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Cat. No. Product Name
L9700 内质网应激化合物库

193 compounds
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选;
L3900 DNA 损伤和修复分子库

937 compounds
937 个与 DNA 损伤和修复紧密相关的化合物集合,是高通量筛选,高内涵筛选的良好载体;
L2195 抗前列腺癌化合物库

2096 compounds
2096 种与前列腺癌相关的化合物,可以用于高通量和高内涵筛选
L3980 DNA损伤/修复库Plus

667 compounds
667 种 DNA 损伤/修复靶向、结构新颖的化合物;
L6730 抗病毒中药单体化合物库

270 compounds
270 种具有抗病毒活性的中药单体集合,是药物开发、药理研究的有效工具;
L8700 铁死亡化合物库

800 compounds
800 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选;
L8110 细胞重编程化合物库

1840 compounds
1840 种重编程信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选
L8200 抗衰老化合物库

3324 compounds
3324 个抗衰老化合物的独特集合,可用于高通量筛选和高内涵筛选;
L6610 抗感染天然产物库

1070 compounds
1070 个抗感染相关的天然产物集合,是药物开发、药理研究的有效工具;
L6750 活血化瘀中药单体库

588 compounds
588种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。
L1100 蛋白酶抑制剂库

344 compounds
344 种已知的小分子蛋白酶抑制剂的特有集合,可用于高通量筛选和高内涵筛选;
L7900 成骨分子库

320 compounds
320 种成骨相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L9000 细胞凋亡化合物库

1796 compounds
1796 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选;
L5700 精选片段库

246 compounds
246 个片段小分子的独特集合,可用于基于片段的筛选和药物发现(FBDD);
L6120 黄酮类天然产物库

477 compounds
477 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选;
L7600 趋化因子抑制剂库

59 compounds
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选;
L6720 抗COVID-19中药单体库

1162 compounds
根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂,收集了1162 种相关中药来源的单体化合物,可用于高通量和高内涵筛选,是抗新冠病毒药物研发的良好工具;
L1710 抗COVID-19化合物库

1160 compounds
1160 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选;
L6740 抗结直肠癌中药单体化合物库

386 compounds
386 种抗结直肠癌相关的中药单体集合,是药物开发、药理研究的有效工具;

化合物库

内质网应激化合物库
Cat.No: L9700
Compounds: 193
DNA 损伤和修复分子库
Cat.No: L3900
Compounds: 937
抗前列腺癌化合物库
Cat.No: L2195
Compounds: 2096
DNA损伤/修复库Plus
Cat.No: L3980
Compounds: 667
抗病毒中药单体化合物库
Cat.No: L6730
Compounds: 270
铁死亡化合物库
Cat.No: L8700
Compounds: 800
细胞重编程化合物库
Cat.No: L8110
Compounds: 1840
抗衰老化合物库
Cat.No: L8200
Compounds: 3324
抗感染天然产物库
Cat.No: L6610
Compounds: 1070
活血化瘀中药单体库
Cat.No: L6750
Compounds: 588
蛋白酶抑制剂库
Cat.No: L1100
Compounds: 344
成骨分子库
Cat.No: L7900
Compounds: 320
细胞凋亡化合物库
Cat.No: L9000
Compounds: 1796
精选片段库
Cat.No: L5700
Compounds: 246
黄酮类天然产物库
Cat.No: L6120
Compounds: 477
趋化因子抑制剂库
Cat.No: L7600
Compounds: 59
抗COVID-19中药单体库
Cat.No: L6720
Compounds: 1162
抗COVID-19化合物库
Cat.No: L1710
Compounds: 1160
抗结直肠癌中药单体化合物库
Cat.No: L6740
Compounds: 386
Cat. No. Product Name Target Signaling Pathways
T22774L eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA)

Others Others
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) 是延伸因子 1 亚基。真核翻译延伸因子 1 alpha 1 (EEF1A1) 编码延伸因子 alpha 亚基的同种型- 1 复合物,负责将氨酰 tRNA 酶促递送至核糖体。这种亚型(α 1)在脑、胎盘、肺、肝、肾和胰腺中表达,另一种亚型(α 2)在脑、心脏和骨骼肌中表达。这种亚型在 66% 的 Felty 综合征患者中被鉴定为自身抗原。已发现该基因在许多染色体上具有多个拷贝,其中一些(如果不是全部)代表不同的假基因。
T72013 Epigenetic Multiple Ligand

Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing either apoptosis or granulocytic differentiation.
TP2248 ferritin heavy chain fragment [Multiple species]

Others Others
Ferritin is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. Invertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21 kDA respectively. The ferritin fou
TP2269 MAP kinase fragment [Multiple species]

Others Others
This Mitogen-activated protein kinase (MAP kinase) fragment has a peptide sequence of Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu. The MAP kinases are serine/threonine-specific protein kinases belonging to the CMGC (CDK/MAPK/GSK3/CLK) kinase group.
T22774 eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]

Others Others
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed
T6800 CCF642

AC1LYELL

Others Others
CCF642 (AC1LYELL) 是蛋白质二硫键异构酶抑制剂(IC50:2.9 μM)。它在多发性骨髓瘤细胞中引起急性内质网应激,并伴随凋亡诱导的钙释放,表现出广泛的抗多发性骨髓瘤作用。
T9745 Elevenostat

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
Elevenostat 是有效的HDAC11选择性抑制剂 (IC50=0.235 µM)。Elevenostat 具有抗多发性骨髓瘤的活性。
TP2315 glatiramer Acetate

Others Others
Glatiramer acetate 是髓鞘碱性蛋白的合成类似物和免疫调节剂,可用于多发性硬化症的研究。它能够诱导 T 辅助细胞 2 的特异性抑制细胞迁移到大脑并导致原位旁观者抑制。它能够于 MHC 分子强而杂乱的结合,因此与各种髓鞘抗原竞争,使其呈现给 T 细胞。
T22277 BMS-P5

PAD Chromatin/Epigenetic
BMS-P5 是一种特异性具有口服活性的肽精氨酸二亚胺酶 4抑制剂。它可阻断多发性骨髓瘤诱导的 NET 形成,并延缓肿瘤进程。
T10096L Voruciclib

CDK Cell Cycle/Checkpoint
Voruciclib 是一种具有口服活性和选择性 CDK 抑制剂,Ki 为 0.626 nM-9.1 nM。它在多种弥漫性大 B 细胞淋巴瘤模型中抑制 MCL-1 的表达。它有效阻断 MCL-1 的转录调节子 CDK9。
T5484 GSK467

Histone Demethylase; Histone Methyltransferase Chromatin/Epigenetic
GSK467 是一种有效的、选择性的 KDM5 (JARID1) 抑制剂,Ki 值为10 nM。
T3971 CASIN

Pirl1-related Compound 2

CDK; STAT; Ras Cell Cycle/Checkpoint; GPCR/G Protein; JAK/STAT signaling; MAPK; Stem Cells
CASIN (Pirl1-related Compound 2) 是选择性GTPase Cdc42抑制剂,IC50值是 2 uM。
T9370 dCBP-1

Epigenetic Reader Domain; Ligand for E3 Ligase Chromatin/Epigenetic; PROTAC
dCBP-1 是基于Cereblon 配体的p300/CBP 的选择性双功能降解剂。dCBP-1可以有效的杀死多发性骨髓瘤细胞,并降低驱动 MYC 表达的致癌增强子活性。
T6796 CB-5083

CB5083,CB 5083

p97 Ubiquitination
CB-5083 是一种有效的、选择性的、可口服的 p97 AAA ATPase 抑制剂,IC50为 11 nM。
T4283 SRI-011381

TGF-beta/Smad Stem Cells
SRI011381 是口服具有活力的 TGF-β信号通路的激活剂,具有神经保护活性。
T22922 Lenalidomide hemihydrate

TNF; Ligand for E3 Ligase; Molecular Glues Apoptosis; PROTAC
Lenalidomide hemihydrate 是 Thalidomide 的衍生物,也是具有口服活性免疫调节剂,以分子胶的方式作用。它是泛素 E3 连接酶 cereblon 的配体,通过 CRBN-CRL4 泛素连接酶对两种淋巴转录因子 IKZF1 和 IKZF3 进行选择性泛素化和降解。
T9573 GSK3685032

DNA Methyltransferase Chromatin/Epigenetic
GSK-3685032 是一种非时间依赖、非共价、选择性的、可逆的DNMT1抑制剂,IC50=0.036 μM。它诱导 DNA 甲基化丧失、转录激活和癌细胞生长抑制。
T22277L BMS-P5 free base

PAD Chromatin/Epigenetic
BMS-P5 free base 是一种特异性,可口服的肽精氨酸二亚胺酶抑制剂,可阻断多发性骨髓瘤诱导的 NET 形成,并延缓肿瘤进程。
T41290 MST-312

Telomerase Inhibitor IX

Telomerase DNA Damage/DNA Repair
MST-312 (Telomerase Inhibitor IX) 是绿茶表没食子儿茶素没食子酸酯 (EGCG) 的衍生物。MST-312 是 telomerase 抑制剂,可用于肿瘤的研究,如多发性骨髓瘤 (MM)。
T0802 Procaine hydrochloride

Novocaine HCl,Procaine HCl,盐酸普鲁卡因

Histone Demethylase; 5-HT Receptor; DNA/RNA Synthesis; Sodium Channel; NMDAR; AChR Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
Procaine hydrochloride (Novocaine HCl) 是DNA 脱甲基剂,是一种苯甲酸衍生物,具有局部麻醉和抗心律失常特性。
T12871 Talmapimod

他匹莫德,SCIO-469

p38 MAPK MAPK
Talmapimod (SCIO-469) 是 选择性的,具有口服活性的,ATP 竞争性的 p38α抑制剂,对 p38α和 p38β的 IC50 值分别是 9 nM 和90 nM。Talmapimod 在 20 个其他激酶 (包括其他 MAPKs) 上显示出至少 2000 倍的选择性。
T4031 S1p receptor agonist 1

S1p-receptor-agonist-1

S1P Receptor; LPL Receptor GPCR/G Protein
S1p receptor agonist 1 (S1p-receptor-agonist-1) 是有口服活性的S1P 受体激动剂,具有诱导 S1P1 内化的活性,EC50为9.83 nM。它有潜力用于关节炎和实验性自身免疫性脑炎)的相关研究。
T13408 ZK824190

Others; Serine Protease Others; Proteases/Proteasome
ZK824190 是具有口服活性尿激酶型纤溶酶原激活剂 (uPA) 选择性抑制剂,对 uPA,tPA 和 Plasmin 的IC50分别为 237,1600 和 1850 nM。ZK824190在多发性硬化症中有研究价值。
T8342 BRD9876

6-叔丁基-2,3-二氰基萘

Others; Kinesin; Microtubule Associated Cytoskeletal Signaling; Others
BRD9876 是一种 MM1S 生长的选择性抑制剂,可将驱动蛋白 5 锁定在增强微管结合的状态,从而导致 MT 的捆绑和稳定。它特异性靶向微管结合的 Eg5,选择性抑制 CD34 细胞的骨髓瘤,有用于多发性骨髓瘤的研究潜力。
T3661 Citarinostat

ACY241,HDAC-IN-2

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
Citarinostat (ACY241) 是一种强效、选择性和口服组蛋白脱乙酰酶 (HDAC) 抑制剂,具有抗肿瘤活性,对 HDAC1、HDAC2、HDAC3、HDAC6 和 HDAC8 的 IC50分别为 35、45、46、2.6 和 137 nM。
T6403 Siponimod

辛波莫德,BAF-312

S1P Receptor; LPL Receptor GPCR/G Protein
Siponimod (BAF-312) 是有效,选择性的鞘氨醇-1-磷酸 (S1P)受体调节剂,对 S1P1 和 S1P5 受体具有特异性,EC50 分别为 0.39 nM 和 0.98 nM。 BAF312 对 S1P1 和 S1P5 受体的特异性比 S1P2、S1P3 和 S1P4 受体高 1000 倍以上。
T9125 Tolebrutinib

PRN2246,SAR442168

BTK Angiogenesis; Tyrosine Kinase/Adaptors
Tolebrutinib (PRN2246) 是一种选择性、有效的、具有口服活性、可透过血脑屏障的布鲁顿氏酪氨酸激酶抑制剂,能够作用于 Ramos B 细胞 (IC50:0.4 nM)、HMC 小胶质细胞 (IC50:0.7 nM)。它对中枢神经系统免疫具有功效。它可用于多发性硬化症的研究。
T7779 Nelfinavir

AG1341,甲磺酸萘非那韦

HIV Protease Microbiology/Virology; Proteases/Proteasome
Nelfinavir (AG1341) 是一种口服活性的 HIV-1 蛋白酶抑制剂,用于抑制 HIV 感染,是一种广谱抗癌剂。
T8719 SC99

Apoptosis; JAK; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
SC99 是一种口服有效选择性STAT3抑制剂,靶向 JAK2-STAT3 途径,抑制血小板活化和聚集,有抗骨髓瘤和抗血栓活性。它结合在 JAK2 的 ATP 结合袋中,抑制 JAK2 和 STAT3 的磷酸化。
T6312 R547

Ro 4584820

Apoptosis; GSK-3; PKA; CDK Apoptosis; Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
R547 (Ro 4584820) 是一种口服有效,选择性, ATP 竞争性CDK 抑制剂,对 CDK1/cyclin B、 CDK2/cyclin E 和 CDK4/cyclin D1 作用的Ki 值分别为 2 nM、3 nM、1 nM。
T6561 Laquinimod

LAQ,ABR-215062,拉喹莫德

Apoptosis; Others; NF-κB Apoptosis; NF-κB; Others
Laquinimod (LAQ) 是一种免疫调节剂,可预防中枢神经系统的神经变性和炎症。
T7791 Iberdomide

CC-220

Apoptosis; Ligand for E3 Ligase Apoptosis; PROTAC
Iberdomide (CC-220) 是一种口服有效的 cereblon E3 连接酶调节剂,对 cereblon 结合亲和力的 IC50约为150 nM。它是沙利度胺的衍生物,具有抗肿瘤和免疫刺激活性。
T1642 Lenalidomide

来那度胺,CC-5013

Apoptosis; TNF; Ligand for E3 Ligase; Molecular Glues Apoptosis; PROTAC
Lenalidomide (CC-5013) 是 Thalidomide 的衍生物,也是具有口服活性免疫调节剂,以分子胶的方式作用。它是泛素 E3 连接酶 cereblon (CRBN) 的配体,可通过 CRBN-CRL4 泛素连接酶对两种淋巴转录因子 IKZF1 和 IKZF3 进行选择性泛素化和降解。
T6923 Ozanimod

奥扎莫德,RPC-1063

S1P Receptor; LPL Receptor GPCR/G Protein
Ozanimod (RPC-1063) 是一种选择性S1P1和S1P5受体激动剂,在[35S]-GTPγS 结合实验中,EC50分别为 410 pM 和 11 nM。它可研究治疗克罗恩病、溃疡性结肠炎、多发性硬化症和复发性多发性硬化症的试验。
T1979 AVN-944

VX-944

Dehydrogenase Metabolism
AVN-944 (VX-944) 是一种选择性的、非竞争性 IMPDH 抑制剂,对IMPDH1和IMPDH2的Ki=为6-10nM。
T4134 OTS514 hydrochloride

OTS-514 hydrochloride,OTS514 hydrochloride(1338540-63-8(free base))

Apoptosis; TOPK Apoptosis; MAPK
OTS514 hydrochloride 是一种高效的TOPK 抑制剂,IC50为 2.6 nM。它可强效抑制 TOPK 阳性的肿瘤细胞生长,诱导细胞周期停滞和凋亡。
T6001 Nelfinavir Mesylate

Viracept,Nelfin,AG1343,AG 1343 Mesylate,甲磺酸奈非那韦

HIV Protease Microbiology/Virology; Proteases/Proteasome
Nelfinavir Mesylate (Viracept) 是一种口服活性的 HIV-1蛋白酶抑制剂,用于抑制 HIV 感染,是一种广谱抗癌剂。
T5129 SRI-011381 hydrochloride

SRI-011381 hydrochloride [1629138-41-5(free base)]

TGF-beta/Smad Stem Cells
SRI-011381 hydrochloride 是口服具有活力的TGF-β信号通路的激活剂,具有神经保护活性。
T21503 (E/Z)-Zotiraciclib

(E/Z)-TG02,(E/Z)-SB1317

FLT; JAK; CDK Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
(E/Z)-Zotiraciclib ((E/Z)-TG02) 是一种 CDK2、JAK2和FLT3的抑制剂,IC50分别为 13、73 和 56 nM。
T6079 NVP-ADW742

ADW742,ADW,GSK 552602A

Apoptosis; IGF-1R Apoptosis; Tyrosine Kinase/Adaptors
NVP-ADW742 (ADW) 是一种具有口服活性,选择性的IGF-1R 酪氨酸激酶抑制剂,IC50为 0.17 μM。它抑制胰岛素受体,IC50为 2.8 μM,在肿瘤细胞中诱导多效性抗增殖/促凋亡。
T2558 Cladribine

2-chlorodeoxyadenosine,克拉屈滨,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA

Apoptosis; Adenosine deaminase Apoptosis; Metabolism
Cladribine (2CdA) 是一种嘌呤核苷类似物,是具有口服活性的腺苷脱氨酶抑制剂。它能作为 DNA 合成的抑制剂,可阻断受损 DNA 的修复。它可抑制 DNA 甲基化,具有抗淋巴瘤活性,可研究血液恶性肿瘤和多发性硬化。
T2241 Alisertib

MLN 8237,4-[[9-氯-7-(2-氟-6-甲氧基苯基)-5H-嘧啶并[5,4-D][2]苯并氮杂卓-2-基]氨基]-2-甲氧基苯甲酸

Apoptosis; Aurora Kinase; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic
Alisertib (MLN 8237) 是一种口服活性和选择性的Aurora A 激酶抑制剂,IC50值为 1.2 nM。它通过靶向白血病细胞中的AKT/mTOR/AMPK/p38途径诱导其凋亡和自噬,具有抗肿瘤活性。
T1776 Plerixafor

普乐沙福,JM3100,AMD 3100,AMD-3329

Virus Protease; HIV Protease; CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Plerixafor (AMD-3329) 是一种趋化因子受体拮抗剂,可阻断基质细胞衍生因子与细胞受体 CXCR4 的结合。它也是 CXCR7 的变构激动剂,是免疫刺激剂和造血干细胞动员剂,还抑制HIV-1和HIV-2的复制,EC50为 1-10 nM。
T0029 Procaine

Duracaine,Spinocaine,普鲁卡因,Novocaine,Vitamin H3,奴夫卡因

Histone Demethylase; DNA/RNA Synthesis; Sodium Channel Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Membrane transporter/Ion channel
Procaine (Vitamin H3) 是DNA 脱甲基剂,是一种酯类局部麻醉剂。它起效缓慢,作用持续时间短,主要用于浸润麻醉、周围神经阻滞和脊髓阻滞。
TP1540 Jagged-1 (188-204)

Jagged-1 188-204

Gamma-secretase Neuroscience; Proteases/Proteasome; Stem Cells
Jagged-1 (188-204) 是 JAG-1 蛋白的一个片段。其中 JAG-1 能够诱导单核细胞衍生的人树突状细胞成熟,是一种在培养的和原发性多发性骨髓瘤细胞中高度表达的 Notch 配体。
T4134L OTS514

OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514

Apoptosis; TOPK Apoptosis; MAPK
OTS514 (OTS514 Hydrochloride) 是一种高效的 TOPK 抑制剂,IC50为 2.6 nM。它强效抑制 TOPK 阳性的肿瘤细胞生长,还可诱导细胞周期停滞和凋亡。
T11141 E64FC26

Others Others
E64FC26 是一种有效的蛋白质二硫键异构酶 (PDI) 家族泛抑制剂,具有抗肿瘤活性,抑制 PDIA1、PDIA3、PDIA4、TXNDC5 和 PDIA6,可用于研究多发性骨髓瘤和胰腺癌。
T14918 CDK9-IN-2

N2'-(反式-4-氨基环己基)-5'-氯-N6-[(3-氟苯基)甲基]-[2,4'-联吡啶]-2',6-二胺

Others; CDK Cell Cycle/Checkpoint; Others
CDK9-IN-2 是一种特异性CDK9抑制剂。它在 A2058 皮肤细胞系(72 小时)和 H929 多发性骨髓瘤细胞系(72小时)的IC50分别为 7 nM 和 5 nM。
T16280 Nedocromil

FPL 59002,尼多克罗

Leukotriene Receptor; Prostaglandin Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Nedocromil (FPL 59002) 对多种介质的作用或形成有抑制作用,包括组胺,前列腺素 D2和白三烯 C4。
T19533 Pyraclonil

Others Others
Pyraclonil, a herbicide agent, effectively controls susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations as it acts as a proporphyrinogen oxidase (PPO) inhibitor.

化合物

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA)
Cat.No: T22774L
Synonym:
Target: Others
Epigenetic Multiple Ligand
Cat.No: T72013
Synonym:
Target:
ferritin heavy chain fragment [Multiple species]
Cat.No: TP2248
Synonym:
Target: Others
MAP kinase fragment [Multiple species]
Cat.No: TP2269
Synonym:
Target: Others
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]
Cat.No: T22774
Synonym:
Target: Others
CCF642
Cat.No: T6800
Synonym: AC1LYELL
Target: Others
Elevenostat
Cat.No: T9745
Synonym:
Target: HDAC
glatiramer Acetate
Cat.No: TP2315
Synonym:
Target: Others
BMS-P5
Cat.No: T22277
Synonym:
Target: PAD
Voruciclib
Cat.No: T10096L
Synonym:
Target: CDK
GSK467
Cat.No: T5484
Synonym:
Target: Histone Demethylase, Histone Methyltransferase
CASIN
Cat.No: T3971
Synonym: Pirl1-related Compound 2
Target: CDK, STAT, Ras
dCBP-1
Cat.No: T9370
Synonym:
Target: Epigenetic Reader Domain, Ligand for E3 Ligase
CB-5083
Cat.No: T6796
Synonym: CB5083,CB 5083
Target: p97
SRI-011381
Cat.No: T4283
Synonym:
Target: TGF-beta/Smad
Lenalidomide hemihydrate
Cat.No: T22922
Synonym:
Target: TNF, Ligand for E3 Ligase, Molecular Glues
GSK3685032
Cat.No: T9573
Synonym:
Target: DNA Methyltransferase
BMS-P5 free base
Cat.No: T22277L
Synonym:
Target: PAD
MST-312
Cat.No: T41290
Synonym: Telomerase Inhibitor IX
Target: Telomerase
Procaine hydrochloride
Cat.No: T0802
Synonym: Novocaine HCl,Procaine HCl,盐酸普鲁卡因
Target: Histone Demethylase, 5-HT Receptor, DNA/RNA Synthesis, Sodium Channel, NMDAR, AChR
Talmapimod
Cat.No: T12871
Synonym: 他匹莫德,SCIO-469
Target: p38 MAPK
S1p receptor agonist 1
Cat.No: T4031
Synonym: S1p-receptor-agonist-1
Target: S1P Receptor, LPL Receptor
ZK824190
Cat.No: T13408
Synonym:
Target: Others, Serine Protease
BRD9876
Cat.No: T8342
Synonym: 6-叔丁基-2,3-二氰基萘
Target: Others, Kinesin, Microtubule Associated
Citarinostat
Cat.No: T3661
Synonym: ACY241,HDAC-IN-2
Target: HDAC
Siponimod
Cat.No: T6403
Synonym: 辛波莫德,BAF-312
Target: S1P Receptor, LPL Receptor
Tolebrutinib
Cat.No: T9125
Synonym: PRN2246,SAR442168
Target: BTK
Nelfinavir
Cat.No: T7779
Synonym: AG1341,甲磺酸萘非那韦
Target: HIV Protease
SC99
Cat.No: T8719
Synonym:
Target: Apoptosis, JAK, STAT
R547
Cat.No: T6312
Synonym: Ro 4584820
Target: Apoptosis, GSK-3, PKA, CDK
Laquinimod
Cat.No: T6561
Synonym: LAQ,ABR-215062,拉喹莫德
Target: Apoptosis, Others, NF-κB
Iberdomide
Cat.No: T7791
Synonym: CC-220
Target: Apoptosis, Ligand for E3 Ligase
Lenalidomide
Cat.No: T1642
Synonym: 来那度胺,CC-5013
Target: Apoptosis, TNF, Ligand for E3 Ligase, Molecular Glues
Ozanimod
Cat.No: T6923
Synonym: 奥扎莫德,RPC-1063
Target: S1P Receptor, LPL Receptor
AVN-944
Cat.No: T1979
Synonym: VX-944
Target: Dehydrogenase
OTS514 hydrochloride
Cat.No: T4134
Synonym: OTS-514 hydrochloride,OTS514 hydrochloride(1338540-63-8(free base))
Target: Apoptosis, TOPK
Nelfinavir Mesylate
Cat.No: T6001
Synonym: Viracept,Nelfin,AG1343,AG 1343 Mesylate,甲磺酸奈非那韦
Target: HIV Protease
SRI-011381 hydrochloride
Cat.No: T5129
Synonym: SRI-011381 hydrochloride [1629138-41-5(free base)]
Target: TGF-beta/Smad
(E/Z)-Zotiraciclib
Cat.No: T21503
Synonym: (E/Z)-TG02,(E/Z)-SB1317
Target: FLT, JAK, CDK
NVP-ADW742
Cat.No: T6079
Synonym: ADW742,ADW,GSK 552602A
Target: Apoptosis, IGF-1R
Cladribine
Cat.No: T2558
Synonym: 2-chlorodeoxyadenosine,克拉屈滨,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA
Target: Apoptosis, Adenosine deaminase
Alisertib
Cat.No: T2241
Synonym: MLN 8237,4-[[9-氯-7-(2-氟-6-甲氧基苯基)-5H-嘧啶并[5,4-D][2]苯并氮杂卓-2-基]氨基]-2-甲氧基苯甲酸
Target: Apoptosis, Aurora Kinase, Autophagy
Plerixafor
Cat.No: T1776
Synonym: 普乐沙福,JM3100,AMD 3100,AMD-3329
Target: Virus Protease, HIV Protease, CXCR
Procaine
Cat.No: T0029
Synonym: Duracaine,Spinocaine,普鲁卡因,Novocaine,Vitamin H3,奴夫卡因
Target: Histone Demethylase, DNA/RNA Synthesis, Sodium Channel
Jagged-1 (188-204)
Cat.No: TP1540
Synonym: Jagged-1 188-204
Target: Gamma-secretase
OTS514
Cat.No: T4134L
Synonym: OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514
Target: Apoptosis, TOPK
E64FC26
Cat.No: T11141
Synonym:
Target: Others
CDK9-IN-2
Cat.No: T14918
Synonym: N2'-(反式-4-氨基环己基)-5'-氯-N6-[(3-氟苯基)甲基]-[2,4'-联吡啶]-2',6-二胺
Target: Others, CDK
Nedocromil
Cat.No: T16280
Synonym: FPL 59002,尼多克罗
Target: Leukotriene Receptor, Prostaglandin Receptor, Histamine Receptor
Pyraclonil
Cat.No: T19533
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T4903 Heptadecanoic acid

Others; Endogenous Metabolite Metabolism; Others
Heptadecanoic acid 是奇链饱和脂肪酸,与一些疾病(如冠心病、糖尿病前期和 2 型糖尿病以及多发性硬化症)有关。
T2844 Hyperoside

Quercetin 3-galactoside,金丝桃甙,金丝桃苷,Hyperin

Others; Influenza Virus; Antifungal Microbiology/Virology; Others
Hyperoside (Hyperin) 是一种从Camptotheca acuminate 提取的黄酮,具有多种生物活性,如心肌保护、抗氧化还原和抗炎活性。
T13768 (+)-Medicarpin

Estrogen/progestogen Receptor Endocrinology/Hormones
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It exhibits potent inhibition of osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, which is mediated by the estrogen receptor (ER) β.
T17048 Tetradecanoylcarnitine

L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine

Endogenous Metabolite Metabolism
Tetradecanoylcarnitine (L-Myristoylcarnitine) 是一种酰基肉碱,参与长链脂肪酸的β-氧化,是极长链酰辅酶A脱氢酶缺乏症的一种潜在标记物。
T3002 Piperine

胡椒碱,1-Piperoylpiperidine,Bioperine

P450; Endogenous Metabolite; P-gp; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience
Piperine (Bioperine) 是从胡椒中分离的一种生物碱,可以抑制P-糖蛋白和 CYP3A4 的活性,在HeLa 细胞中的IC50值为61.94±0.054 μg/mL。它已用于研究治疗多发性骨髓瘤和吞咽障碍的试验。
T4784 (S)-(-)-Phenylethanol

(S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol

Others; Endogenous Metabolite Metabolism; Others
(S)-(-)-Phenylethanol ((-)-Methyl phenyl carbinol) 是内源性代谢产物的一种。
T5239 Cholesteryl sulfate sodium

Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate

Endogenous Metabolite; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) 是内源性代谢产物的一种。
T5S1026 Apigenin-7-glucuronide

Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸

MMP Proteases/Proteasome
Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) 能够抑制基质金属蛋白酶的活性,其对 MMP-3 (IC50:12.87 μM),MMP-8 (IC50:22.39 μM),MMP-9 (IC50:17.52 μM),MMP-13 (IC50:0.27 μM)。
T4808 Agmatine sulfate

Agmatine sulfate salt,硫酸胍基丁胺

Endogenous Metabolite; NO Synthase; Imidazoline Receptor Immunology/Inflammation; Metabolism; Neuroscience
Agmatine sulfate (Agmatine sulfate salt) 是咪唑啉受体的内源性激动剂和一氧化氮合酶抑制剂。它靶向神经递质系统,离子通道和一氧化氮合成。
T1166 Ellipticine

玫瑰树碱,NSC 71795,Elliptisine

Topoisomerase DNA Damage/DNA Repair
Ellipticine (Elliptisine) 是一种有效的抗肿瘤剂,抑制 DNA 拓扑异构酶 II 活性,对白血病、神经母细胞瘤和胶质母细胞瘤有部分活性。
T5273 2-Hydroxy-3-methylbutanoic acid

2-Hydroxy-3-methylbutyric acid,2-Hydroxyisovaleric Acid,2-羟基-3-甲基丁酸,(±)-2-Hydroxyisopentanoic Acid

Others; Endogenous Metabolite Metabolism; Others
2-Hydroxy-3-methylbutanoic acid ((±)-2-Hydroxyisopentanoic Acid) 是一种 GHB 的结构类似物,其中GHB 是一种中枢神经系统中发现的天然物质,也是一种神经药物。
T5530 Mithramycin A

Plicamycin

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Mithramycin A (Plicamycin) 是一种dna 结合的抗肿瘤抗生素,选择性特异性蛋白1 (Sp1)抑制剂,通过降低Sp1蛋白抑制多种肿瘤的生长。特异性蛋白1 (Sp1)是一种锌指转录因子,调节多种细胞功能,促进肿瘤进展。
T3752 4-Hydroxybenzyl alcohol

4-Methylolphenol,P-Methylolphenol,对羟基苯甲醇

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
4-Hydroxybenzyl alcohol (P-Methylolphenol) 是广泛分布于各种植物中的一种酚类天然产物,具有抗炎、抗氧化和抗伤害感受活性。它抑制肿瘤血管生成和生长,有神经保护作用。
T3398 Icaritin

Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin

Apoptosis; JAK; STAT; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
Icaritin (Anhydroicaritin) 是Epimedium Genusis 的异戊二烯类黄酮衍生物,有效抑制 K562 细胞和原代 CML 细胞的增殖。它可以调节MAPK/ERK/JNK 和JAK2/STAT3/AKT 信号传导,并具有增强成骨的作用。
T4798 N-Acetyl-L-leucine

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-leucine 是内源性代谢产物的一种。
T4S1469 Cucurbitacin IIb

葫芦素IIB,雪胆素乙

Apoptosis; Others Apoptosis; Others
Cucurbitacin IIb 是一种雪胆中的活性成分。它阻碍 STAT3,JNK 和 Erk1/2 的磷酸化,提高 IκB 和 NF-κB (p65) 的磷酸化水平,抑制 NF-κB (p65) 的核转位,降低 IκBα 和 TNF-α 的 mRNA 水平。它能够诱导细胞凋亡,具有抗炎作用。
T3851 Vicenin 2

Vicenin -2,维采宁 2,新西兰牡荆苷

RAAS Endocrinology/Hormones
Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂,IC50=43.83 μM。
T4855 Tricosanoic acid

Tricosan-1-oic acid,二十三烷酸

Endogenous Metabolite Metabolism
Tricosanoic acid (Tricosan-1-oic acid) 是毛发生长激活剂,是长链脂肪酸。
T4837 Itaconic acid

methylene-butanedioicaci,衣康酸

Others; Endogenous Metabolite Metabolism; Others
Itaconic acid (methylene-butanedioicaci) 是聚合物,化学物质和燃料的合成前体。Itaconic acid 可由真菌合成。它也是巨噬细胞特异性代谢产物。它介导巨噬细胞代谢和腹膜肿瘤之间的串扰。
T4707 3-Hydroxyanthranilic acid

3-HYDROXY-2-AMINOBENZOIC ACID,3-羟基-2-氨基苯甲酸

Others; Endogenous Metabolite Metabolism; Others
3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID) 是犬尿氨酸途径中的色氨酸代谢物。它已在人类表皮和膀胱组织中发现,并且在多种生物体液中也已检测到,例如尿液和血液。在细胞内,它主要位于细胞质中。 它存在于从酵母到人类的所有真核生物中。
T19504 Paullinic acid

Others Others
Paullinic acid is a long-chain fatty acid that has been detected in multiple biofluids.
T12403 Penitrem A

Others Others
Penitrem A is a selective antagonist of BK channel with antiproliferative and anti-invasive activities against multiple malignancies.
T31911 Ganodermic acid S

Ganoderic acid R

Ganodermic acid S, as a membrane acting agent isolated from the fungus Ganoderma lucidum, exerts multiple effects on human platelet function.
TN4732 Pachysamine M

Others Others
Pachysamine M shows inhibitory activities against multiple types of cancer cells.
TN1973 Naringenin triacetate

三乙酸柚皮素酯

Others Others
Naringenin triacetate exhibits a better binding affinity with multiple crystal structures of first bromodomain BRD4 (BRD4 BD1) when compared with the known inhibitors.
TN5369 Dehydroleucodine

Dehydroleucodin

Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating adipocyte differentiation by modulat
T74200 Glicophenone

Glicophenone 作为一种抗细菌(antibacterial)剂,对MRSA OM481、MRSA OM505、MRSA OM584、MRSA OM623 以及MSSA 209P的MIC值均为32 μg/mL。
T82070 Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate

Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate是一种高度功能化的双环石萜类化合物,源自Euphorbia officinarum的乳胶。
T78539 (+)-Coclaurine hydrochloride

d-Coclaurine hydrochloride,(R)-Coclaurine hydrochloride,(+)-(R)-Coclaurine hydrochloride

Others Others
(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride 是从多种植物中分离得到的四氢异喹啉类生物碱,具有抗衰老活性。
T11202 Enniatin complex

Others Others
Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it has demonstrated the ability to induce apoptosis in multiple cancer cell lines. In addition to these activities, the Enniatin complex possesses ionophoric, antibiotic, and in vitro hypolipidemic properties.
TN4016 Ethyl 2,4,6-trihydroxybenzoate

Liver X Receptor Metabolism
Ethyl 2,4,6-trihydroxybenzoate is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells. It suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes.
TN3627 Chalepensin

ATPase; NADPH-oxidase; P450; Antifection Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepensin shows antiprotozoal activity; it also can cause significant inhibition of radicle growth of A. hypochondriacus and E. crus-galli.
TN5129 Tetrahydro tanshinone I

Others Others
Tetrahydro tanshinone I is one compound of Fufang Danshen Prescription (FDP) , liposome equilibrium dialysis system could simply and effectively esti-mate the absorption of multiple components in FDP in vivo, and predicts the potential bioactivity of thes
T73925 α-D-Glucose-1-phosphate disodium hydrate

α-D-Glucose-1-phosphate disodium hydrate 为合成葡萄糖醛酸的初始原料之一,同时,在心脏病研究领域,亦被广泛应用作为细胞抑制剂、抗生素、免疫抑制剂与循环系统研究的关键材料。
T77242 Pectin

Pectin是从高等植物细胞壁中提取的一种杂多糖。作为纳米颗粒制备,它用作活性分子的运载载体。此外,Pectin还具有吸附剂和广谱抗菌剂的功能,能够结合肠道粘膜中的细菌毒素及其他刺激物,从而缓解受刺激的黏膜。
T70495 Scytonemin

Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive one to scytonemin. Scytonemin , representing a novel Plk1 inhibitor, ...
T78506 α-Lactose hydrate

α-D-Lactose hydrate

α-Lactose (hydrate)(α-D-Lactose (hydrate))是哺乳动物乳汁的主要碳水化合物,由葡萄糖和半乳糖构成,并有α和β两种异构体。它广泛应用于食品和制药行业,常作为松散剂或凝聚剂,也用于稀释色素、香料或酶。
TN5280 (-)-Zeylenol

Zeylenol

Apoptosis Apoptosis
(-)-Zeylenol (Zeylenol) 是一种从 Uvaria grandiflora 的茎中提取的天然产物,具有抗炎、拒食和抗肿瘤生物活性,通过抑制多种炎症介质的合成或释放发挥作用。 zezelenol 对油菜根系生长有抑制作用,具有诱导人乳腺癌 MDA-MB231细胞凋亡的潜力。
TN4838 Pseurotin A

Antifection Microbiology/Virology
Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteria Erwinia carotovora and Pseudomonas syringae, with IC50 values of 220 and 112 microg ml(-1), r
TN1694 Gliotoxin

Apoptosis; NF-κB; Wnt/beta-catenin; COX; PKA; Antibacterial; Antifection Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
Gliotoxin 是一种次生代谢产物,由A. fumigatus 分泌,可以抑制巨噬细胞的吞噬作用和其他免疫细胞的免疫功能。它通过阻止 IκB 降解来抑制诱导型NF-κB 活性,从而诱导宿主细胞凋亡。它可以激活PKA 并增加细胞内 cAMP 浓度,调节肌动蛋白细胞骨架重排以促进A. fumigatus 内化到肺上皮细胞。
TN4286 Isodunnianol

NOS; NF-κB; ROS; AChR Immunology/Inflammation; Neuroscience; NF-κB
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. Isodunnianol, dunnianol, and Macrant
T83916 Cytogenin

Cytogenin(一种源自S. eurocidicum的香豆素衍生物)具有多种生物活性。在每日给药25 mg/kg剂量下,能减轻Ehrlich鼠自发性腺癌模型的肿瘤重量。在体内,Cytogenin(每日30和100 mg/kg)可减少链脲佐菌素诱导的体重下降和血浆葡萄糖水平上升,以及小鼠糖尿病模型中巨噬细胞胰腺浸润。同时,在每日100 mg/kg的剂量下,能降低小鼠巨噬细胞中zymosan和LPS诱导的一氧化氮产生,及LPS诱导的Il-6水平增加。
T38179 C16 3'-sulfo Galactosylceramide (d18:1/16:0)

C16 3'-sulfo Galactosylceramide (d18:1/16:0)

Others Others
C16 3'-sulfo Galactosylceramide (d18:1/16:0)是硫酸盐类糖脂的一种。C16 3'-sulfo Galactosylceramide (d18:1/16:0)是在猪脑和血浆中发现的一种比较丰富的硫化物,在小鼠的整个发育过程中会有所减少。C16 3'-sulfo Galactosylceramide (d18:1/16:0)在体外可抑制视网膜神经节细胞生长。C16 3'-sulfo Galactosylceramide (d18:1/16:0)已被用作量化大鼠小脑和多发性硬化症患者分离的白质中的硫化物的参照物。
T36915 21-Deoxycortisol

21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies. 1.Fiet, J., Villette, J.-M., Galons, H., et al.The application of a new highly-sensitive...

天然产物

Heptadecanoic acid
Cat.No: T4903
Synonym:
Target: Others, Endogenous Metabolite
Hyperoside
Cat.No: T2844
Synonym: Quercetin 3-galactoside,金丝桃甙,金丝桃苷,Hyperin
Target: Others, Influenza Virus, Antifungal
(+)-Medicarpin
Cat.No: T13768
Synonym:
Target: Estrogen/progestogen Receptor
Tetradecanoylcarnitine
Cat.No: T17048
Synonym: L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine
Target: Endogenous Metabolite
Piperine
Cat.No: T3002
Synonym: 胡椒碱,1-Piperoylpiperidine,Bioperine
Target: P450, Endogenous Metabolite, P-gp, Autophagy
(S)-(-)-Phenylethanol
Cat.No: T4784
Synonym: (S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol
Target: Others, Endogenous Metabolite
Cholesteryl sulfate sodium
Cat.No: T5239
Synonym: Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate
Target: Endogenous Metabolite, PKC
Apigenin-7-glucuronide
Cat.No: T5S1026
Synonym: Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸
Target: MMP
Agmatine sulfate
Cat.No: T4808
Synonym: Agmatine sulfate salt,硫酸胍基丁胺
Target: Endogenous Metabolite, NO Synthase, Imidazoline Receptor
Ellipticine
Cat.No: T1166
Synonym: 玫瑰树碱,NSC 71795,Elliptisine
Target: Topoisomerase
2-Hydroxy-3-methylbutanoic acid
Cat.No: T5273
Synonym: 2-Hydroxy-3-methylbutyric acid,2-Hydroxyisovaleric Acid,2-羟基-3-甲基丁酸,(±)-2-Hydroxyisopentanoic Acid
Target: Others, Endogenous Metabolite
Mithramycin A
Cat.No: T5530
Synonym: Plicamycin
Target: DNA/RNA Synthesis
4-Hydroxybenzyl alcohol
Cat.No: T3752
Synonym: 4-Methylolphenol,P-Methylolphenol,对羟基苯甲醇
Target: Apoptosis, Endogenous Metabolite
Icaritin
Cat.No: T3398
Synonym: Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin
Target: Apoptosis, JAK, STAT, Autophagy
N-Acetyl-L-leucine
Cat.No: T4798
Synonym:
Target: Others, Endogenous Metabolite
Cucurbitacin IIb
Cat.No: T4S1469
Synonym: 葫芦素IIB,雪胆素乙
Target: Apoptosis, Others
Vicenin 2
Cat.No: T3851
Synonym: Vicenin -2,维采宁 2,新西兰牡荆苷
Target: RAAS
Tricosanoic acid
Cat.No: T4855
Synonym: Tricosan-1-oic acid,二十三烷酸
Target: Endogenous Metabolite
Itaconic acid
Cat.No: T4837
Synonym: methylene-butanedioicaci,衣康酸
Target: Others, Endogenous Metabolite
3-Hydroxyanthranilic acid
Cat.No: T4707
Synonym: 3-HYDROXY-2-AMINOBENZOIC ACID,3-羟基-2-氨基苯甲酸
Target: Others, Endogenous Metabolite
Paullinic acid
Cat.No: T19504
Synonym:
Target: Others
Penitrem A
Cat.No: T12403
Synonym:
Target: Others
Ganodermic acid S
Cat.No: T31911
Synonym: Ganoderic acid R
Target:
Pachysamine M
Cat.No: TN4732
Synonym:
Target: Others
Naringenin triacetate
Cat.No: TN1973
Synonym: 三乙酸柚皮素酯
Target: Others
Dehydroleucodine
Cat.No: TN5369
Synonym: Dehydroleucodin
Target:
Glicophenone
Cat.No: T74200
Synonym:
Target:
Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate
Cat.No: T82070
Synonym:
Target:
(+)-Coclaurine hydrochloride
Cat.No: T78539
Synonym: d-Coclaurine hydrochloride,(R)-Coclaurine hydrochloride,(+)-(R)-Coclaurine hydrochloride
Target: Others
Enniatin complex
Cat.No: T11202
Synonym:
Target: Others
Ethyl 2,4,6-trihydroxybenzoate
Cat.No: TN4016
Synonym:
Target: Liver X Receptor
Chalepensin
Cat.No: TN3627
Synonym:
Target: ATPase, NADPH-oxidase, P450, Antifection
Tetrahydro tanshinone I
Cat.No: TN5129
Synonym:
Target: Others
α-D-Glucose-1-phosphate disodium hydrate
Cat.No: T73925
Synonym:
Target:
Pectin
Cat.No: T77242
Synonym:
Target:
Scytonemin
Cat.No: T70495
Synonym:
Target:
α-Lactose hydrate
Cat.No: T78506
Synonym: α-D-Lactose hydrate
Target:
(-)-Zeylenol
Cat.No: TN5280
Synonym: Zeylenol
Target: Apoptosis
Pseurotin A
Cat.No: TN4838
Synonym:
Target: Antifection
Gliotoxin
Cat.No: TN1694
Synonym:
Target: Apoptosis, NF-κB, Wnt/beta-catenin, COX, PKA, Antibacterial, Antifection
Isodunnianol
Cat.No: TN4286
Synonym:
Target: NOS, NF-κB, ROS, AChR
Cytogenin
Cat.No: T83916
Synonym:
Target:
C16 3'-sulfo Galactosylceramide (d18:1/16:0)
Cat.No: T38179
Synonym: C16 3'-sulfo Galactosylceramide (d18:1/16:0)
Target: Others
21-Deoxycortisol
Cat.No: T36915
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-05162 MEGF10 Protein, Human, Recombinant (hFc)

EMARDD,multiple EGF-like-domains 10

Human HEK293
MEGF10 (Multiple EGF Like Domains 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility, and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. MEGF10 may also function in the mosaic spacing of specific neuron subtypes in the retina t...
TMPY-02178 EGFL7 Protein, Mouse, Recombinant (His)

Zneu1,VE-statin,EGF-like-domain, multiple 7

Mouse Baculovirus-Insect Cells
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains protein 7, Vascular endothelial statin, NOTCH4-like protein and EGFL7, is a secreted protein which contains twoEGF-like domains and oneEMI domain. EGFL7 was identified by a number of groups as a putative secreted factor produced by the vascular endothelial cells (ECs). EGFL7 is described as a novel endothelial cell-derived factor invo...
TMPY-04301 MEGF10 Protein, Human, Recombinant (His)

EMARDD,multiple EGF-like-domains 10

Human HEK293
MEGF10 (Multiple EGF Like Domains 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility, and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. MEGF10 may also function in the mosaic spacing of specific neuron subtypes in the retina t...
TMPY-04647 EGFL6 Protein, Human, Recombinant (His & FLAG)

EGF-like-domain, multiple 6,MAEG,W80

Human Baculovirus-Insect Cells
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-...
TMPY-03780 EGFL6 Protein, Human, Recombinant (His)

W80,EGF-like-domain, multiple 6,MAEG

Human Baculovirus-Insect Cells
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-...
TMPY-00078 EGFL6 Protein, Mouse, Recombinant (His)

Egfl6,MGC141463,Maeg,EGF-like-domain, multiple 6

Mouse HEK293
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-...
TMPY-00094 EGFL6 Protein, Mouse, Recombinant (hFc)

EGF-like-domain, multiple 6,MGC141463,Egfl6,Maeg

Mouse HEK293
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-...
TMPY-04339 EGFL7 Protein, Human, Recombinant (His)

VE-STATIN,NEU1,EGF-like-domain, multiple 7,ZNEU1

Human Baculovirus-Insect Cells
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains protein 7, Vascular endothelial statin, NOTCH4-like protein and EGFL7, is a secreted protein which contains twoEGF-like domains and oneEMI domain. EGFL7 was identified by a number of groups as a putative secreted factor produced by the vascular endothelial cells (ECs). EGFL7 is described as a novel endothelial cell-derived factor invo...
TMPH-00075 At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)

Multiple inositol polyphosphate phosphatase 1,2,3-b...

Arabidopsis thaliana E. coli
TMPH-00076 At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)

2,3-bisphosphoglycerate 3-phosphatase,Multiple inos...

Arabidopsis thaliana Baculovirus
TMPH-01168 CDKN2B Protein, Human, Recombinant (His & Myc)

Multiple tumor suppressor 2,Cyclin-dependent kinase...

Human E. coli
CDKN2B Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPJ-01390 MINPP1 Protein, Human, Recombinant (His)

3,4,5)-Tetrakisphosphate 3-Phosphatase,2,5)P(4) 3-Phosphatas...

Human Human Cells
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and re...
TMPK-01151 MXRA8 Protein, Human, Recombinant (His)

Asp3,Limitrin,Adipocyte-specific 3,DICAM,Adipocyte-specific ...

Human HEK293
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses.
TMPY-04333 LRRC15 Protein, Human, Recombinant (hFc)

leucine rich repeat containing 15,LIB

Human HEK293
LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmembrane protein demonstrated to play important roles in cancer. LRRC15 is highly expressed in multiple solid tumor indications with limited normal tissue expression. It was expressed on stromal fibroblasts in many solid tumors (e.g., breast, head, and neck, lung, pancreatic) as well...
TMPY-01601 AXL Protein, Human, Recombinant (His)

UFO,ARK,JTK11,AXL receptor tyrosine kinase,Tyro7

Human HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multiple cell types. Axl functions in dampening the immune response, regulating cytokine secretion, clearing apoptotic cells and debris, and maintaining cell survival. Axl is upregulated in various disease states, such as in the cuprizone toxicity-induced model of demyelination and in ...
TMPK-00347 Serum Albumin Protein, Human, Recombinant (His & Avi)

Serum albumin,PRO0903,Albumin,PRO1341,ALB,ANALBA,FDAH,PRO088...

Human HEK293
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier.
TMPY-02886 IL-17A Protein, Human, Recombinant

IL-17,白细胞介素,interleukin 17A,CTLA8,白介素,IL17,IL-17A,CTLA-8

Human E. coli
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocyt...
TMPY-02900 IL-17A Protein, Mouse, Recombinant

IL-17A,Ctla8,Ctla-8,interleukin 17A,Il17,白介素,白细胞介素,IL-17

Mouse E. coli
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocyt...
TMPJ-01405 Kallikrein 5/KLK5 Protein, Human, Recombinant (His)

Stratum Corneum Tryptic Enzyme,Kallikrein-Like Protein 2,KLK...

Human Human Cells
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in mul...
TMPY-01803 FOLR1 Protein, Mouse, Recombinant (His)

folate receptor 1 (adult),Folbp1,FBP1,Folbp-1

Mouse HEK293
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, mul...
TMPY-04778 Prolactin Protein, Human, Recombinant (His)

prolactin

Human Baculovirus-Insect Cells
Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial cells (astrocytes, microglia and oligodendrocytes) of the brain. It is generally believed that in vertebrates, prolactin (PRL) is predominantly synthesized and released by pituitary lactotrophs and plays important roles in many physiological processes via activation of PRL recep...
TMPY-01815 FOLR1 Protein, Human, Recombinant (His)

FBP,Folate Binding Protein,folate receptor 1 (adult),FOLR

Human HEK293
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, mul...
TMPY-06022 FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)

folate receptor 1 (adult)

Cynomolgus,Rhesus HEK293
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, mul...
TMPY-02424 Prolactin Protein, Mouse, Recombinant (His)

AV290867,Prl1a1,prolactin

Mouse Baculovirus-Insect Cells
Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial cells (astrocytes, microglia and oligodendrocytes) of the brain. It is generally believed that in vertebrates, prolactin (PRL) is predominantly synthesized and released by pituitary lactotrophs and plays important roles in many physiological processes via activation of PRL recep...
TMPY-01906 SEMA4D Protein, Human, Recombinant (His)

CD100,COLL4,C9orf164,semaphorin 4D,SEMAJ,coll-4,M-sema-G

Human HEK293
Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody pro...
TMPY-02333 ULBP-2 Protein, Human, Recombinant (His)

ALCAN-α,UNQ463 / PRO791,NKG2DL2,ALCAN-alpha,UL16 binding pro...

Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cy...
TMPY-00756 FGF-1 Protein, Human, Recombinant

AFGF,ECGF-beta,ECGFB,fibroblast growth factor 1 (acidic),GLI...

Human E. coli
aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein ...
TMPY-03284 IL-T4 Protein, Human, Recombinant (His)

ILT-4,MIR-10,leukocyte immunoglobulin like receptor B2,LIR-2...

Human HEK293
ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecul...
TMPY-00831 IFN-beta Protein, Human, Recombinant (hFc)

IFNB,IFN-β,Interferon beta,interferon, beta 1, fibroblast,In...

Human HEK293
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relaps...
TMPY-05592 ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated

ALCAN-α,NKG2DL2,RAET1H,UL16 binding protein 2,N2DL2,ALCAN-al...

Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cy...
TMPY-03467 IFN-beta Protein, Mouse, Recombinant

Ifb,IFN-β,interferon, beta 1, fibroblast,干扰素,IFNB,IFN-beta,i...

Mouse HEK293
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relaps...
TMPY-03145 IFN-beta Protein, Human, Recombinant

IFN-β,interferon, β1, fibroblast,IFNB,IFB,IFF,Interferon β,I...

Human CHO
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites, and tumor cells. Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relaps...
TMPJ-00059 IL-7 Protein, Human, Recombinant (His)

Interleukin-7,IL7,白细胞介素,IL-7,白介素

Human Human Cells
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-spe...
TMPY-01009 TGFBI Protein, Human, Recombinant (His)

CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be...

Human HEK293
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys...
TMPY-05227 TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated

TIMD3,hepatitis A virus cellular receptor 2,CD366,KIM-3,TIMD...

Human HEK293
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specifically identifies Th1 cells in both the mouse and human. Recently, the identification of Galectin-9 as a ligand for TIM-3 has established the TIM-3-Galectin-9 pathway as an important regulator of Th1 immunity and toleranc...
TMPY-01621 TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)

TIMD-3,hepatitis A virus cellular receptor 2,HAVcr-2,Tim-3,T...

Human HEK293
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specifically identifies Th1 cells in both the mouse and human. Recently, the identification of Galectin-9 as a ligand for TIM-3 has established the TIM-3-Galectin-9 pathway as an important regulator of Th1 immunity and toleranc...
TMPY-00586 CLEC-2 Protein, Mouse, Recombinant (hFc)

1810061I13Rik,Clec2,C-type lectin domain family 1, member B,...

Mouse HEK293
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and...
TMPY-05842 IL-11 Protein, Cynomolgus, Recombinant

interleukin 11

Cynomolgus E. coli
IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell prolifer...
TMPY-02929 ENTPD2 Protein, Human, Recombinant (aa 29-460, His)

ectonucleoside triphosphate diphosphohydrolase 2,NTPDase-2,R...

Human Baculovirus-Insect Cells
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in...
TMPY-00635 IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)

IL7R α/CD127,interleukin 7 receptor

Cynomolgus HEK293
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alpha (CD127) signaling is essential for T-cell development and regulation of naive and memory T-cell homeostasis. IL-7RA is critically required for the proper development and function of lymphoid cells. Therefore, the IL-7RA is critically required for the proper development and fun...
TMPY-03488 IL-11 Protein, Human, Recombinant

白细胞介素,interleukin 11,IL-11,白介素,AGIF

Human E. coli
IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell prolifer...
TMPY-04178 IL-11 Protein, Mouse, Recombinant

IL-11,interleukin 11,白细胞介素,白介素

Mouse E. coli
IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell prolifer...
TMPY-01209 IL-7R alpha/CD127 Protein, Human, Recombinant (His)

IL7RA,ILRA,CD127,CDW127,IL-7R-α,IL-7R-alpha,IL-7R,IL7R α/CD1...

Human HEK293
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alpha (CD127) signaling is essential for T-cell development and regulation of naive and memory T-cell homeostasis. IL-7RA is critically required for the proper development and function of lymphoid cells. Therefore, the IL-7RA is critically required for the proper development and fun...
TMPY-05013 PSGL-1/CD162 Protein, Human, Recombinant (mFc)

PSGL-1,CLA,selectin P ligand,PSGL1,CD162

Human HEK293
P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and a...
TMPY-02286 Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His)

cholinergic receptor, muscarinic 1

H1N1 E. coli
The Influenza virus matrix protein 1 (M1) is a matrix protein of the influenza virus. M1 protein has been shown to play a crucial role in virus replication, assembly, and budding. It forms a coat inside the viral envelope. This is a bifunctional membrane/RNA-binding protein that mediates the encapsidation of RNA-nucleoprotein cores into the membrane envelope. M1 consists of two domains connected by a linker sequence. The N-terminal domain has a multi-helical structure. The C-terminal domain also...
TMPY-02881 RAGE Protein, Human, Recombinant

RAGE,advanced glycosylation end product-specific receptor

Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, an...
TMPY-05081 Notch 1 Protein, Human, Recombinant (hFc)

notch 1,TAN1,hN1,AOVD1,AOS5

Human HEK293
NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair the regeneration of skeletal muscles.NOTCH1 is a prevalent signaling pathway in T cell acute lymphoblastic leukemia (T-ALL). The NOTCH signaling pathway is a conserved signaling cascade that regulates many aspects of development and homeostasis in multiple organ systems. The pro...
TMPY-03531 PSGL-1/CD162 Protein, Human, Recombinant (His)

selectin P ligand,PSGL-1,PSGL1,CD162,CLA

Human HEK293
P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~12 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and a...
TMPY-04832 OX40L/TNFSF4 Protein, Human, Recombinant (hFc)

CD252,OX-40L,tumor necrosis factor (ligand) superfamily, mem...

Human HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX40. It is found to play a rol...
TMPY-02927 RAGE Protein, Human, Recombinant (His)

RAGE,advanced glycosylation end product-specific receptor

Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certain members of the S100/calgranulin family of proteins, high mobility group box 1 (HMGB1), advanced oxidation protein products, and amyloid (beta-sheet fibrils). Initial studies investigating the role of RAGE in renal dysfunction focused on diabetes, neurodegenerative disorders, an...
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重组蛋白

MEGF10 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05162
Species: Human
Expression System: HEK293
EGFL7 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02178
Species: Mouse
Expression System: Baculovirus-Insect Cells
MEGF10 Protein, Human, Recombinant (His)
Cat.No: TMPY-04301
Species: Human
Expression System: HEK293
EGFL6 Protein, Human, Recombinant (His & FLAG)
Cat.No: TMPY-04647
Species: Human
Expression System: Baculovirus-Insect Cells
EGFL6 Protein, Human, Recombinant (His)
Cat.No: TMPY-03780
Species: Human
Expression System: Baculovirus-Insect Cells
EGFL6 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00078
Species: Mouse
Expression System: HEK293
EGFL6 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00094
Species: Mouse
Expression System: HEK293
EGFL7 Protein, Human, Recombinant (His)
Cat.No: TMPY-04339
Species: Human
Expression System: Baculovirus-Insect Cells
At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)
Cat.No: TMPH-00075
Species: Arabidopsis thaliana
Expression System: E. coli
At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)
Cat.No: TMPH-00076
Species: Arabidopsis thaliana
Expression System: Baculovirus
CDKN2B Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01168
Species: Human
Expression System: E. coli
MINPP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01390
Species: Human
Expression System: Human Cells
MXRA8 Protein, Human, Recombinant (His)
Cat.No: TMPK-01151
Species: Human
Expression System: HEK293
LRRC15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04333
Species: Human
Expression System: HEK293
AXL Protein, Human, Recombinant (His)
Cat.No: TMPY-01601
Species: Human
Expression System: HEK293
Serum Albumin Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00347
Species: Human
Expression System: HEK293
IL-17A Protein, Human, Recombinant
Cat.No: TMPY-02886
Species: Human
Expression System: E. coli
IL-17A Protein, Mouse, Recombinant
Cat.No: TMPY-02900
Species: Mouse
Expression System: E. coli
Kallikrein 5/KLK5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01405
Species: Human
Expression System: Human Cells
FOLR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01803
Species: Mouse
Expression System: HEK293
Prolactin Protein, Human, Recombinant (His)
Cat.No: TMPY-04778
Species: Human
Expression System: Baculovirus-Insect Cells
FOLR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01815
Species: Human
Expression System: HEK293
FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-06022
Species: Cynomolgus,Rhesus
Expression System: HEK293
Prolactin Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02424
Species: Mouse
Expression System: Baculovirus-Insect Cells
SEMA4D Protein, Human, Recombinant (His)
Cat.No: TMPY-01906
Species: Human
Expression System: HEK293
ULBP-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02333
Species: Human
Expression System: HEK293
FGF-1 Protein, Human, Recombinant
Cat.No: TMPY-00756
Species: Human
Expression System: E. coli
IL-T4 Protein, Human, Recombinant (His)
Cat.No: TMPY-03284
Species: Human
Expression System: HEK293
IFN-beta Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00831
Species: Human
Expression System: HEK293
ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated
Cat.No: TMPY-05592
Species: Human
Expression System: HEK293
IFN-beta Protein, Mouse, Recombinant
Cat.No: TMPY-03467
Species: Mouse
Expression System: HEK293
IFN-beta Protein, Human, Recombinant
Cat.No: TMPY-03145
Species: Human
Expression System: CHO
IL-7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00059
Species: Human
Expression System: Human Cells
TGFBI Protein, Human, Recombinant (His)
Cat.No: TMPY-01009
Species: Human
Expression System: HEK293
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05227
Species: Human
Expression System: HEK293
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01621
Species: Human
Expression System: HEK293
CLEC-2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00586
Species: Mouse
Expression System: HEK293
IL-11 Protein, Cynomolgus, Recombinant
Cat.No: TMPY-05842
Species: Cynomolgus
Expression System: E. coli
ENTPD2 Protein, Human, Recombinant (aa 29-460, His)
Cat.No: TMPY-02929
Species: Human
Expression System: Baculovirus-Insect Cells
IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-00635
Species: Cynomolgus
Expression System: HEK293
IL-11 Protein, Human, Recombinant
Cat.No: TMPY-03488
Species: Human
Expression System: E. coli
IL-11 Protein, Mouse, Recombinant
Cat.No: TMPY-04178
Species: Mouse
Expression System: E. coli
IL-7R alpha/CD127 Protein, Human, Recombinant (His)
Cat.No: TMPY-01209
Species: Human
Expression System: HEK293
PSGL-1/CD162 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05013
Species: Human
Expression System: HEK293
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His)
Cat.No: TMPY-02286
Species: H1N1
Expression System: E. coli
RAGE Protein, Human, Recombinant
Cat.No: TMPY-02881
Species: Human
Expression System: HEK293
Notch 1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05081
Species: Human
Expression System: HEK293
PSGL-1/CD162 Protein, Human, Recombinant (His)
Cat.No: TMPY-03531
Species: Human
Expression System: HEK293
OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04832
Species: Human
Expression System: HEK293
RAGE Protein, Human, Recombinant (His)
Cat.No: TMPY-02927
Species: Human
Expression System: HEK293
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