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Search Results for " p38 "
Targets Recommended: p38 MAPK p38 MAPK

169

抑制剂 & 化合物

79

天然产物

1

TargetMol 试剂盒

38

重组蛋白

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Cat. No. Product Name Form Specificity Of Inhibition
CL0118 p38 inhibitor kit

p38 inhibitor kit

TargetMol 试剂盒

p38 inhibitor kit
Cat.No: CL0118
Cat. No. Product Name Target Signaling Pathways
T36010 p38 MAPK Inhibitor

p38 MAPK MAPK
p38 MAPK Inhibitor 是p38 MAPK 激酶的有效抑制剂(IC50= 35 nM)。p38 MAPK Inhibitor 抑制癌基因RAS 诱导的衰老。
T12347 p38-α MAPK-IN-1

p38 MAPK; Autophagy Autophagy; MAPK
p38-α MAPK-IN-1 是一种 MAPK14 (p38-α) 抑制剂,在 EFC 置换试验和 HTRF 试验中 IC50 分别为 2300 nM 和 5500 nM。
T36011 p38 MAP Kinase Inhibitor IV

p38 MAPK Inhibitor IV

p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α and IL-1β cytokine production (IC50s = 22 and 44 nM, respectively) in human peripheral blood mononuclear cells.
T35420 (S)-p38 MAPK Inhibitor III

(S)-p38 MAPK Inhibitor III

(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively).
T67944 p38 MAP Kinase Inhibitor Ⅵ

p38 MAPK MAPK
p38 MAP Kinase Inhibitor Ⅵ是一种有效的p38 MAP Kinase 抑制剂,具有抗炎活性。
T11241 p38 MAPK-IN-2

Others Others
p38 MAPK-IN-2 is an inhibitor of p38 kinase.
T16424 p38 MAPK-IN-1

p38 MAPK MAPK
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
T70638 p38-α MAPK-IN-5

p38-α MAPK-IN-5 是一种有效的 p38α抑制剂,对 p38α、p38 β、p38γ、p38δ 的 IC50分别为 0.1 nM、0.2 nM、944 nM、4100 nM。p38-α MAPK-IN-5 具有抗炎作用,并且具有用于哮喘和慢性阻塞性肺病 (COPD) 研究的潜力。
T61803 p38 MAPK-IN-3

p38 MAPK-IN-3 (Compound 2c) is a potent inhibitor of p38α MAPK, displaying antitumor properties by promoting apoptosis and increasing reactive oxygen species (ROS) production [1].
T79028 p38 Kinase inhibitor 4

p38 MAPK MAPK
p38 Kinase inhibitor 4 (compound 135) 是高效的 p38 MAP Kinase 抑制剂,具有显著的生物活性。
T78652 p38α inhibitor 4

p38 MAPK MAPK
p38α inhibitor 4 是一种选择性 MAPK p38α抑制剂,看而用于研究糖尿病、疼痛和慢性炎症。
T67830 p38α inhibitor 3

p38 MAPK MAPK
p38α inhibitor 3是一种丝裂原活化蛋白激酶P38α的抑制剂,可以有效阻断成肌细胞分化。
T2513 VX-702

p38 MAPK; Autophagy Autophagy; MAPK
VX702 是一种高度特异性的 p38α MAPK 抑制剂,对 p38α 的选择性比 p38β 高 14 倍。它是一种小分子研究口服抗细胞因子疗法,用于治疗炎症性疾病,如类风湿性关节炎。
T6976 SB 239063

SB239063

p38 MAPK; Autophagy Autophagy; MAPK
SB 239063 (SB239063) 是一种选择性、可口服的 p38 MAPK 抑制剂,对重组纯化的人 p38α 的 IC50值为 44 nM,具有抗哮喘作用,还被用于增强因衰老或疾病受损的记忆,如阿尔茨海默病。
T61091 p38-α MAPK-IN-4

p38-α MAPK-IN-4 (Compound 69) 是一种选择性的p38α MAPK 抑制剂,IC50为 1.5 μM。p38-α MAPK-IN-4 在体内可快速、强烈地抑制机械性触诱发痛 (mechanical allodynia) 的发生。
T4078 SB 242235

SB-242235,SB242235

p38 MAPK; Autophagy Autophagy; MAPK
SB 242235 是一种有效的选择性 p38 MAP 激酶抑制剂,可能是细胞因子介导疾病的有效疗法,在人的软骨细胞中 IC50值为 1.0 μM。
T14381 AZD7624

AZD-7624

p38 MAPK; TNF Apoptosis; MAPK
AZD7624 是一种 p38 抑制剂,具有强大的抗炎活性。
T61440 TOPK-p38/JNK-IN-1

TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO production. It demonstrates anti-inflammatory properties by inhibiting downstream phosphorylation of related proteins and preventing the degradation of TOPK [1].
T10277 AL 8697

p38 MAPK MAPK
AL 8697 是一种特异性 p38α MAPK 抑制剂 (IC50 = 6 nM),其特异性是 p38β (IC50 = 82 nM) 的 14 倍,是其他 91 种激酶的 300 倍。 AL 8697 具有抗炎活性。
T4645 TA-01

p38 MAPK; Casein Kinase; Autophagy Autophagy; MAPK; Metabolism; Stem Cells
TA01 是一种心源性抑制剂,有效抑制CK1和p38 MAPK,其对 CK1ε,CK1δ 和 p38 MAPK 的IC50值分别为 6.4 nM,6.8 nM 和 6.7 nM。
T1974 PH-797804

PH797804

p38 MAPK; Autophagy Autophagy; MAPK
PH-797804 是一种 ATP 竞争性的,选择性的p38α/p38β抑制剂,对 p38α 的IC50为 26 nM,Ki 值为 5.8 nM,对 p38β 的Ki 值为 40 nM。
T16350 NSC-87877

Apoptosis; Phosphatase Apoptosis; Metabolism
NSC-87877 是一种Shp2和Shp1蛋白质酪氨酸磷酸酶抑制剂,IC50值分别为0.318 μM 和0.355 μM。它还抑制双特异性磷酸酶26。
T6934 Pexmetinib

ARRY-614

Tie-2; p38 MAPK; Autophagy Autophagy; MAPK; Tyrosine Kinase/Adaptors
Pexmetinib (ARRY-614) 是一种口服生物可利用的双重 p38 MAPK/Tie-2 抑制剂,可研究急性骨髓性白血病。在 HEK-293 细胞系中的 IC50 为 4 nM/18 nM。
T7367 Acumapimod

BCT-197

p38 MAPK; Autophagy Autophagy; MAPK
Acumapimod (BCT-197) 是一种有口服活性的p38 MAP 激酶抑制剂,IC50值小于1 μM。
T6089 Neflamapimod

VX-745

p38 MAPK; Autophagy Autophagy; MAPK
Neflamapimod (VX-745) 是一种可穿过血脑屏障的,高选择性的p38α抑制剂,对 p38α 的IC50值为 10 nM,p38β 的IC50值为 220 nM。它对 p38β 的特异性高 22 倍,具有抗炎活性。
T6130 Skepinone-L

CBS3830

p38 MAPK; Autophagy Autophagy; MAPK
Skepinone-L (CBS3830) 是一种选择性 p38 丝裂原活化蛋白激酶抑制剂。
T9697 ASK1-IN-1

ASK Apoptosis
ASK1-IN-1 是一种凋亡信号调节激酶 1(SK1) 抑制剂,具有良好的效价 (细胞IC50=138 nM; BiochemicalIC50=21 nM)。ASK1-IN-1具有中枢神经系统渗透性。
T2432 PD 169316

Virus Protease; p38 MAPK; Autophagy Autophagy; MAPK; Microbiology/Virology
PD 169316 是一种细胞渗透性 p38 MAP 激酶抑制剂,IC50值为 89 nM。它可选择性地抑制磷酸化 p38 的激酶活性。
T6277 Doramapimod

BIRB 796,达马莫德,度马莫德

Raf; p38 MAPK; Autophagy Autophagy; MAPK
Doramapimod (BIRB 796) 是一种具有口服活性的p38 MAPK 抑制剂,Kd 值为0.1nM。它也抑制B-Raf 和 Abl,IC50分别为 83 nM 和 14.6 μM。
T11898 LXH254

Raf MAPK
LXH254 是B/C RAF 抑制剂。
T2367 SKF-86002

SKF86002

p38 MAPK; TNF Apoptosis; MAPK
SKF-86002 是一种可口服的 p38 MAPK 抑制剂,具有抗炎和抗关节炎活性,可用于缓解疼痛的研究。它能抑制脂氧合酶和环氧合酶介导的花生四烯酸代谢,还抑制脂多糖 (LPS) 刺激人单核细胞产生 IL-1 和 TNF-α,IC50为 1 μM。
T5494 MW-150

MW01-18-150SRM

p38 MAPK; Autophagy Autophagy; MAPK
MW-150 (MW01-18-150SRM) 是一种选择性、CNS 渗透性和口服活性的 p38α MAPK 抑制剂,Ki 为 101 nM。它可抑制内源性 p38α MAPK 在活化的神经胶质中磷酸化内源性底物 MK2 的能力。
T12979 BI-3406

p38 MAPK; MAPK; Ras GPCR/G Protein; MAPK
BI-3406 是一种可口服、高效且选择性的 KRAS-SOS1 抑制剂,具有抗癌活性。它有效减少 GTP 加载的 KRAS 的形成,抑制 MAPK 信号通路。它还抑制 KRAS 与 SOS1之间相互作用,IC50为 6 nM。
T4597 UM-164

UM164,DAS-DFGO-II

p38 MAPK; Src; Autophagy Angiogenesis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
UM-164 (DAS-DFGO-II) 是一种高效的c-Src 抑制剂,Kd 为 2.7 nM。它还抑制p38α和p38β活性。
T6150 TAK-715

p38 MAPK; Casein Kinase; JNK MAPK; Metabolism; Stem Cells
TAK-715 是一种具有口服活性的p38 MAPK 抑制剂,对 p38α 和 p38β 的IC50分别为 7.1 nM 和200 nM。它抑制酪蛋白激酶 I (CK1δ/ε),调节 Wnt/β-catenin 信号传导的激活,有抗炎活性。
T12997 SR-318

p38 MAPK; TNF Apoptosis; MAPK
SR-318 是p38 MAPK 的选择性抑制剂,对 p38α,p38β 和 p38α/β 的IC50分别为 5 nM,32 nM 和 6.11 μM。它有效抑制全血中TNF-α的释放,IC50为 283 nM。它显示出抗癌和抗炎活性。
T6911 NSC-87877 disodium

NSC87877

Apoptosis; Phosphatase Apoptosis; Metabolism
NSC-87877 disodium (NSC87877) 是一种有效的Shp2和Shp1蛋白质酪氨酸磷酸酶抑制剂,IC50值分别为0.318 μM 和0.355 μM。NSC-87877还抑制双特异性磷酸酶26。
T12871 Talmapimod

他匹莫德,SCIO-469

p38 MAPK MAPK
Talmapimod (SCIO-469) 是 选择性的,具有口服活性的,ATP 竞争性的 p38α抑制剂,对 p38α和 p38β的 IC50 值分别是 9 nM 和90 nM。Talmapimod 在 20 个其他激酶 (包括其他 MAPKs) 上显示出至少 2000 倍的选择性。
T3462 BMS-582949 hydrochloride

BMS-582949 HCl

p38 MAPK; Autophagy Autophagy; MAPK
BMS-582949 hydrochloride (BMS-582949 HCl) 是一种高度特异性的 p38α MAPK 抑制剂,其 IC50值为13 nM,可研究炎症性疾病。
T50005 Sertaconazole

Antifungal Microbiology/Virology
Sertaconazole 是一种广谱抗真菌药。
T2301 SB 202190

FHPI,SB202190

Apoptosis; p38 MAPK; Autophagy Apoptosis; Autophagy; MAPK
SB 202190 (FHPI) 是一种 p38 MAPK 抑制剂,可以抑制 p38α 和 p38β2 (IC50=50/100 nM),具有选择性和细胞渗透性。SB 202190 具有抗肿瘤活性,还可以诱导人胚胎干细胞向心肌细胞分化。
T4646 TA-02

p38 MAPK; Autophagy Autophagy; MAPK
TA02 是一种Adezmapimod 类似物,是p38 MAPK 的抑制剂,其IC50值为 20 nM。它和Adezmapimod、SB 202190 具有相似的心源活性,可抑制 TGFBR-2。
T12352 Oxidopamine hydrochloride

6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride,6-羟基多巴胺盐酸盐

Mitophagy; Dopamine Receptor; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) 是一种神经递质多巴胺拮抗剂,可选择性地破坏多巴胺能神经元,是一种广泛使用的神经毒素。
T13099 TC ASK 10

ASK; MAPK Apoptosis; MAPK
TC ASK 10 是选择性的,口服有效的细胞凋亡信号调节激酶 1 抑制剂,IC50为 14 nM。它对其他代表性激酶的抑制活性低于 50%,除 ASK2之外 (IC50为 0.51 μM)。
T16159 Muramyl dipeptide

MDP

NOD Immunology/Inflammation; NF-κB
Muramyl dipeptide (MDP) 是合成的免疫反应肽,由 N-乙酰壁酸与 L-Ala-D-isoGln 的短氨基酸链相连。它通过MAPK 途径上调 Runx2 基因表达,直接促进成骨细胞分化,通过降低 RANKL/OPG 比值间接抑制破骨细胞分化。它是通过Runx2诱导骨形成的诱导因子,也是NLRP1激动剂。
T7123 AMG-47a

VEGFR; p38 MAPK; JAK; Src Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Stem Cells; Tyrosine Kinase/Adaptors
AMG-47a 是具有口服活性的 Lck 抑制剂,IC50值为 0.2 nM。它具有抗炎作用,对 VEGF2、p38α、p38α、Jak3、MLR 和 IL-2的 IC50值分别为 1、3、72、30 和 21 nM。
T12850 Dilmapimod

SB-681323,GW 681323,度马莫得

p38 MAPK; Autophagy Autophagy; MAPK
Dilmapimod (SB-681323) 是一种 p38 MAPK 的强效抑制剂,可抑制慢性阻塞性肺疾病的炎症。
T12352L Oxidopamine hydrobromide

6-Hydroxydopamine hydrobromide,6-羟基多巴胺氢溴酸盐,6-OHDA hydrobromide

Mitophagy; Dopamine Receptor; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Oxidopamine hydrobromide (6-OHDA hydrobromide) 是一种神经递质多巴胺拮抗剂,可选择性地破坏多巴胺能神经元,是一种广泛使用的神经毒素。
T22115 SM-7368

NF-κB NF-κB
NF-κB Activation Inhibitor III 是一种NF-kB 抑制剂,抑制 TNF-α 诱导的MMP-9上调,靶向抑制下游的MAPK p38,可用于靶向 TNF-α 介导的肿瘤侵袭和转移的化疗研究。
T7661 SD-169

SD 169,1H-吲哚-5-甲酰胺

p38 MAPK MAPK
SD-169 (SD 169) 是一种可口服的 ATP 竞争性MAPK p38α抑制剂,IC50值为 3.2 nM。它对p38β MAPK 的IC50值为 122 nM。它通过抑制 T 细胞的浸润和活化阻止糖尿病的发展。

化合物

p38 MAPK Inhibitor
Cat.No: T36010
Synonym:
Target: p38 MAPK
p38-α MAPK-IN-1
Cat.No: T12347
Synonym:
Target: p38 MAPK, Autophagy
p38 MAP Kinase Inhibitor IV
Cat.No: T36011
Synonym: p38 MAPK Inhibitor IV
Target:
(S)-p38 MAPK Inhibitor III
Cat.No: T35420
Synonym: (S)-p38 MAPK Inhibitor III
Target:
p38 MAP Kinase Inhibitor Ⅵ
Cat.No: T67944
Synonym:
Target: p38 MAPK
p38 MAPK-IN-2
Cat.No: T11241
Synonym:
Target: Others
p38 MAPK-IN-1
Cat.No: T16424
Synonym:
Target: p38 MAPK
p38-α MAPK-IN-5
Cat.No: T70638
Synonym:
Target:
p38 MAPK-IN-3
Cat.No: T61803
Synonym:
Target:
p38 Kinase inhibitor 4
Cat.No: T79028
Synonym:
Target: p38 MAPK
p38α inhibitor 4
Cat.No: T78652
Synonym:
Target: p38 MAPK
p38α inhibitor 3
Cat.No: T67830
Synonym:
Target: p38 MAPK
VX-702
Cat.No: T2513
Synonym:
Target: p38 MAPK, Autophagy
SB 239063
Cat.No: T6976
Synonym: SB239063
Target: p38 MAPK, Autophagy
p38-α MAPK-IN-4
Cat.No: T61091
Synonym:
Target:
SB 242235
Cat.No: T4078
Synonym: SB-242235,SB242235
Target: p38 MAPK, Autophagy
AZD7624
Cat.No: T14381
Synonym: AZD-7624
Target: p38 MAPK, TNF
TOPK-p38/JNK-IN-1
Cat.No: T61440
Synonym:
Target:
AL 8697
Cat.No: T10277
Synonym:
Target: p38 MAPK
TA-01
Cat.No: T4645
Synonym:
Target: p38 MAPK, Casein Kinase, Autophagy
PH-797804
Cat.No: T1974
Synonym: PH797804
Target: p38 MAPK, Autophagy
NSC-87877
Cat.No: T16350
Synonym:
Target: Apoptosis, Phosphatase
Pexmetinib
Cat.No: T6934
Synonym: ARRY-614
Target: Tie-2, p38 MAPK, Autophagy
Acumapimod
Cat.No: T7367
Synonym: BCT-197
Target: p38 MAPK, Autophagy
Neflamapimod
Cat.No: T6089
Synonym: VX-745
Target: p38 MAPK, Autophagy
Skepinone-L
Cat.No: T6130
Synonym: CBS3830
Target: p38 MAPK, Autophagy
ASK1-IN-1
Cat.No: T9697
Synonym:
Target: ASK
PD 169316
Cat.No: T2432
Synonym:
Target: Virus Protease, p38 MAPK, Autophagy
Doramapimod
Cat.No: T6277
Synonym: BIRB 796,达马莫德,度马莫德
Target: Raf, p38 MAPK, Autophagy
LXH254
Cat.No: T11898
Synonym:
Target: Raf
SKF-86002
Cat.No: T2367
Synonym: SKF86002
Target: p38 MAPK, TNF
MW-150
Cat.No: T5494
Synonym: MW01-18-150SRM
Target: p38 MAPK, Autophagy
BI-3406
Cat.No: T12979
Synonym:
Target: p38 MAPK, MAPK, Ras
UM-164
Cat.No: T4597
Synonym: UM164,DAS-DFGO-II
Target: p38 MAPK, Src, Autophagy
TAK-715
Cat.No: T6150
Synonym:
Target: p38 MAPK, Casein Kinase, JNK
SR-318
Cat.No: T12997
Synonym:
Target: p38 MAPK, TNF
NSC-87877 disodium
Cat.No: T6911
Synonym: NSC87877
Target: Apoptosis, Phosphatase
Talmapimod
Cat.No: T12871
Synonym: 他匹莫德,SCIO-469
Target: p38 MAPK
BMS-582949 hydrochloride
Cat.No: T3462
Synonym: BMS-582949 HCl
Target: p38 MAPK, Autophagy
Sertaconazole
Cat.No: T50005
Synonym:
Target: Antifungal
SB 202190
Cat.No: T2301
Synonym: FHPI,SB202190
Target: Apoptosis, p38 MAPK, Autophagy
TA-02
Cat.No: T4646
Synonym:
Target: p38 MAPK, Autophagy
Oxidopamine hydrochloride
Cat.No: T12352
Synonym: 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride,6-羟基多巴胺盐酸盐
Target: Mitophagy, Dopamine Receptor, Autophagy
TC ASK 10
Cat.No: T13099
Synonym:
Target: ASK, MAPK
Muramyl dipeptide
Cat.No: T16159
Synonym: MDP
Target: NOD
AMG-47a
Cat.No: T7123
Synonym:
Target: VEGFR, p38 MAPK, JAK, Src
Dilmapimod
Cat.No: T12850
Synonym: SB-681323,GW 681323,度马莫得
Target: p38 MAPK, Autophagy
Oxidopamine hydrobromide
Cat.No: T12352L
Synonym: 6-Hydroxydopamine hydrobromide,6-羟基多巴胺氢溴酸盐,6-OHDA hydrobromide
Target: Mitophagy, Dopamine Receptor, Autophagy
SM-7368
Cat.No: T22115
Synonym:
Target: NF-κB
SD-169
Cat.No: T7661
Synonym: SD 169,1H-吲哚-5-甲酰胺
Target: p38 MAPK
Cat. No. Product Name Target Signaling Pathways
T3400 Bakuchiol

p38 MAPK; DNA/RNA Synthesis; Autophagy Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; MAPK
Bakuchiol 是一种从补骨脂种子中提取的植物雌激素,具有抗肿瘤和抗蠕虫特性,以及细胞毒活性和抗菌活性。
TN1445 Bisabolangelone

p38 MAPK; MAPK MAPK
Bisabolangelone 是从没药中分离出来的一种倍半萜衍生物,具有抗炎作用。它通过阻断巨噬细胞内的NF-kappaB 和MAPK 通路抑制脂多糖刺激的炎症,具有抗溃疡作用。
T5S2283 Sesamolin

p38 MAPK; Caspase; JNK Apoptosis; MAPK; Proteases/Proteasome
Sesaminol 是从Justicia orbiculata 中分离得到的一种天然产物,抑制脂质过氧化,具有神经保护作用和抗氧化活性。它通过抑制JNK、p38 MAPKs 和caspase-3磷酸化,抑制MAPK 的级联反应。
TN1721 Gypenoside L

ERK; p38 MAPK; Calcium Channel; NF-κB; ROS Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Metabolism; NF-κB
Gypenoside L 是存在于绞股蓝中的一种皂苷,可增加 SA-β-半乳糖苷酶活性,促进衰老相关分泌细胞因子的产生。它还可以激活p38和ERK MAPK 通路和NF-κB 通路以诱导衰老,具有抗肿瘤和抗炎活性。
T2565 Hesperetin

橙皮素

Apoptosis; p38 MAPK; 5-HT Receptor; Autophagy; TGF-beta/Smad Apoptosis; Autophagy; GPCR/G Protein; MAPK; Neuroscience; Stem Cells
Hesperetin 是一种天然黄烷酮类物质,是人UGT 的广谱抑制剂,可诱导凋亡。
T2885 Esculin

秦皮甲素,马栗树皮甙,Aesculin

Antiviral; p38 MAPK; Antibacterial Immunology/Inflammation; MAPK; Microbiology/Virology
Esculin (Aesculin) 是灰树皮的荧光香豆素葡萄糖苷,可通过 MAPK 信号通路改善实验性糖尿病肾病的认知障碍,并发挥抗氧化应激和抗炎作用。
T0539 Dihydrocaffeic acid

二氢咖啡酸,Hydrocaffeic acid

Antioxidant; p38 MAPK; Endogenous Metabolite MAPK; Metabolism; oxidation-reduction
Dihydrocaffeic acid (Hydrocaffeic acid) 是绿原酸的代谢物,是一种众所周知的抗氧化成分,具有抗氧化、抗阿尔茨海默病、神经保护、唤醒和降脂作用。
T3860 Isoliquiritin apioside

MMP; p38 MAPK; NF-κB MAPK; NF-κB; Proteases/Proteasome
Isoliquiritin apioside 可抑制癌细胞和内皮细胞的侵袭和血管生成,显著降低 PMA 诱导的MMP9活性增加,并抑制 PMA 诱导的MAPK 和NF-κB 活化。
T7051 5,6,7-TRIMETHOXYFLAVONE

Baicalein Trimethyl Ether,黄岑素-5,6,7-三甲醚

p38 MAPK MAPK
5,6,7-Trimethoxyflavone 是从日本紫珠提取出的一种天然产物,是 p38-α MAPK 抑制剂,具有抗炎作用。
T5S2358 Dehydrocorydaline

Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine

BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
Dehydrocorydaline (13-Methylpalmatine) 是一种生物碱。它调节Bax,Bcl-2蛋白表达,激活caspase-7,caspase-8,并使PARP 失活。它能增强p38 MAPK 活化,具有抗炎、抗癌等功效。它具有强大的抗疟疾作用,并具低细胞毒性。
T5S0506 Rotundic acid

Rutundic acid,铁冬青酸

Apoptosis; Others; p38 MAPK; Akt; mTOR Apoptosis; Cytoskeletal Signaling; MAPK; Others; PI3K/Akt/mTOR signaling
Rotundic acid (Rutundic acid) 是一种从圆形肠球菌中获得的三萜类天然产物,具有抗炎和保护心脏的能力。它可通过 AKT/mTOR 和 MAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。
TN1968 N-​Feruloyloctopamine

N-Feruloyloctopamine,N-阿魏酰章鱼胺

p38 MAPK; Akt Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
N-Feruloyloctopamine 是从木本曼陀罗提取的一种天然产物,有抗氧化作用,可显著降低Akt 和p38 MAPK 磷酸化水平。
T5S0089 Kaempferol-3-O-glucorhamnoside

Kaempferol 3-glucorhamnoside,百蕊草素I

Antioxidant; p38 MAPK; NF-κB MAPK; NF-κB; oxidation-reduction
Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside) 是来源于百蕊草的一种类黄酮,在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T5S0761 Nitidine chloride

Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的,具有抗疟疾活性。它通过多个靶点通路,起抗癌作用,抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
T10990 Dehydrocorydaline chloride

盐酸脱氢紫堇碱,13-Methylpalmatine chloride

BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
Dehydrocorydaline chloride (13-Methylpalmatine chloride) 是生物碱。Dehydrocorydaline 调节 Bax,Bcl-2蛋白表达;激活 caspase-7,caspase-8,并使 PARP 失活。它能增强 p38 MAPK 活化,具有抗炎、抗癌等功效。它具有强大的抗疟疾作用,并具低细胞毒性。
T4S2326 Cornuside

7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

ERK; p38 MAPK; NF-κB; JNK MAPK; NF-κB
Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷,可用于炎症疾病的研究和促进血液循环。 它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应,用于炎性过敏性疾病中的潜能。
T2S2362 Dehydrocorydaline nitrate

去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱

BCL; Others; PARP; p38 MAPK; Caspase; Parasite; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Others; Proteases/Proteasome
Dehydrocorydaline nitrate 是生物碱。Dehydrocorydaline 调节 Bax,Bcl-2蛋白表达,激活 caspase-7,caspase-8,并使 PARP 失活。它能增强 p38 MAPK 活化,具有抗炎、抗癌、抗疟疾等功效。
TL0004 FERULIC ACID METHYL ESTER

阿魏酸甲酯,Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate

p38 MAPK; Autophagy Autophagy; MAPK
FERULIC ACID METHYL ESTER (Methyl ferulate) 是从大百部中分到的阿魏酸衍生物,具有抗氧化和抗炎作用。在原发性骨髓源性巨噬细胞中,它抑制 COX-2 的表达,降低 p-p38和 p-JNK 的水平。它能够透过细胞膜和血脑屏障,清除自由基,可研究神经退行性疾病。
T6427 Butein

2’,3,4,4’-tetrahydroxy Chalcone,紫铆因

Apoptosis; EGFR; Others; PDE; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Others; Tyrosine Kinase/Adaptors
Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂,也是蛋白酪氨酸激酶抑制剂,还是一种SIRT1激活剂。它通过 AKT 和 ERK/p38 MAPK 通路,靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
T9218 Andrograpanin

19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元

p38 MAPK MAPK
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) 是来自穿心莲的一种天然产物,具有抗炎和抗感染活性。
T0518 Methacycline hydrochloride

Rondomycin,盐酸甲烯土霉素,盐酸美他环素,Methacycline HCl

ribosome; Antibacterial; Antibiotic Microbiology/Virology
Methacycline hydrochloride (Rondomycin) 是四环素抗生素,可抑制细菌蛋白质的合成。它是上皮-间质转化 (EMT) 抑制剂。它在体外可阻断 EMT,体内抑制纤维发生,不会直接影响 TGF-β1 Smad 信号传导。它是抗菌剂,有潜力研究肺纤维化。
T5281 Skatole

粪臭素,Scatole,3-Methylindole,3-​Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole

AhR; p38 MAPK; Aryl Hydrocarbon Receptor; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
Skatole (3-Methyl-1H-indole) 是由肠道菌群产生的,通过激活芳基烃受体和 p38调节肠上皮细胞功能。
T2755 Rhoifolin

野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Others; p38 MAPK; NF-κB; transporter; IGF-1R; Autophagy Autophagy; MAPK; Metabolism; NF-κB; Others; Tyrosine Kinase/Adaptors
Rhoifolin (Apigenin 7-O-neohesperidoside) 是从琯溪蜜柚叶子分离的一种黄酮糖苷。它通过 RANKL 诱导的NF-κB 和MAPK 途径改善钛颗粒刺激的骨溶解并减少破骨细胞生成。它通过增强脂联素分泌,胰岛素受体-β的酪氨酸磷酸化和GLUT4易位有助于治疗糖尿病并发症。
T4085 Paris saponin VII

重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Apoptosis; BCL; Others; PARP; p38 MAPK; Akt; Caspase; P-gp; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Membrane transporter/Ion channel; Neuroscience; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Paris saponin VII (Dioscini) 是从延龄草的根和根茎中分离的一种甾体皂苷。它减弱线粒体膜电位,增加凋亡相关蛋白的表达,并降低Bcl-2、caspase-9、caspase-3、PARP-1和p-Akt 的蛋白表达水平。它在 K562/ADR 细胞中诱导强烈的自噬,可研究白血病。
T3908 10-Gingerol

10-姜酚

Apoptosis Apoptosis
10-Gingerol 是一种姜根脂的主要刺激性成分,具有抗炎、抗氧化和抗增殖作用,能够抑制 MDA-MB-231 肿瘤细胞的增殖(IC50:12.1 μM)。
TN1879 Lucideric acid A

Lucidenic acid A,赤芝酸A

MMP; p38 MAPK; JNK MAPK; Proteases/Proteasome
Lucideric acid A (Lucidenic acid A) 是分离自灵芝的天然产物,可抑制 PMA 诱导的MMP-9活性,具有抵抗肝癌细胞侵袭的作用。
T3892 Isoacteoside

异麦角甾苷,Isoverbascoside

NF-κB NF-κB
Isoacteoside 具有抗炎作用,通过作用于 caspase-1、丝裂原活化蛋白激酶(c-Jun N-末端激酶、p38、细胞外信号调节蛋白激酶)和核因子-kappa B 途径介导。
T10383 Asatone

NF-κB NF-κB
Asatone 是一种从细辛中分离到的活性成分,通过活化 NF-κB 及下调 p-MAPK (ERK,JNK 和 p38) 通路起作用,具有抗炎作用。
T2845 Imperatorin

Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen

TRP/TRPV Channel; AChR; AChE; NOD Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB
Imperatorin (8-Isopentenyloxypsoralene) 是NO synthesis 和BChE 的抑制剂,IC50分别为 9.2 μmol 和 31.4 μmol。它也是TRPV1的微弱激动剂,EC50为 12.6±3.2 μM。
T5S0168 Atractylenolide II

2-Atractylenolide,Asterolide,苍术内酯II

Apoptosis; ERK; p38 MAPK; Akt; STAT Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
Atractylenolide II (2-Atractylenolide) 是一种从白术干燥根茎分离的倍半萜类天然产物,具有抗增殖活性。
T5S0581 Sec-O-Glucosylhamaudol

亥茅酚苷,Hamaudol 3-glucoside

Others; Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience; Others
Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) 是从滨海前胡中分离得到的一种天然产物,能够降低 μ 阿片受体的蛋白水平,可用于缓解疼痛的研究。它通过调节脂多糖刺激的 RAW264.7 细胞系中的 p38 丝裂原活化蛋白激酶具有抗炎作用。
T3896 Shanzhiside methyl ester

三栀子甙甲酯,山芝皂苷甲酯

Glucagon Receptor GPCR/G Protein
Shanzhiside methyl ester 是一种小分子胰高血糖素样肽 1 受体激动剂,分离自轮状乳杆菌,能够诱导抗异常性痛觉耐受。
T3816 Velutin

NF-κB; HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism; NF-κB
Velutin 是一种苷元,提取自槲寄生中,能够抑制黑色素生物合成。它利用 NF-κB 途径减少破骨细胞分化和下调 HIF-1α。
T3884 Neoandrographolide

Neoandrographiside,新穿心莲内酯

NOS; COX Immunology/Inflammation; Neuroscience
Neoandrographolide (Neoandrographiside) 是一种二萜类化合物,从穿心莲中分离得到。
T3008 Lawsone methyl ether

2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone,2-甲氧基-1,4-萘并醌

Apoptosis; Antibacterial; Antifungal Apoptosis; Microbiology/Virology
Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) 是从凤仙花和Swertia calycina 中分离出的,有抗真菌和抗菌活性。
T5S1058 Triptonide

雷公藤内酯酮,PG 492,NSC 165677

Apoptosis; Wnt/beta-catenin; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Stem Cells
Triptonide (PG 492) 是从雷公藤中鉴定出的一种天然产物,是一种 Wnt 信号抑制剂,其 IC50约为 0.3 nM。它具有免疫抑制、抗炎、避育、神经保护和抗淋巴瘤作用。
T6S1597 Mulberroside A

桑皮苷 A,桑皮苷A

TNF; Tyrosinase; Interleukin Apoptosis; Immunology/Inflammation; Proteases/Proteasome
Mulberroside A 是桑中的一种主要活性成分,可降低TNF-α、IL-1β和IL-6的表达,抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化 。它抑制蘑菇酪氨酸酶,具有抗炎和抗细胞凋亡作用。
TN1711 Gossypetin

Antioxidant; p38 MAPK; MAPK; Antibacterial MAPK; Microbiology/Virology; oxidation-reduction
Gossypetin 是一种可从Rhodiola rosea Linn.中提取的六羟基化的类黄酮,是一种有效的 MKK3 和 MKK6 抑制剂,可强烈减弱 MKK3/6-p38 信号传导途径。Gossypetin 具有抗突变、抗动脉粥样硬化、抗氧化以及细胞保护和抗菌作用,它通过下调溶酶体酪蛋白酶 K 的活性和诱导肌动蛋白环破骨细胞中的自噬相关蛋白来抑制骨吸收。
T3763 Fumaric acid

Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,反丁烯二酸,Donitic acid,Allomaleic acid,富马酸

Endogenous Metabolite Metabolism
Fumaric acid (2-Butenedioic acid) 与烟酸酶缺乏症相关,是癌症相关的内源性代谢物。
T20793 Magnesium Lithospermate B

丹參酸B鎂,Monomethyl lithospermate B,丹参酸 B 镁,Lithospermate B

Others Others
Magnesium Lithospermate B 是一种咖啡酸四聚体的衍生物,从Salviae miltiorrhizae 中提取得到。它能够抑制神经炎症并减轻神经变性。它被广泛用于心血管疾病的研究,并且可以防止葡萄糖引起的细胞内氧化损伤。
T5814 Aurantiamide

TMC-58B,橙黄胡椒酰胺

p38 MAPK; NF-κB MAPK; NF-κB
Aurantiamide 是马齿苋的活性成分,具有多种生物活性(如抗氧化、抗血小板、抗炎、抗肿瘤活性等),具有口服活性。
T2768 Saikosaponin A

柴胡皂苷A,柴胡皂苷 A

NF-κB; Antibacterial; Liver X Receptor Metabolism; Microbiology/Virology; NF-κB
Saikosaponin A 是银柴胡中的主要活性成分,有抗炎活性,可上调 LXRα的表达。
T7030 anemarsaponin B

知母皂苷B,知母皂苷 B

p38 MAPK; NF-κB; MEK; COX; NO Synthase Immunology/Inflammation; MAPK; Neuroscience; NF-κB
Anemarsaponin B 是一种甾体皂苷,可降低iNOS 和COX-2的蛋白和 mRNA 水平,减少促炎细胞因子的表达和产生。它通过阻断 IκBα 的磷酸化来抑制NF-κB 的 p65 亚基的核转位,还抑制 MAP 激酶激酶 3/6 (MKK3/6) 和混合谱系激酶 3 的磷酸化。
TWS1977 Kamebakaurin

尾叶香茶菜丙素,Kamebakaurine

NF-κB NF-κB
Kamebakaurin (Kamebakaurine) 是一种提取自Isodon japonicus 中的天然产物,是一种NF-κB 的抑制剂,能够抑制 p50 的 DNA 结合活性。
TN1586 Dihydrorotenone

Apoptosis; Mitochondrial Metabolism Apoptosis; Metabolism
Dihydrorotenone 是一种线粒体抑制剂,是天然杀虫剂。它通过触发内质网应激并激活 p38 信号通路来诱导人浆细胞凋亡,可能诱发帕金森综合症。
TN5888 Toddaculin

Others Others
Toddaculin 是一种天然香豆素,抑制过度的破骨细胞活性并增强成骨细胞分化和矿化。它可诱导白血病细胞分化和凋亡,具有抗炎活性。
T3676 Sesamol

1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol,芝麻酚

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Sesamol (1,3-Benzodioxol-5-ol) 是芝麻油的主要成分,具有抗氧化和抗肿瘤活性。它是一种自由基清除剂,在 DPPH 实验中,IC50为 5.95±0.56 μg/mL。
T3S0013 Ethyl trans-caffeate

咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester

Others Others
Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) 具有抗炎作用。 它是一种有前途的天然化合物,未来在慢性肝病中的应用。它是一种有效的化学预防化合物,可防止因太阳紫外线照射引起的皮肤癌变。它是与人胰腺α-淀粉酶复合的代表性抑制剂的高分辨率结构。 它强烈抑制 JB6 Cl41细胞的肿瘤转化,无毒性。 PI3K、ERK1/2 和 p38 激酶活性在体外通过与 HOEC 直接结合而受到抑制。
TN1448 (-)-Bornyl acetate

L-(-)-Bornyl acetate,左旋乙酸冰片酯,Bornyl acetate,(-)-乙酸龙脑酯

p38 MAPK; NF-κB; JNK; Antifungal MAPK; Microbiology/Virology; NF-κB
(-)-Bornyl acetate (L-(-)-Bornyl acetate) 是存在于牛膝草油中的一种具有抗真菌活性的 (+)-Bornyl acetate 低活性异构体。
T3923 Calycosin

Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮

Apoptosis; Tyrosinase Apoptosis; Proteases/Proteasome
Calycosin (Cyclosin) 是一抗氧化和抗炎症活性天然产物。
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天然产物

Bakuchiol
Cat.No: T3400
Synonym:
Target: p38 MAPK, DNA/RNA Synthesis, Autophagy
Bisabolangelone
Cat.No: TN1445
Synonym:
Target: p38 MAPK, MAPK
Sesamolin
Cat.No: T5S2283
Synonym:
Target: p38 MAPK, Caspase, JNK
Gypenoside L
Cat.No: TN1721
Synonym:
Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS
Hesperetin
Cat.No: T2565
Synonym: 橙皮素
Target: Apoptosis, p38 MAPK, 5-HT Receptor, Autophagy, TGF-beta/Smad
Esculin
Cat.No: T2885
Synonym: 秦皮甲素,马栗树皮甙,Aesculin
Target: Antiviral, p38 MAPK, Antibacterial
Dihydrocaffeic acid
Cat.No: T0539
Synonym: 二氢咖啡酸,Hydrocaffeic acid
Target: Antioxidant, p38 MAPK, Endogenous Metabolite
Isoliquiritin apioside
Cat.No: T3860
Synonym:
Target: MMP, p38 MAPK, NF-κB
5,6,7-TRIMETHOXYFLAVONE
Cat.No: T7051
Synonym: Baicalein Trimethyl Ether,黄岑素-5,6,7-三甲醚
Target: p38 MAPK
Dehydrocorydaline
Cat.No: T5S2358
Synonym: Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Rotundic acid
Cat.No: T5S0506
Synonym: Rutundic acid,铁冬青酸
Target: Apoptosis, Others, p38 MAPK, Akt, mTOR
N-​Feruloyloctopamine
Cat.No: TN1968
Synonym: N-Feruloyloctopamine,N-阿魏酰章鱼胺
Target: p38 MAPK, Akt
Kaempferol-3-O-glucorhamnoside
Cat.No: T5S0089
Synonym: Kaempferol 3-glucorhamnoside,百蕊草素I
Target: Antioxidant, p38 MAPK, NF-κB
Nitidine chloride
Cat.No: T5S0761
Synonym:
Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite
Dehydrocorydaline chloride
Cat.No: T10990
Synonym: 盐酸脱氢紫堇碱,13-Methylpalmatine chloride
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Cornuside
Cat.No: T4S2326
Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside
Target: ERK, p38 MAPK, NF-κB, JNK
Dehydrocorydaline nitrate
Cat.No: T2S2362
Synonym: 去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱
Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy
FERULIC ACID METHYL ESTER
Cat.No: TL0004
Synonym: 阿魏酸甲酯,Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate
Target: p38 MAPK, Autophagy
Butein
Cat.No: T6427
Synonym: 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因
Target: Apoptosis, EGFR, Others, PDE, Autophagy
Andrograpanin
Cat.No: T9218
Synonym: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE,新穿心莲内酯苷元
Target: p38 MAPK
Methacycline hydrochloride
Cat.No: T0518
Synonym: Rondomycin,盐酸甲烯土霉素,盐酸美他环素,Methacycline HCl
Target: ribosome, Antibacterial, Antibiotic
Skatole
Cat.No: T5281
Synonym: 粪臭素,Scatole,3-Methylindole,3-​Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole
Target: AhR, p38 MAPK, Aryl Hydrocarbon Receptor, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal
Rhoifolin
Cat.No: T2755
Synonym: 野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Paris saponin VII
Cat.No: T4085
Synonym: 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII
Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy
10-Gingerol
Cat.No: T3908
Synonym: 10-姜酚
Target: Apoptosis
Lucideric acid A
Cat.No: TN1879
Synonym: Lucidenic acid A,赤芝酸A
Target: MMP, p38 MAPK, JNK
Isoacteoside
Cat.No: T3892
Synonym: 异麦角甾苷,Isoverbascoside
Target: NF-κB
Asatone
Cat.No: T10383
Synonym:
Target: NF-κB
Imperatorin
Cat.No: T2845
Synonym: Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen
Target: TRP/TRPV Channel, AChR, AChE, NOD
Atractylenolide II
Cat.No: T5S0168
Synonym: 2-Atractylenolide,Asterolide,苍术内酯II
Target: Apoptosis, ERK, p38 MAPK, Akt, STAT
Sec-O-Glucosylhamaudol
Cat.No: T5S0581
Synonym: 亥茅酚苷,Hamaudol 3-glucoside
Target: Others, Opioid Receptor
Shanzhiside methyl ester
Cat.No: T3896
Synonym: 三栀子甙甲酯,山芝皂苷甲酯
Target: Glucagon Receptor
Velutin
Cat.No: T3816
Synonym:
Target: NF-κB, HIF/HIF Prolyl-Hydroxylase
Neoandrographolide
Cat.No: T3884
Synonym: Neoandrographiside,新穿心莲内酯
Target: NOS, COX
Lawsone methyl ether
Cat.No: T3008
Synonym: 2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone,2-甲氧基-1,4-萘并醌
Target: Apoptosis, Antibacterial, Antifungal
Triptonide
Cat.No: T5S1058
Synonym: 雷公藤内酯酮,PG 492,NSC 165677
Target: Apoptosis, Wnt/beta-catenin, Autophagy
Mulberroside A
Cat.No: T6S1597
Synonym: 桑皮苷 A,桑皮苷A
Target: TNF, Tyrosinase, Interleukin
Gossypetin
Cat.No: TN1711
Synonym:
Target: Antioxidant, p38 MAPK, MAPK, Antibacterial
Fumaric acid
Cat.No: T3763
Synonym: Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,反丁烯二酸,Donitic acid,Allomaleic acid,富马酸
Target: Endogenous Metabolite
Magnesium Lithospermate B
Cat.No: T20793
Synonym: 丹參酸B鎂,Monomethyl lithospermate B,丹参酸 B 镁,Lithospermate B
Target: Others
Aurantiamide
Cat.No: T5814
Synonym: TMC-58B,橙黄胡椒酰胺
Target: p38 MAPK, NF-κB
Saikosaponin A
Cat.No: T2768
Synonym: 柴胡皂苷A,柴胡皂苷 A
Target: NF-κB, Antibacterial, Liver X Receptor
anemarsaponin B
Cat.No: T7030
Synonym: 知母皂苷B,知母皂苷 B
Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase
Kamebakaurin
Cat.No: TWS1977
Synonym: 尾叶香茶菜丙素,Kamebakaurine
Target: NF-κB
Dihydrorotenone
Cat.No: TN1586
Synonym:
Target: Apoptosis, Mitochondrial Metabolism
Toddaculin
Cat.No: TN5888
Synonym:
Target: Others
Sesamol
Cat.No: T3676
Synonym: 1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol,芝麻酚
Target: Apoptosis, AMPK
Ethyl trans-caffeate
Cat.No: T3S0013
Synonym: 咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester
Target: Others
(-)-Bornyl acetate
Cat.No: TN1448
Synonym: L-(-)-Bornyl acetate,左旋乙酸冰片酯,Bornyl acetate,(-)-乙酸龙脑酯
Target: p38 MAPK, NF-κB, JNK, Antifungal
Calycosin
Cat.No: T3923
Synonym: Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮
Target: Apoptosis, Tyrosinase
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Cat. No. Product Name Species Expression System
TMPY-04260 p38 Protein, Human, Recombinant (His)

mitogen-activated protein kinase 14,CSPB1,PRKM14,RK,p38<...

Human Baculovirus Insect Cells
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK14 can be detected in the brain, heart, placenta, pancreas, and skeletal muscle and it is expressed to a lesser extent in the lung, liver, and kidney. MAPK14 is activated by various environmental stresses ...
TMPY-04430 p38 gamma/MAPK12 Protein, Human, Recombinant

mitogen-activated protein kinase 12,SAPK-3,P38 γ/MA...

Human Baculovirus Insect Cells
p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
TMPY-04551 p38 delta/MAPK13 Protein, Human, Recombinant (GST)

MAPK13,p38δ,PRKM13,MAPK-13,mitogen-activated protei...

Human Baculovirus Insect Cells
p38 delta/MAPK13 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPY-04429 p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)

ERK3,SAPK3,PRKM12,ERK6,P38γ,P38GAMMA,mitog...

Human Baculovirus Insect Cells
p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
TMPY-04531 p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro

P38 δ/MAPK13,MAPK13,PRKM13,MAPK-13,p38δ,

Human Baculovirus Insect Cells
p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPY-02844 EBP1 Protein, Human, Recombinant (His)

proliferation-associated 2G4,EBP1,p38-2G4,HG4-1

Human E. coli
EBP1, also known as PA2G4, is an RNA-binding protein that belongs to the peptidase M24 family. It can be detected n several cell lines tested, including primary and transformed cell lines. EBP1 also present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein is a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its int...
TMPH-00887 AHSA1 Protein, Human, Recombinant (GST)

C14orf3,p38,Activator of 90 kDa heat shock protein ...

Human E. coli
Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. AHSA1 Protein, Human, Recombinant (GST) is expressed i...
TMPH-00927 AIMP2 Protein, Human, Recombinant (His)

Protein JTV-1,Aminoacyl tRNA synthase complex-interacting mu...

Human E. coli
AIMP2 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-04539 ERK2 Protein, Human, Recombinant (GST)

ERT1,ERK,PRKM1,ERK-2,p41,p41mapk,PRKM2,ERK2,p40,p42-MAPK,MAP...

Human Baculovirus Insect Cells
ERK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 67 kDa and the accession number is P28482-1.
TMPY-05970 SARS-CoV-2 Spike RBD Protein (P384L, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike RBD Protein (P384L, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPH-00022 Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO)

Acinetobacter baumannii E. coli
Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor). Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.5 kDa and the accession number is A3M8K2.
TMPH-00021 Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His)

Acinetobacter baumannii P. pastoris (Yeast)
Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor).
TMPY-03885 Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)

AD1,AAA,ABETA,CVAP,PN-II,CTFgamma,Aβ,APPI,PN2,CTFγ,β-amyloid...

Human E. coli
Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.1 kDa and the accession number is P05067-1.
TMPH-00023 Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc)

Acinetobacter baumannii E. coli
Functions as a porin. Induces apoptosis in human cell lines through caspase-dependent and AIF-dependent pathways. Purified Omp38 enters host cell and localizes to the mitochondria, which presumably leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor). Binds peptidoglycan, contributes to cell wall maintenance (Probable). Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc) is expressed in E. coli expression system with N-1...
TMPY-05176 AMH Protein, Human, Recombinant (His)

MIS,anti-Mullerian hormone,MIF

Human HEK293 Cells
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi...
TMPY-04572 MKK4 Protein, Mouse, Recombinant (His & GST)

MKK4,MEK4,PRKMK4,Sek1,JNKK1,Serk1,mitogen-activated protein ...

Mouse Baculovirus Insect Cells
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is a protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K4 / JNKK1 is a protein kinase that is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. MAP2K4 / ...
TMPH-01251 DUSP26 Protein, Human, Recombinant (His & SUMO)

MKP-8,NATA1,DSP-4,SKRP3,DUSP26,MKP8,LDP-4,LDP4,DUSP24,Dual s...

Human E. coli
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
TMPY-04425 PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)

PRAK,MAPKAP-K5,MK-5,mitogen-activated protein kinase-activat...

Human Baculovirus Insect Cells
MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK). It is widely distributed. MAPKAPK5 can be phosphorylated by an extracellular-regulated kinase (ERK), and p38 kinase but not by c-jun N-terminal kinase (JNK)in vitro. Recombinant GST-MAPKAPK5 protein can phosphorylate a peptide derived from the regulator...
TMPK-00696 PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)

MAPKAPK5,MK5,MAPKAP-K5,MK-5,MAPKAPK-5

Human Baculovirus Insect Cells
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway.
TMPJ-01456 Mucin-17/MUC17 Protein, Human, Recombinant (His)

Mucin-17, MUC-17, MUC17, MUC3, MUC-3

Human HEK293 Cells
Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression ...
TMPY-03655 GADD45G Protein, Human, Recombinant

GADD45γ,growth arrest and DNA-damage-inducible, γ,DDIT2,grow...

Human E. coli
GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G reacts to environmental stresses by mediating activation of the p38/JNK pathway which is mediated through their protein binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. GADD45G acts as a new-age tumor suppressor however is being fr...
TMPY-04378 MAPKAPK3 Protein, Human, Recombinant (GST)

mitogen-activated protein kinase-activated protein kinase 3,...

Human Baculovirus Insect Cells
The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identified and serve as substrates for the ERK and p38 MAP kinases. Mitogen-activated protein (MAP) kinase-activated protein kinase 3, also known as MAPKAPK-3 and 3pK, is a member of the Ser/Thr protein kinase family. It is widely expressed in hu...
TMPH-01250 MAP2K3 Protein, Human, Recombinant (His & SUMO)

Human E. coli
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. MAP2K3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.3 kDa and the accession numbe...
TMPH-01001 BCL10 Protein, Human, Recombinant (His & SUMO)

B-cell lymphoma/leukemia 10,cCARMEN,hCLAP,CIPER,CLAP,BCL10,B...

Human E. coli
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation. Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing proteins CARD9, CARD11 and CARD14 to activate NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Recruited by activated CARD domain-containing proteins: homooligome...
TMPJ-00711 GADD45G Protein, Human, Recombinant (His)

Cytokine-Responsive Protein CR6,Growth Arrest and DNA Damage...

Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. GADD45G is also involved in the regulation of growth and apo...
TMPJ-00907 GADD45A Protein, Human, Recombinant (His)

GADD45,DDIT1,Growth Arrest and DNA Damage-Inducible Protein ...

Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating ...
TMPJ-00700 GADD45B Protein, Human, Recombinant (His)

MYD118,Myeloid Differentiation Primary Response Protein MyD1...

Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of growth and apoptosis. GADD45B reacts to environmental stresses by mediating activation of stress-responsive MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. In addition, GADD45B participates in the down-regulation of hepatocellular carcinoma (HCC). It m...
TMPY-03976 EEF1E1 Protein, Human, Recombinant (His)

eukaryotic translation elongation factor 1 ε 1,P18,eukaryoti...

Human E. coli
EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. It is comprised of a bifunctional glutamyl-prolyl-tRNA synthase, the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl and aspartyl-tRNA synthases, and three auxiliary proteins, EEF1E1/p18, AIMP2/p38 and AIMP1/p43. EEF1E1 also plays a positive role in ATM/AT...
TMPJ-01433 Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated

Fibronectin,FN1

Human E. coli
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, an...
TMPY-02444 ATF2 Protein, Human, Recombinant (His & GST)

CREB2,CRE-BP1,CREB-2,TREB7,activating transcription factor 2...

Human Baculovirus Insect Cells
Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has ...
TMPJ-00674 RANK/TNFRSF11A Protein, Mouse, Recombinant (His)

Receptor activator of NF-KB,TNFRSF11A,Osteoclast differentia...

Mouse HEK293 Cells
Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, br...
TMPY-04547 PBK/TOPK Protein, Human, Recombinant (His)

HEL164,Nori-3,CT84,TOPK,PDZ binding kinase,SPK

Human Baculovirus Insect Cells
PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the characteristic protein kinase subdomains and a C-terminal PDZ-binding T/SXV motif. PBK is expressed in the testis restrictedly expressed in outer cell layer of seminiferous tubules, as well as placenta. PBK may be enrolled in the activation of lymphoid cells and support testicular fun...
TMPY-04374 MST4 Protein, Human, Recombinant (GST)

serine/threonine protein kinase 26,MST4,MASK

Human Baculovirus Insect Cells
MST4, also known as mammalian STE2-like protein kinase 4, is a novel member of the germinal center kinase subfamily of human Ste2-like kinases and is closely related to MST3. The 416 amino acid full-length MST4 contains a C-terminal regulatory domain and an N-terminal kinase domain, both of which are required for full activation of the kinase. MST4 is highly expressed in the placenta, thymus, and peripheral blood leukocytes. MST4 specifically activates ERK but not JNK or p38 MAPK in transiently ...
TMPY-01033 IL-32 Protein, Human, Recombinant (isoform alpha, His)

IL-32δ,IL-32beta,IL32,TAIFc,IL-32γ,白介素,IL-32 Protein(isoform...

Human HEK293 Cells
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,...
TMPY-04460 OXSR1 Protein, Human, Recombinant (GST)

OSR1,oxidative stress responsive 1

Human Baculovirus Insect Cells
Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. OXSR1 is a 58 kDa protein of 527 amino acids that is widely expressed in mammalian tissues and cell lines. The amino acid (aa) sequence of the predicted OXSR1 protein is 39% identical to that of human SOK1. Of...
TMPJ-00060 IL-25/IL17E Protein, Human, Recombinant (His)

白细胞介素,IL17E,白介素,IL-17E,IL-25,IL25,Interleukin-25,Interleukin...

Human HEK293 Cells
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator...
TMPY-04391 Lyn Protein, Human, Recombinant (GST)

JTK8,LYN proto-oncogene, Src family tyrosine kinase,p56Lyn,p...

Human Baculovirus Insect Cells
Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between prolif...
TMPY-02191 BLNK Protein, Human, Recombinant (His)

BLNK-S,bca,SLP-65,B-cell linker,LY57,SLP65,AGM4,BASH

Human HEK293 Cells
B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65 and BLNK, is a cytoplasm and cell membrane protein which contains oneSH2 domain. BLNK is expressed in B-cell lineage and fibroblast cell lines. Highest levels of expression is in the spleen, with lower levels in the liver, kidney, pancreas, small inte...

重组蛋白

p38 Protein, Human, Recombinant (His)
Cat.No: TMPY-04260
Species: Human
Expression System: Baculovirus Insect Cells
p38 gamma/MAPK12 Protein, Human, Recombinant
Cat.No: TMPY-04430
Species: Human
Expression System: Baculovirus Insect Cells
p38 delta/MAPK13 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04551
Species: Human
Expression System: Baculovirus Insect Cells
p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04429
Species: Human
Expression System: Baculovirus Insect Cells
p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro
Cat.No: TMPY-04531
Species: Human
Expression System: Baculovirus Insect Cells
EBP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02844
Species: Human
Expression System: E. coli
AHSA1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-00887
Species: Human
Expression System: E. coli
AIMP2 Protein, Human, Recombinant (His)
Cat.No: TMPH-00927
Species: Human
Expression System: E. coli
ERK2 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04539
Species: Human
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike RBD Protein (P384L, His)
Cat.No: TMPY-05970
Species: SARS-CoV-2
Expression System: HEK293 Cells
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO)
Cat.No: TMPH-00022
Species: Acinetobacter baumannii
Expression System: E. coli
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His)
Cat.No: TMPH-00021
Species: Acinetobacter baumannii
Expression System: P. pastoris (Yeast)
Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)
Cat.No: TMPY-03885
Species: Human
Expression System: E. coli
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc)
Cat.No: TMPH-00023
Species: Acinetobacter baumannii
Expression System: E. coli
AMH Protein, Human, Recombinant (His)
Cat.No: TMPY-05176
Species: Human
Expression System: HEK293 Cells
MKK4 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-04572
Species: Mouse
Expression System: Baculovirus Insect Cells
DUSP26 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01251
Species: Human
Expression System: E. coli
PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04425
Species: Human
Expression System: Baculovirus Insect Cells
PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)
Cat.No: TMPK-00696
Species: Human
Expression System: Baculovirus Insect Cells
Mucin-17/MUC17 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01456
Species: Human
Expression System: HEK293 Cells
GADD45G Protein, Human, Recombinant
Cat.No: TMPY-03655
Species: Human
Expression System: E. coli
MAPKAPK3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04378
Species: Human
Expression System: Baculovirus Insect Cells
MAP2K3 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01250
Species: Human
Expression System: E. coli
BCL10 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01001
Species: Human
Expression System: E. coli
GADD45G Protein, Human, Recombinant (His)
Cat.No: TMPJ-00711
Species: Human
Expression System: E. coli
GADD45A Protein, Human, Recombinant (His)
Cat.No: TMPJ-00907
Species: Human
Expression System: E. coli
GADD45B Protein, Human, Recombinant (His)
Cat.No: TMPJ-00700
Species: Human
Expression System: E. coli
EEF1E1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03976
Species: Human
Expression System: E. coli
Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated
Cat.No: TMPJ-01433
Species: Human
Expression System: E. coli
ATF2 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02444
Species: Human
Expression System: Baculovirus Insect Cells
RANK/TNFRSF11A Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00674
Species: Mouse
Expression System: HEK293 Cells
PBK/TOPK Protein, Human, Recombinant (His)
Cat.No: TMPY-04547
Species: Human
Expression System: Baculovirus Insect Cells
MST4 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04374
Species: Human
Expression System: Baculovirus Insect Cells
IL-32 Protein, Human, Recombinant (isoform alpha, His)
Cat.No: TMPY-01033
Species: Human
Expression System: HEK293 Cells
OXSR1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04460
Species: Human
Expression System: Baculovirus Insect Cells
IL-25/IL17E Protein, Human, Recombinant (His)
Cat.No: TMPJ-00060
Species: Human
Expression System: HEK293 Cells
Lyn Protein, Human, Recombinant (GST)
Cat.No: TMPY-04391
Species: Human
Expression System: Baculovirus Insect Cells
BLNK Protein, Human, Recombinant (His)
Cat.No: TMPY-02191
Species: Human
Expression System: HEK293 Cells
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