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Anti-EPHB4 Monoclonal Antibody (1N998) 是一种 Mouse 抗体,靶向 EPHB4。Anti-EPHB4 Monoclonal Antibody (1N998) 可用于 IHC。
别名 TYRO11, MYK1, LMPHM7, HTK, HFASD, CMAVM2
Anti-EPHB4 Monoclonal Antibody (1N998) 是一种 Mouse 抗体,靶向 EPHB4。Anti-EPHB4 Monoclonal Antibody (1N998) 可用于 IHC。

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| 产品描述 | Anti-EPHB4 Monoclonal Antibody (1N998) is a Mouse antibody targeting EPHB4. Anti-EPHB4 Monoclonal Antibody (1N998) can be used in IHC. |
| 别名 | TYRO11, MYK1, LMPHM7, HTK, HFASD, CMAVM2 |
| Ig Type | IgG2a |
| 克隆号 | 1N998 |
| 反应种属 | Human |
| 应用 | IHC |
| 推荐剂量 | IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | EPH receptor B4 (EphB4), with 987-amino acid protein (about 108kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptor tyrosine kinases and their ligands, the ephrins, regulate numerous biological processes in developing and adult tissues and have been implicated in cancer progression and in pathological forms of angiogenesis. EphB4 acts as a negative regulator of blood vessel branching and vascular network formation, switching the vascularization program from sprouting angiogenesis to circumferential vessel growth. EphB4 and its ligand ephrinB2 express in several kinds of tumor cells and correlate with tumorigenesis. EphB4 is thus a potential candidate as a predictor of disease outcome in several kinds of tumor and as target for novel therapy. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of EphB4 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | EPHB4 |
| 基因ID | |
| 蛋白名称 | Ephrin type-B receptor 4 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |