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Targets Recommended: BCL

169

抑制剂 & 化合物

64

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化合物库

316

重组蛋白

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Cat. No. Product Name
L9000 细胞凋亡化合物库

1760 compounds
1760 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选;

化合物库

细胞凋亡化合物库
Cat.No: L9000
Compounds: 1760
Cat. No. Product Name Target Signaling Pathways
T38622 Bcl-xL antagonist 2

BCL Apoptosis
Bcl-xL antagonist 2 是一种有效的选择性 Bcl-xL 拮抗剂,IC50 为 91 nM,Ki 为 65 nM。 Bcl-xL antagonist 2 可诱导癌细胞凋亡,可用于慢性淋巴细胞白血病和非霍奇金淋巴瘤的研究。
T10483 Lisaftoclax

Bcl-2/Bcl-xl inhibitor 1,APG-2575

BCL Apoptosis
Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1) 是一种双重 Bcl-2Bcl-xl 抑制剂(IC50:2 nM 和 5.9 nM),具有抗肿瘤活性。
T33467 MOMIPP

PI3K PI3K/Akt/mTOR signaling
MOMIPP 是一种 PIKfyve 抑制剂,是一种巨胞饮作用的诱导剂,可穿过血脑屏障 (BBB)。
T39961 Bcl-2-IN-2

Bcl-2-IN-2 is a highly potent and selective inhibitor targeting Bcl-2 and Bcl-xL. It displays an IC50 value of 0.034 nM, suggesting its strong inhibitory activity specifically against Bcl-2. Additionally, Bcl-2-IN-2 exhibits an IC50 value of 43 nM against Bcl-xL, demonstrating over 1000-fold selectivity for Bcl-2 compared to Bcl-xL.
T17018 TCPOBOP

BCL Apoptosis
TCPOBOP 是一种组成型雄烷受体激动剂,可诱导强大的肝细胞增殖和肝肿大。它通过改变 Bcl-2 蛋白来减少 Fas 诱导的小鼠肝损伤。
T11969 MCL-1/BCL-2-IN-2

Others Others
MCL-1/BCL-2-IN-2 is a potent and selective Bcl-2 and Mcl-1 dual inhibitor.
T12824L S55746

BLC201

BCL Apoptosis
S55746 (BLC201) 是一种有效、可口服、选择性的BCL-2抑制剂,其Ki 值和Kd 值分别为 1.3 nM 和 3.9 nM。它具有抗肿瘤活性且毒性低。
T11971 MCL-1/BCL-2-IN-4

Others Others
MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.
T11970 MCL-1/BCL-2-IN-3

Others Others
MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.
T11968 MCL-1/BCL-2-IN-1

BCL Apoptosis
MCL-1/BCL-2-IN-2 (Compound Nap-1) 是一种有效的选择性 Mcl-1和 Bcl-2双重抑制剂,IC50分别为 4.45 和 3.18 μM。
T2099 ABT-737

Mitophagy; BCL; Autophagy Apoptosis; Autophagy
ABT737 是 BH3 模拟物,是Bcl-2Bcl-xL 和Bcl-w 抑制剂,EC50分别为 30.3 nM、78.7 nM 和 197.8 nM。它诱导自噬,有研究急性髓系白血病的潜力。它还诱导 BCL-2/BAX 复合物的破坏和 BAK 依赖性。
T11944 Maritoclax

Marinopyrrole A

BCL Apoptosis
Maritoclax (Marinopyrrole A) 是一种新型特异性 Mcl-1 抑制剂,IC50值为 10.1 μM,对 BCL-xl 的 IC50值 > 80 μM。
T1980 HA14-1

BCL Apoptosis
HA14-1 是一种 Bcl-2/Bcl-xL 拮抗剂,与 Bcl-2 上的特定口袋结合,IC50约为 9 μM。
T6650 Sabutoclax

BI-97C1

BCL Apoptosis
Sabutoclax (BI-97C1) 是一种泛 Bcl-2 抑制剂,包括 Bcl-xL、Bcl-2、Mcl-1 和 Bfl-1,IC50 分别为 0.31 μM、0.32 μM、0.20 μM 和 0.62 μM。
T14071 A-385358

BCL Apoptosis
A-385358 是一种特异性 Bcl-xL 抑制剂,对 Bcl-xL 和 Bcl-2 的 Ki 分别为 0.80 nM 和 67 nM。
T5108 ML311

BCL Apoptosis
ML311 是 Mcl-1/Bim 相互作用的一种选择性抑制剂。
T5408 BI-3802

BCL Apoptosis
BI-3802 能够抑制 BCL6 的Bric-à-brac (BTB) 结构域,IC50 ≤3 nM。它可诱导 BCL6 蛋白聚集,并促进 E3 连接酶SIAH1介导的蛋白降解。BI-3802显示出抗肿瘤活性。
T2632 A-1210477

Apoptosis; BCL Apoptosis
A-1210477 是一种选择性的MCL-1有效抑制剂,Ki 值为 0.45 nM。它特异性结合 MCL-1,并以 MCL-1 依赖性方式促进癌细胞凋亡。
T14834 BT2

3,6-二氯-2-苯并噻吩羧酸

BCL Apoptosis
BT2 是 BCKDC 激酶(BDK)抑制剂,IC50值为 3.19 μM。它也是一种选择性的Mcl-1抑制剂,Ki 值为 59 μM。BT2 与 BDK 结合触发 N 端结构域的螺旋运动,导致 BDK 从支链 α-酮酸脱氢酶复合物 (BCKDC) 中解离。
T5346 S63845

BCL Apoptosis
S63845 是一种选择性骨髓细胞白血病 1 抑制剂,结合人 MCL1的 Kd 值为 0.19 nM。
T6281 TW-37

TW 37

BCL Apoptosis
TW-37 是重组 Bcl-2Bcl-xL 和 Mcl-1 的非肽抑制剂,Ki 值分别为 0.26、0.29和1.11μM
T14376 AZD4320

BCL Apoptosis
AZD4320 是一种BCL2/BCLxL 双重抑制剂,是 BH-3 类似物,对 KPUM-MS3、KPUM-UH1 和 STR-428 细胞,IC50 值分别为 26 nM、17 nM 和 170 nM。
T2453 BAM7

BCL Apoptosis
BAM7 是一种促凋亡 Bax 的直接和特异性激活剂,IC50为 3.3 μM。
T14561 BI-3812

BCL Apoptosis
BI-3812 是一种高效的BCL6抑制剂,具有抗肿瘤活性,能够抑制 BCL6 的 BTB 结构域,IC50值 ≤3 nM。
T6749 A-1331852

BCL Apoptosis
A1331852是一种具有口服活性的BCL-XL 选择性抑制剂,Ki 值小于10 pM。它可用于治疗癌症、免疫和自身免疫疾病。
T4089 FX1

Apoptosis; BCL Apoptosis
FX1 是一种强效特异性BCL6抑制剂,IC50大约为 35 μM。
T6034 UMI-77

UMI77,UMI 77

BCL Apoptosis
UMI-77是一种选择性的Mcl-1抑制剂,结合到Mcl-1的 BH3 结合沟,Ki 值为 490 nM,对 Bcl-2 家族的其他成员具有选择性。
T2101 Navitoclax

ABT-263

BCL Apoptosis
Navitoclax (ABT-263) 是一种 Bcl-2 抑制剂,可与 Bcl-xL、Bcl-2Bcl-w 等蛋白结合 (Ki<1 nM),具有有效性和口服活性。Navitoclax 具有抗肿瘤活性,可以诱导细胞凋亡。
T7538 Tetraethylammonium chloride

Potassium Channel Membrane transporter/Ion channel
Tetraethylammonium chloride 是非选择性钾通道阻滞剂。它是有机阳离子转运蛋白的良好底物,并具有抗肿瘤特性。
T3940 CID5721353

BCL6 inhibitor

Apoptosis; BCL Apoptosis
CID5721353 (BCL6 inhibitor) 是一种 B 细胞淋巴瘤 6 抑制剂,IC50为 212 μM,Ki 值为 147 μM。它可在体内外破坏 BCL6/辅助阻遏物复合物,并显示与 BTB 沟内的关键位点结合。
T6748 A-1155463

A 1155463,A1155463,醋酸艾塞那肽

BCL Apoptosis
A-1155463是一种高效选择性的BCL-XL 抑制剂,对 BCL-XL 具有皮摩尔的结合亲和力,在Molt-4细胞中的EC50值为70 nM。
T6778 BDA-366

BCL Apoptosis
BDA-366 是一种有效的 Bcl2 拮抗剂,以高亲和力和选择性 (Ki = 3.3 nM) 结合 Bcl2-BH4 结构域。 BDA-366 诱导 Bcl2 的构象变化,从而消除其抗凋亡功能,将其从存活分子转变为细胞死亡诱导剂。 BDA-366 抑制肺癌细胞的生长。
T5210 BAI1

Apoptosis; BCL Apoptosis
BAI1 是一种选择性凋亡因子BAX 变构抑制剂。它结合 BAX 并变构抑制其激活,具有潜力研究 BAX 依赖性细胞死亡介导的疾病。
T6258 Zibotentan

ZD4054

Apoptosis; Endothelin Receptor Apoptosis; GPCR/G Protein
Zibotentan (ZD4054) 是一种选择性的,具有口服活性的内皮素 A (ETA) 受体拮抗剂,Ki 为 13 nM。它具有抗癌作用,可研究去势抵抗性前列腺癌。
T5104 BTSA1

Apoptosis; BCL Apoptosis
BTSA1 是一种有口服活性的 BAX 激活剂,IC50为 250 nM,EC50为 144 nM。它以高亲和力和特异性与 N 末端激活位点结合,并诱导 BAX 发生构象变化,从而导致BAX 介导的细胞凋亡。
T8656 CAY10404

3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Apoptosis; Akt; COX Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience; PI3K/Akt/mTOR signaling
CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) 是一种有效且高度选择性的 COX-2 和 COX-1 抑制剂。 它还是 PKB/Akt 和 MAPK 信号通路的有效抑制剂,可诱导 NSC-LC 细胞凋亡,具有镇痛、抗炎和抗癌活性。
T16028 IMB-XH1

Mcl1-IN-2,7-[(2-吡啶基氨基)-2-噻吩基甲基]-8-喹啉醇

BCL; Antibacterial Apoptosis; Microbiology/Virology
IMB-XH1 (Mcl1-IN-2) 是一种骨髓细胞因子 1 抑制剂。它也是非竞争性的 Delhi metallo-β-lactamase(NDM-1) 抑制剂。它对金属 β-内酰胺酶 NDM-1,IMP-4,ImiS 和 L1 的 IC50值分别为 0.4637 μM,3.980 μM,0.2287 μM 和 1.158 μM。
T15771 Lobaplatin

D-19466,络铂

DNA Alkylation DNA Damage/DNA Repair
Lobaplatin (D-19466) 是一种铂 (II) 复合物的非对映混合物,是一种有前途的抗肿瘤化疗药物,在多种肿瘤类型的患者中具有活性。
T5827 BI-6C9

Apoptosis; Others; Mitochondrial Metabolism Apoptosis; Metabolism; Others
BI-6C9 是一种高特异性的 BH3 相互作用结构域抑制剂,可阻止线粒体外膜电位和线粒体分裂,并保护细胞免受线粒体凋亡诱导因子释放和不依赖 caspase 的细胞死亡。
T12041 MIM1

Inhibitor of Mcl-1

BCL Apoptosis
MIM1 (Inhibitor of Mcl-1) 是一种骨髓细胞因子 1 抑制剂。
T6275 Obatoclax Mesylate

Obatoclax,GX15-070,奥巴克拉甲磺酸盐

BCL; Parasite; Autophagy Apoptosis; Autophagy; Microbiology/Virology
Obatoclax Mesylate (GX15-070) 是泛 BCL-2家族蛋白抑制剂,对 BCL-2 的 Ki 值为 220 nM。它是 BH3 模拟物,具有抗癌和广谱抗寄生虫活性。它诱导自噬依赖性细胞死亡,并靶向细胞周期蛋白 D1 进行蛋白酶体降解。
T12186 Navitoclax-piperazine

ABT-263-piperazine

BCL; Ligands for Target Protein for PROTAC Apoptosis; PROTAC
Navitoclax-piperazine (ABT-263-piperazine) 是一种特大型 B 细胞淋巴瘤(BCL-XL)抑制剂。它和 E3 泛素连接酶的 VHL 配体可用来合成 PROTAC DT2216。
T2119 Venetoclax

GDC-0199,ABT 199,维奈妥拉,ABT-199,ABT199

BCL; Autophagy Apoptosis; Autophagy
Venetoclax (ABT-199) 是一种 Bcl-2 抑制剂 (Ki<0.01 nM),具有高效性、选择性和口服活性。Venetoclax 与 Bcl-xL 和 Bcl-W 的亲和力降低了 3 个数量级(Kis=48/245 nM)。Venetoclax 可以诱导自噬和凋亡。
T9083 TC11

CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

BCL; Caspase; CDK Apoptosis; Cell Cycle/Checkpoint; Proteases/Proteasome
TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) 是一种有效的肿瘤细胞增殖抑制剂,并通过激活 caspase-3、8 和 9 诱导细胞凋亡。在长时间有丝分裂阻滞期间,它诱导 MCL1降解导致凋亡。它作为苯酞酰亚胺衍生物在结构上与免疫调节药物相关。
T1493 BH3I-1

BHI1

BCL; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
BH3I-1 (BHI1) 是一种Bcl-2家族拮抗剂,作用于p53/mDM2,Kd 为 5.3 μM。它抑制BakBH3 肽与Bcl-xL 结合,Ki 为 2.6 μM。
T13416 ZX-29

ALK Angiogenesis; Tyrosine Kinase/Adaptors
ZX-29 是一种选择性ALK 抑制剂,对ALK、ALK L1196M 和ALK G1202R 的IC50分别为 2.1 nM、1.3 nM 和 3.9 nM。它还可诱导保护性自噬并具有抗肿瘤作用。它通过诱导内质网应激来诱导细胞凋亡,并克服了由ALK 突变引起的细胞抗性。
T6941 PI-1840

PI 1840

PARP; Proteasome Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome; Ubiquitination
PI-1840 是一种高效的、选择性的蛋白酶体chymotrypsin-like (CT-L)抑制剂,IC50=27nM。
T39910 Desmorpholinyl Navitoclax-NH-Me

Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me

BCL Apoptosis
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].
T62443 Bcl-2/Mcl-1-IN-2

Bcl-2/Mcl-1-IN-2 是一种 Bcl-2 (Ki: 4.70 μM) 和 Mcl-1 (Ki: 0.88 μM) 抑制剂。Bcl-2/Mcl-1-IN-2 能够用于研究癌症。
T6396 (R)-(-)-Gossypol acetic acid

(-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101醋酸,AT101,AT101 acetate

BCL; Autophagy Apoptosis; Autophagy
(R)-(-)-Gossypol acetic acid (AT101 acetate) 是天然产物 Gossypol 的左旋异构体,与 Bcl-2Bcl-xL 和 Mcl-1 结合,Ki 为 0.32 μM、0.48 μM 和 0.18 μM。

化合物

Bcl-xL antagonist 2
Cat.No: T38622
Synonym:
Target: BCL
Lisaftoclax
Cat.No: T10483
Synonym: Bcl-2/Bcl-xl inhibitor 1,APG-2575
Target: BCL
MOMIPP
Cat.No: T33467
Synonym:
Target: PI3K
Bcl-2-IN-2
Cat.No: T39961
Synonym:
Target:
TCPOBOP
Cat.No: T17018
Synonym:
Target: BCL
MCL-1/BCL-2-IN-2
Cat.No: T11969
Synonym:
Target: Others
S55746
Cat.No: T12824L
Synonym: BLC201
Target: BCL
MCL-1/BCL-2-IN-4
Cat.No: T11971
Synonym:
Target: Others
MCL-1/BCL-2-IN-3
Cat.No: T11970
Synonym:
Target: Others
MCL-1/BCL-2-IN-1
Cat.No: T11968
Synonym:
Target: BCL
ABT-737
Cat.No: T2099
Synonym:
Target: Mitophagy, BCL, Autophagy
Maritoclax
Cat.No: T11944
Synonym: Marinopyrrole A
Target: BCL
HA14-1
Cat.No: T1980
Synonym:
Target: BCL
Sabutoclax
Cat.No: T6650
Synonym: BI-97C1
Target: BCL
A-385358
Cat.No: T14071
Synonym:
Target: BCL
ML311
Cat.No: T5108
Synonym:
Target: BCL
BI-3802
Cat.No: T5408
Synonym:
Target: BCL
A-1210477
Cat.No: T2632
Synonym:
Target: Apoptosis, BCL
BT2
Cat.No: T14834
Synonym: 3,6-二氯-2-苯并噻吩羧酸
Target: BCL
S63845
Cat.No: T5346
Synonym:
Target: BCL
TW-37
Cat.No: T6281
Synonym: TW 37
Target: BCL
AZD4320
Cat.No: T14376
Synonym:
Target: BCL
BAM7
Cat.No: T2453
Synonym:
Target: BCL
BI-3812
Cat.No: T14561
Synonym:
Target: BCL
A-1331852
Cat.No: T6749
Synonym:
Target: BCL
FX1
Cat.No: T4089
Synonym:
Target: Apoptosis, BCL
UMI-77
Cat.No: T6034
Synonym: UMI77,UMI 77
Target: BCL
Navitoclax
Cat.No: T2101
Synonym: ABT-263
Target: BCL
Tetraethylammonium chloride
Cat.No: T7538
Synonym:
Target: Potassium Channel
CID5721353
Cat.No: T3940
Synonym: BCL6 inhibitor
Target: Apoptosis, BCL
A-1155463
Cat.No: T6748
Synonym: A 1155463,A1155463,醋酸艾塞那肽
Target: BCL
BDA-366
Cat.No: T6778
Synonym:
Target: BCL
BAI1
Cat.No: T5210
Synonym:
Target: Apoptosis, BCL
Zibotentan
Cat.No: T6258
Synonym: ZD4054
Target: Apoptosis, Endothelin Receptor
BTSA1
Cat.No: T5104
Synonym:
Target: Apoptosis, BCL
CAY10404
Cat.No: T8656
Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T
Target: Apoptosis, Akt, COX
IMB-XH1
Cat.No: T16028
Synonym: Mcl1-IN-2,7-[(2-吡啶基氨基)-2-噻吩基甲基]-8-喹啉醇
Target: BCL, Antibacterial
Lobaplatin
Cat.No: T15771
Synonym: D-19466,络铂
Target: DNA Alkylation
BI-6C9
Cat.No: T5827
Synonym:
Target: Apoptosis, Others, Mitochondrial Metabolism
MIM1
Cat.No: T12041
Synonym: Inhibitor of Mcl-1
Target: BCL
Obatoclax Mesylate
Cat.No: T6275
Synonym: Obatoclax,GX15-070,奥巴克拉甲磺酸盐
Target: BCL, Parasite, Autophagy
Navitoclax-piperazine
Cat.No: T12186
Synonym: ABT-263-piperazine
Target: BCL, Ligands for Target Protein for PROTAC
Venetoclax
Cat.No: T2119
Synonym: GDC-0199,ABT 199,维奈妥拉,ABT-199,ABT199
Target: BCL, Autophagy
TC11
Cat.No: T9083
Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11
Target: BCL, Caspase, CDK
BH3I-1
Cat.No: T1493
Synonym: BHI1
Target: BCL, E1/E2/E3 Enzyme
ZX-29
Cat.No: T13416
Synonym:
Target: ALK
PI-1840
Cat.No: T6941
Synonym: PI 1840
Target: PARP, Proteasome
Desmorpholinyl Navitoclax-NH-Me
Cat.No: T39910
Synonym: Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me
Target: BCL
Bcl-2/Mcl-1-IN-2
Cat.No: T62443
Synonym:
Target:
(R)-(-)-Gossypol acetic acid
Cat.No: T6396
Synonym: (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101醋酸,AT101,AT101 acetate
Target: BCL, Autophagy
Cat. No. Product Name Target Signaling Pathways
T3824 Jaceosidin

Apoptosis; BCL; COX; UGT Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience
Jaceosidin 是从毛莲蒿中得到的一种黄酮类天然产物,可激活Bax,下调 Mcl-1 和 c-FLIP 的表达,诱导癌细胞凋亡。它能够降低炎性因子水平,激活 NF-κB,抑制COX-2的表达,具有抗癌和抗炎作用。
TN1406 Dihydrokaempferol

香橙素,Aromadendrin

Apoptosis; BCL Apoptosis
Dihydrokaempferol (Aromadendrin) 是从紫荆花中分离得到的一种天然产物,诱导凋亡并抑制 Bcl-2Bcl-xL 的表达,可以作为抗关节炎的良好新药候选。
T8213 Isolinderalactone

NOS; STAT Immunology/Inflammation; JAK/STAT signaling; Stem Cells
Isolinderalactone 具有抗炎和抗癌能力,具有中等的 iNOS 抑制活性,IC50 值为 0.30 uM。
TN3967 Epieriocalyxin A

ERK; BCL; ROS; Caspase; DNA/RNA Synthesis; JNK Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Proteases/Proteasome
Epieriocalyxin A 可以抑制 Caco-2 结肠癌细胞的生长。它可能是未来结肠癌治疗的潜在药物。
T7979 2-Hydroxychalcone

2-(2-Hydroxybenzal)Acetophenone,2-羟基查酮

Apoptosis; BCL; Others; NF-κB Apoptosis; NF-κB; Others
2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) 是一种天然黄酮,可通过下调 Bcl-2 诱导凋亡,也可抑制NF-kB 的激活。它是抗氧化剂,抑制脂质过氧化,还可抑制三阴性乳腺癌细胞的侵袭。
T6518 Gossypol

Pogosin,BL 193,棉酚,NSC 56817

BCL; Dehydrogenase Apoptosis; Metabolism
Gossypol (BL 193) 是一种多酚醛,可渗透细胞并作为几种脱氢酶的抑制剂。它分别与 Bcl-xL 蛋白和Bcl-2蛋白结合,Ki 值分别为 0.5-0.6 μM 和 0.2-0.3 mM。
T6S0052 Chelerythrine

Toddalin,Broussonpapyrine,白屈菜红碱,Cheleritrine

Apoptosis; BCL; PKC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling
Chelerythrine (Broussonpapyrine) 是一种天然生物碱,为有效、选择性的 Ca2+/磷脂依赖性PKC 拮抗剂,IC50值为 0.7 μM。它具有抗肿瘤、抗糖尿病、抗炎的活性。它抑制BclXL-Bak BH3肽结合,IC50为 1.5 μM,并从 BclXL 取代了 Bax。它诱导细胞凋亡和自噬。
T6S1653 Albiflorin

Alibiflorin,芍药内酯苷

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Albiflorin (Alibiflorin) 是一种牡丹根中的主要成分,是一种单萜糖苷。它具有神经保护、抗炎、抗氧化和缓解疼痛作用。
T3419 Chelerythrine chloride

白屈菜红碱,盐酸白屈菜红碱

Apoptosis; BCL; PKC; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling
Chelerythrine chloride 是一种可渗透细胞的蛋白激酶 C 抑制剂,对磷酸盐受体具有竞争性,而对 ATP 是非竞争性的。它诱导细胞凋亡和自噬。
T5S2358 Dehydrocorydaline

Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine

BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
Dehydrocorydaline (13-Methylpalmatine) 是一种生物碱。它调节Bax,Bcl-2蛋白表达,激活caspase-7,caspase-8,并使PARP 失活。它能增强p38 MAPK 活化,具有抗炎、抗癌等功效。它具有强大的抗疟疾作用,并具低细胞毒性。
T2S0500 Ilexsaponin A

毛冬青皂苷A,毛冬青皂苷甲,Ilexsaponin A1

Others Others
Ilexsaponin A (Ilexsaponin A1)1 是分离自冬凌草的根中,利用抗凋亡途径减轻缺血再灌注引起的心肌损伤。它能够减少心肌梗塞的大小,减少 LDH,AST 和 CK-MB 的血清水平,促进细胞活力并抑制缺氧/复氧心肌细胞的凋亡。
T10990 Dehydrocorydaline chloride

盐酸脱氢紫堇碱,13-Methylpalmatine chloride

BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
Dehydrocorydaline chloride (13-Methylpalmatine chloride) 是生物碱。Dehydrocorydaline 调节 Bax,Bcl-2蛋白表达;激活 caspase-7,caspase-8,并使 PARP 失活。它能增强 p38 MAPK 活化,具有抗炎、抗癌等功效。它具有强大的抗疟疾作用,并具低细胞毒性。
T6185 Gambogic Acid

藤黄酸,Beta-Guttiferrin,藤黄酸 A,Guttatic Acid,Guttic Acid

BCL; Autophagy Apoptosis; Autophagy
Gambogic Acid (Guttic Acid) 是来自藤黄树的一种藤黄树脂,抑制 Bcl-XL、Bcl-2Bcl-W、Bcl-B、Bfl-1和 Mcl-1,IC50分别为 1.47 μM、1.21 μM、2.02 μM、0.66 μM、1.06 μM 和 0.79 μM。
T2S2362 Dehydrocorydaline nitrate

去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱

BCL; Others; PARP; p38 MAPK; Caspase; Parasite; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Others; Proteases/Proteasome
Dehydrocorydaline nitrate 是生物碱。Dehydrocorydaline 调节 Bax,Bcl-2蛋白表达,激活 caspase-7,caspase-8,并使 PARP 失活。它能增强 p38 MAPK 活化,具有抗炎、抗癌、抗疟疾等功效。
T5679 (E)-Ferulic acid

trans-Ferulic acid,反式阿魏酸,(E)-Coniferic acid

BCL; Ferroptosis; Wnt/beta-catenin; Endogenous Metabolite Apoptosis; Cytoskeletal Signaling; Metabolism; Stem Cells
(E)-Ferulic acid ((E)-Coniferic acid) 是阿魏酸的异构体,阿魏酸是在植物细胞壁中丰富存在的芳香族天然产物。 它引起 β-catenin 的磷酸化,导致其蛋白酶体降解,增加促凋亡因子 Bax 的表达,降低促生存因子的表达。它在人肺癌细胞系 H1299 中发挥抗增殖和抗迁移作用。
T2764 (S)-10-Hydroxycamptothecin

10-羟喜树碱,10-羟基喜树碱,10-Hydroxycamptothecin,10-HCPT

Apoptosis; Topoisomerase Apoptosis; DNA Damage/DNA Repair
(S)-10-Hydroxycamptothecin (10-HCPT) 是一种从喜树中分离的 DNA 拓扑异构酶 I 抑制剂。它显著诱导细胞凋亡,可研究肝癌、胃癌、结肠癌和白血病。
T3322 trans-Chalcone

Chalcone,反-查耳酮,查尔酮,Cinnamophenone,Chalkone

Apoptosis; Others; Antifungal; Fatty Acid Synthase Apoptosis; Metabolism; Microbiology/Virology; Others
trans-Chalcone (Chalkone) 是从 Aronia melanocarpa 果皮中分离出来的一种天然产物,是类黄酮前体的双酚核心结构。它是脂肪酸合酶和 α-淀粉酶的抑制剂,具有抗真菌和抗癌活性。
T3344 Ciwujianoside B

yemuoside YM,刺五加皂苷 B,acanthopanax senticosides B,刺五加皂甙 B,Ciwujianoside-B

BCL; Others Apoptosis; Others
Ciwujianoside B (acanthopanax senticosides B) 是刺五加的主要成分,能缓解疲劳,增强记忆力,提高人的认知能力。
T2730 Gossypol (acetic acid)

(±)-Gossypol-acetic acid,Pogosin,AT101,醋酸棉酚,乙酸棉子酚,Gossypol acetic acid

BCL Apoptosis
Gossypol acetic acid (AT101) 是一种从棉籽中分离出来的多酚天然产物,分别与 Bcl-xL 蛋白和 Bcl-2蛋白结合,Ki 值分别为 0.5-0.6 μM 和 0.2-0.3 mM。
T2163 Dihydrocapsaicin

CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Others; TRP/TRPV Channel Membrane transporter/Ion channel; Others
Dihydrocapsaicin (CCRIS1589) 是一种天然来源的辣椒素,是TRPV1的选择性激动剂,同时可以增加 p-Akt 水平。它可以增强低温诱导的神经保护。
T2851 Daphnetin

7,8-Dihydroxycoumarin,Daphnetol,瑞香素

EGFR; PKA; PKC; Parasite; Autophagy Angiogenesis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
Daphnetin (7,8-Dihydroxycoumarin) 是从 Genus Daphne 中分离得到的香豆素衍生物,有抗氧化、抗炎、抗疟疾和解热作用,可用于凝血功能障碍、类风湿性关节炎等疾病的相关研究。
T4085 Paris saponin VII

重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Apoptosis; BCL; Others; PARP; p38 MAPK; Akt; Caspase; P-gp; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Membrane transporter/Ion channel; Neuroscience; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Paris saponin VII (Dioscini) 是从延龄草的根和根茎中分离的一种甾体皂苷。它减弱线粒体膜电位,增加凋亡相关蛋白的表达,并降低Bcl-2、caspase-9、caspase-3、PARP-1和p-Akt 的蛋白表达水平。它在 K562/ADR 细胞中诱导强烈的自噬,可研究白血病。
T7060 Amantadine

1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine

Others Others
Amantadine (1-Aminoadamantane) 是抗病毒药物,也是是 NMDA 型谷氨酸受体的弱拮抗剂,能促进高多巴胺的释放,并阻断多巴胺的再摄取。
T6S1917 Schisandrol B

Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

P450; Reactive Oxygen Species; Autophagy Autophagy; Immunology/Inflammation; Metabolism; NF-κB
Schisandrol B (Besigomsin) 是华中五味子的主要活性成分,具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生,也抑制 P-糖蛋白和CYP3A 的活性。
T1034 Docetaxel

多西他赛,NSC 628503,RP-56976,多烯紫杉醇

Apoptosis; Microtubule Associated; Endogenous Metabolite Apoptosis; Cytoskeletal Signaling; Metabolism
Docetaxel (RP-56976) 是紫杉醇的半合成类似物,是一种微管解聚抑制剂 (IC50=0.2 μM)。Docetaxel 可以减弱 bcl-2bcl-xL 基因表达的影响,具有诱导凋亡、抗肿瘤活性。
T3857 magnolin

木兰脂素,(+)-Magnolin,木兰苷

ERK MAPK
Magnolin 是辛夷的一种主要成分,靶向作用于ERK1和ERK2,IC50值分别为 87 和 16.5 nM,可抑制Ras/ERKs/RSK2信号通路。它在体内外降低肾脏氧化应激,抑制 caspase-3 活性,并增加 Bcl-2 表达,具有抗炎和抗氧化作用。
T6S1529 Cynarin

Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1R,​3R,​4S,​5R)​-,Cynarine,1,5-Dicaffeoylquinic acid,洋蓟素,金银花

Antioxidant; Antiviral; Influenza Virus; Reactive Oxygen Species Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; oxidation-reduction
Cynarin (1,5-Dicaffeoylquinic acid) 是一种抗窒息剂,具有抗氧化、抗组胺和抗病毒等多种生物活性。
T2S0410 Euphorbia factor L1

Euphorbiasteroid,大戟因子L1,大戟因子 L1

Apoptosis; P-gp Apoptosis; Membrane transporter/Ion channel; Neuroscience
Euphorbia factor L1 (Euphorbiasteroid) 可降低 Bcl-2,PI3K,AKT 和 mTOR 蛋白和 mRNA 水平,上调 caspase-9 and caspase-3 蛋白水平。它可诱导自噬,具有抗癌、抗脂肪生成、抗破骨细胞生成和多重耐药调节作用。
T5S2083 Puerarin 6''-O-Xyloside

Apoptosis; Caspase Apoptosis; Proteases/Proteasome
Puerarin 6''-O-Xyloside 是从葛根中分离得到的一种天然产物,可诱导线粒体介导的细胞凋亡通路,有抗炎和抗癌活性。
T3867 Alpinetin

山姜素,(-)-alpinetin

BCL; PPAR Apoptosis; DNA Damage/DNA Repair; Metabolism
Alpinetin ((-)-alpinetin) 是从草豆蔻中分离得到的一种黄酮类天然产物,能够活化PPAR-γ,具有抗炎、抗菌活性。它通过抑制增殖、调节 Bcl-2 家族和 XIAP 表达、释放细胞色素 c 和激活 caspase 具有很强的抗肝癌和胰腺癌细胞作用。
T7027 EURYCOMANONE

东革阿里提取物,Pasakbumin A

Others Others
Eurycomanone (Pasakbumin A) 能够抑制雌激素生成过程中磷酸二酯酶和芳香酶的活性,促进精子生成。它对 HepG2 细胞具有细胞毒性,能够上调 p53 和 Bax 以及下调 Bcl-2 ,诱导细胞凋亡。它具有抗癌活性,在浓度范围内以剂量依赖性方式抑制 A549 肺癌细胞增殖 从 5 到 20 微克/毫升。
T2795 Amygdalin

苦杏仁苷,Laetrile

Others Others
Amygdalin (Laetrile) 是一种植物葡萄糖苷,分离自蔷薇果实的果核中,如杏,桃,杏仁,樱桃和李子。
T6S1418 Praeruptorin C

Antioxidant; Calcium Channel Membrane transporter/Ion channel; Metabolism; oxidation-reduction
Praeruptorin C 是白花前胡中的一种主要成分,是钙拮抗剂,pD2′值为 5.7。
TN2254 Taccalonolide A

根薯酮内酯A,根薯酮内酯 A

Apoptosis; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Taccalonolide A 是从水田七根茎中分离得到的一种类固醇,具有细胞毒性和抗疟活性。它在体外对过表达 p 糖蛋白、多药耐药蛋白 7 细胞系有抑制作用,抑制 SK-OV-3 细胞生长的 IC50值为 622 nM。它是微管稳定剂,能引起 G2-M 期滞留、Bcl-2 磷酸化,并引发细胞凋亡。
T3S2344 β,β-Dimethylacrylshikonin

β,β-二甲基丙烯酰紫草素,Dimethylacrylshikonin,β, β-Dimethylacrylshikonin

ERK; HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; MAPK; Metabolism
β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) 是一种萘醌衍生物,从 Arnebia nobilis 中提取得到。它利用 PI3K 通路诱导 eNOS、VEGF 和 HIF-1α 的表达,促进血管生成,具有抗肿瘤活性。
T2860 Vanillyl Alcohol

4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol

Apoptosis; Others Apoptosis; Others
Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) 是一种酚类醇,具有抗血管生成、抗惊厥、抗炎、抗氧化、神经保护和抗伤害活性。它由香兰素衍生而来,在食品和饮料中用作调味剂。
TN2103 PROCYANIDIN C1

原花青素 C1,原花青素C1

Apoptosis Apoptosis
Procyanidin C1 是一种天然多酚,可造成 DNA 损伤,细胞周期停滞,诱导凋亡。它降低癌细胞中 Bcl-2 的蛋白水平,增强 BAX,caspase 3 和 9 的表达。
T2823 Crocin

西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素

Others Others
Crocin (Gardenia Yellow) 是从Crocus sativus 柱头中分离出的主要成分,是一种营养保健品,具有抗炎,抗癌,抗抑郁和抗惊厥等强大的药理作用。
T6S0653 Linarin

Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷

TNF; AChE Apoptosis; Neuroscience
Linarin (Acacetin-7-O-rutinoside) 是一种选择性的乙酰胆碱酯酶 (AChE) 抑制剂,从薄荷花提取物中分离得到。
T6S0735 Flavokawain B

黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone

Apoptosis; Others Apoptosis; Others
Flavokawain B (Flavokavain B) 是从卡瓦醉椒的根提取物中,分离出的查尔酮。它是一种凋亡诱导剂,可抑制各种癌细胞株生长。它以极低的无毒浓度抑制人脑内皮细胞的迁移和血管形成,具有抗血管生成活性。
T3729 Ethyl gallate

Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯

MMP; NF-κB; Akt; Antibacterial Cytoskeletal Signaling; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Ethyl gallate (gallic acid ethyl ester) 是一种非类黄酮酚过氧化氢清除剂。
T3895 Polyphyllin I

重楼皂苷I,重楼皂甙

Apoptosis; Akt; JNK; PDK; mTOR; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Polyphyllin I 是从七叶一枝花中提取的生物活性成分,具有很强的抗肿瘤活性。它是 JNK 信号通路的激活剂,也是 PDK1/Akt/mTOR 信号传导的抑制剂。它诱导自噬,G2/M 期阻滞和细胞凋亡。
T3923 Calycosin

Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮

Apoptosis; Tyrosinase Apoptosis; Proteases/Proteasome
Calycosin (Cyclosin) 是一抗氧化和抗炎症活性天然产物。
T2966 Beta-Sitosterol

Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost

Apoptosis; Lipase; Endogenous Metabolite Apoptosis; Metabolism
Beta-Sitosterol (SKF 14463) 是一种植物甾醇,干扰细胞周期、细胞凋亡、增殖、存活、侵袭、血管生成和炎症等多种细胞信号通路。
T3864 Erianin

BCL; Antibacterial Apoptosis; Microbiology/Virology
Erianin 能抑制吲哚胺-2,3-双加氧酶诱导的肿瘤血管生成,可用作退烧药和止疼剂。
T2698 Asperosaponin VI

Akebia saponin D,Asperosaponin Ⅵ,川续断皂苷 VI

Apoptosis; Others; Caspase Apoptosis; Others; Proteases/Proteasome
Asperosaponin VI (Akebia saponin D) 是一种来自续断壁的皂苷组分。它通过增加 Bcl-2/Bax 比值,降低活性 caspase-3 表达,以及增强 p-Akt 和 p-CREB,从而抑制缺氧诱导的心肌细胞凋亡。它通过 BMP-2/p38 和 ERK1/2 信号途径诱导成骨细胞分化。
T0186 Docetaxel trihydrate

RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate,多西他赛三水合物

Apoptosis; BCL; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Docetaxel trihydrate (RP-56976 Trihydrate) 是一种抗肿瘤试剂,抑制微管解聚的IC50值为 0.2 μM。它是紫杉醇的半合成类似物,能减弱 bcl-2bcl-xL 基因表达的影响。它阻滞G2/M 细胞周期,导致细胞凋亡。
T5S0661 Koumine

Others Others
Koumine 是一种从钩吻中得到的生物碱,具有高效抗肿瘤活性,在肿瘤细胞中能够提高 Bax/Bcl-2 的蛋白比例和 caspase-3 的表达。在类风湿性关节炎动物模型中,它能够预防关节炎的发展。它具有抗焦虑、抗应激、抗银屑病作用,也可用于缓解疼痛的研究。
TN3653 Cimidahurinine

BCL; ROS Apoptosis; Immunology/Inflammation
Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity by decreasing reactive oxygen species (ROS) accumulation and downregulating apoptosis-related Bax/Bcl-2 proteins.
T81229 Safflor yellow B

Safflor yellow B 通过抑制血管紧张素 II 介导的人脐静脉细胞损伤,调节 Bcl-2/p22 (phox) 表达,展现出神经保护作用。
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天然产物

Jaceosidin
Cat.No: T3824
Synonym:
Target: Apoptosis, BCL, COX, UGT
Dihydrokaempferol
Cat.No: TN1406
Synonym: 香橙素,Aromadendrin
Target: Apoptosis, BCL
Isolinderalactone
Cat.No: T8213
Synonym:
Target: NOS, STAT
Epieriocalyxin A
Cat.No: TN3967
Synonym:
Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK
2-Hydroxychalcone
Cat.No: T7979
Synonym: 2-(2-Hydroxybenzal)Acetophenone,2-羟基查酮
Target: Apoptosis, BCL, Others, NF-κB
Gossypol
Cat.No: T6518
Synonym: Pogosin,BL 193,棉酚,NSC 56817
Target: BCL, Dehydrogenase
Chelerythrine
Cat.No: T6S0052
Synonym: Toddalin,Broussonpapyrine,白屈菜红碱,Cheleritrine
Target: Apoptosis, BCL, PKC, Autophagy
Albiflorin
Cat.No: T6S1653
Synonym: Alibiflorin,芍药内酯苷
Target: Reactive Oxygen Species
Chelerythrine chloride
Cat.No: T3419
Synonym: 白屈菜红碱,盐酸白屈菜红碱
Target: Apoptosis, BCL, PKC, Autophagy
Dehydrocorydaline
Cat.No: T5S2358
Synonym: Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Ilexsaponin A
Cat.No: T2S0500
Synonym: 毛冬青皂苷A,毛冬青皂苷甲,Ilexsaponin A1
Target: Others
Dehydrocorydaline chloride
Cat.No: T10990
Synonym: 盐酸脱氢紫堇碱,13-Methylpalmatine chloride
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Gambogic Acid
Cat.No: T6185
Synonym: 藤黄酸,Beta-Guttiferrin,藤黄酸 A,Guttatic Acid,Guttic Acid
Target: BCL, Autophagy
Dehydrocorydaline nitrate
Cat.No: T2S2362
Synonym: 去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱
Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy
(E)-Ferulic acid
Cat.No: T5679
Synonym: trans-Ferulic acid,反式阿魏酸,(E)-Coniferic acid
Target: BCL, Ferroptosis, Wnt/beta-catenin, Endogenous Metabolite
(S)-10-Hydroxycamptothecin
Cat.No: T2764
Synonym: 10-羟喜树碱,10-羟基喜树碱,10-Hydroxycamptothecin,10-HCPT
Target: Apoptosis, Topoisomerase
trans-Chalcone
Cat.No: T3322
Synonym: Chalcone,反-查耳酮,查尔酮,Cinnamophenone,Chalkone
Target: Apoptosis, Others, Antifungal, Fatty Acid Synthase
Ciwujianoside B
Cat.No: T3344
Synonym: yemuoside YM,刺五加皂苷 B,acanthopanax senticosides B,刺五加皂甙 B,Ciwujianoside-B
Target: BCL, Others
Gossypol (acetic acid)
Cat.No: T2730
Synonym: (±)-Gossypol-acetic acid,Pogosin,AT101,醋酸棉酚,乙酸棉子酚,Gossypol acetic acid
Target: BCL
Dihydrocapsaicin
Cat.No: T2163
Synonym: CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
Target: Others, TRP/TRPV Channel
Daphnetin
Cat.No: T2851
Synonym: 7,8-Dihydroxycoumarin,Daphnetol,瑞香素
Target: EGFR, PKA, PKC, Parasite, Autophagy
Paris saponin VII
Cat.No: T4085
Synonym: 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII
Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy
Amantadine
Cat.No: T7060
Synonym: 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine
Target: Others
Schisandrol B
Cat.No: T6S1917
Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B
Target: P450, Reactive Oxygen Species, Autophagy
Docetaxel
Cat.No: T1034
Synonym: 多西他赛,NSC 628503,RP-56976,多烯紫杉醇
Target: Apoptosis, Microtubule Associated, Endogenous Metabolite
magnolin
Cat.No: T3857
Synonym: 木兰脂素,(+)-Magnolin,木兰苷
Target: ERK
Cynarin
Cat.No: T6S1529
Synonym: Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1R,​3R,​4S,​5R)​-,Cynarine,1,5-Dicaffeoylquinic acid,洋蓟素,金银花
Target: Antioxidant, Antiviral, Influenza Virus, Reactive Oxygen Species
Euphorbia factor L1
Cat.No: T2S0410
Synonym: Euphorbiasteroid,大戟因子L1,大戟因子 L1
Target: Apoptosis, P-gp
Puerarin 6''-O-Xyloside
Cat.No: T5S2083
Synonym:
Target: Apoptosis, Caspase
Alpinetin
Cat.No: T3867
Synonym: 山姜素,(-)-alpinetin
Target: BCL, PPAR
EURYCOMANONE
Cat.No: T7027
Synonym: 东革阿里提取物,Pasakbumin A
Target: Others
Amygdalin
Cat.No: T2795
Synonym: 苦杏仁苷,Laetrile
Target: Others
Praeruptorin C
Cat.No: T6S1418
Synonym:
Target: Antioxidant, Calcium Channel
Taccalonolide A
Cat.No: TN2254
Synonym: 根薯酮内酯A,根薯酮内酯 A
Target: Apoptosis, Microtubule Associated
β,β-Dimethylacrylshikonin
Cat.No: T3S2344
Synonym: β,β-二甲基丙烯酰紫草素,Dimethylacrylshikonin,β, β-Dimethylacrylshikonin
Target: ERK, HIF/HIF Prolyl-Hydroxylase
Vanillyl Alcohol
Cat.No: T2860
Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol
Target: Apoptosis, Others
PROCYANIDIN C1
Cat.No: TN2103
Synonym: 原花青素 C1,原花青素C1
Target: Apoptosis
Crocin
Cat.No: T2823
Synonym: 西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素
Target: Others
Linarin
Cat.No: T6S0653
Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷
Target: TNF, AChE
Flavokawain B
Cat.No: T6S0735
Synonym: 黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone
Target: Apoptosis, Others
Ethyl gallate
Cat.No: T3729
Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯
Target: MMP, NF-κB, Akt, Antibacterial
Polyphyllin I
Cat.No: T3895
Synonym: 重楼皂苷I,重楼皂甙
Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy
Calycosin
Cat.No: T3923
Synonym: Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮
Target: Apoptosis, Tyrosinase
Beta-Sitosterol
Cat.No: T2966
Synonym: Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost
Target: Apoptosis, Lipase, Endogenous Metabolite
Erianin
Cat.No: T3864
Synonym:
Target: BCL, Antibacterial
Asperosaponin VI
Cat.No: T2698
Synonym: Akebia saponin D,Asperosaponin Ⅵ,川续断皂苷 VI
Target: Apoptosis, Others, Caspase
Docetaxel trihydrate
Cat.No: T0186
Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate,多西他赛三水合物
Target: Apoptosis, BCL, Microtubule Associated
Koumine
Cat.No: T5S0661
Synonym:
Target: Others
Cimidahurinine
Cat.No: TN3653
Synonym:
Target: BCL, ROS
Safflor yellow B
Cat.No: T81229
Synonym:
Target:
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Cat. No. Product Name Species Expression System
TMPY-02700 BCL2 Protein, Human, Recombinant (His)

Bcl-2,PPP1R50,B-cell CLL/lymphoma 2

Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins...
TMPJ-00717 BAG2 Protein, Human, Recombinant (His)

BAG-2,BAG Family Molecular Chaperone Regulator ...

Human E. coli
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
TMPH-02520 BCL2 Protein, Mouse, Recombinant (His)

Bcl2,Apoptosis regulator Bcl-...

Mouse E. coli
BCL2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.7 kDa and the accession number is P10417.
TMPH-03245 BCL2 Protein, Rat, Recombinant (His)

Bcl2,Apoptosis regulator Bcl-...

Rat E. coli
BCL2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 28.1 kDa and the accession number is P49950.
TMPJ-00584 Bc1-w Protein, Human, Recombinant (His)

Apoptosis Regulator Bcl-W,KIAA0271,Bcl...

Human E. coli
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone...
TMPY-02004 BCL-W Protein, Human, Recombinant (His)

BCL2-L-2,BCL-W,BCL

Human E. coli
BCL-W Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20 kDa and the accession number is Q92843-1.
TMPH-02534 BAG3 Protein, Mouse, Recombinant (His)

Bcl-2-associated athanogene 3,Bag3,Bcl...

Mouse P. pastoris (Yeast)
BAG3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is Q9JLV1.
TMPH-02535 BAG3 Protein, Mouse, Recombinant (His & SUMO)

Bcl-2-associated athanogene 3,Bis,BAG-3,BA...

Mouse E. coli
BAG3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 77.7 kDa and the accession number is Q9JLV1.
TMPJ-00038 IL-7 Protein, Mouse, Recombinant (His)

interleukin-7,白介素,IL-7,IL-7 interleukin-7,PBGF,Lymphopoietin...

Mouse HEK293 Cells
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell...
TMPY-03974 Bim Protein, Human, Recombinant (His)

BAM,BCL2-like 11 (apoptosis facilitator),B...

Human E. coli
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L11 contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. BCL2L11 gene functions as an essential initiator of apoptosis in thymoc...
TMPK-00636 BID Protein, Mouse, Recombinant (His)

BID,p22 BID

Mouse E. coli
Bid, BH3-interacting domain death agonist, was initially cloned based in its ability to interact with both Bcl-2 and Bax. Bid contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. Bid is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. Bid is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals.
TMPH-00535 Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)

EBV E. coli
Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell.
TMPY-02001 RTN4 Protein, Human, Recombinant (GST)

UNG1,NOGO,reticulon 4,RTN4-A,Nbla00271,NOGO-A,RTN-X...

Human E. coli
Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that contains one reticulon domain. Isoform 1 of RTN4 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 of RTN4 is widely expressed except for the liver. Isoform 3 of RTN4 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 ...
TMPY-04768 PRPS2 Protein, Human, Recombinant (His)

PRPS2,PRSII,phosphoribosyl pyrophosphate synthetase...

Human E. coli
PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine...
TMPJ-00455 SLAMF5 Protein, Mouse, Recombinant (His)

CD84 molecule,SLAM family member 5,Leukocyte differentiation...

Mouse HEK293 Cells
CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based switch motifs (ITSM) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. CD84 expression has been documented on several hemato...
TMPJ-01066 CYCS Protein, Human, Recombinant (His)

CYC,Cytochrome C,CYCS

Human E. coli
Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as a central component of the electron transport chain in mitochondria. CYCS transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase). CYCS plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic...
TMPY-04936 BCL2A1 Protein, Human, Recombinant (His)

BFL1,ACC1,ACC-2,GRS,ACC-1,HBPA1,BCL2

Human E. coli
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. Bcl2 family proteins control mitochondrial apoptosis and its members exert critical cell type and differentiation stage-specific functions, acting as barriers against autoimmunity or transformation. Anti-apoptotic Bcl2a1/Bfl1/A1 is frequently der...
TMPJ-00681 EDIL3 Protein, Human, Recombinant (His)

EGF-Like Repeats and Discoidin I-Like Domains 3,EDIL3

Human HEK293 Cells
EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at the time of birth, and is no longer expressed in normal adult tissues. EDIL3 has been found to be re-expressed in a number of human tumors as well as in ischemic muscles and ischemic brain tissue, which may play an important role in adult angiogenesis. EDIL3 promotes adherence a...
TMPY-04417 DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)

DAPK,death-associated protein kinase 1,ROCO3

Human Baculovirus Insect Cells
Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK1 contains tenANK repeats, onedeath domain and oneprotein kinase domain. DAPK1 is a calcium / calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. DAPK1 gene is a candidate tumor suppressor (TSG) and the abnormal methylation of DAPK1 g...
TMPY-01824 Caspase-14 Protein, Human, Recombinant (His)

caspase 14, apoptosis-related cysteine peptidase,ARCI12<...

Human E. coli
Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Casp...
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Protein T1,suppression of tumorigenicity 2,Ly84,DER...

Mouse HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02011 CD96 Protein, Human, Recombinant (His)

CD96 molecule,TACTILE

Human HEK293 Cells
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...

Human E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His)

A630052E07Rik,OSF-2,Osf2,PLF,AI74...

Mouse HEK293 Cells
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPY-01717 VEGF164 Protein, Mouse, Recombinant

vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子

Mouse Baculovirus Insect Cells
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-02096 TACI Protein, Human, Recombinant (His)

RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...

Human HEK293 Cells
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-03795 EIF5A2 Protein, Human, Recombinant (His)

eIF5AII,eukaryotic translation initiation factor 5A2

Human E. coli
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted in the downregulation of the tumorigenic proteins, apoptosis regulator Bcl-2 and myc proto-oncogene protein, and upregulation of E-cadherin, suggesting that EIF5A2 promotes proliferation and metastasis through these proteins. EIF5A2 may therefore serve as a novel therapeutic targe...
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His)

KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL...

Human E. coli
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-00751 TrkB Protein, Human, Recombinant (His)

trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...

Human HEK293 Cells
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His)

SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP...

Human HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-04844 BTN3A1 Protein, Human, Recombinant (His)

BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2...

Human HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-05288 PLGF/PGF Protein, Human, Recombinant (aa 19-149)

PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...

Human E. coli
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-02820 SDF-1 Protein, Human, Recombinant (isoform a)

SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1

Human E. coli
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-01935 c-Kit Protein, Human, Recombinant (His)

PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-04356 GSK3B Protein, Human, Recombinant (His)

glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β

Human Baculovirus Insect Cells
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02500 YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

Gp39,AW208766,Brp39,chitinase 3 like 1

Mouse HEK293 Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01985 CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

FCGR2,FCGR21,CD32A,FCG2,...

Human HEK293 Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04644 PDGFB Protein, Human, Recombinant (His)

platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...

Human P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-05414 NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

D6H12S2489E,NKG2-D,killer cell le...

Mouse Baculovirus Insect Cells
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-01871 IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

interleukin 5 receptor, alpha,IL5R,CD125,CDw12<...

Human HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293)

HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...

Human HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His)

KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...

Human E. coli
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-01359 ST2/IL-1 RL1 Protein, Human, Recombinant (His)

IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-00747 Nectin-2 Protein, Human, Recombinant (His)

PVRR2,Nectin-2,poliovirus receptor-related...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-05427 CD19 Protein, Human, Recombinant (hFc)

CVID3,B4,CD19 molecule

Human HEK293 Cells
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His)

TGFR-2,TGF-beta type II receptor,Transforming growt...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
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重组蛋白

BCL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02700
Species: Human
Expression System: E. coli
BAG2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00717
Species: Human
Expression System: E. coli
BCL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02520
Species: Mouse
Expression System: E. coli
BCL2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03245
Species: Rat
Expression System: E. coli
Bc1-w Protein, Human, Recombinant (His)
Cat.No: TMPJ-00584
Species: Human
Expression System: E. coli
BCL-W Protein, Human, Recombinant (His)
Cat.No: TMPY-02004
Species: Human
Expression System: E. coli
BAG3 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02534
Species: Mouse
Expression System: P. pastoris (Yeast)
BAG3 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02535
Species: Mouse
Expression System: E. coli
IL-7 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00038
Species: Mouse
Expression System: HEK293 Cells
Bim Protein, Human, Recombinant (His)
Cat.No: TMPY-03974
Species: Human
Expression System: E. coli
BID Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00636
Species: Mouse
Expression System: E. coli
Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)
Cat.No: TMPH-00535
Species: EBV
Expression System: E. coli
RTN4 Protein, Human, Recombinant (GST)
Cat.No: TMPY-02001
Species: Human
Expression System: E. coli
PRPS2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04768
Species: Human
Expression System: E. coli
SLAMF5 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00455
Species: Mouse
Expression System: HEK293 Cells
CYCS Protein, Human, Recombinant (His)
Cat.No: TMPJ-01066
Species: Human
Expression System: E. coli
BCL2A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04936
Species: Human
Expression System: E. coli
EDIL3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00681
Species: Human
Expression System: HEK293 Cells
DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)
Cat.No: TMPY-04417
Species: Human
Expression System: Baculovirus Insect Cells
Caspase-14 Protein, Human, Recombinant (His)
Cat.No: TMPY-01824
Species: Human
Expression System: E. coli
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Cat.No: TMPJ-00850
Species: Mouse
Expression System: HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
Cat.No: TMPY-00891
Species: Human
Expression System: HEK293 Cells
CD96 Protein, Human, Recombinant (His)
Cat.No: TMPY-02011
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Cat.No: TMPY-04113
Species: Human
Expression System: E. coli
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01613
Species: Mouse
Expression System: HEK293 Cells
VEGF164 Protein, Mouse, Recombinant
Cat.No: TMPY-01717
Species: Mouse
Expression System: Baculovirus Insect Cells
TACI Protein, Human, Recombinant (His)
Cat.No: TMPY-02096
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
Cat.No: TMPY-00341
Species: Human
Expression System: HEK293 Cells
EIF5A2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03795
Species: Human
Expression System: E. coli
KRAS Protein, Human, Recombinant (G12D, His)
Cat.No: TMPY-06056
Species: Human
Expression System: E. coli
TrkB Protein, Human, Recombinant (His)
Cat.No: TMPY-00751
Species: Human
Expression System: HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His)
Cat.No: TMPY-01691
Species: Human
Expression System: HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04844
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
Cat.No: TMPY-05288
Species: Human
Expression System: E. coli
SDF-1 Protein, Human, Recombinant (isoform a)
Cat.No: TMPY-02820
Species: Human
Expression System: E. coli
c-Kit Protein, Human, Recombinant (His)
Cat.No: TMPY-01935
Species: Human
Expression System: HEK293 Cells
GSK3B Protein, Human, Recombinant (His)
Cat.No: TMPY-04356
Species: Human
Expression System: Baculovirus Insect Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02500
Species: Mouse
Expression System: HEK293 Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-01985
Species: Human
Expression System: HEK293 Cells
PDGFB Protein, Human, Recombinant (His)
Cat.No: TMPY-04644
Species: Human
Expression System: P. pastoris (Yeast)
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05414
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
Cat.No: TMPY-01871
Species: Human
Expression System: HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-02792
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human, Recombinant (Q61H, His)
Cat.No: TMPY-01888
Species: Human
Expression System: E. coli
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01359
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00747
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05427
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00335
Species: Mouse
Expression System: HEK293 Cells
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