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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-HAS1 Monoclonal Antibody (4B42)

Synonyms: HAS
货号 TMAT-1462 一键复制产品信息
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Anti-HAS1 Monoclonal Antibody (4B42) 是一种 Mouse 抗体，靶向 HAS1。Anti-HAS1 Monoclonal Antibody (4B42) 可用于 IF,FCM。

Anti-HAS1 Monoclonal Antibody (4B42)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1462

别名 HAS

Anti-HAS1 Monoclonal Antibody (4B42) 是一种 Mouse 抗体，靶向 HAS1。Anti-HAS1 Monoclonal Antibody (4B42) 可用于 IF,FCM。

Anti-HAS1 Monoclonal Antibody (4B42)
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产品介绍

生物活性
产品描述
Anti-HAS1 Monoclonal Antibody (4B42) is a Mouse antibody targeting HAS1. Anti-HAS1 Monoclonal Antibody (4B42) can be used in IF,FCM.
别名
HAS
Ig Type
IgG2b
克隆号
4B42
反应种属
Human
应用IFFCM
推荐剂量
IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human HAS1 (AA: (74-399)) expressed in E. Coli.
抗原种属
Human
基因名称
HAS1
基因ID
3036
蛋白名称
Hyaluronan synthase 1
Uniprot ID
Q92839
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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