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TargetMol产品目录中 "

b-4

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  • 抑制剂&激动剂
    552
    TargetMol | Inhibitors_Agonists
  • 化合物库
    1
    TargetMol | Compound_Libraries
  • 重组蛋白
    232
    TargetMol | Recombinant_Protein
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    22
    TargetMol | Peptide_Products
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    4
    TargetMol | Inhibitory_Antibodies
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    7
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    7
    TargetMol | PROTAC
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    150
    TargetMol | Natural_Products
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    7
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    134
    TargetMol | Antibody_Products
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    4
    TargetMol | Disease_Modeling_Products
  • Teleocidin B-4
    T8852211032-05-6
    Teleocidin B-4 作为一种PKC激活剂,能够通过 PKCα mTORC 信号通路增强HIF-1α蛋白的积累,并提升缺氧诱导因子 1 (HIF-1) 的活性,主要应用于癌症相关的研究领域。
    • 待询
    10-14周
    规格
    数量
  • Laxiflorin B-4
    T81947
    Laxiflorin B-4为改性Laxiflorin B,其对ERK1 2的亲和力更高,具备更强的抗肿瘤活性。
    • 待询
    规格
    数量
  • Adenine hydrochloride
    腺嘌呤盐酸盐, Adenine HCl, 6-Aminopurine hydrochloride
    T62252922-28-3
    Adenine hydrochloride (6-Aminopurine hydrochloride) 是一种嘌呤,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。
    • ¥ 125
    现货
    规格
    数量
  • Adenine
    腺嘌呤, Vitamin B4, 6-Aminopurine
    T006473-24-5
    Adenine (6-Aminopurine) 是一种嘌呤衍生物,是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用,作为 DNA 和 RNA 的化学成分。
    • ¥ 235
    现货
    规格
    数量
    TargetMol | Citations 客户已引用
  • Lipopolysaccharides, Escherichiacoli
    脂多糖 来源于大肠杆菌, Lipopolysaccharide, E. coli O111:B4
    T4107893572-42-0
    Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) 来源于大肠杆菌O111:B4, 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides, Escherichiacoli 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides, Escherichiacoli 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。
    • ¥ 475
    现货
    规格
    数量
    TargetMol | Citations 客户已引用
  • 12-oxo Leukotriene B4
    12-oxo Leukotriene B4
    T37256136696-10-1
    Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. 12-oxo LTB4 is an initial metabolite of LTB4 formed via the LTB4 12-hydroxydehydrogenase pathway. It is rapidly converted to 10,11-dihydro-12-oxo-LTB4, followed by reduction of the 12-oxo group to give 10,11-dihydro-LTB4. 12-oxo-LTB4 (EC50 = 33 nM) is about 70-fold less potent than LTB4 (EC50 = 0.46 nM) at stimulating Ca2+ mobilization in human neutrophils. It is also significantly less potent than LTB4 at stimulating neutrophil migration with EC50 values of 170 and 2.7 nM for 12-oxo-LTB4 and LTB4, respectively.
    • 待估
    35日内发货
    规格
    数量
  • Saikosaponin B4
    柴胡皂苷B4
    T821058558-09-1
    Saikosaponin B4 是一种柴胡皂苷,分离自柴胡的根。Saikosaponin B4选择性地抑制 ACTH 诱导的脂解作用。
    • ¥ 538
    现货
    规格
    数量
  • Leukotriene B4 dimethyl amide
    Leukotriene B4 dimethyl amide
    T3761883024-92-4
    LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes.
    • 待估
    35日内发货
    规格
    数量
  • Leukotriene B4
    白三烯 B4, 5(S),12(R)-DiHETE
    T1404571160-24-2
    Leukotriene B4 (LTB4) 是一种通过 5-脂氧合酶途径从花生四烯酸衍生而来的化合物,可介导某些炎症和免疫反应。Leukotriene B4 诱导中性粒细胞胞外陷阱阻碍肺孢子菌的清除。
    • 待估
    35日内发货
    规格
    数量
  • Lipoxin B4 methyl ester
    T3830897589-07-6
    Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4 . LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.
    • 待估
    35日内发货
    规格
    数量
  • 12-epi Leukotriene B4
    12-epi Leukotriene B4
    T3797083709-73-3
    Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. The products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis products are 50:50 mixtures at C-12, but are almost exclusively trans at C-6. Thus, the non-enzymatic hydrolysis product of LTA4 is 6-trans-12-epi LTB4. 12-epi LTB4 is an isomer which would not be expected to occur in either non-enzymatic hydrolysis products, or in the enzymatic products of LTA4 hydrolase. Compared to LTB4, 12-epi LTB4 has significantly reduced activity for the LTB4 receptor on human neutrophils (IC50 of 7.5 mM), and on guinea pig lung membranes with a (Ki of 4.7 mM). 12-epi LTB4 is an weak agonist at both the recombinant human BLT1 and BLT2 receptors, requiring approximately 10 mM for full activation of the receptor.
    • 待估
    35日内发货
    规格
    数量
  • Procyanidol B4
    Procyanidin B4, 原花青素B4
    TN115129106-51-2
    Procyanidin B4 reveals significant antioxidant activity
    • 待估
    35日内发货
    规格
    数量
  • 14,15-dehydro leukotriene b4
    14,15-dehydro Leukotriene B4
    T37260114616-11-4
    Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. At least two LTB4 receptors, termed BLT1 and BLT2, have been identified. 14,15-dehydro LTB4 is a LTB4 receptor antagonist that has a higher binding affinity for BLT1, demonstrating a Ki value of 27 nM, compared to BLT2, which has a Ki value of 473 nM. 14,15-dehydro LTB4 inhibits LTB4-induced release of lysozymes from rat polymorphonuclear leukoctyes with an IC50 value of 1 μM.
    • 待估
    35日内发货
    规格
    数量
  • Leukotriene B4 Ethanolamide
    T37619877459-63-7
    The effects of Leukotriene B4 (LTB4) are mediated by two known receptors, BLT1 and BLT2. LTB4 is a high affinity ligand for BLT1, and many of its pro-inflammatory effects are believed to be transduced through this receptor. The BLT2 is more enigmatic, in that LTB4 is not a high-affinity ligand, nor is it clear that BLT2 activation promotes inflammation. LTB4 ethanolamide (LTB4-EA) is a theoretical 5-LO metabolite of arachidonoyl ethanolamide (AEA). In CHO cells transfected with human BLTR1, LTB4-EA was a potent antagonist with about three times greater affinity for the receptor than LTB4 (Ki = 1.22 nM versus 3.88 nM). LTB4-EA antagonizes the LTB4-induced contractions of guinea pig lung parenchyma with an EC50 of 10 nM. LTB4-EA thus represents a potential endogenous anti-inflammatory compound functioning as a natural antagonist of BLTR1.
    • 待估
    35日内发货
    规格
    数量
  • A12B4C3
    A-12-B-4-C-3,A 12 B 4 C 3,A12 B4 C3,A12-B4-C3
    T235911005129-80-5
    A12B4C3 is a selective inhibitor of hPNKP phosphatase.
    • ¥ 3560
    5日内发货
    规格
    数量
  • 20-hydroxy Leukotriene B4
    20-hydroxy Leukotriene B4
    T3808779516-82-8
    20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki = 13.3 nM). However, 20-hydroxy LTB4 is as active as LTB4 in contracting parenchymal strips from guinea pig lung. 20-hydroxy LTB4 retains considerable ligand binding affinity at the BLT2 receptor, but does not appear to function as an agonist.
    • 待估
    35日内发货
    规格
    数量
  • Leukotriene B4-3-aminopropylamide
    LTB4-3-aminopropylamide
    T8450489596-43-0
    Leukotriene B4 (LTB4)-3-aminopropylamide is an analog of LTB4 that exhibits potent and selective binding to the BLT1 receptor with Ki values of 5.1 nM at BLT1 and 1,227 nM at BLT2, indicating its high affinity for BLT1 over BLT2. This compound's effects are mediated through interactions with two receptors, BLT1 and BLT2.
    • 待询
    8-10周
    规格
    数量
  • Malformin-B4
    T125793149596-55-4
    Malformin-B4 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125793,CAS号为 149596-55-4。
    • 待询
    规格
    数量
  • 18-carboxy dinor Leukotriene B4
    18-carboxy dinor LTB4
    T84506102674-12-4
    18-Carboxy dinor Leukotriene B4 (18-carboxy dinor LTB4) represents a β-oxidation metabolite of Leukotriene B4 (LTB4). Initially, LTB4 is metabolized in the liver to 20-carboxy LTB4, which subsequently undergoes β-oxidation to form 18-carboxy dinor LTB4.
    • 待询
    8-10周
    规格
    数量
  • 5-oxo Leukotriene B4
    5-keto LTB4
    T84978195061-92-8
    5-Oxo Leukotriene B4 (5-oxo LTB4) serves as an intermediate metabolite in the production of 12-oxo LTB4.
    • 待询
    8-10周
    规格
    数量
  • Valtrate hydrine B4
    T880318296-48-5
    Valtrate hydrine B4 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T8803,CAS号为 18296-48-5。
    • 待询
    规格
    数量
  • Dermaseptin-B4
    T82581210890-56-5
    Dermaseptin-B4为来源于南美洲树蛙Phyllomedusa bicolor皮肤分泌物的一种抗菌肽。
    • 待询
    规格
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  • Bleomycin B4
    T736069060-11-1
    Bleomycin B4 (Phleomycin F),一种具有抗肿瘤活性的抗生素,常用于癌症研究。
    • 待询
    规格
    数量
  • Arylomycin B4
    芳桥霉素 B4
    TN9076459844-27-0
    Arylomycin B4 是一种脂六肽抗生素 (antibiotic),专门针对革兰氏阳性菌。
    • 待询
    规格
    数量