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Anti-HLA-B Monoclonal Antibody (4C830)

Synonyms: SPDA1, HLA-Cw, HLAB, Bw-50, Bw-47, B-5001, B-4901, AS
货号 TMAT-0647 一键复制产品信息
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Anti-HLA-B Monoclonal Antibody (4C830) 是一种 Mouse 抗体,靶向 HLA-B。Anti-HLA-B Monoclonal Antibody (4C830) 可用于 WB,IHC,IF,FCM。

Anti-HLA-B Monoclonal Antibody (4C830)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0647

别名 SPDA1, HLA-Cw, HLAB, Bw-50, Bw-47, B-5001, B-4901, AS

Anti-HLA-B Monoclonal Antibody (4C830) 是一种 Mouse 抗体,靶向 HLA-B。Anti-HLA-B Monoclonal Antibody (4C830) 可用于 WB,IHC,IF,FCM。

Anti-HLA-B Monoclonal Antibody (4C830)
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产品介绍


生物活性
产品描述
Anti-HLA-B Monoclonal Antibody (4C830) is a Mouse antibody targeting HLA-B. Anti-HLA-B Monoclonal Antibody (4C830) can be used in WB,IHC,IF,FCM.
别名
SPDA1, HLA-Cw, HLAB, Bw-50, Bw-47, B-5001, B-4901, AS
Ig Type
IgG1
克隆号
4C830
反应种属
Human
应用WBIHCIFFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human HLA-B (AA: 241-362) expressed in E. Coli.
抗原种属
Human
基因名称
HLA-B
基因ID
蛋白名称
HLA class I histocompatibility antigen, B alpha chain
Uniprot ID
化学信息
分子量Theoretical: 40.5 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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