Name: Phoenixin-14 TFA
Brand: TargetMol
SKU: T81485
Price: 598 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 598

In stock

5 mg

¥ 1,325

In stock

10 mg

¥ 1,990

In stock

25 mg

¥ 3,380

In stock

50 mg

¥ 5,070

In stock

产品介绍

生物活性

产品描述	Phoenixin-14 TFA (PNX-14 TFA) is an endogenous neuropeptide present in the central nervous system, circulation, and peripheral tissues. It regulates appetite, pain perception, and reproductive system neurons, stimulates insulin secretion, enhances memory, and provides cardiac and neural protection. It modulates GnRH receptor expression and exerts anxiolytic effects.
体外活性	方法：Phoenixin-14（1–1000 nM）处理黄体细胞，将细胞储存在-70 °C以分析STAR、CYP11A1、HSD3B、CYP19A1、PTGER2和PTGFR mRNA和蛋白水平以及LH受体（LHCGR）蛋白表达。结果：Phoenixin-14增加了 STAR、CYP11A1、HSD3B 和 CYP19A1 mRNA 水平，1和10 nM的Phoenixin-14增加HSD3B表达，100和1000 nM的Phoenixin-14增加STAR和CYP19A1表达，而所有剂量的Phoenixin-14均增加CYP11A1表达。[2]
体内活性	Phoenixin-14（50 μg/kg，腹腔注射，每天，7天）处理SCI小鼠模型，可以改善SCI损伤小鼠的运动功能。[3]
别名	PNX-14 TFA

化学信息

分子量	1583.78 (free base)
分子式	C₇₅H₁₁₀N₁₈O₂₀.xC₂HF₃O₂
Smiles	[H]N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N2CCC[C@H]2C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@H](C(N[C@@H](CC(O)=O)C(N5CCC[C@H]5C(N[C@@H](CC6=CC=CC=C6)C(N)=O)=O)=O)=O)CO)=O)=O)C(C)C)=O)CCCCN)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)C(C)C)=O.OC(C(F)(F)F)=O
Sequence	Asp-Val-Gln-Pro-Pro-Gly-Leu-Lys-Val-Trp-Ser-Asp-Pro-Phe-NH2
Sequence Short	DVQPPGLKVWSDPF-NH2

储存&溶解度

存储	keep away from moisture,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	DMSO: 100 mg/mL, Sonication is recommended.

体内实验配液计算器