购物车
- 全部删除
您的购物车当前为空
Anti-Mcl-1 Antibody (4I237)
还可以产品编号 TMAY-00215
别名 TM, MCL1S, MCL1L, MCL1-ES, mcl1/EAT, Mcl-1, EAT, bcl2-L-3, BCL2L3
Anti-Mcl-1 Antibody (4I237) 是一种 Mouse 抗体，靶向 Mcl-1。Anti-Mcl-1 Antibody (4I237) 可用于 IHC-P。
Anti-Mcl-1 Antibody (4I237)
Anti-Mcl-1 Antibody (4I237)
还可以产品编号 TMAY-00215 别名 TM, MCL1S, MCL1L, MCL1-ES, mcl1/EAT, Mcl-1, EAT, bcl2-L-3, BCL2L3
Anti-Mcl-1 Antibody (4I237) 是一种 Mouse 抗体，靶向 Mcl-1。Anti-Mcl-1 Antibody (4I237) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,679 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Mcl-1 Antibody (4I237) is a Mouse antibody targeting Mcl-1. Anti-Mcl-1 Antibody (4I237) can be used in IHC-P. |
| 别名 | TM, MCL1S, MCL1L, MCL1-ES, mcl1/EAT, Mcl-1, EAT, bcl2-L-3, BCL2L3 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4I237 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human MCL1 in human breast carcinoma with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:20-1:80 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the center region of the Human Mcl-1. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | MCL1 is an anti-apoptotic protein in the BCL2 family and amplifies frequently in multiple human cancers. Myeloid cell leukemia sequence 1 (MCL1) is a potent anti-apoptotic protein that plays a critical role in cell survival and drug resistance in various cancers. MCL1 is a pivotal member of the anti-apoptotic BCL-2 family proteins. While a distinctive feature of MCL1 resides in its efficient ubiquitination and destruction, the deubiquitinase USP9X has been implicated in the preservation of MCL1 expression by removing the polyubiquitin chains.MCL1 is also known as a potential contributor to the resistance of BCL2 inhibitors, as well as various chemotherapeutic drugs. MCL1 is, therefore, regarded as a potential target for cancer therapy. The overexpression of MCL1 promotes cell survival and confers chemotherapeutic resistance. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the center region of the Human Mcl-1 |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-Mcl-1 Antibody (4I237) | purchase Anti-Mcl-1 Antibody (4I237) | Anti-Mcl-1 Antibody (4I237) cost | order Anti-Mcl-1 Antibody (4I237)
嗨！有任何问题？点我咨询
评论内容