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顶部相关产品产品介绍化学信息储存和溶解信息计算器

(±)7(8)-EpDPA

货号 T35497Cas号 895127-66-9 一键复制产品信息
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Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting vasodilation, inhibiting angiogenesis, and decreasing inflammatory and neuropathic pain. (±)7(8)-EpDPA is a substrate of soluble epoxide hydrolase (KM = 15 μM), which converts it to the corresponding diol.

(±)7(8)-EpDPA

一键复制产品信息
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货号 T35497Cas号 895127-66-9

Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting vasodilation, inhibiting angiogenesis, and decreasing inflammatory and neuropathic pain. (±)7(8)-EpDPA is a substrate of soluble epoxide hydrolase (KM = 15 μM), which converts it to the corresponding diol.

(±)7(8)-EpDPA
其他形式的 “(±)7(8)-EpDPA”:
(±)10(11)-EpDPA
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规格价格库存数量
25 μg
¥ 987
35日内发货
50 μg
¥ 1,970
35日内发货
100 μg
¥ 3,660
35日内发货
500 μg
¥ 16,200
35日内发货
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产品介绍

生物活性
产品描述
Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and is increased following dietary supplementation with ω-3 fatty acids. (±)7(8)-EpDPA and other epoxy metabolites of DHA modulate receptor and channel activities to evoke diverse effects, such as promoting vasodilation, inhibiting angiogenesis, and decreasing inflammatory and neuropathic pain. (±)7(8)-EpDPA is a substrate of soluble epoxide hydrolase (KM = 15 μM), which converts it to the corresponding diol.
化学信息
分子量344.495
分子式C22H32O3
CAS No.895127-66-9
SmilesCC\C=C/C\C=C/C\C=C/C\C=C/CC1OC1C\C=C/CCC(O)=O
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息
PBS (pH 7.2): 1 mg/mL (2.9 mM), Sonication is recommended.
DMSO: 50 mg/mL (145.14 mM), Sonication is recommended.
Ethanol: 50 mg/mL (145.14 mM), Sonication is recommended.
DMF: 50 mg/mL (145.14 mM), Sonication is recommended.
溶液配制表
PBS (pH 7.2)/DMSO/Ethanol/DMF
1mg5mg10mg50mg
1 mM2.9028 mL14.5140 mL29.0280 mL145.1400 mL
DMSO/Ethanol/DMF
1mg5mg10mg50mg
5 mM0.5806 mL2.9028 mL5.8056 mL29.0280 mL
10 mM0.2903 mL1.4514 mL2.9028 mL14.5140 mL
20 mM0.1451 mL0.7257 mL1.4514 mL7.2570 mL
50 mM0.0581 mL0.2903 mL0.5806 mL2.9028 mL
100 mM0.0290 mL0.1451 mL0.2903 mL1.4514 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

7(8)-EpDPA(±)7(8)EpDPA(±)7(8) EpDPA
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