulin/TOR/S6K signaling pathway. RHEB stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling, and it activates...
TMPY-03515 GAD65 Protein, Mouse, Recombinant

glutamate decarboxylase 2 (pancreatic islets and brain

Mouse Baculovirus Insect Cells
GAD65 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 65.4 kDa and the accession number is P48320.
TMPJ-00818 ALDOC Protein, Human, Recombinant (His)

Aldolase C,ALDC,zebrin II,Aldo3,Scrg2,Fructose-bisphosphate ...

Human HEK293 Cells
Fructose-bisphosphate aldolase C (ALDOC) belongs to the class I fructose-bisphosphate aldolase family. It is an enzyme that, in humans, is encoded by the ALDOC gene. ALDOC is expressed exclusively in the hippocampus and Purkinje cells of the brain. ALDOC is a glycolytic enzyme which catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehydes respectively
TMPH-03256 CNR1 Protein, Rat, Recombinant (His)

Skr6,Brain-type cannabinoid receptor,Cannabinoid re...

Rat E. coli
CNR1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 58.9 kDa and the accession number is P20272.
TMPY-03276 BLBP Protein, Human, Recombinant

fatty acid binding protein 7, brain,FABPB,MRG,B-FAB...

Human E. coli
BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expre...
TMPY-04624 Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)

Ptgs3,L-PGDS,prostaglandin D2 synthase 21kDa (brain...

Mouse HEK293 Cells
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is O09114-1.
TMPJ-00491 BCAN Protein, Human, Recombinant (His)

Chondroitin Sulfate Proteoglycan 7,BCAN,CSPG7,BEHAB,Brai...

Human HEK293 Cells
Brevican Core Protein (BCAN) is a secreted protein that belongs to the aggrecan/versican proteoglycan family. BCAN contains one C-type lectin domain, one EGF-like domain, one Ig-like V-type domain, one Sushi (CCP/SCR) domain and two Link domains. BCAN may play a role in the terminally differentiating and the adult nervous system during postnatal development. BCAN could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
TMPY-01590 GAD65 Protein, Mouse, Recombinant (His & GST)

glutamate decarboxylase 2 (pancreatic islets and brain

Mouse Baculovirus Insect Cells
GAD65 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 93 kDa and the accession number is P48320.
TMPJ-00695 CuTA Protein, Human, Recombinant (His)

C6orf82,Brain Acetylcholinesterase Putative Membran...

Human E. coli
Protein CutA (CUTA) posseses a signal peptide and is widely expressed in brain. CUTA mayforms part of a complex of membrane proteins attached to acetylcholinesterase (AChE). CUTA takes part in cellular tolerance to a broad range of divalent cations other than copper. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found.
TMPH-02665 Aldolase C Protein, Mouse, Recombinant (His & Myc)

Aldolase 3,Brain-type aldolase,Aldo3,Scrg2,Scrapie-...

Mouse E. coli
Aldolase C Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 46.7 kDa. Accession number: P05063
TMPJ-01296 SULT4A1 Protein, Human, Recombinant

hBR-STL,SULTX3,Nervous System Sulfotransferase,SULT4A1,ST4A1...

Human E. coli
Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family. ST4A1 is highly expressed in the cerebral cortex and frontal lobe, but no expression is detected in the pancreas. ST4A1 is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. ST4A1 acts on catecholamines and T4 in a manner that may not involve sulfonation. ST4A1 may have a role in the metabolism of drugs and neurotransmitters in the CNS. In addition, ST4A1 is related to schizo...
TMPJ-01320 BSSP-4 Protein, Human, Recombinant (His)

BSSP4,Tryptase ε,Serine Protease 26,BSSP-4,Serine Protease 2...

Human HEK293 Cells
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after a...
TMPH-02664 Aldolase C Protein, Mouse, Recombinant (His)

Aldo3,Brain-type aldolase,Zebrin II,Fructose-bispho...

Mouse P. pastoris (Yeast)
Aldolase C Protein, Mouse, Recombinant (His) is expressed in Yeast.
TMPH-02553 BSSP-4 Protein, Mouse, Recombinant (His)

Serine protease 26,Brain-specific serine protease 4...

Mouse E. coli
N/A. BSSP-4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is Q9ER10.
TMPJ-01051 Pleiotrophin/PTN Protein, Mouse, Recombinant (His)

HBGF-8,OSF-1,PTN,HBBM,Pleiotrophin,Heparin-binding brain...

Mouse HEK293 Cells
Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein,Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates it...
TMPJ-00962 AKR1C3 Protein, Human, Recombinant (His)

3-Alpha-HSD Type 2,17-β-Hydroxysteroid Dehydrogenase Type 5,...

Human HEK293 Cells
AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and ...
TMPJ-00306 SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated

Brain Ig-Like Molecule with Tyrosine-Based Activati...

Human HEK293 Cells
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ...
TMPJ-01183 SIRP alpha Protein, Mouse, Recombinant (aa 32-373, His)

CD172 Antigen-Like Family Member A,Macrophage Fusion Recepto...

Mouse HEK293 Cells
SIRP alpha Protein, Mouse, Recombinant (aa 32-373, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 60-110 KDa and the accession number is Q6P6I8.
TMPJ-00305 SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)

Inhibitory Feceptor SHPS-1,MyD-1 Antig,Brain Ig-Lik...

Cynomolgus HEK293 Cells
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ...
TMPY-03104 FGF-17 Protein, Human, Recombinant

fibroblast growth factor 17,HH20,FGF-13,FGF-17

Human E. coli
FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-13 is preferentially expressed in the embryonic brain. It interacts with FGFR3 and FGFR4. FGF-13 plays an important role in the regulation of embryonic development and as signaling mol...
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-01897 PRSS3 Protein, Human, Recombinant (His)

PRSS4,TRY4,TRY3,RP11-176F3.3,T9,MTG,protease, serine 3

Human HEK293 Cells
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPJ-00842 FGF-2 Protein, Rat, Recombinant

bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblast Growth ...

Rat E. coli
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g...
TMPJ-00090 FGF-9 Protein, Human, Recombinant

Fibroblast Growth Factor 9,Heparin-Binding Growth Factor 9,F...

Human E. coli
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In addition, FGF-9 may have a role in glial c...
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant

NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3

Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ...
TMPY-02292 IGSF11 Protein, Human, Recombinant (His)

CT119,immunoglobulin superfamily, member 11,BT-IgSF,Igsf13,C...

Human HEK293 Cells
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to overexpressed in colorectal cancers and hep...
TMPJ-01469 NGF Protein, Human, Recombinant (E. colli)

NGFB,神经生长因子,β-NGF,NGF,Beta-Nerve Growth Factor,β-Nerve Growt...

Mouse E. coli
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an impo...
TMPY-03425 Tau Protein, Human, Recombinant (His)

PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ...

Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPY-02956 Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)

APOL1,apolipoprotein L1,APOL,FSGS4,APOL-I,APO-L

Human Baculovirus Insect Cells
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney, and brain. APOL1 belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. It may also participate in reverse cholesterol transport from peripheral cells to the liver. Defects in APOL1 are the cause of focal segmental glomer...
TMPY-01355 Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)

G-α-h,HEL-S-45,TGC,transglutaminase 2,TG2,GNAH,G-ALPHA-h

Human Baculovirus Insect Cells
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which...
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重组蛋白

BDNF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05510
Species: Mouse
Expression System: HEK293 Cells
BDNF Protein, Human/Murine/Rat, Recombinant
Cat.No: TMPJ-00135
Species: Human,Mouse,Rat
Expression System: E. coli
GAD65 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04699
Species: Human
Expression System: Baculovirus Insect Cells
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
Prostaglandin D2 Synthase Protein, Human, Recombinant (His)
Cat.No: TMPY-03120
Species: Human
Expression System: HEK293 Cells
Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)
Cat.No: TMPY-05069
Species: Rat
Expression System: HEK293 Cells
NPPB Protein, Human, Recombinant (His)
Cat.No: TMPJ-00875
Species: Human
Expression System: E. coli
NT-proBNP Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00874
Species: Human
Expression System: E. coli
RheB Protein, Human, Recombinant (His)
Cat.No: TMPY-03430
Species: Human
Expression System: Baculovirus Insect Cells
pro-BDNF Protein, Human, Recombinant
Cat.No: TMPJ-00134
Species: Human
Expression System: E. coli
BDNF Protein, Rat, Recombinant (His)
Cat.No: TMPH-03251
Species: Rat
Expression System: E. coli
FABP7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00671
Species: Human
Expression System: E. coli
GAD67 Protein, Human, Recombinant (His)
Cat.No: TMPY-02091
Species: Human
Expression System: Baculovirus Insect Cells
BAI3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00685
Species: Human
Expression System: HEK293 Cells
BCAN Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03253
Species: Rat
Expression System: Baculovirus Insect Cells
PODXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01088
Species: Mouse
Expression System: HEK293 Cells
CNR1 Protein-VLP, Human, Recombinant (His)
Cat.No: TMPH-01035
Species: Human
Expression System: HEK293 Cells
BCAN Protein, Rat, Recombinant (hFc)
Cat.No: TMPH-03252
Species: Rat
Expression System: HEK293 Cells
PODXL2 Protein, Human, Recombinant (His)
Cat.No: TMPK-01213
Species: Human
Expression System: HEK293 Cells
Creatine kinase B Protein, Human, Recombinant (His)
Cat.No: TMPY-04761
Species: Human
Expression System: Baculovirus Insect Cells
RheB Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01126
Species: Human
Expression System: E. coli
GAD65 Protein, Mouse, Recombinant
Cat.No: TMPY-03515
Species: Mouse
Expression System: Baculovirus Insect Cells
ALDOC Protein, Human, Recombinant (His)
Cat.No: TMPJ-00818
Species: Human
Expression System: HEK293 Cells
CNR1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03256
Species: Rat
Expression System: E. coli
BLBP Protein, Human, Recombinant
Cat.No: TMPY-03276
Species: Human
Expression System: E. coli
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04624
Species: Mouse
Expression System: HEK293 Cells
BCAN Protein, Human, Recombinant (His)
Cat.No: TMPJ-00491
Species: Human
Expression System: HEK293 Cells
GAD65 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-01590
Species: Mouse
Expression System: Baculovirus Insect Cells
CuTA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00695
Species: Human
Expression System: E. coli
Aldolase C Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02665
Species: Mouse
Expression System: E. coli
SULT4A1 Protein, Human, Recombinant
Cat.No: TMPJ-01296
Species: Human
Expression System: E. coli
BSSP-4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01320
Species: Human
Expression System: HEK293 Cells
Aldolase C Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02664
Species: Mouse
Expression System: P. pastoris (Yeast)
BSSP-4 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02553
Species: Mouse
Expression System: E. coli
Pleiotrophin/PTN Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01051
Species: Mouse
Expression System: HEK293 Cells
AKR1C3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00962
Species: Human
Expression System: HEK293 Cells
SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00306
Species: Human
Expression System: HEK293 Cells
SIRP alpha Protein, Mouse, Recombinant (aa 32-373, His)
Cat.No: TMPJ-01183
Species: Mouse
Expression System: HEK293 Cells
SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)
Cat.No: TMPJ-00305
Species: Cynomolgus
Expression System: HEK293 Cells
FGF-17 Protein, Human, Recombinant
Cat.No: TMPY-03104
Species: Human
Expression System: E. coli
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
PRSS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01897
Species: Human
Expression System: HEK293 Cells
FGF-2 Protein, Rat, Recombinant
Cat.No: TMPJ-00842
Species: Rat
Expression System: E. coli
FGF-9 Protein, Human, Recombinant
Cat.No: TMPJ-00090
Species: Human
Expression System: E. coli
Neurotrophin 3 Protein, Human, Recombinant
Cat.No: TMPY-04069
Species: Human
Expression System: E. coli
IGSF11 Protein, Human, Recombinant (His)
Cat.No: TMPY-02292
Species: Human
Expression System: HEK293 Cells
NGF Protein, Human, Recombinant (E. colli)
Cat.No: TMPJ-01469
Species: Mouse
Expression System: E. coli
Tau Protein, Human, Recombinant (His)
Cat.No: TMPY-03425
Species: Human
Expression System: E. coli
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02956
Species: Human
Expression System: Baculovirus Insect Cells
Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01355
Species: Human
Expression System: Baculovirus Insect Cells
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