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Anti-BCL-XL Antibody (1J99) 是一种 Mouse 抗体,靶向 BCL-XL。Anti-BCL-XL Antibody (1J99) 可用于 ELISA, WB, IHC。
Anti-BCL-XL Antibody (1J99) 是一种 Mouse 抗体,靶向 BCL-XL。Anti-BCL-XL Antibody (1J99) 可用于 ELISA, WB, IHC。
产品描述 | Anti-BCL-XL Antibody (1J99) is a Mouse antibody targeting BCL-XL. Anti-BCL-XL Antibody (1J99) can be used in ELISA, WB, IHC. |
别名 | PPP1R52, bcl-xS, BCLXS, BCL-XL/S, bcl-xL, BCLXL, Bcl-X, BCLX, BCL2-like 1, BCL2L |
Ig Type | IgG1 |
克隆号 | 1J99 |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical of paraffin-embedded Human endometrium tissue using TMAH-00110 at dilution of 1:200 2. Immunohistochemical of paraffin-embedded Human Colon cancer tissue using TMAH-00110 at dilution of 1:200 3. Western Blot -All lanes:Mouse anti BCL2L1 Monoclonal antibody at 1μg/ml -Lane 1:HepG2 whole cell lysate -Secondary Goat polyclonal to Mouse IgG at 1/5000 dilution -Predicted band size:26,27,19kd -Observed band size:26KD |
应用 | ELISA, WB, IHC |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
亚细胞定位 | [Isoform Bcl-X(L)]: Mitochondrion inner membrane. Mitochondrion outer membrane. Mitochondrion matrix. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Protein G purified |
性状 | Liquid |
缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
纯度 | >95% |
研究背景 | Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.; Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP av... |
偶联 | Unconjugated |
免疫原 | Recombinant Human Bcl-2-like protein 1 protein |
抗原种属 | Human |
基因ID | 598 |
Uniprot ID | |
研究领域 | Cell Biology |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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