CMX-8933 is an 8-peptide fragment of the goldfish brain neurotrophic ependymin protein. This compound enhances the enzymatic activity of c-Jun N-terminal kinase (JNK), promotes the phosphorylation of JNK and c-Jun proteins, and increases the cellular levels of c-Jun and c-Fos mRNA. CMX-8933 is utilized for investigating the role of ependymin proteins in neural plasticity, learning, memory formation, and neural regeneration.