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Anti-BCL-XL Antibody (1J99)

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Anti-BCL-XL Antibody (1J99)
产品编号 TMAH-00110
别名 PPP1R52, bcl-xS, BCLXS, BCL-XL/S, bcl-xL, BCLXL, Bcl-X, BCLX, BCL2-like 1, BCL2L

Anti-BCL-XL Antibody (1J99) 是一种 Mouse 抗体,靶向 BCL-XL。Anti-BCL-XL Antibody (1J99) 可用于 ELISA, WB, IHC。

Anti-BCL-XL Antibody (1J99)

Anti-BCL-XL Antibody (1J99)

Rating icon 还可以
Anti-BCL-XL Antibody (1J99)
产品编号 TMAH-00110 别名 PPP1R52, bcl-xS, BCLXS, BCL-XL/S, bcl-xL, BCLXL, Bcl-X, BCLX, BCL2-like 1, BCL2L

Anti-BCL-XL Antibody (1J99) 是一种 Mouse 抗体,靶向 BCL-XL。Anti-BCL-XL Antibody (1J99) 可用于 ELISA, WB, IHC。

规格价格库存数量
50 μg
¥ 1,310
5日内发货
100 μg
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-BCL-XL Antibody (1J99) is a Mouse antibody targeting BCL-XL. Anti-BCL-XL Antibody (1J99) can be used in ELISA, WB, IHC.
别名PPP1R52, bcl-xS, BCLXS, BCL-XL/S, bcl-xL, BCLXL, Bcl-X, BCLX, BCL2-like 1, BCL2L
Ig Type
IgG1
克隆号
1J99
交叉反应
Human
验证活性
1. Immunohistochemical of paraffin-embedded Human endometrium tissue using TMAH-00110 at dilution of 1:200
2. Immunohistochemical of paraffin-embedded Human Colon cancer tissue using TMAH-00110 at dilution of 1:200
3. Western Blot
-All lanes:Mouse anti BCL2L1 Monoclonal antibody at 1μg/ml
-Lane 1:HepG2 whole cell lysate
-Secondary Goat polyclonal to Mouse IgG at 1/5000 dilution
-Predicted band size:26,27,19kd
-Observed band size:26KD
应用
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位[Isoform Bcl-X(L)]: Mitochondrion inner membrane. Mitochondrion outer membrane. Mitochondrion matrix. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
纯度>95%
研究背景Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release. Isoform Bcl-X(S) promotes apoptosis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human Bcl-2-like Protein 1 Protein
抗原种属
Human
基因ID
Uniprot ID
研究领域
Cell Biology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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