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Search Results for " p53 "

Targets Recommended: p53 Mdm2 p53

289

抑制剂 & 化合物

38

天然产物

3

化合物库

3

TargetMol 试剂盒

66

重组蛋白

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Cat. No.	Product Name
L8700	铁死亡化合物库		779 compounds
	779 种与铁死亡通路相关的化合物，可用于高通量和高内涵筛选；
L2194	抗结直肠癌化合物库		1545 compounds
	1545 种与结直肠癌相关的化合物，可以用于高通量和高内涵筛选；
L2130	抗癌细胞代谢库		1268 compounds
	1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；

化合物库

铁死亡化合物库

Cat.No: L8700

Compounds: 779

抗结直肠癌化合物库

Cat.No: L2194

Compounds: 1545

抗癌细胞代谢库

Cat.No: L2130

Compounds: 1268

Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0134	p53 inhibitor/reactivator kit p53 inhibitor/reactivator kit
CL0085	HSP inhibitor kit HSP inhibitor kit
CL0145	Casein Kinase inhibitor kit Casein Kinase inhibitor kit

TargetMol 试剂盒

p53 inhibitor/reactivator kit

Cat.No: CL0134

HSP inhibitor kit

Cat.No: CL0085

Casein Kinase inhibitor kit

Cat.No: CL0145

Cat. No.	Product Name	Target	Signaling Pathways
T72026	p53-MDM2-IN-1	Mdm2; p53	Apoptosis
	p53-MDM2-IN-1 (Example 30) 是一种 p53-MDM2/X 蛋白相互作用的抑制剂，Ki 值为 23.35 µM。p53-MDM2-IN-1 能用于抗肿瘤研究。
T67698	p53-Mdm2 inhibitor 4	Mdm2; p53	Apoptosis
	p53-Mdm2 inhibitor 4 抑制 p53-MDM2 蛋白质-蛋白质相互作用。
T80233	p53 CBS p53 Consensus binding sequence
	p53 CBS（p53共有DNA结合位点）是一种具备生物活性的肽类化合物。
T72771	p53 Activator 7	Apoptosis	Apoptosis
	p53 Activator 7 是一种高效性和细胞渗透性的 p53 突变 Y220C (MDM-2/p53) 激活剂，可诱导细胞凋亡。
T24440	MDM2-p53-IN-1b MDM2-p53 inhibitor 1b,MDM2 p53 IN 1b
	MDM2-p53-IN-1b is the MDM2-p53 interaction inhibitor.
TP1794	p53 (17-26) p53 17-26
	This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2.
T67858	STIMA-1 2-Vinylquinazolin-4-ol,p53 Activator VII	Others	Others
	STIMA-1 (2-Vinylquinazolin-4-ol) 是一种活性化合物，可以恢复 p63 的活性。STIMA-1 可以刺激角质形成细胞的增殖和分化。
T12351	p53 and MDM2 proteins-interaction-inhibitor (racemic) p53-and-mdm2-proteins-interaction-inhibitor-racemic	Others	Others
	p53 and MDM2 proteins-interaction-inhibitor (racemic) is an inhibitor of the interaction between p53 and MDM2 proteins.
TP2281	p53 tumor suppressor fragment	Others	Others
	p53 tumor suppressor fragment (232-240) is a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where i
T22980	MIRA-1 p53 Activator VIII,1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione,(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate,NSC 19630,WRN Helicase Inhibitor	DNA/RNA Synthesis; p53	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	MIRA-1 (WRN Helicase Inhibitor) 是马来酰亚胺类似物。它可以恢复p53依赖的转录转激活诱导 p53 突变细胞凋亡，具有抗肿瘤作用。
T12350	p53 and MDM2 proteins-interaction-inhibitor dihydrochloride	Others	Others
	p53 and MDM2 proteins-interaction-inhibitor dihydrochloride is a interaction inhibitor between p53 and MDM2 proteins.
T34830	Tetrofosmin P 53,P53
	Tetrofosmin is a phosphine developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.
T61369	p53 Activator 2
	p53 Activator 2 (compound 10ah) 插入DNA，导致显著的DNA双链断裂。该化合物通过增加p53、p-p53、CDK4、p21的表达，使细胞周期在G2/M期停滞，诱导细胞凋亡，并显著降低抗凋亡蛋白Bcl-2、Bcl-xL和cyclin B1的水平。此外，p53 Activator 2表现出对MGC-803细胞的抗增殖效果，其IC50为1.73 μM，且在MGC-803异种移植肿瘤模型中展示出有效的抗癌活性。
T72770	p53 Activator 5
	p53 Activator 5 是一种有效的 p53激活剂，SC150 值 <0.05 mM。p53 Activator 5 可以结合突变体 p53 并恢复 p53 突变体结合 DNA 的能力。p53 Activator 5 具有抗肿瘤活性。
T72769	p53 Activator 3
	p53 Activator 3，一种有效的p53激活剂，其SC150值<0.05 mM。该化合物能结合p53突变体并恢复其与DNA结合的功能，显示出抗肿瘤活性。
T21578	NSC 66811	Mdm2	Apoptosis
	NSC 66811 是一种MDM2-p53抑制剂，其结合到 MDM2 的Ki 值为 120 nM。
T64079	Mutant p53 modulator-1
	Mutant p53 modulator-1 是一种突变型 p53 调节剂。Mutant p53 modulator-1 能够阻碍含有 p53 突变的癌症的进展。
T7057	Methylstat	Histone Demethylase; Others	Chromatin/Epigenetic; Others
	Methylstat 是一种含有 Jumonji C 结构域的组蛋白去甲基化酶 (JMJD) 抑制剂的甲酯前药，具有良好的细胞渗透性。在体外试验中，methylstat 的游离酸可抑制 JMJD2A、JMJD2C、JMJD2E、PHF8 和 JMJD3，IC50 值分别约为 4.3、3.4、5.9、10 和 43 µM。 Methylstat 抑制 JMJD2C 敏感的食管癌细胞系 KYSE150 的生长，GI50 为 5.1 µM，而 methylstat 的游离酸在高达 100 µM 时不抑制细胞生长。 Methylstat 以浓度依赖性方式在多个位点诱导组蛋白高甲基化（KYSE150 细胞中 H3K4me3 和 H3K9me3 的 EC50 = 10.3 和 8.6 µM，MCF-7 细胞中的 EC50 分别为 6.7 和 6.3 µM）。
T27029	cjoc42 cjoc 42,cjoc-42
	Cjoc42 是gankyrin 的抑制剂，以剂量依赖性方式抑制 gankyrin 活性。它可防止 p53 蛋白水平的降低。它恢复 p53 依赖性转录和对 DNA 损伤的敏感性。
T6610	XI-006 NSC 207895,可可碱	Mdm2; p53	Apoptosis
	XI-006 (XI-006) 是一种DNA 破坏剂、抗肿瘤剂和p53的激活剂。
T9698	UC2288	Mdm2; p53	Apoptosis
	UC2288 是新型的、细胞通透性、口服有效的p21衰减试剂，基于索拉非尼的结构合成。在不依赖于p53的情况下，它可以下调 p21 mRNA 的表达，降低 p21 蛋白水平，对 p21 蛋白的稳定性影响很小。它对VEGFR2 和 Raf 激酶没有抑制作用，即使在 10 μM。
T63373	S100A2-p53-IN-1
	S100A2-p53-IN-1（化合物 51）是一款针对S100A2-p53相互作用的抑制剂，专用于阻断S100A2与p53的相互作用。作为一种与Ca2+结合并参与细胞信号传递的蛋白，S100A2在胰腺癌中表达上调。S100A2-p53-IN-1特别针对MiaPaCa-2胰腺癌细胞系，显示出良好的生长抑制效果（GI50为1.2-3.4 μM）。
T12257	NSC 146109 hydrochloride	Apoptosis; Others	Apoptosis; Others
	NSC 146109 hydrochloride 是一种靶向 MDMX 的 p53 激活剂。 NSC 146109 hydrochloride 可用于乳腺癌研究。
T1887	Inauhzin INZ	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Inauhzin (INZ) 是一种新型小分子，通过抑制 SIRT1 活性有效地重新激活 p53，促进人 Y 细胞的 p53 依赖性凋亡，在 A549 细胞中的IC50为3 uM。
T9122	XL177A	DUB	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
	XL177A 是一种选择性不可逆的 USP7 抑制剂，IC50为 0.34 nM。它通过 p53 依赖性机制引发癌杀伤细胞作用。
T2464	ZMC1	p53	Apoptosis
	NSC-319726 (ZMC1)是一种突变型 p53R175 再激活剂，可抑制表达 p53R175 突变的成纤维细胞的生长，IC50值为8nM。
TP2299	tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]	Others	Others
	Tumor protein p53 binding protein (53BP1) has been identified in a yeast two-hybrid screen as a protein that interacts with the central DNA–binding domain of p532. Similar to breast cancer susceptibility gene 13, 4 (BRCA1; 53BP1 enhances p53-dependent tra
T74936	MDM2/4-p53-IN-3
	MDM2/4-p53-IN-3，一种针对MDM2/4-p53蛋白-蛋白相互作用(PPI)的抑制剂，IC50s分别为18.5 nM（MDM2-p53）与14.8 nM（MDM4-p53）。该化合物主要应用于癌症研究领域，特别是结肠癌的研究。
T74935	MDM2/4-p53-IN-2
	MDM2/4-p53-IN-2 (2q) 是一种有效的双重 MDM2/ MDM4抑制剂和 p53激活剂，作用于 MDM2-p53 和 MDM4-p53 复合物的 IC50值分别是 70.7 nM 和 81.4 nM。MDM2/4-p53-IN-2 可以调控细胞周期，诱导细胞凋亡(apoptosis)，具有抗癌活性。
T1873	Tenovin-3 Tenovin3	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Tenovin-3 是一种 p53激活剂。
T72832	MDM2-p53-IN-16
	MDM2-p53-IN-16 是MDM2-p53复合体抑制剂，其IC50值针对人MDM2-p532复合体为4.3 nM。该化合物能够重新激活p53，进而诱导多形性成胶质细胞瘤（GBM）细胞的凋亡和细胞周期阻滞，适用于癌症研究。
T72877	p53-HDM2-IN-1
	p53-HDM2-IN-1 是一种有效的 p53-HDM2蛋白-蛋白相互作用抑制剂，IC50值为 0.103 μM。p53-HDM2-IN-1 可用于癌症研究。
T16523L	PhiKan 083	Mdm2	Apoptosis
	PhiKan 083 是咔唑衍生物，可以稳定p53的突变体Y220C，Kd 值为 167 μM。它可用于癌症研究。
T8774	MS7972	Epigenetic Reader Domain	Chromatin/Epigenetic
	MS7972 是一种小分子，能阻断人 p53 和 CREB 结合。它在50 μM 的时候几乎可以完全阻断 BRD 的相互作用。
T6910	NSC59984	p53	Apoptosis
	NSC59984 是 p53 通路激活剂，可诱导突变 p53 蛋白降解和 p73 活化。它通过 MDM2 和泛素-蛋白酶体途径而诱导突变型 p53 蛋白降解。
T24730	Roslin 2 bromide Roslin-2,Benzylhexamethylenetetramine bromide,Roslin2	FAK; p53	Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Roslin 2 bromide (Benzylhexamethylenetetramine bromide) 是一种 p53 再激活剂，可破坏 FAK 和 p53 的结合。 Roslin 2 bromide 具有抗癌作用。
T16350	NSC-87877	Apoptosis; Phosphatase	Apoptosis; Metabolism
	NSC-87877 是一种Shp2和Shp1蛋白质酪氨酸磷酸酶抑制剂，IC50值分别为0.318 μM 和0.355 μM。它还抑制双特异性磷酸酶26。
T7703	PK11007	Reactive Oxygen Species; p53	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	PK11007 是一种温和的硫醇烷基化剂，具有抗癌活性。它通过两个表面暴露的半胱氨酸的选择性烷基化来稳定 p53。它通过增加活性氧水平诱导突变的 p53癌细胞死亡。
T63438	rel-MDM2/4-p53-IN-3
	rel-MDM2/4-p53-IN-3 是 MDM2/4-p53 蛋白质-蛋白质相互作用 (PPI) 抑制剂，能够作用于MDM2-p53、MDM4-p53，其IC50值分别为18.5 nM、14.8 nM。rel-MDM2/4-p53-IN-3 能够用于研究癌症，如结肠癌。
T3289	Amifostine 氨磷汀,Ethyol,WR2721,Gammaphos	Others; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Others
	Amifostine (Ethyol) 是一种广谱细胞保护剂和辐射防护剂，具有清除自由基的作用。它可选择性保护正常组织免受放射线和化学疗法造成的损害。它是有效的 HIF-α1和 p53诱导剂，可降低肾脏毒性并具有抗血管生成作用。
T8554	KCC-07	DNA Alkylator/Crosslinker	DNA Damage/DNA Repair
	KCC-07 是一种甲基-CpG 结合域蛋白 2 (MBD2) 的选择性、强效和脑渗透抑制剂，具有抗癌活性。它阻止 MBD2 与甲基化 DNA 结合并激活脑特异性血管生成抑制剂 1，诱导抗增殖 BAI1/p53/p21 信号传导。
T39233	SIRT7 inhibitor 97491	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	SIRT7 inhibitor 97491 是SIRT7的有效抑制剂，IC50为 325 nM。SIRT7 inhibitor 97491以剂量依赖性的方式降低 SIRT7 去乙酰化酶活性。它通过在 K373/382 处进行乙酰化来提高 p53 的稳定性，从而防止肿瘤进展。它通过 caspase 途径促进凋亡。
T63748	rel-MDM2/4-p53-IN-2
	rel-MDM2/4-p53-IN-2 (2q) 是有效的双重 MDM2/MDM4 抑制剂和 p53 激活剂，能够作用于 MDM2-p53 复合物 (IC50: 70.7 nM) 和 MDM4-p53 复合物 (IC50: 81.4 nM)。rel-MDM2/4-p53-IN-2 能够调控细胞周期，诱导细胞凋亡(apoptosis)，表现出抗癌效果。
T21773	SP-141 SP 141	Mdm2	Apoptosis
	SP-141 是一种 MDM2 抑制剂，可促进 MDM2 自身泛素化和降解，具有抗癌活性。
T12472	Pifithrin-α, p-Nitro, Cyclic PFN-α	p53	Apoptosis
	Pifithrin-α, p-Nitro, Cyclic (PFN-α) 是 p53 的细胞渗透性和活性形式抑制剂。它对暴露于 Etoposide 的皮层神经元的保护作用比 Pifithrin-α 强一个数量级，ED50为30 nM。它也作为 p53 转录后的活性抑制剂。
T17204	UNC0321	Histone Methyltransferase	Chromatin/Epigenetic
	UNC0321 是一种有效的组蛋白甲基转移酶 G9a 抑制剂，在 ECSD 和 CLOT 测定中，Ki 为 63 pM，IC50 分别为 9 nM 和 6 nM。 UNC0321 抑制 GLP，在 ECSD 和 CLOT 试验中 IC50 分别为 15 nM 和 23 nM。
T4459	PK11000	DNA Alkylator/Crosslinker	DNA Damage/DNA Repair
	PK11000 是一种烷化剂，可通过共价半胱氨酸修饰来稳定野生型和突变型p53的 DNA 结合结构域。
T6911	NSC-87877 disodium NSC87877	Apoptosis; Phosphatase	Apoptosis; Metabolism
	NSC-87877 disodium (NSC87877) 是一种有效的Shp2和Shp1蛋白质酪氨酸磷酸酶抑制剂，IC50值分别为0.318 μM 和0.355 μM。NSC-87877还抑制双特异性磷酸酶26。
T17203	UNC0224	Histone Methyltransferase	Chromatin/Epigenetic
	UNC0224 是 G9a 的特异性抑制剂，Ki 为 2.6 nM，IC50 为 15 nM。 UNC0224 还有效抑制 GLP，IC50 值为 20-58 nM。
T6879	LLY-507 LLY507,LLY 507	Histone Methyltransferase	Chromatin/Epigenetic
	LLY-507 是一种有效的、细胞活性的、特异性的蛋白质赖氨酸甲基转移酶 SMYD2 抑制剂。它是一种化学探针，用于解析 SMYD2 在癌症和其他生物过程中的功能。它有抑制 SMYD2 甲基化 p53 肽的能力，IC50小于 15 nM。

化合物

p53-MDM2-IN-1

Cat.No: T72026

Target: Mdm2, p53

p53-Mdm2 inhibitor 4

Cat.No: T67698

Target: Mdm2, p53

Cat.No: T80233

Synonym: p53 Consensus binding sequence

p53 Activator 7

Cat.No: T72771

Target: Apoptosis

MDM2-p53-IN-1b

Cat.No: T24440

Synonym: MDM2-p53 inhibitor 1b,MDM2 p53 IN 1b

Cat.No: TP1794

Synonym: p53 17-26

Cat.No: T67858

Synonym: 2-Vinylquinazolin-4-ol,p53 Activator VII

Target: Others

p53 and MDM2 proteins-interaction-inhibitor (racemic)

Cat.No: T12351

Synonym: p53-and-mdm2-proteins-interaction-inhibitor-racemic

Target: Others

p53 tumor suppressor fragment

Cat.No: TP2281

Target: Others

Cat.No: T22980

Synonym: p53 Activator VIII,1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione,(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate,NSC 19630,WRN Helicase Inhibitor

Target: DNA/RNA Synthesis, p53

p53 and MDM2 proteins-interaction-inhibitor dihydrochloride

Cat.No: T12350

Target: Others

Cat.No: T34830

Synonym: P 53,P53

p53 Activator 2

Cat.No: T61369

p53 Activator 5

Cat.No: T72770

p53 Activator 3

Cat.No: T72769

Cat.No: T21578

Target: Mdm2

Mutant p53 modulator-1

Cat.No: T64079

Cat.No: T7057

Target: Histone Demethylase, Others

Cat.No: T27029

Synonym: cjoc 42,cjoc-42

Cat.No: T6610

Synonym: NSC 207895,可可碱

Target: Mdm2, p53

Cat.No: T9698

Target: Mdm2, p53

S100A2-p53-IN-1

Cat.No: T63373

NSC 146109 hydrochloride

Cat.No: T12257

Target: Apoptosis, Others

Cat.No: T1887

Synonym: INZ

Target: Sirtuin

Cat.No: T9122

Target: DUB

Cat.No: T2464

Target: p53

tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]

Cat.No: TP2299

Target: Others

MDM2/4-p53-IN-3

Cat.No: T74936

MDM2/4-p53-IN-2

Cat.No: T74935

Cat.No: T1873

Synonym: Tenovin3

Target: Sirtuin

MDM2-p53-IN-16

Cat.No: T72832

p53-HDM2-IN-1

Cat.No: T72877

Cat.No: T16523L

Target: Mdm2

Cat.No: T8774

Target: Epigenetic Reader Domain

Cat.No: T6910

Target: p53

Roslin 2 bromide

Cat.No: T24730

Synonym: Roslin-2,Benzylhexamethylenetetramine bromide,Roslin2

Target: FAK, p53

Cat.No: T16350

Target: Apoptosis, Phosphatase

Cat.No: T7703

Target: Reactive Oxygen Species, p53

rel-MDM2/4-p53-IN-3

Cat.No: T63438

Cat.No: T3289

Synonym: 氨磷汀,Ethyol,WR2721,Gammaphos

Target: Others, HIF/HIF Prolyl-Hydroxylase

Cat.No: T8554

Target: DNA Alkylator/Crosslinker

SIRT7 inhibitor 97491

Cat.No: T39233

Target: Sirtuin

rel-MDM2/4-p53-IN-2

Cat.No: T63748

Cat.No: T21773

Synonym: SP 141

Target: Mdm2

Pifithrin-α, p-Nitro, Cyclic

Cat.No: T12472

Synonym: PFN-α

Target: p53

Cat.No: T17204

Target: Histone Methyltransferase

Cat.No: T4459

Target: DNA Alkylator/Crosslinker

NSC-87877 disodium

Cat.No: T6911

Synonym: NSC87877

Target: Apoptosis, Phosphatase

Cat.No: T17203

Target: Histone Methyltransferase

Cat.No: T6879

Synonym: LLY507,LLY 507

Target: Histone Methyltransferase

Cat. No.	Product Name	Target	Signaling Pathways
T8678	Naphthazarin 萘茜,5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) 是来自毛紫草的一种天然产物，通过氧化应激、线粒体凋亡诱导因子的激活、微管的解聚、干扰溶酶体功能和 p53 依赖性 p21 激活，可触发细胞凋亡并具有抗肿瘤作用。
T5061	Lumichrome 7,8-Dimethylalloxazine,光色素	Others	Others
	Lumichrome (7,8-Dimethylalloxazine) 是人类体内的内源性化合物，由核黄素光降解产生。它利用 p53 依赖机制抑制人肺癌细胞生长并诱导凋亡。
T0132	Etoposide VP-16,依托泊苷,依托泊甙,VP-16-213	Apoptosis; Mitophagy; Topoisomerase; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; DNA Damage/DNA Repair; Microbiology/Virology
	Etoposide (VP-16-213) 是一种拓扑异构酶 II 的抑制剂，通过与拓扑异构酶 II 和 DNA 形成复合物来抑制 DNA 合成 (IC50=60.3 μM)。Etoposide 具有抗肿瘤活性，可以诱导细胞凋亡、自噬。
T4036	Solasodine Solancarpidine,Purapuridine,澳洲茄铵,Solasodin	Apoptosis; Others; E1/E2/E3 Enzyme; Antifungal	Apoptosis; Microbiology/Virology; Others; Ubiquitination
	Solasodine (Purapuridine) 是存在于茄科植物中的一种类固醇生物碱。它具有神经保护、降压、抗真菌、抗癌、抗动脉粥样硬化、抗雄激素和抗炎活性。
T5429	Theaflavin 3,3'-digallate 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG	Virus Protease; Antioxidant; HIV Protease; HSV	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂，IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制，可抑制 gp41 和 NS2B-3 蛋白酶的活性，并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚，有抗肿瘤作用。
T3798	Ziyuglycoside I Gouguside 7,Ziyu-glycoside I,3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester,地榆皂苷 I,苦丁冬青甙 H,Zigu-glucoside I,Kudinoside H	Apoptosis; Others	Apoptosis; Others
	Ziyuglycoside I (Gouguside 7) 是从地榆根中分离的一种天然产物。它可用作化妆品的有效成分，具有抗皱活性，并增加 I 型胶原蛋白的表达。它引发p53介导的细胞周期阻滞和凋亡，可用于三阴乳腺癌的相关研究。
T6S1917	Schisandrol B Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B	P450; Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Schisandrol B (Besigomsin) 是华中五味子的主要活性成分，具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生，也抑制 P-糖蛋白和CYP3A 的活性。
TN6771	Malabaricone B	Others	Others
	Malabaricone B 是一种源自香料的酚类物质，它通过不依赖 p53 的途径诱导肺癌细胞中的线粒体损伤。
T30969	Clitocine	Apoptosis; BCL	Apoptosis
	Clitocine 是一种来从蘑菇中提取的一种腺苷类似物，是一种有效的转录通读剂，是一种无义突变的抑制剂，具有抗癌活性，可诱导携带 p53 无义突变等位基因的细胞产生 p53 蛋白。Clitocine 通过促进 Mcl-1 降解来增强 TRAIL 介导的人结肠癌细胞凋亡。
T5S0168	Atractylenolide II 2-Atractylenolide,Asterolide,苍术内酯II	Apoptosis; ERK; p38 MAPK; Akt; STAT	Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Atractylenolide II (2-Atractylenolide) 是一种从白术干燥根茎分离的倍半萜类天然产物，具有抗增殖活性。
T5S0331	Isoliquiritin 异甘草苷,Neoisoliquritin	p53; Antifungal	Apoptosis; Microbiology/Virology
	Isoliquiritin (Neoisoliquritin) 是从甘草根中分离得到的，具有镇咳、抗抑郁作用和抗真菌活性。它还能抑制血管生成和导管形成。
T2140	Parthenolide (-)-Parthenolide,小白菊内酯	Apoptosis; Mitophagy; NF-κB; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κB
	Parthenolide ((-)-Parthenolide) 是一种从药草短舌匹菊中发现的倍半萜内酯。它抑制NF-κB 活化，有抗炎活性。它还可抑制HDAC1蛋白，但不影响其他I/II 类HDAC。
T6S1780	Protosappanin B 原苏木素B,Q-100961,FT-0689654	Apoptosis	Apoptosis
	Protosappanin B (Q-100961) 是从苏木中提取的一种多酚类天然产物，具有抗肿瘤作用。它通过激活 MDM2 依赖性泛素化过程诱导 p53 蛋白降解。它显著提高细胞活力，抑制细胞凋亡并上调生长相关蛋白 43 的表达。
T7027	EURYCOMANONE 东革阿里提取物,Pasakbumin A	Others	Others
	Eurycomanone (Pasakbumin A) 能够抑制雌激素生成过程中磷酸二酯酶和芳香酶的活性，促进精子生成。它对 HepG2 细胞具有细胞毒性，能够上调 p53 和 Bax 以及下调 Bcl-2 ，诱导细胞凋亡。它具有抗癌活性，在浓度范围内以剂量依赖性方式抑制 A549 肺癌细胞增殖从 5 到 20 微克/毫升。
T0983	Penicillamine 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine	Antibiotic	Microbiology/Virology
	Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物，是一种螯合剂，可作用于威尔逊氏病。
TN1620	Eriocalyxin B 毛萼乙素	Apoptosis; cAMP; NF-κB; STAT	Apoptosis; GPCR/G Protein; JAK/STAT signaling; NF-κB; Stem Cells
	Eriocalyxin B 是从中草药枇杷素中分离得到的一种二萜类天然产物，可诱导细胞凋亡，具有抗癌和抗炎作用。
T6717	Vanillin Lioxin,m-Methoxy-p-hydroxybenzaldehyde,香草醛,Zimco,p-Vanillin,p-Hydroxy-m-methoxybenzaldehyde,香兰素,FEMA 3107	Others; Endogenous Metabolite	Metabolism; Others
	Vanillin (Zimco) 是一种天然产物，是从香草豆中提取的单个分子，是香水，食品和药物中广泛使用的气味。
T6917	Oleuropein 洋橄榄苦甙,橄榄苦苷	Apoptosis; Aromatase; ROS; PPAR	Apoptosis; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism
	Oleuropein 在橄榄叶和油中发现的天然产物，通过 p53 依赖性途径以及 Bax 和 Bcl2基因的调控来诱导乳腺癌细胞凋亡，还抑制芳香化酶。它可通过直接抑制 PPARγ转录活性来发挥抗氧化，抗炎和抗动脉粥样硬化作用。
T5S0045	Isofraxidin 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶	MMP; ERK; p38 MAPK; TLR; COX	Immunology/Inflammation; MAPK; Neuroscience; Proteases/Proteasome
	Isofraxidin (Phytodolor) 是来自刺五加的香豆素成分，抑制MMP-7表达和人肝癌细胞侵袭。它作用于肝癌细胞，抑制ERK1/2磷酸化。它减弱iNOS 和COX-2表达，还抑制TLR4/髓样分化蛋白 2 复合物的形成。
T6S1369	Vitexin 牡荆素,Apigenin-8-C-glucoside	Antioxidant	oxidation-reduction
	Vitexin 是一种存在于多种药用植物（如榕树、螺旋藻）中的 c-糖基化的黄酮。它具有广泛的药理作用，包括抗氧化，抗癌，抗炎，抗痛觉过敏和神经保护作用。
T5S0055	Chelidonine Helidonine,Khelidonin,白屈菜碱,Stylophorin	Apoptosis; Others; Influenza Virus	Apoptosis; Microbiology/Virology; Others
	Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱，有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞，诱导 caspase 依赖和非依赖性的细胞凋亡。
T1221	Acetylcholine chloride ACh chloride,Pilofrin,氯化乙酰胆碱	Calcium Channel; Endogenous Metabolite; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Acetylcholine chloride (Pilofrin) 是一种神经递质，是胆碱能激动剂，通过刺激烟碱乙酰胆碱受体调节多巴胺能神经元活性，在体外抑制 p53 突变肽的聚集。
T2179	Triptolide PG490,NSC 163062,雷公藤甲素	Apoptosis; Mdm2; HSP; NF-κB	Apoptosis; Cytoskeletal Signaling; Metabolism; NF-κB
	Triptolide (PG490) 属于三环二萜类天然产物，是一种 NF-κB 活化的抑制剂。Triptolide 具有免疫抑制、抗风湿、抗炎、抗增殖和抗肿瘤活性。
T6S0221	Eriocitrin eriodictyol 7-rutinoside,圣草次甙,Eriodictyol-7-O-Rutinoside,Eriodictioside,圣草次甙；圣草次苷,Eriodictyol glycoside	Apoptosis; Carbonic Anhydrase	Apoptosis; Metabolism
	Eriocitrin (Eriodictyol-7-O-Rutinoside) 是从柠檬中分离出来的一种黄酮类天然产物，是强效的抗氧化剂。它通过激活线粒体涉及的内在信号传导途径来触发细胞凋亡。它通过上调 p53、cyclin A、cyclin D3 和 CDK6 使 S 期细胞周期停滞，从而抑制肝癌细胞的增殖。
TN4250	Imbricatolic acid	p53	Apoptosis
	Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells.
T79991	Condurango glycoside A
	Condurango glycoside A 作为p53激活剂，能够促进ROS的生成并且上调p53的表达。此外，Condurango glycoside A 还能够诱导HeLa细胞发生与DNA损伤相关的凋亡及过早老化。
TN1688	Ginsenoside Rs3 人参皂苷RS3	p53	Apoptosis
	Ginsenoside Rs3 induce apoptosis, is related to the elevations of p53 and p21WAF1 in the cells.
TN1354	Aaptamine	c-Myc; TNF; p53	Apoptosis; Cell Cycle/Checkpoint
	Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
T68731	Myxothiazol
	Myxothiazol is an inhibitor of mitochondrial respiratory chain complexes III. Myxothiazol induces transcription of the p53-responsive SESN2 gene that plays an important role in stress response and homeostatic regulation.
TN2123	Quercetin 3-O-(6''-galloyl)-β-D-galactopyranoside Hyperin 6''-gallate,槲皮素3-O-(6''-没食子酰基)-Β-D-半乳糖苷,Quercetin 3-O-(6''-galloyl)-beta-D-galactopyranoside	MAPK; p53	Apoptosis; MAPK
	Quercetin 3-O-(6''-galloyl)-beta-D-galactopyranoside can effectively induce apoptosis via p53, MAPKs and the mitochondrial apoptotic pathways.
TN1156	(-)-Curine	p53	Apoptosis
	(-)-Curine can inhibit viability of hepatocellular carcinoma cells in regardless of p53 status.
T75669	Odoroside A
	Odoroside A，一种自夹竹桃叶中提取的有效成分，具抗癌活性。它通过ROS/p53信号通路诱导细胞凋亡及细胞周期阻滞，进而引发肿瘤细胞死亡。
T40483	8-Aminoadenosine 8-NH2-Ado,8-氨基腺苷
	8-Aminoadenosine (8-NH2-Ado) is an RNA-directed nucleoside analogue that effectively diminishes cellular ATP levels and impedes mRNA synthesis. Furthermore, it effectively obstructs Akt/mTOR signaling, inducing autophagy and apoptosis in a p53-independent manner. Its significant antitumor activity further highlights its therapeutic potential.
TN2114	Pseudoginsenoside Rh2 拟人参皂苷RH2,拟人参皂苷 Rh2	ERK; Raf; p53	Apoptosis; MAPK
	Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for excessive activation of the Ras/Raf/ERK/p53 pathway. (20Z) -Pseudoginsenoside Rh2 and (20E)-Pseudoginsenoside Rh2 have antioxidative activity.
T13764	Lycopodine	Lipoxygenase; Caspase	Apoptosis; Metabolism; Proteases/Proteasome
	Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis. This process is mediated by caspase-3 activation. In refractory prostate cancer cells, Lycopodine triggers apoptosis by modulating 5-lipoxygenase and depolarizing the mitochondrial membrane potential, without altering p53 activity.
TN5201	Uncarinic acid E	BCL; MEK; Caspase; PI3K; Antifection; p53	Apoptosis; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome c release from the mitochondria. A mixture of uncarinic acid E and 27-O-p-(
TN4774	Physalin A	ERK; BCL; p38 MAPK; NF-κB; Androgen Receptor; ROS; JAK; JNK; STAT; p53; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Endocrinology/Hormones; Immunology/Inflammation; JAK/STAT signaling; MAPK; NF-κB; Stem Cells
	Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor ex
T38036	Lumisterol
	Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol. Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities[1]. [1]. Anyamanee Chaiprasongsuk, et al. Protective Effects of Novel Derivatives of Vitamin D 3 and Lumisterol Against UVB-induced Damage in Human Keratinocytes Involve Activation of Nrf2 and p53 Defense Mechanisms. Redox Biol. 2019 Jun;24:101206.

天然产物

Cat.No: T8678

Synonym: 萘茜,5,8-Dihydroxy-1,4-naphthoquinone,DHNQ

Target: Apoptosis

Cat.No: T5061

Synonym: 7,8-Dimethylalloxazine,光色素

Target: Others

Cat.No: T0132

Synonym: VP-16,依托泊苷,依托泊甙,VP-16-213

Target: Apoptosis, Mitophagy, Topoisomerase, Antibacterial, Antibiotic, Autophagy

Cat.No: T4036

Synonym: Solancarpidine,Purapuridine,澳洲茄铵,Solasodin

Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal

Theaflavin 3,3'-digallate

Cat.No: T5429

Synonym: 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

Ziyuglycoside I

Cat.No: T3798

Synonym: Gouguside 7,Ziyu-glycoside I,3-O-alpha-L-Arabinopyranosylpomolic acid beta-D-glucopyranosyl ester,地榆皂苷 I,苦丁冬青甙 H,Zigu-glucoside I,Kudinoside H

Target: Apoptosis, Others

Cat.No: T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Cat.No: TN6771

Target: Others

Cat.No: T30969

Target: Apoptosis, BCL

Atractylenolide II

Cat.No: T5S0168

Synonym: 2-Atractylenolide,Asterolide,苍术内酯II

Target: Apoptosis, ERK, p38 MAPK, Akt, STAT

Cat.No: T5S0331

Synonym: 异甘草苷,Neoisoliquritin

Target: p53, Antifungal

Cat.No: T2140

Synonym: (-)-Parthenolide,小白菊内酯

Target: Apoptosis, Mitophagy, NF-κB, HDAC, Autophagy

Protosappanin B

Cat.No: T6S1780

Synonym: 原苏木素B,Q-100961,FT-0689654

Target: Apoptosis

Cat.No: T7027

Synonym: 东革阿里提取物,Pasakbumin A

Target: Others

Cat.No: T0983

Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Target: Antibiotic

Cat.No: TN1620

Synonym: 毛萼乙素

Target: Apoptosis, cAMP, NF-κB, STAT

Cat.No: T6717

Synonym: Lioxin,m-Methoxy-p-hydroxybenzaldehyde,香草醛,Zimco,p-Vanillin,p-Hydroxy-m-methoxybenzaldehyde,香兰素,FEMA 3107

Target: Others, Endogenous Metabolite

Cat.No: T6917

Synonym: 洋橄榄苦甙,橄榄苦苷

Target: Apoptosis, Aromatase, ROS, PPAR

Cat.No: T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶

Target: MMP, ERK, p38 MAPK, TLR, COX

Cat.No: T6S1369

Synonym: 牡荆素,Apigenin-8-C-glucoside

Target: Antioxidant

Cat.No: T5S0055

Synonym: Helidonine,Khelidonin,白屈菜碱,Stylophorin

Target: Apoptosis, Others, Influenza Virus

Acetylcholine chloride

Cat.No: T1221

Synonym: ACh chloride,Pilofrin,氯化乙酰胆碱

Target: Calcium Channel, Endogenous Metabolite, AChR

Cat.No: T2179

Synonym: PG490,NSC 163062,雷公藤甲素

Target: Apoptosis, Mdm2, HSP, NF-κB

Cat.No: T6S0221

Synonym: eriodictyol 7-rutinoside,圣草次甙,Eriodictyol-7-O-Rutinoside,Eriodictioside,圣草次甙；圣草次苷,Eriodictyol glycoside

Target: Apoptosis, Carbonic Anhydrase

Imbricatolic acid

Cat.No: TN4250

Target: p53

Condurango glycoside A

Cat.No: T79991

Ginsenoside Rs3

Cat.No: TN1688

Synonym: 人参皂苷RS3

Target: p53

Cat.No: TN1354

Target: c-Myc, TNF, p53

Cat.No: T68731

Quercetin 3-O-(6''-galloyl)-β-D-galactopyranoside

Cat.No: TN2123

Synonym: Hyperin 6''-gallate,槲皮素3-O-(6''-没食子酰基)-Β-D-半乳糖苷,Quercetin 3-O-(6''-galloyl)-beta-D-galactopyranoside

Target: MAPK, p53

Cat.No: TN1156

Target: p53

Cat.No: T75669

8-Aminoadenosine

Cat.No: T40483

Synonym: 8-NH2-Ado,8-氨基腺苷

Pseudoginsenoside Rh2

Cat.No: TN2114

Synonym: 拟人参皂苷RH2,拟人参皂苷 Rh2

Target: ERK, Raf, p53

Cat.No: T13764

Target: Lipoxygenase, Caspase

Uncarinic acid E

Cat.No: TN5201

Target: BCL, MEK, Caspase, PI3K, Antifection, p53

Cat.No: TN4774

Target: ERK, BCL, p38 MAPK, NF-κB, Androgen Receptor, ROS, JAK, JNK, STAT, p53, Autophagy

Cat.No: T38036

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02228	p53 Protein, Cynomolgus, Recombinant tumor protein p53,p53,TP53	Cynomolgus	E. coli
	p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family. It contains transcription activation, DNA-binding, and oligomerization domains. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 (TP53) is a transcription factor whose protein levels and post-translational modification state alter in response to cellular stress (such as DNA damag...
TMPK-01508	HLA-A02:01&B2M&P53* WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi) TP53,Antigen NY-CO-13,P53,MHC,HLA-A,BCC7,L...	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01552	HLA-A02:01&B2M&P53* R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated TP53,TRP53,HLA-A,MHC,Antigen NY-CO-13,BCC7...	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01509	HLA-A02:01&B2M&P53* WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi) TRP53,HLA-A,TP53,LFS1,P53,MHC,FLJ...	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01531	HLA-A02:01&B2M&P53* R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi) Antigen NY-CO-13,MHC,FLJ92943,TRP53,HLA-A,BCC7,T	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01532	HLA-A02:01&B2M&P53* R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi) Antigen NY-CO-13,BCC7,FLJ92943,HLA-A,LFS1,P53,T...	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01538	HLA-A02:01&B2M&P53* WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,LFS1,Antigen NY-CO-13,HLA-A,BCC7,TP53,TRP53...	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01437	HLA-A02:01&B2M&P53* R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled FLJ92943,HLA-A,TP53,Antigen NY-CO-13,TRP53...	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01442	HLA-A02:01&B2M&P53* WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled HLA-A,P53,TP53,LFS1,MHC,BCC7,TRP53	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPY-01125	MDMX Protein, Human, Recombinant (His) MRP1,MDM4, p53 regulator,HDMX,MDMX	Human	E. coli
	MDM4 (MDM4 Regulator Of P53, also known as MDMX) is a Protein Coding gene. This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus and shows structural similarity to p53-binding protein MDM2. MDM4 is a promising target for cancer therapy, as it is undetectable in most normal adult tissues but often upregulated in cancer cells to dampen p53 tumor-suppressor function. MDM4, an essential negative regulator of the P53 tumor ...
TMPY-01561	PIG3 Protein, Human, Recombinant (His) TP53I3,PIG3,tumor protein p53 inducible pr...	Human	E. coli
	Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of...
TMPH-03264	p53 Protein, Rat, Recombinant (His)	Rat	E. coli
	Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 ex...
TMPY-03601	PDRG1 Protein, Human, Recombinant (His) PDRG,p53 and DNA-damage regulated 1,C20orf126	Human	E. coli
	PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chaperone-mediated protein folding. PDRG1 is overexpressed in tumors relative to normal tissues. Its expression is upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to their respective matched normal tissue...
TMPH-02574	p53 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 ex...
TMPH-01075	p53 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	p53 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 59.7 kDa and the accession number is P04637.
TMPJ-00022	LGALS7 Protein, Human, Recombinant Galectin-7,Gal-7,LGALS7,PI7,PIG1,LGALS7B,p53-Induce...	Human	E. coli
	The Galectin family of proteins, with specificity for Nacetyllactosamine containing glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs).They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. Although they are localized primarily in the cytoplasm and lack a classical signal peptide; they can be secreted ...
TMPY-05896	Influenza A H3N2 (A/swine/Thailand/CU-P53/2012) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H3N2	HEK293 Cells
	Influenza A H3N2 (A/swine/Thailand/CU-P53/2012) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.9 kDa and the accession number is S4TZ09.
TMPH-01520	HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc)	HIV-1	E. coli
	HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.8 kDa and the accession number is P0C1P2.
TMPY-02527	p53R2 Protein, Human, Recombinant (His) P53R2,MTDPS8A,MTDPS8B,ribonucleotide reductase M2 B...	Human	E. coli
	Ribonucleoside reductase subunit M2B, also known as RRM2B or p53R2, is an enzyme belonging to the iron-dependent ribonucleotide reductase (RNR) enzyme family which is essential for DNA synthesis. Ribonucleotide reductase (RNR) is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides and plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair. RRM2B is a phospho...
TMPY-00369	LY6D Protein, Human, Recombinant (mFc) E48,lymphocyte antigen 6 complex, locus D,Ly-6D	Human	HEK293 Cells
	LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. The expression of LY6D is induced in MCF10A cells by X-ray irradiation. The induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2, and p53. This method is a new Ab-directed proteomic strategy for the analysis of membrane protein...
TMPY-02030	CD82 Protein, Human, Recombinant (His) CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPH-01659	MAGEA4 Protein, Human, Recombinant (A173T, His & Myc)	Human	E. coli
	Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis.
TMPY-00151	Alpha SNAP Protein, Human, Recombinant (His) N-ethylmaleimide-sensitive factor attachment protein, alpha,...	Human	E. coli
	NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. NAPA overexpression decreased the ubiquitination and degradation of s...
TMPH-01658	MAGEA4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis.
TMPJ-01211	EDA2R Protein, Mouse, Recombinant (His) EDA-A2R,Tumor necrosis factor receptor superfamily member XE...	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR superfamily. EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. EDA2R is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, EDA2R can associate with Fas and induce EDA‑A2 ...
TMPY-00648	UNC5A Protein, Human, Recombinant (hFc) UNC5H1,unc-5 homolog A (C. elegans)	Human	HEK293 Cells
	The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,...
TMPY-00999	UNC5A Protein, Human, Recombinant (His) unc-5 homolog A (C. elegans),UNC5H1	Human	HEK293 Cells
	The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis. UNC5A Protein, Human,...
TMPH-02221	TRIM24 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apopt...
TMPJ-01278	SENP8 Protein, Human, Recombinant (His) DEN1,Protease Cysteine 2,NEDP1,Sentrin-Specific Protease 8,D...	Human	E. coli
	Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.
TMPY-04904	Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc)	ZIKV	HEK293 Cells
	Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibitors can block the apoptosis induced by ZIKV-M in hNPCs.
TMPY-02211	USP5 Protein, Human, Recombinant (His) ISOT,ubiquitin specific peptidase 5 (isopeptidase T)	Human	Baculovirus Insect Cells
	Ubiquitin carboxyl-terminal hydrolase 5, also known as Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thiolesterase 5, Ubiquitin-specific-processing protease 5, ISOT and USP5, is a member of the peptidase C19 family. USP5 contains 2 UBA domains and one UBP-type zinc finger. The UBP-type zinc finger domain interacts selectively with an unmodified C-terminus of the proximal ubiquitin. Both UBA domains are involved in polyubiquitin recognition. The UBP-type zinc finger domain crystallizes as ...
TMPJ-00675	ZNHIT1 Protein, Human, Recombinant (His) ZNFN4A1,CGBP1,inc finger HIT domain-containing protein 1,cyc...	Human	E. coli
	ZNHIT1 belongs to the ZNHIT1 family and contains one HIT-type zinc finger. It can be phosphorylated on Thr by MAPK11 or MAPK14. ZNHIT1 is a component of the chromatin-remodeling SRCAP complex, which is composed of at least SRCAP, DMAP, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. ZNHIT1 may play a role in p53-mediated apoptosis induction.
TMPJ-00703	Gankyrin Protein, Human, Recombinant PSMD10,Gankyrin,26S Proteasome Non-ATPase Regulatory Subunit...	Human	E. coli
	Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.
TMPH-03269	COMMD5 Protein, Rat, Recombinant (His & Myc) COMM domain-containing protein 5,COMMD5,Hypertension-related...	Rat	E. coli
	May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
TMPJ-00697	NOL3 Protein, Human, Recombinant (GST) Nop30,Myp,NOP,Apoptosis Repressor With CARD,Nucleolar Protei...	Human	E. coli
	Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in RNA splicing.Isoform 2 may inhibit apoptosis.It has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53.
TMPJ-00571	UBE2D3 Protein, Human, Recombinant Ubiquitin-protein ligase D3,Ubiquitin-conjugating enzyme E2(...	Human	E. coli
	UBE2D3 is an enzyme that belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.
TMPY-03976	EEF1E1 Protein, Human, Recombinant (His) eukaryotic translation elongation factor 1 ε 1,P18,eukaryoti...	Human	E. coli
	EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. It is comprised of a bifunctional glutamyl-prolyl-tRNA synthase, the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl and aspartyl-tRNA synthases, and three auxiliary proteins, EEF1E1/p18, AIMP2/p38 and AIMP1/p43. EEF1E1 also plays a positive role in ATM/AT...
TMPH-02549	FHIT Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monop...
TMPY-02135	S100A16 Protein, Human, Recombinant S100F,DT1P1A7,S100 calcium binding protein A16,MGC17528,AAG1...	Human	E. coli
	S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has be...
TMPJ-00464	APE Protein, Human, Recombinant APEX,Apurinic-Apyrimidinic Endonuclease 1,APEN,DNA-(Apurinic...	Human	E. coli
	Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete repair. APE1 stimulates the DNA binding activity of many transcription factors, which participate in cancer promotion and progression. APE1 regulates the redox state of multiple transcription factors, such as c-Jun, c-Fos, NF-kB, p53. APEN is also involved in calcium-dependent down...
TMPY-04768	PRPS2 Protein, Human, Recombinant (His) PRPS2,PRSII,phosphoribosyl pyrophosphate synthetase 2	Human	E. coli
	PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine...
TMPJ-01456	Mucin-17/MUC17 Protein, Human, Recombinant (His) Mucin-17, MUC-17, MUC17, MUC3, MUC-3	Human	HEK293 Cells
	Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression ...
TMPY-02651	p63 Protein, Human, Recombinant (His & GST) p40,TP53L,RHS,B(p51A),p51,KET,NBP,B(p51B),OFC8,tumo...	Human	Baculovirus Insect Cells
	Tumor protein p63 is a protein also known as transformation-related protein 63, TP63, and p63. Tumor protein p63 / p63 is a member of the p53 family of transcription factors whose members P53, p63, and p73 have similar features in their gene structures and functions. An animal model, p63-/- mice has been useful in difining the role p63 plays in the development and maintenance of stratified epithelial tissues. This p63 encoding protein p63 has a dramatic impact on replenishment of cutaneous epith...
TMPJ-00999	UBE2D1 Protein, Human, Recombinant (GST) Ubiquitin-conjugating enzyme E2(17)KB 1,UB,UbcH5,UBC5A,Stimu...	Human	E. coli
	Ubiquitin-conjugating enzyme E2 D1（UBE2D1）belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transc...
TMPH-01552	IRF1 Protein, Human, Recombinant (GST & His)	Human	Baculovirus Insect Cells
	Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired imm...
TMPY-03443	NDRG1 Protein, Human, Recombinant (His) TARG1,PROXY1,RIT42,NDR1,DRG1,RTP,TDD5,CMT4D,CAP43,NMSL,N-myc...	Human	E. coli
	NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive pro...
TMPY-03658	ETHE1 Protein, Human, Recombinant (His) YF13H12,HSCO,ethylmalonic encephalopathy 1	Human	E. coli
	ETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. ETHE1 can suppresses p53-induced apoptosis by preventing nuclear localization of RELA. Mutations in ETHE1 gene result in ethylmalonic encephalopathy. Ethylmalonic en...
TMPY-02150	GADD45A Protein, Human, Recombinant (His & GST) GADD45,growth arrest and DNA-damage-inducible, alpha,growth ...	Human	Baculovirus Insect Cells
	GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulation, DNA repair and genomic stability, apoptosis, and immune responses. The GADD45 Family of genes is rapidly induced by different stressors, including differentiation-inducing cytokines, and there is a large body of evidence that their cognate proteins are key players in cellular ...
TMPJ-00696	NOL3 Protein, Human, Recombinant Apoptosis Repressor With CARD,Nucleolar Protein of 30 kDa,Nu...	Human	E. coli
	Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in RNA splicing. Isoform 2 functions as an apoptosis repressor that blocks multiple modes of cell death. It inhibits extrinsic apoptotic pathways through two different ways. Firstly, it by interacting with FAS and FADD upon FAS activation blocking death-inducing signaling complex ...
TMPY-04550	JNK2 Protein, Human, Recombinant (His) JNK2α,SAPK1a,PRKM9,JNK2β,JNK2,SAPK,JNK2BETA,mitogen-activate...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating some transcription factors, such as c-Jun and ATF2. The crystal structure of human JNK2 complexed with an indazole inhibitor by applying a high-throughput protein engineering and surface-site mutagenesis approach. A n...
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重组蛋白

p53 Protein, Cynomolgus, Recombinant

Cat.No: TMPY-02228

Species: Cynomolgus

Expression System: E. coli

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01508

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01552

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01509

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01531

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01532

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01538

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01437

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Cat.No: TMPK-01442

Species: Human

Expression System: HEK293 Cells

MDMX Protein, Human, Recombinant (His)

Cat.No: TMPY-01125

Species: Human

Expression System: E. coli

PIG3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01561

Species: Human

Expression System: E. coli

p53 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03264

Species: Rat

Expression System: E. coli

PDRG1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03601

Species: Human

Expression System: E. coli

p53 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02574

Species: Mouse

Expression System: E. coli

p53 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01075

Species: Human

Expression System: E. coli

LGALS7 Protein, Human, Recombinant

Cat.No: TMPJ-00022

Species: Human

Expression System: E. coli

Influenza A H3N2 (A/swine/Thailand/CU-P53/2012) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-05896

Species: H3N2

Expression System: HEK293 Cells

HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc)

Cat.No: TMPH-01520

Species: HIV-1

Expression System: E. coli

p53R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02527

Species: Human

Expression System: E. coli

LY6D Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00369

Species: Human

Expression System: HEK293 Cells

CD82 Protein, Human, Recombinant (His)

Cat.No: TMPY-02030

Species: Human

Expression System: HEK293 Cells

MAGEA4 Protein, Human, Recombinant (A173T, His & Myc)

Cat.No: TMPH-01659

Species: Human

Expression System: E. coli

Alpha SNAP Protein, Human, Recombinant (His)

Cat.No: TMPY-00151

Species: Human

Expression System: E. coli

MAGEA4 Protein, Human, Recombinant (His)

Cat.No: TMPH-01658

Species: Human

Expression System: HEK293 Cells

EDA2R Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01211

Species: Mouse

Expression System: HEK293 Cells

UNC5A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00648

Species: Human

Expression System: HEK293 Cells

UNC5A Protein, Human, Recombinant (His)

Cat.No: TMPY-00999

Species: Human

Expression System: HEK293 Cells

TRIM24 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02221

Species: Human

Expression System: E. coli

SENP8 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01278

Species: Human

Expression System: E. coli

Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc)

Cat.No: TMPY-04904

Species: ZIKV

Expression System: HEK293 Cells

USP5 Protein, Human, Recombinant (His)

Cat.No: TMPY-02211

Species: Human

Expression System: Baculovirus Insect Cells

ZNHIT1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00675

Species: Human

Expression System: E. coli

Gankyrin Protein, Human, Recombinant

Cat.No: TMPJ-00703

Species: Human

Expression System: E. coli

COMMD5 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03269

Species: Rat

Expression System: E. coli

NOL3 Protein, Human, Recombinant (GST)

Cat.No: TMPJ-00697

Species: Human

Expression System: E. coli

UBE2D3 Protein, Human, Recombinant

Cat.No: TMPJ-00571

Species: Human

Expression System: E. coli

EEF1E1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03976

Species: Human

Expression System: E. coli

FHIT Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02549

Species: Mouse

Expression System: E. coli

S100A16 Protein, Human, Recombinant

Cat.No: TMPY-02135

Species: Human

Expression System: E. coli

APE Protein, Human, Recombinant

Cat.No: TMPJ-00464

Species: Human

Expression System: E. coli

PRPS2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04768

Species: Human

Expression System: E. coli

Mucin-17/MUC17 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01456

Species: Human

Expression System: HEK293 Cells

p63 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02651

Species: Human

Expression System: Baculovirus Insect Cells

UBE2D1 Protein, Human, Recombinant (GST)

Cat.No: TMPJ-00999

Species: Human

Expression System: E. coli

IRF1 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-01552

Species: Human

Expression System: Baculovirus Insect Cells

NDRG1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03443

Species: Human

Expression System: E. coli

ETHE1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03658

Species: Human

Expression System: E. coli

GADD45A Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02150

Species: Human

Expression System: Baculovirus Insect Cells

NOL3 Protein, Human, Recombinant

Cat.No: TMPJ-00696

Species: Human

Expression System: E. coli

JNK2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04550

Species: Human

Expression System: Baculovirus Insect Cells

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