280
36
35
15
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T40545 |
MES
2-Morpholinoethanesulphonic acid,4-Morpholineethanesulfonic acid |
Others | Others |
MES (2-Morpholinoethanesulphonic acid) (2-Morpholinoethanesulphonic acid) 是一种两性离子缓冲液,在 pH 值 5.5-7.7 范围内有效。MES 作为一种 Good's 缓冲液,广泛应用于植物培养基、试剂溶液和生理实验中调节 pH 值。 | |||
T65287 |
MES monohydrate
|
Others | Others |
MES monohydrate 是一种两性离子缓冲液,是一种 PH 稳定试剂,可用于蛋白质纯化和酶测定。 | |||
T40819 |
MES sodium salt
2-Morpholinoethanesulphonic acid sodium salt |
Others | Others |
MES (2-Morpholinoethanesulphonic acid) sodium salt, a zwitterionic buffer, is effective in the pH range of 5.5-7.7. MES sodium salt, as one of the Good’s buffers, is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments. | |||
T24975 |
2MeSAMP
2 MeS AMP bis-sodium,2-MeS-AMP bis-sodium,2MeSAMP bis-sodium |
Others | Others |
2MeSAMP is a P2Y(12) antagonist that works by inhibiting platelet activation through a P2Y(12)/G(i)-dependent mechanism. | |||
T23581 |
2-Methylthioadenosine diphosphate trisodium
2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP |
Others | Others |
2-MeS-ADP is a purinergic agonist that acts by displaying selectivity for P2Y1, P2Y12, and P2Y13 receptors and inhibiting cAMP accumulation. | |||
T65286 |
MES hemisodium salt
|
Others | Others |
MES hemisodium salt 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65286,CAS号为 117961-21-4。 | |||
T7780 |
Blarcamesine
AE-37,AVex-73 |
AChR | Neuroscience |
Blarcamesine (AVex-73) 是一种毒蕈碱 M1 激动剂,具有抗惊厥、抗失忆、神经保护和抗抑郁的特性,可能用于治疗阿尔茨海默病。 | |||
T8544 |
Masitinib mesylate
甲磺酸马赛替尼,AB-1010 mesylate,马赛替尼 |
Apoptosis; FAK; FGFR; PDGFR; Src; c-Kit | Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Masitinib mesylate (AB-1010 mesylate) 是一种生物口服可利用的选择性 c-Kit 抑制剂,IC50 为 200 nM。它还抑制 PDGFRα/β,IC50值为540/800 nM,对 LynB 的 IC50为510 nM。它的毒性低,有抗增殖和促凋亡活性。 | |||
T6978 |
Almitrine mesylate
Almitrine dimesylate,甲磺酸阿米三嗪,Almitrine bismethanesulfonate,Almitrine bismesylate |
Potassium Channel | Membrane transporter/Ion channel |
Almitrine mesylate (Almitrine dimesylate) 是外周化学感受器激动剂,对Ca2+依赖性的K+通道具有选择性抑制作用。 | |||
T1518 |
Olmesartan Medoxomil
奥美沙坦酯,CS 866,Benicar |
RAAS | Endocrinology/Hormones |
Olmesartan Medoxomil (Benicar) 是血管紧张素 (angiotensin AT1) 受体选择性抑制剂(IC50:66.2 μM)。 | |||
T12678 |
(Rac)-Telmesteine
替美司坦,3-(Ethoxycarbonyl)thiazolidine-4-carboxylic acid,3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid,3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester |
Protease | Proteases/Proteasome |
(Rac)-Telmesteine (3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester) 是蛋白酶抑制剂,可用作含蛋白酶的洗涤剂和清洗剂中的酶稳定剂。 | |||
T3597 |
Cutamesine dihydrochloride
AGY94806 dihydrochloride,库他美新二盐酸盐,SA4503 (dihydrochloride),SA4503 dihydrochloride |
Sigma receptor | GPCR/G Protein |
Cutamesine dihydrochloride (SA4503 dihydrochloride) 是一种选择性 σ1 受体激动剂,IC50值为 17.4 nM。 | |||
T9789 |
Cevidoplenib dimesylate hydrochloride
|
Syk | Angiogenesis; Tyrosine Kinase/Adaptors |
Cevidoplenib dimesylate hydrochloride 是一种脾酪氨酸激酶 (Syk) 抑制剂,具有潜在的免疫调节和抗炎特性。 | |||
T7112 |
Ibutamoren Mesylate
MK-0677,伊布莫仑甲磺酸盐,MK-677 |
GHSR | GPCR/G Protein |
Ibutamoren Mesylate (MK-0677) 是非肽段类生长激素促分泌素受体 (GHSR) 激动剂,也是一种口服有活性的生长激素 (GH) 促分泌素。 | |||
T7804 |
Garenoxacin mesylate hydrate
Garenoxacin mesylate [USAN],加雷沙星甲磺酸盐,BMS284756 (Mesylate hydrate) |
Antibacterial | Microbiology/Virology |
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) 是一种新型口服 des-fluoro(6) 喹诺酮,具有强抗菌活性,抗呼吸道病原体。 | |||
T4342 |
PF-04929113 Mesylate
PF-04929113 (Mesylate),SNX-5422 Mesylate |
HSP; HER | Angiogenesis; Cytoskeletal Signaling; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors |
PF-04929113 Mesylate (SNX-5422 Mesylate) 是 SNX-2112 的前药,是一种可口服的 Hsp90 抑制剂 (Kd: 41 nM),还可诱导 Her-2 降解 (IC50: 37 nM)。 | |||
T4983 |
Isoetharine mesylate salt
Isoetarine mesilate,异丙肾上腺素甲磺酸盐 |
Others; Adrenergic Receptor | GPCR/G Protein; Neuroscience; Others |
Isoetharine mesylate salt (Isoetarine mesilate) 是一种 β-肾上腺素能受体激动剂。它还是能够上调 CYP450 表达的孕烷 X 受体(PXR) 激活剂。 | |||
T0101 |
Doxazosin mesylate
UK 33274 mesylate,甲磺酸多沙唑嗪 |
Mitophagy; Adrenergic Receptor; Autophagy | Autophagy; GPCR/G Protein; Neuroscience |
Doxazosin mesylate (UK 33274 mesylate) 是一种喹唑啉衍生物。它是一种选择性拮抗突触后α1-肾上腺素能受体。 | |||
T5133 |
Dabigatran Etexilate Mesylate
甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate |
Thrombin | Proteases/Proteasome |
Dabigatran Etexilate Mesylate (BIBR 1048MS) 是一种口服具有活性的 Dabigatran 前药,具有抗凝作用,能够预防心房颤动引起的静脉血栓栓塞和中风。 | |||
T9173 |
HM-30181 mesylate monohydrate
|
P-gp | Membrane transporter/Ion channel; Neuroscience |
HM-30181 mesylate monohydrate 是一种口服 P-糖蛋白 (P-gp) 抑制剂,用于提高 P-gp 底物药物的口服生物利用度。 | |||
T13564L2 |
AZ7550 trimesylate salt
AZ7550 Mesylate,AZ7550 trimesylate salt (1421373-99-0 free base) |
MLK | MAPK |
AZ7550 trimesylate salt (AZ7550 Mesylate) 是奥希替尼的活性代谢产物,AZ7550 trimesylate salt 抑制 IGF1R 活性,可用于研究非小细胞肺癌。 | |||
T2617 |
SNS-314 Mesylate
SNS-314 |
Aurora Kinase | Cell Cycle/Checkpoint; Chromatin/Epigenetic |
SNS-314 Mesylate (SNS-314) 是一种有效且特异性的极光激酶抑制剂,对极光激酶 A、B、C 的 IC50值分别为 9,31 和 3 nM。 | |||
T71708 |
Minamestane
|
Aromatase | Endocrinology/Hormones |
Minamestane 是一种新型不可逆芳香化酶抑制剂。Minamestane 引起人胎盘芳香化酶的时间依赖性抑制,半衰期为4分钟,K 为59nM。Minamestane 具有抗肿瘤活性。 | |||
T1579 |
Mestranol
Devocin,Norquen,美雌醇,Menophase |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Mestranol (Devocin) 是一种雌激素受体激动剂,是一种非活性的前药,在转化为炔雌醇时具有生物活性。动物实验中,它可以与黄体酮联合使用,它可用于更年期激素或月经紊乱的研究。 | |||
T1621 |
Imatinib Mesylate
甲磺酸伊马替尼,ST-1571 Mesylate,STI-571,CGP-57148B |
Bcr-Abl; PDGFR; c-Kit; Autophagy | Angiogenesis; Autophagy; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Imatinib Mesylate (STI571 Mesylate) 是一种多靶点受体酪氨酸激酶抑制剂,可选择性抑制 BCR/ABL、v-Abl、PDGFR、c-kit 等激酶活性,具有口服活性。Imatinib Mesylate 具有抗肿瘤活性,可用于治疗慢性粒细胞白血病。 | |||
T10759 |
CEP-28122 mesylate salt (1022958-60-6 free base)
CEP-28122 mesylate salt |
ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
CEP-28122 mesylate salt (1022958-60-6 free base) 是一种高选择性的口服活性 ALK 抑制剂(在基于酶的 TRF 测定中,IC50:1.9 nM)。 | |||
T3634 |
Osimertinib mesylate
甲磺酸奥希替尼,Mereletinib mesylate,奥希替尼甲磺酸盐,AZD-9291 mesylate |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Osimertinib mesylate (Mereletinib mesylate) 是一种不可逆的突变选择性 EGFR 抑制剂,对EGFRL858R 和EGFRL858R/T790M 的IC50值分别为 12 和 1 nM。 | |||
T72528 |
NSC243928 mesylate
|
HuR | Chromatin/Epigenetic |
NSC243928 mesylate 可与人类淋巴细胞抗原 6 (LY6) 结合,是细胞生长抑制剂,具有抗癌活性,以 LY6K 依赖性方式诱导三阴性乳腺癌细胞的细胞死亡。 | |||
T15675 |
Tirbanibulin Mesylate
KX2-391 Mesylate,KX01 Mesylate |
Microtubule Associated; Src | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Tirbanibulin Mesylate (KX01 Mesylate) 是一种 Src 抑制剂,靶向 Src 的肽底物位点。在肿瘤细胞中,GI50值为 9-60 nM。 | |||
T26834 |
BL-1020 Mesylate
CYP-1020 Mesylate |
Dopamine Receptor; GABA Receptor | GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
BL-1020 Mesylate (CYP-1020 Mesylate) 是一种可口服的 GABA A 受体激动剂和 D2 拮抗剂,可降低多巴胺活性并增强GABAA活性。BL-1020 Mesylate 可用于研究神经分裂、阿尔茨海默症和双向认知障碍。 | |||
T13687 |
Eribulin mesylate
B1939 mesylate,甲磺酸艾日布林,ER-086526 mesylate,E7389 mesylate |
Apoptosis; Others; Microtubule Associated | Apoptosis; Cytoskeletal Signaling; Others |
Eribulin mesylate (E7389 mesylate) 是一种靶向微管的抗癌剂,通过结合微管蛋白和微管来抑制癌细胞的增殖,可研究转移性乳腺癌。 | |||
T4042 |
Talabostat mesylate
Val-boroPro,PT100 |
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Talabostat mesylate (PT100) 是一种具有口服活性和非选择性的二肽基肽酶 IV 抑制剂(IC50< 4 nM;Ki= 0.18 nM)。Talabostat mesylate 是成纤维细胞活化蛋白的第一个临床抑制剂(IC50= 560 nM),抑制 DPP8/9 (IC50= 4/11 nM;Ki= 1.5/0.76 nM),静息细胞脯氨酸二肽酶(IC50= 310 nM)、DPP2 和一些其他 DASH 家族酶。Talabostat mesylate 具有抗肿瘤和造血刺激活性 。 | |||
T11949 |
Masupirdine mesylate
SUVN-502 mesylate,SVN-502 mesylate |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Masupirdine mesylate (SUVN-502 mesylate) 是一种具有选择性且可穿越血脑屏障的 5-HT6 受体拮抗剂。Masupirdine mesylate 可用于研究阿尔茨海默病和痴呆等神经系统疾病。 | |||
T28020 |
Mesendogen
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
Mesendogen 是瞬时受体电位阳离子通道、亚家族 M、成员 6 (TRPM6) 和 7 (TRPM7) 的抑制剂,通过抑制 TRPM6/TRPM7 镁通道活性起作用。 | |||
T2391 |
Camostat mesylate
FOY-S980,甲磺酸卡莫司他,FOY305,Camostat mesilate |
Serine/threonin kinase; SARS-CoV; Sodium Channel | Cell Cycle/Checkpoint; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology |
Camostat mesylate (FOY-S980) 是口服活性合成的丝氨酸蛋白酶抑制剂,用于慢性胰腺炎。它是TMPRSS2的抑制剂,对SARS-CoV-2具有抗病毒活性。它抑制前列腺素、胰蛋白酶和苦参多糖的活性。 | |||
T6047 |
Ralimetinib dimesylate
LY2228820 dimesylate,Ralimetinib,LY2228820,Ralimetinib Mesylate |
Apoptosis; p38 MAPK; Autophagy | Apoptosis; Autophagy; MAPK |
Ralimetinib dimesylate (LY2228820 dimesylate) 是一种选择性,ATP 竞争性的 p38 MAPK α/β抑制剂,IC50分别为5.3 和 3.2 nM。 | |||
T6651 |
Safinamide mesylate
PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate,沙芬酰胺甲磺酸盐 |
MAO; Monoamine Oxidase | Metabolism; Neuroscience |
Safinamide mesylate (EMD 1195686 mesylate) 是选择性的、有效的、可逆的单胺氧化酶 B 的抑制剂,对 MAO-A 选择性较低。它能够阻断钠通道和调节谷氨酸释放。它具有神经保护作用,可用于研究帕金森病、缺血脑卒中等疾病。 | |||
T8474 |
Dabrafenib Mesylate
达帕菲尼甲磺酸盐,甲磺酸达拉非尼,GSK 2118436B,GSK2118436 Mesylate |
Raf | MAPK |
Dabrafenib Mesylate (GSK2118436 Mesylate) 是一种ATP 竞争型Raf 抑制剂,抑制C-Raf 和B-RafV600E 的IC50分别为 5 和 0.6 nM。 | |||
T14526 |
Bemesetron
TROPANYL 3,5-DICHLOROBENZOATE,3-TROPANYL-3,5-DICHLOROBENZOATE,贝美司琼,MDL 72222 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Bemesetron (MDL 72222) 是 5-HT3 的选择性拮抗剂 (IC50 = 0.33 nM),具有神经保护作用。 | |||
T0425L |
Pefloxacin Mesylate Dihydrate
Pefloxacinium mesylate dihydrate,1589 RB,甲磺酸培氟沙星二水合物 |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Pefloxacin Mesylate Dihydrate (1589 RB) 是一种抗菌素,能通过抑制DNA 旋转酶阻断细菌DNA 复制。 | |||
T61150 |
Oleyl Mesylate
|
Others | Others |
Oleyl Mesylate 是可以掺入各种制剂中的油醇的衍生物。 | |||
T8377 |
Mesotrione
甲基磺草酮,硝磺草酮 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Mesotrione 是一种苯甲酰环己二酮类除草剂,是一种竞争性羟基苯基丙酮酸双加氧酶酶抑制剂。它对玉米作物具有选择性,它在易感作物中代谢速度快,耐受性较高。 | |||
T1536 |
Promestriene
3-propyl ethyl,舒经劳,17B-methyl estradiol,Promestriano |
Estrogen/progestogen Receptor | Endocrinology/Hormones |
Promestriene (3-propyl ethyl) 是局部有效的雌激素,是合成的雌二醇二乙醚。它对阴道萎缩有作用,但吸收量小。 | |||
T4111 |
Blarcamesine hydrochloride
Anavex 2-73,AVex-73 hydrochloride,AE-37 hydrochloride |
Sigma receptor | GPCR/G Protein |
Blarcamesine hydrochloride (AVex-73 hydrochloride) 是一个sigma-1受体激动剂,IC50值为 860 nM。 | |||
T19526 |
Pradefovir mesylate
Pradefovir mesilate,Remofovir mesylate,Hepavir B,甲磺酸帕拉德福韦 |
P450 | Metabolism |
Pradefovir mesylate (Hepavir B) 是一种肝脏 CYP3A4 底物。在人肝微粒体中,Pradefovir 能够转化为 9-[2-(磷酸甲氧基)乙基]腺嘌呤,其Km=60 μM。 | |||
T6962 |
Rasagiline Mesylate
TVP1012,甲磺酸雷沙吉兰,AGN1135,Azilect |
Apoptosis; MAO; Autophagy; Monoamine Oxidase | Apoptosis; Autophagy; Metabolism; Neuroscience |
Rasagiline Mesylate (AGN1135) 是一种高效的,不可逆的选择性线粒体单胺氧化酶 (MAO) 抑制剂,抑制大鼠脑 MAO B 和 MAO A 的IC50分别为 4.43 nM 和 412 nM。 | |||
T9409 |
Mesdopetam hemitartrate
IRL790 hemitartrate,1-Propanamine, N-[2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Mesdopetam hemitartrate (IRL790 hemitartrate) 是一种多巴胺D3受体拮抗剂 (Ki=90 nM;IC50=9.8 μM),具有稳定精神运动的作用,可用于帕金森病的运动和精神并发症的研究。 | |||
T11043 |
Dihydroergocristine mesylate
甲磺酸双氢麦角汀,DHEC (mesylate) |
Beta Amyloid | Neuroscience |
Dihydroergocristine mesylate (DHEC (mesylate)) 是一种 γ-secretase (GSI) 的抑制剂,能够阿尔茨海默氏病淀粉样蛋白 β 肽 (amyloid-β) 的产生,与 γ-secretase 和 Nicastrin 结合的平衡解离常数 (Kd) 值分别为 25.7 nM 和 9.8 μM。 | |||
T38521 |
Patamostat mesylate
E 3123 mesylate,E-3123 mesylate,E3123 mesylate |
Apoptosis; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
Patamostat (E-3123) mesylate 是一种组蛋白去乙酰化酶(HDAC)抑制剂。Patamostat mesylate 增加乙酰化的组蛋白和微管蛋白在肿瘤细胞中积累,促使细胞周期终止和细胞凋亡。Patamostat mesylate具有抗肿瘤活性,可用于研究多发性骨髓瘤。 | |||
T6835 |
Fenoldopam mesylate
Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐 |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Fenoldopam mesylate (Corlopam mesylate) 是一种多巴胺受体D1选择性激动剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7938 |
Quinidine
奎尼丁,奎宁树 |
Parasite | Microbiology/Virology |
Quinidine 是一种抗心律失常剂,也是 K+通道的有效阻断剂,其 IC50值为 19.9 μM。它是一种选择性细胞色素 P450db 的有效抑制剂,也可研究疟疾。 | |||
T8125 |
Quinidine sulfate dihydrate
硫酸奎尼宁,硫酸奎尼丁二水合物,Chinidin Sodium,β-quinine Sodium,Pitayine Sodium,Quinidine sulfate |
P450 | Metabolism |
Quinidine sulfate dihydrate (Pitayine Sodium) 是抗心律失常剂,能够阻断 K+通道(IC50:19.9 μM)。它是细胞色素 P450db 的选择性抑制剂,可用于研究疟疾。 | |||
TMS0418 |
Dihydroergotoxine mesylate
甲磺酸二氢麦角碱,Ergoloid mesylates,甲磺酸双氢麦角毒碱 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Dihydroergotoxine mesylate (Ergoloid mesylates) 是系列生物碱盐混合物,对GABAA 受体高结合活性。它主要用于改善与衰老相关的精神退化的症状和身体症状。 | |||
T20880 |
Mesaconic acid
中康酸,Methylfumaric acid,Mesaconate,Kyselina mesakonova |
Others | Others |
Mesaconic acid (Methylfumaric acid) 被用作阻燃剂,因为最近的研究表明这种酸是富马酸盐还原的竞争性抑制剂。 | |||
T6S0627 |
Mesaconitine
新乌碱,新乌头碱;中乌头碱 |
TNF | Apoptosis |
Mesaconitine 是乌头属植物的一种主要活性成分,通过循环 AMP 和刺激中枢 β-肾上腺素能系统具有镇痛活性,还有抗炎活性。 | |||
TN1923 |
Mesaconine
|
IL Receptor; NF-κB | Immunology/Inflammation; NF-κB |
Mesaconine 是来自 Aconitum carmichaelii Debx 的一种成分。Mesaconine 具有心脏作用和抗 NF-κB 活性。 Mesaconine 可能是麻黄附子细辛汤抗炎和免疫抑制的部分物质基础。 | |||
T1276 |
Danofloxacin mesylate
甲磺酸达氟沙星,CP 76136-27 |
DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Danofloxacin mesylate (CP 76136-27) 是一种兽医用氟喹诺酮类抗菌素。 | |||
T0583 |
meso-Erythritol
赤藓糖醇,Erythrit,Erythritol,Phycitol |
Endogenous Metabolite | Metabolism |
meso-Erythritol (Phycitol) 是一种天然存在于各种食物 (如梨,西瓜等)的糖醇,其甜度为蔗糖的 60-80%,是一种经过批准的低热量甜味剂。 | |||
T5759 |
S-(+)-Marmesin
(+)-Marmesin,异紫花前胡内酯,(S)-Marmesin,marmesin |
Lipoxygenase; COX | Immunology/Inflammation; Metabolism; Neuroscience |
S-(+)-Marmesin (marmesin) 是一种从木橘成熟树皮中分离得到的香豆素,具有 COX-2/5-LOX 双重抑制活性。 | |||
T4914 |
Mesoxalate sodium (monohydrate)
Sodium mesoxalate monohydrate,丙酮二酸钠 |
Others; Endogenous Metabolite | Metabolism; Others |
Mesoxalate sodium (monohydrate) 是内源性代谢产物的一种。 | |||
T12564 |
Prudomestin
3,5,7-Trihydroxy-4',8-dimethoxyflavone,3,5,7-三羟基-8,4'-二甲氧基黄酮 |
Xanthine Oxidase | Metabolism |
Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) 是一种分离自 Prunus domestica 心材中,具有很强的黄嘌呤氧化酶(XO)抑制活性(IC50≈6 µM)。 | |||
T6S1885 |
Benzoylmesaconine
Mesaconine 14-benzoate,苯甲酰新乌头原碱 |
Others | Others |
Benzoylmesaconine (Mesaconine 14-benzoate) 是乌头汤最丰富的组分。其中乌头汤可用于研究类风湿性关节炎。 | |||
TQ0295 |
Coumestrol
拟雌内酯,考迈斯托醇 |
Estrogen Receptor/ERR | Endocrinology/Hormones |
Coumestrol 是一种大豆产品中存在的植物雌激素。它抑制ES2细胞增殖的IC50值为50 μM。它可用于癌症,神经障碍和自身免疫疾病的研究。 | |||
T13739 |
Isopropylidenylacetyl-marmesin
异紫花前胡内酯异戊烯酸酯,(±)-Prantschimgin,Prantschimgin |
Others | Others |
Isopropylidenylacetyl-marmesin (Prantschimgin) 是一种源自羌活 Notopterygium incisum 和 Ferulago bracteata 根的天然产物。 | |||
T28021 |
meso-Dihydroguaiaretic acid
|
||
meso-Dihydroguaiaretic acid is an LXR-α antagonist, it inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells. | |||
T126055 |
Marmesin angelate
|
Others | Others |
Marmesin angelate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126055。 | |||
TN1380 |
Marmesinin
Ammijin,印度榅桲甙 |
Others | Others |
Marmesinin是一种天然产物,属于伞形科阿米芹属,其产品编号为 TN1380,CAS号为 495-30-7。Marmesinin可用作对照参考。 | |||
TN5883 |
4'-O-Methylcoumestrol
4'-O-甲基香豆雌酚,9-O-Methylcoumestrol |
||
4'-O-Methylcoumestrol is a natural product from Glycyrrhiza pallidiflora Maxim. | |||
TN6358 |
meso-Hannokinol
|
||
meso-Hannokinol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6358,CAS号为 79055-11-1。 | |||
T126194 |
9-Hydroxyjasmesoside"
|
Others | Others |
9-Hydroxyjasmesoside" 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126194,CAS号为 121979-17-7。 | |||
TN6480 |
Benzoylmesaconine hydrochloride
|
||
Benzoylmesaconine hydrochloride has used as the reference standard to evaluate the quality of processed aconite root and powdered processed aconite root. | |||
T73857 |
Mesembrine
|
Others | Others |
Mesembrine ((+)-Mesembrine) 一种主要的生物碱,具有芳基八氢吲哚骨架。Mesembrine 是一种5-HT 转运蛋白抑制剂,Ki 为 1.4 nM。Mesembrine 还抑制磷酸二酯酶 4B (PDE4B),IC50为 7.8 μM。 | |||
T26369 |
(+/-)-Marmesin
Marmesin,(S)-Marmesin |
Others | Others |
Marmesin is a novel angiogenesis inhibitor. | |||
TN6806 |
Mesuagin
|
||
Mesuagin is a natural product. | |||
T125118 |
2',3'-Dehydromarmesin
|
Others | Others |
2',3'-Dehydromarmesin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125118。 | |||
TN4519 |
Mesuaxanthone A
胡桐,海棠木 |
Others | Others |
Mesuaxanthone A and mesuaxanthone B are two yellow pigments.They produce varying degrees of C.N.S. depression characterised by ptosis, sedation, decreased spontaneous motor activity, loss of muscle tone, potentiation of pentobarbitone sleeping time and et | |||
T28019 |
(-)-Mesembrine
Mesembrin,Mesembrine,Mesembranone |
Others | Others |
Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4). | |||
T83450 |
14-Benzoylmesaconine-8-palmitate
|
||
14-Benzoylmesaconine-8-palmitate(化合物4)为A. toxicum中含有的脂生物碱。 | |||
T83232 |
8-Methoxymarmesin
|
||
8-Methoxymarmesin为可从Brosimum gaudichaudii中提取的天然化合物。 | |||
T82220 |
Hedysarimcoumestan B
|
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Hedysarimcoumestan B为从Hedysarum multijugum根部提取的天然化合物。 | |||
T131453 |
Yunaconitine (Vilmorrianine B and other names)
|
Others | Others |
Yunaconitine (Vilmorrianine B and other names) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131453。 | |||
TN5880 |
Mesuol
|
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Mesuol has antioxidant activity, it shows very high scavenging activity against DPPH radical; it also has immunomodulatory activity, can potentiate percentage neutrophil adhesion in neutrophil adhesion test in rats and phagocytosis in carbon clearance assay. Mesuol can suppress HIV-1 replication in Jurkat T cells, it inhibits TNFα-induced HIV-1-LTR transcriptional activity by targeting the nuclear factor-κB (NF-κB) pathway. | |||
T19772 |
Mesembrenone
(+)-Mesembrenone |
Others | Others |
Mesembrenone is a selective the serotonin transporter (SERT) inhibitor. Mesembrenone is the main alkaloid of Sceletium tortuosum. | |||
TN2673 |
5-Methoxy-2',3'-dehydromarmesin
2-(1-Hydroxy-1-methylethyl)-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one |
Others | Others |
5-Methoxy-2',3'-dehydromarmesin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2673,CAS号为 54087-32-0。 | |||
T83445 |
16-Epipyromesaconitine
|
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16-Epipyromesaconitine为通过Mesaconitine热解产生的天然产物。 | |||
T124967 |
D7-Mesembrenone
|
Others | Others |
D7-Mesembrenone 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124967,CAS号为 35714-44-4。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00132 |
Mesothelin Protein, Human, Recombinant
MPF,SMRP,Mesothelin |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3. | |||
TMPY-06787 |
Mesothelin Protein, Mouse, Recombinant (His)
MPF,mesothelin |
Mouse | HEK293 Cells |
Mesothelin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is Q61468-1. | |||
TMPY-06773 |
Mesothelin Protein, Human, Recombinant (His & Avi), Biotinylated
Mesothelin,SMRP,MPF |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 35.44 kDa and the accession number is AAH09272.1. | |||
TMPK-00961 |
MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), FITC-Labeled
MSLN,MPF,CAK1,Mesothelin,MPFSMRP,SMR |
Human | HEK293 Cells |
MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.2 kDa and the accession number is Q13421-2. | |||
TMPK-01368 |
MSLN/Mesothelin Protein, Cynomolgus, Recombinant (hFc)
CAK1,Mesothelin,SMR,MSLN,MPFSMRP,MPF,CAK1 antigen |
Cynomolgus | HEK293 Cells |
MSLN/Mesothelin Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 58.6 kDa and the accession number is A0A2K5TW94-1. | |||
TMPJ-00443 |
PCSK9 Protein, Macaca nemestrina, Recombinant (His)
Proprotein Convertase Subtilisin/Kexin Type 9,PCSK9,PC9,Prop... |
Macaca nemestrina | HEK293 Cells |
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development. | |||
TMPH-02458 |
PRNP Protein, Mesocricetus auratus, Recombinant (His & Myc)
PrP33-35C,PrP27-30,Major prion protein,PRNP |
Mesocricetus auratus | E. coli |
PRNP Protein, Mesocricetus auratus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.3 kDa and the accession number is P04273. | |||
TMPH-02448 |
Mal d 1 Protein, Malus domestica, Recombinant (His)
Allergen Mal d I,MALD1,Major allergen Mal d 1 |
Apple | P. pastoris (Yeast) |
Mal d 1 Protein, Malus domestica, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.5 kDa and the accession number is P43211. | |||
TMPY-06737 |
Equ c 1 Protein, Domestic horse, Recombinant
|
Domestic horse | E. coli |
Equ c 1 Protein, Domestic horse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.1 kDa. | |||
TMPY-05129 |
Mesothelin Protein, Human, Recombinant (His), Biotinylated
SMRP,Mesothelin,MPF |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q13421-2. | |||
TMPK-01377 |
MSLN/Mesothelin Protein, Cynomolgus, Recombinant (His)
CAK1,CAK1 antigen,MSLN,Mesothelin,MPF,SMR,MPFSMRP |
Cynomolgus | HEK293 Cells |
MSLN/Mesothelin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 33 kDa and the accession number is A0A2K5TW94-1. | |||
TMPK-01397 |
MSLN/Mesothelin Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
MPFSMRP,Mesothelin,MPF,SMR,MSLN,CAK1 |
Cynomolgus | HEK293 Cells |
MSLN/Mesothelin Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 33 kDa and the accession number is A0A2K5TW94-1. | |||
TMPH-02457 |
IL-4 Protein, Mesocricetus auratus, Recombinant (His)
Lymphocyte stimulatory factor 1,B-cell stimulatory factor 1,... |
Mesocricetus auratus | P. pastoris (Yeast) |
IL-4 Protein, Mesocricetus auratus, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is Q60440. | |||
TMPH-02456 |
IL-12B Protein, Mesocricetus auratus, Recombinant (His & Myc)
Cytotoxic lymphocyte maturation factor 40 kDa subunit,IL12B,... |
Mesocricetus auratus | E. coli |
IL-12B Protein, Mesocricetus auratus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.8 kDa and the accession number is Q8CJE6. | |||
TMPH-02459 |
INGAP Protein, Mesocricetus auratus, Recombinant (His)
INGAP,Pancreatic beta cell growth factor,Islet neogenesis-as... |
Mesocricetus auratus | E. coli |
Constituent of ilotropin, which is a partially purified preparation of cellophane wrapping (CW) pancreata. Capable of initiating duct cell proliferation, a prerequisite for islet neogenesis. INGAP Protein, Mesocricetus auratus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.8 kDa and the accession number is Q92778. | |||
TMPY-02875 |
Mesothelin Protein, Human, Recombinant (hFc), Biotinylated
MPF,SMRP,mesothelin |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.7 kDa and the accession number is Q13421-2. | |||
TMPY-06914 |
Mesothelin Protein, Rat, Recombinant (His)
mesothelin |
Rat | HEK293 Cells |
Mesothelin Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.48 kDa and the accession number is Q9ERA7. | |||
TMPY-03146 |
Mesothelin Protein, Human, Recombinant (His)
MPF,Mesothelin,SMRP |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q13421-2. | |||
TMPH-02450 |
MALD3 Protein, Malus domestica, Recombinant (His & SUMO)
Non-specific lipid-transfer protein,MALD3 |
Apple | E. coli |
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. MALD3 Protein, Malus domestica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 25.1 kDa and the accession number is Q9M5X7. | |||
TMPY-06861 |
Mesothelin Protein, Mouse, Recombinant (His & Avi)
MPF,mesothelin |
Mouse | HEK293 Cells |
Mesothelin Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 37.41 kDa and the accession number is Q61468-1. | |||
TMPY-06689 |
Fel d 1 Protein, Felis domesticus, Recombinant
|
Felis domesticus | E. coli |
Fel d 1 Protein, Felis domesticus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.6 kDa. | |||
TMPY-06904 |
Mesothelin Protein, Cynomolgus, Recombinant (His)
mesothelin |
Cynomolgus | HEK293 Cells |
Mesothelin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.31 kDa and the accession number is XM_005590816.3. | |||
TMPY-02951 |
Mesothelin Protein, Human, Recombinant (hFc)
Mesothelin,MPF,SMRP |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.7 kDa and the accession number is Q13421-2. | |||
TMPY-06674 |
Fel d 4 Protein, Felis domesticus, Recombinant
|
Felis domesticus | E. coli |
Fel d 4 Protein, Felis domesticus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 32.5 kDa. | |||
TMPK-01026 |
MSLN/Mesothelin Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
MPFSMRP,SMR,MSLN,CAK1,Mesothelin,MPF |
Mouse | HEK293 Cells |
MSLN/Mesothelin Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 35.2 kDa and the accession number is Q61468-1. | |||
TMPK-00962 |
MSLN/Mesothelin Protein, Human, Recombinant (His & Avi)
MPFSMRP,MSLN,MPF,SMR,CAK1,Mesothelin |
Human | HEK293 Cells |
MSLN/Mesothelin Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.2 kDa and the accession number is Q13421-2. | |||
TMPK-00963 |
MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), Biotinylated
SMR,MSLN,CAK1,MPF,Mesothelin,MPFSMRP |
Human | HEK293 Cells |
MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.2 kDa and the accession number is Q13421-2. | |||
TMPK-00959 |
MSLN/Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated
Mesothelin,MPFSMRP,MPF,CAK1,MSLN,SMR |
Human | HEK293 Cells |
MSLN/Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 61.1 kDa and the accession number is Q13421-2. | |||
TMPH-02449 |
Mal d 1 Protein, Malus domestica, Recombinant (His & SUMO)
MALD1,Major allergen Mal d 1,Allergen Mal d I |
Apple | E. coli |
Mal d 1 Protein, Malus domestica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 33.5 kDa and the accession number is P43211. | |||
TMPY-01451 |
MESDC2 Protein, Human, Recombinant (His)
MESD,mesoderm development candidate 2,BOCA |
Human | HEK293 Cells |
MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity reside... | |||
TMPY-06736 |
Bos d 2 Protein, Bos domesticus, Recombinant
|
Bos domesticus | E. coli |
Bos d 2 Protein, Bos domesticus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 32.4 kDa. | |||
TMPY-03116 |
Mesothelin Protein, Human, Recombinant (aa 296-580, hFc)
MPF,SMRP,Mesothelin |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant (aa 296-580, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.7 kDa and the accession number is Q13421-2. | |||
TMPY-06776 |
Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated
MPF,SMRP,Mesothelin |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 60.72 kDa and the accession number is AAH09272.1. | |||
TMPK-00960 |
MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), PE-Labeled
MSLN,CAK1,MPF,Mesothelin,SMR,MPFSMRP |
Human | HEK293 Cells |
MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), PE-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.2 kDa and the accession number is Q13421-2. | |||
TMPH-02814 |
Nmes1 Protein, Mouse, Recombinant (His & SUMO)
Normal mucosa of esophagus-specific gene 1 protein,Nmes<... |
Mouse | E. coli |
Nmes1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12300 |
Olmesartan-d4
RNH-6270 D4,奥美沙坦 D4 |
Others | Others |
Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure. | |||
TMIJ-0222 |
Exemestane-d3
|
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Exemestane-d3 是 Exemestane 的氘代化合物。Exemestane 的 CAS 号为 107868-30-4。Exemestane 是一种选择性的、具有口服活性的、不可逆的甾体芳香酶抑制剂,能够作用于人胎盘芳香酶 (IC50:30 nM) 和大鼠卵巢芳香酶 (IC50:40 nM),可用于研究激素依赖性乳腺癌。 | |||
TMIJ-0223 |
Exemestane-13C-d3
|
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Exemestane-13C-d3 是 Exemestane 的 13C 和氘代化合物。Exemestane 的 CAS 号为 107868-30-4。Exemestane 是一种选择性的、具有口服活性的、不可逆的甾体芳香酶抑制剂,能够作用于人胎盘芳香酶 (IC50:30 nM) 和大鼠卵巢芳香酶 (IC50:40 nM),可用于研究激素依赖性乳腺癌。 | |||
TMID-0077 |
Reboxetine-d5 Mesylate
|
||
Reboxetine-d5 Mesylate 是 Reboxetine Mesylate 的氘代化合物。Reboxetine Mesylate 的 CAS 号为 98769-84-7。Reboxetine mesylate 是一种高效、选择性的,特异性的去甲肾上腺素再摄取抑制剂 (NARI),能够抑制去甲肾上腺素再摄取(Ki=8 nM),可用于抑郁症的研究。 | |||
T36903 |
Rasagiline-13C3 (mesylate)
Rasagiline-13C3 (mesylate) |
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Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede... | |||
T12227 |
Nimesulide D5
|
COX | Immunology/Inflammation; Neuroscience |
Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective inhibitor OF COX-2(IC50s of 70 nM-70 μM) | |||
TMID-0230 |
Hexestrol-d6 (hexane-2,2,3,4,5,5-d6) (meso)
|
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Hexestrol-d6 (hexane-2,2,3,4,5,5-d6) (meso) 是 Hexestrol 的氘代化合物。Hexestrol 的 CAS 号为 84-16-2。Hexestrol 是非甾体合成雌激素,对雌激素受体ERα和ERβ的Ki=均为 0.06 nM。它可增加牛的体重,也可用于雌激素缺乏引起的疾病的研究。 | |||
TMID-0241 |
Olmesartan-d6 Acid
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Olmesartan-d6 Acid 是 Olmesartan Acid 的氘代化合物。Olmesartan Acid 的 CAS 号为 144689-24-7。Olmesartan 是一种血管紧张素II受体 (AT1R) 拮抗剂,常用于研究高血压。 | |||
TMID-0291 |
Prochlorperazine-d3 Dimesylate
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Prochlorperazine-d3 Dimesylate 是 Prochlorperazine Dimesylate 的氘代化合物。Prochlorperazine Dimesylate 的 CAS 号为 51888-09-6。 | |||
T12693 |
Rasagiline 13C3 mesylate racemic
TVP1012 13C3 racemic,AGN1135 13C3 racemic |
Others | Others |
Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor. | |||
TMIH-0244 |
Fomesafen-d3
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Fomesafen-d3 是 Fomesafen 的氘代化合物。Fomesafen 的 CAS 号为 72178-02-0。Fomesafen 是原卟啉原 IX 氧化酶的选择性抑制剂。Fomesafen用作除草剂,具有低毒性和高选择性的优点。 | |||
TMIH-0330 |
Mesotrione-d3
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Mesotrione-d3 是 Mesotrione 的氘代化合物。Mesotrione 的 CAS 号为 104206-82-8。Mesotrione 是一种苯甲酰环己二酮类除草剂,是一种竞争性羟基苯基丙酮酸双加氧酶酶抑制剂。它对玉米作物具有选择性,它在易感作物中代谢速度快,耐受性较高。 | |||
TMIJ-0229 |
Mesalamine-d3
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Mesalamine-d3 是 Mesalamine 的氘代化合物。Mesalamine 的 CAS 号为 89-57-6。5-Aminosalicylic Acid 是一种特异性的PPARγ激动剂,还抑制 p21-激活激酶1 (PAK1) 和NF-κB,具有抗炎活性。 | |||
T68918 |
Phenytoin-d10
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Phenytoin-d10 is intended for use as an internal standard for the quantification of phenytoin by GC- or LC-MS. Phenytoin is an anticonvulsant agent and active metabolite of fosphenytoin. Phenytoin is formed from fosphenytoin by tissue phosphatases. It inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner. Phenytoin reduces the neuronal firing frequency and decreases the amplitude of excitatory post-synaptic potentials (EPSPs) in electrically stimulated rat corticostriatal... | |||
T37847 |
Zonisamide-13C2,15N
Zonisamide-13C2,15N |
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Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium... |