5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.

Cat. No.	Product Name	CAS No.	Purity
T0039	Dapoxetine 达波西汀	119356-77-3	98%
T0039	Dapoxetine 是一种选择性5-羟色胺再摄取抑制剂，用于治疗早泄。
T3086	Mesoridazine Besylate 苯磺酸美索达嗪	32672-69-8	98%
T3086	Mesoridazine Besylate 是一种哌啶类精神安定药，属于称为吩噻嗪类的药物，用于治疗精神分裂症。它是硫利达嗪的代谢物。
T62269	F 14679 化合物F 14679	208109-38-0	98%
T62269	F 14679 是一种有效的5-HT1A 激动剂（pKi=10.23），具有 Ca2t 的最大反应与5-HT 相似。
T28414	Piclozotan 化合物Piclozotan	182415-09-4	98%
T28414	Piclozotan (anhydrous) 是一种 5-HT1A 受体激动剂，在短暂的大脑中动脉闭塞（t-MCAO）模型中表现出显着的神经保护活性,可以改善晚期帕金森病患者的运动并发症。
T4348	Syk Inhibitor II 化合物Syk Inhibitor II	726695-51-8	98%
T4348	Syk Inhibitor II 是一种可渗透细胞、具有 ATP 竞争性的嘧啶-甲酰胺化合物，可选择性且可逆地抑制 Syk，IC50为 41 nM。
T8702	SKF-83566 化合物SKF-83566	99295-33-7	98%
T8702	SKF-83566 是一种具有血脑渗透性和口服活性的 D1 样多巴胺受体拮抗剂和一种较弱的竞争性 5-HT2 受体拮抗剂，Ki 为 11 nM。它是竞争性多巴胺转运蛋白抑制剂，可用于研究帕金森氏症和对尼古丁渴望的缓解的相关研究。
T1769	Pardoprunox 帕多芦诺	269718-84-5	98%
T1769	Pardoprunox 是多巴胺受体D2、D3部分激动剂和5-HT1A 激动剂，pEC50分别为 8、9.2 和 6.3。
TN1415	Auraptenol 化合物Auraptenol	1221-43-8	98%
TN1415	Auraptenol possesses robust antidepressant-like efficacy in mice.
T15100	Desmethyl cariprazine 化合物 T15100	839712-15-1	98%
T15100	Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (K...
T17095	TIK-301 化合物 T17095	118702-11-7	98%
T17095	TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM,...
T11949	Masupirdine mesylate 化合物 T11949	1791396-46-7	98%
T11949	Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's d...
T19381	Isobutyryl-L-carnitine 化合物 T19381	25518-49-4	98%
T19381	Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.
T13339	Wf-516 化合物 T13339	310392-94-0	98%
T13339	Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant activit...
TN4713	Onitisin 化合物 TN4713	53823-03-3	98%
TN4713	Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
T10380	AS19 化合物 T10380	1000578-26-6	98%
T10380	AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM). AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Ki...
T15026	Cyamemazine 化合物 T15026	3546-03-0	98%
T15026	Cyamemazine, contains the phenothiazine chromophore, is a neuroleptic agent used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki: 12 nM), 5-HT2A (Ki: 1.5 nM)...
T13021	Sulamserod 化合物 T13021	219757-90-1	98%
T13021	Sulamserod is an antagonist of 5-HT4 receptor, has antiarrhythmic activities.
T16433	Pancopride 化合物 T16433	121650-80-4	98%
T16433	Pancopride is a new effective and selective antagonist of the 5-HT3 receptor.
T12262L	NPS ALX Compound 4a dihydrochloride 化合物 T12262L	1781934-44-8	98%
T12262L	NPS ALX Compound 4a dihydrochloride is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
T10114	3-Hydroxy agomelatine 化合物 T10114	166526-99-4	98%
T10114	3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).