|
TMPJ-01321
|
MAP1LC3B Protein, Human, Recombinant
Autophagy-related ubiquitin-like modifier LC3 B,MAP1A/MAP1B ...
|
Human
|
E. coli
|
|
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in the MAP1LC3 subfamily (others include MAP1LC3A, MAP1LC3C, and MAP1LC3B2). It is moat abundantly expressed in heart, brain, skeletal muscle and testis. LMAP1LC3B is a subunit of neuronal microtubule and functions in formation of autophagosomal vacuoles (autophagosomes). It associat... |
|
TMPY-03256
|
NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)
KLR,killer cell lectin-like receptor subfamily K, member 1,D...
|
Human
|
Baculovirus-Insect Cells
|
|
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stim... |
|
TMPY-03376
|
NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His)
NKG2-D,NKG2D,KLRK1,killer cell lectin-like receptor subfamil...
|
Rhesus
|
Baculovirus-Insect Cells
|
|
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stim... |
|
TMPY-03650
|
BirA Protein, E. coli, Recombinant (His & MBP)
BirA,dhbB,bioR
|
E. coli
|
E. coli
|
|
The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these proteins to be tetramerized by binding to streptavidin. Because of the specificity of the biotinylation at the C terminus, the orientation of the membrane proteins on the streptavidin is equivalent to that of the native protein on the cell surface. These tetrameric proteins can be use... |
|
TMPY-05414
|
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
D6H12S2489E,NKG2-D,killer cell lectin-like receptor subfamil...
|
Mouse
|
Baculovirus-Insect Cells
|
|
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stim... |
|
TMPY-00467
|
NKG2D/CD314 Protein, Human, Recombinant (hFc)
D12S2489E,killer cell lectin-like receptor subfamily K, memb...
|
Human
|
CHO
|
|
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stim... |
|
TMPY-03425
|
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ...
|
Human
|
E. coli
|
|
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... |
|
TMPY-02443
|
HSP70 Protein, Human, Recombinant (His)
heat shock 70kDa protein 1A,HSP70-1,HSP70I,HSP70-1A,HEL-S-10...
|
Human
|
Baculovirus-Insect Cells
|
|
HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. HSP are abundant and conserved proteins present in all cells. Upon temperature shock or other stress stimuli, HSP is synthesized intracellularly, which may protect cells from protein denaturation or death. Extracellularly, HSP can serve a cytokine function to initiate both innate and adaptive immunity through activation of APC. HSP serves also... |
|
TMPJ-00745
|
IFN-alpha 2a/IFNA2 Protein, Human, Recombinant
Interferon α-2,IFNA2,干扰素,IFN α2a,IFN-α-2,IFN-Alpha-2,Interfe...
|
Human
|
E. coli
|
|
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-ter... |
|
TMPJ-00746
|
IFN-alpha 2b/IFNA2 Protein, Human, Recombinant
干扰素,IFNA2,Interferon α-2,Interferon α-A,Interferon Alpha-2,I...
|
Human
|
E. coli
|
|
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the ca... |
|
TMPH-03765
|
Virus-Like Particles (VLPs) isotype control
|
|
HEK293
|
|
Virus-Like Particles (VLPs) isotype control can be used as the control of VLP expressed proteins. |
|
TMPY-00541
|
LON PROTEASE Protein, E. coli, Recombinant (His)
|
E. coli
|
E. coli
|
|
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and naturally short-lived proteins, ATPase and chaperone-like activities, as well as DNA binding. Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix and degrades oxidized and misfolded proteins, th... |
|
TMPY-02953
|
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
ATR,TEM8,anthrax toxin receptor 1,GAPO
|
Human
|
HEK293
|
|
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro... |
|
TMPY-01478
|
HSP90 alpha Protein, Human, Recombinant
Hsp89,Hsp90,HSPCAL1,heat shock protein 90kDa alpha (cytosoli...
|
Human
|
E. coli
|
|
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoeostatic control mechanisms. HSP90 interacts with 'client proteins', including protein kinases, transcription factors, and others, and either facilitates their stabilization and activation or directs them for proteasomal degradation. By this means, HSP90 displays a multifaceted ab... |
|
TMPY-06058
|
Influenza A H3N2 (A/Hong Kong/2671/2019) Nucleoprotein/NP Protein (His)
NP Protein
|
H3N2
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-06061
|
Influenza B (B/Washington/02/2019) Nucleoprotein/NP Protein (His)
Nucleoprotein,NP Protein
|
Influenza B
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-02617
|
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His)
NP Protein
|
H2N2
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-03441
|
SAE1 Protein, Human, Recombinant
SUA1,SUMO1 activating enzyme subunit 1,HSPC140,UBLE1A,AOS1
|
Human
|
Baculovirus-Insect Cells
|
|
SAE1 belongs to the ubiquitin-activating E1 family. It is a heterodimer that acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It functions as a UBLI E1 ligase mediating the ATP-dependent activation of UBL1. SAE1 binds with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1. SAE1 also regulates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activati... |
|
TMPY-02876
|
Influenza A H1N1 (A/California/07/2009) Nucleoprotein/NP Protein (His)
NP Protein
|
H1N1
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-03955
|
Influenza A H7N9 (A/Shanghai/2/2013) Nucleoprotein/NP Protein (His)
NP Protein, H7N9
|
H7N9
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-06059
|
Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019) Nucleoprotein/NP Protein (His)
NP Protein
|
H1N1
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-01382
|
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein/NP Protein (I116M, His)
NP Protein
|
H1N1
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-04688
|
Influenza B (B/Florida/4/2006) Nucleoprotein/NP Protein (His)
NP Protein,Nucleoprotein
|
Influenza B
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-00560
|
Influenza A H3N2 (A/Aichi/2/1968) Nucleoprotein/NP Protein (His)
NP Protein
|
H3N2
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-06062
|
Influenza B (B/Phuket/3073/2013) Nucleoprotein/NP Protein (His)
NP Protein,Nucleoprotein
|
Influenza B
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-06060
|
Influenza A H1N1 (A/Hawaii/70/2019) Nucleoprotein/NP Protein (His)
NP Protein
|
H1N1
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-04274
|
Influenza A H1N1 (A/Brevig Mission/1/1918) Nucleoprotein/NP Protein (His)
NP Protein
|
H1N1
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-00382
|
Thioredoxin/TRX Protein, Mouse, Recombinant
Txn,Txn1,thioredoxin
|
Mouse
|
E. coli
|
|
Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. Thioredoxins are found in nearly all known organisms and are essential for life in mammals. Thioredoxin / TXN participates in various redox reactions through the reversible oxida... |
|
TMPY-01012
|
P4HB Protein, Human, Recombinant (His)
DSI,prolyl 4-hydroxylase, β polypeptide,PDIA1,PDI,GIT,ERBA2L...
|
Human
|
HEK293
|
|
Protein disulfide-isomerase, also known as Cellular thyroid hormone-binding protein, Prolyl 4-hydroxylase subunit beta, p55 and P4HB, is a peripheral membrane protein that belongs to the protein disulfide isomerase family. P4HB is highly abundant. In some cell types, it seems to be also secreted or associated with the plasma membrane, where it undergoes constant shedding and replacement from intracellular sources. P4HB localizes near CD4-enriched regions on lymphoid cell surfaces. It is identifi... |
|
TMPY-06057
|
Influenza A H3N2 (A/Hong Kong/45/2019) Nucleoprotein/NP Protein (His)
NP Protein
|
H3N2
|
Baculovirus-Insect Cells
|
|
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot... |
|
TMPY-02292
|
IGSF11 Protein, Human, Recombinant (His)
CT119,immunoglobulin superfamily, member 11,BT-IgSF,Igsf13,C...
|
Human
|
HEK293
|
|
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to overexpressed in colorectal cancers and hep... |
|
TMPJ-01471
|
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
Activin A,INHBA,Inhibin beta A chain,Inhibin β A chain
|
Human/Mouse/Rat
|
Human Cells
|
|
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell developm... |
|
TMPY-01403
|
VNN1 Protein, Human, Recombinant (His)
Tiff66,HDLCQ8,vanin 1
|
Human
|
HEK293
|
|
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one CN hydrolase domain. It is widely expressed with higher expression in spleen, kidney and blood. It is overexpressed in lesional psoriatic skin. Vanin-1 is also a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with bioti... |
|
TMPY-04870
|
Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1 protein (His)
|
ZIKV
|
HEK293
|
|
Zika virus NS1 antigen is one of seven non-structural proteins. NS1 is involved in RNA replication. The possible effects of NS1 on hosts include: localizes to host cell surface and secreted extracellularly, modulates signalling of the innate immune system, has possible damages to platelets and endothelial cells through anti-NS1 antibodies. |
|
TMPY-02157
|
GST Protein, Schistosoma japonicum, Recombinant
|
Schistosoma japonicum
|
Baculovirus-Insect Cells
|
|
Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated into an expression vector alongside the gene sequence encoding the protein of interest. Induction of protein expression from the vector's promoter results in expression of a fusion protein: the protein of interest fused to the GST protein. This GST-fusion protein can then be purifie... |
|
TMPY-02881
|
RAGE Protein, Human, Recombinant
RAGE,advanced glycosylation end product-specific receptor
|
Human
|
HEK293
|
|
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, an... |
|
TMPH-00009
|
OGT Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross-talk between glycosylation and phosphorylation or by affecting proteolytic processing. Probably by glyco... |
|
TMPY-01028
|
Ficolin 1/FCN1 Protein, Human, Recombinant (His)
FCNM,FCN1,ficolin 1,FCNA
|
Human
|
HEK293
|
|
Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. Three Ficolins have bee... |
|
TMPY-06418
|
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
R-spondin 2,CRISTIN2
|
Human
|
HEK293
|
|
R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. RSPO2 is secreted proteins that regulate beta-catenin signaling. Activator of the beta-catenin signaling cascade leads to TCF-dependent gene activation. Action both in the canonical Wnt / beta- catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled / LRP receptors. Probably also acts a... |
|
TMPY-02927
|
RAGE Protein, Human, Recombinant (His)
RAGE,advanced glycosylation end product-specific receptor
|
Human
|
HEK293
|
|
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, an... |
|
TMPJ-00037
|
FGF-2 Protein, Mouse, Recombinant
Fibroblast Growth Factor 2,bFGF,HBGF-2,Basic Fibroblast Grow...
|
Mouse
|
E. coli
|
|
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysacchari... |
|
TMPY-02533
|
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His)
insulin-like growth factor binding protein 7,PSF,IGFBP-7,FST...
|
Human
|
HEK293
|
|
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have bee... |
|
TMPY-04508
|
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc)
insulin-like growth factor binding protein 7,Mac25,AGM,Fstl2
|
Mouse
|
HEK293
|
|
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have bee... |
|
TMPY-02450
|
Cathepsin D Protein, Human, Recombinant (His)
HEL-S-130P,CLN10,cathepsin D,CPSD
|
Human
|
HEK293
|
|
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly described function is intracellular catabolism in lysosomal compartments, other physiological effect include hormone and antigen processing. Cathepsin D has a specificity similar to but narrower than that of pepsin A. Cathepsin D plays an important role in the degradation of pro... |
|
TMPY-02205
|
Beta-Catenin Protein, Human, Recombinant (His & GST)
catenin beta 1,armadillo,CTNNB,MRD19,catenin β1,β-Catenin
|
Human
|
Baculovirus-Insect Cells
|
|
beta-Catenin, also known as CTNNB1, is a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain, which is specialized for protein-protein binding. It is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. CTNNB1 also anchors the actin cytoskeleton and may be responsible for transmit... |
|
TMPY-01357
|
S100A9 Protein, Human, Recombinant (His)
MRP14,P14,LIAG,CFAG,CGLB,CAGB,NIF,MIF,S100 calcium binding p...
|
Human
|
Baculovirus-Insect Cells
|
|
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i... |
|
TMPY-02078
|
HtrA2/Omi Protein, Human, Recombinant (His)
PARK13,OMI,HtrA serine peptidase 2,PRSS25
|
Human
|
E. coli
|
|
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the peptidase S1B family. HTRA2 contains one PDZ (DHR) domain. HTRA2 is a serine protease that shows proteolytic activity against a non-specific substrate beta-casein. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor... |
|
TMPY-02698
|
CD14 Protein, Human, Recombinant (His)
CD14 antigen,monocyte differentiation antigen CD14,CD14 mole...
|
Human
|
HEK293
|
|
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... |
|
TMPY-05779
|
Ephrin A1/EFNA1 Protein, Human, Recombinant (hFc)
EPLG1,TNFAIP4,ECKLG,LERK-1,LERK1,EFL1,EFNA1,B61,ephrin-A1
|
Human
|
HEK293
|
|
EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses a... |
|
TMPY-05074
|
NKG2A/CD159a Protein, Human, Recombinant (aa 94-233, His)
CD159A,NKG2A,killer cell lectin-like receptor subfamily C, m...
|
Human
|
HEK293
|
|
NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this family are characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 contains 1 C-type lectin domain and forms a complex with another family member, KLRD1/CD94. It is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represe... |
沪公网安备 31010602006700号