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1608

抑制剂 & 化合物

61

天然产物

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Cat. No. Product Name Target Signaling Pathways
T21606L Anti-Inflammatory Peptide 1 Acetate

Anti-Inflammatory Peptide 1 Acetate(118850-70-8 Free base)

Phospholipase Metabolism
Anti-Inflammatory Peptide 1 Acetate 在体内具有有效的抗炎活性,是磷脂酶 A2 (PLA2) 的强抑制剂,其存在和活性增加会导致某些身体部位的炎症和疼痛。
TP1359L Amyloid β Peptide (42-1)(human) acetate

Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Beta Amyloid Neuroscience
Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽,其在阿尔茨海默病的发病机制中起关键作用。
T21649L GnRH Associated Peptide (GAP) (1-13), human Acetate

GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base)

Others Others
GnRH Associated Peptide (GAP) (1-13), human Acetate 被发现是催乳素分泌的有效抑制剂并刺激促性腺激素的释放。用对应于 GAP 序列的肽进行主动免疫导致催乳素分泌大大增加。
T39392L C-Type Natriuretic Peptide (CNP) (1-22), human acetate

C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)

Others Others
C-Type Natriuretic Peptide (CNP) (1-22), human acetate 是一种利钠肽受体 B (NPR-B) 的激动剂,一种内皮衍生的松弛剂和生长抑制因子。 C-Type Natriuretic Peptide (CNP) (1-22), human acetate 抑制由组胺和 5-HT 或直接由毛喉素刺激的 cAMP 合成。
TP1219 Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

ANP (1-28), human, porcineANP(1-28)

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 是颗粒鸟苷酸环化酶的刺激剂,已被发现通过增加环鸟苷单磷酸的合成来保护分离的心肌细胞免受复氧诱导的高收缩。Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 也有助于在反复运动期间刺激脂解,并在运动期间控制脂解。
TP1187 C-Type Natriuretic Peptide (CNP) (1-22), human

CNP (1-22), human

RAAS Endocrinology/Hormones
C-Type Natriuretic Peptide (CNP) (1-22), human 是一种利钠肽受体 B (NPR-B) 激动剂,是一种 CNP 的 1-22 片段。它对生理激动剂组胺和 5-HT 刺激或直接由 Forskolin 刺激的 cAMP 合成具有抑制作用。其中CNP 是一种有效的、内皮衍生的松弛剂和生长抑制因子。
TP1033L Transdermal Peptide Disulfide Acetate

TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base)

ATPase Membrane transporter/Ion channel
Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) 是一种 11 个氨基酸的肽,与 Na+/K+-ATPase β 亚基 (ATP1B1) 结合,主要与 ATP1B1 的 C 端相互作用。透皮肽可以增强许多大分子的透皮传递。透皮肽 TD 1 酰胺是一种新型肽,旨在增强透皮药物传递。
TP1526L1 Fibronectin CS1 Peptide acetate

Others Others
Fibronectin CS1 Peptide acetate 存在于 III 型同源连接段 (IIICS) 以及 C-274(细胞结合结构域)中。 Fibronectin CS1 Peptide 缺乏含有 Arg-Gly-Asp 的结构域,在自发和实验性转移模型中积极抑制肿瘤转移。
T37766 Transdermal Peptide (TD 1 (peptide))

Transdermal Peptide is a 11-amino acid peptide, binds to Na+/K+-ATPase beta-subunit (ATP1B1), and enhances the transdermal delivery of many macromolecules. Transdermal Peptide (TD1) binds to ATP1B1, and mainly interacts with the C-terminus of ATP1B1 in yeast and mammalian cells. The interaction affects the expression and localization of ATP1B1 and epidermal structure, but can be antagonized by the exogenous competitor ATP1B1 or be inhibited by ouabain. Inhibition of Transdermal Peptide binding t...
TP2411 Sperm-activating peptide 1

Sperm-activating peptide 1 is a bioactive chemical.
T7625 TRAP-6

PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)

Protease-activated Receptor GPCR/G Protein
TRAP-6 (Thrombin Receptor Activator Peptide 6) 是一种多肽片段,是选择性的蛋白酶激活受体 1 (PAR1) 激动剂,通过凝血酶受体激活人血小板。
T39178 Tyrosine Kinase Peptide 1

Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay.
TP1497L Mast Cell Degranulating Peptide HR-2 acetate

Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base)

Others Others
Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base) 来自大黄蜂 Vespa orientalis 的肥大细胞脱粒肽,其生物学效应类似于来自蜂毒的肥大细胞脱粒肽。
TP1710 Calmodulin Binding Peptide 1

Calmodulin Binding Peptide 1, a potent CaM-binding peptide with picomolar (pM) affinity, originates from smooth muscle myosin light-chain kinase (MLCK peptide). It effectively blocks inositol trisphosphate (IP3)-induced calcium (Ca2+) release [1].
TP1754 Bombinin-Like Peptide (BLP-1)

Bombinin-Like Peptide BLP-1

Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide from Bombina species.
TP1015 NFAT Inhibitor

VIVIT peptide

Others Others
NFAT Inhibitor (VIVIT peptide) 是NFAT 的细胞渗透性肽抑制剂,能够选择性抑制钙调磷酸酶介导的NFAT 脱磷酸作用。
TP1148 Glucagon-like peptide 1 (1-37), human

HuGLP-1

Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.Pancreatic hormone synthesized by post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on food intake in rats and does not en
TP1117 IFN-α Receptor Recognition Peptide 1

IRRP1

IFN-α Receptor Recognition Peptide 1 is a peptide of IFN-α associated with receptor interactions.
TP1148L Glucagon-like peptide 1 (1-37), human acetate

Glucagon Receptor GPCR/G Protein
Glucagon-like peptide 1 (1-37), human acetate 是一种高效的 GLP-1 受体激动剂。
TP1756 Brain Natriuretic Peptide (1-32), rat

Brain Natriuretic Peptide (BNP) (1-32), rat

Brain Natriuretic Peptide (BNP) (1-32), rat is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).Brain natriuretic peptide (type B natriuretic peptide) was origin
TP1833L SLLK, Control Peptide for TSP1 Inhibitor acetate

SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base)

Others Others
SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base) 是 LSKL 的对照肽。
T37369 Amyloid-β (1-8, A2V) Peptide

Amyloid-β (1-8, A2V) Peptide

Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor protein (APP) numbering convention (APP A673V). An Aβ (1-40) (Aβ40) A2V peptide increases the production of Aβ and the rate and amount of amyloid fibril formation in vitro, effects that can be reduced by coincubation with wild-type Aβ40. Aβ40 and Aβ42 levels are increased in CHO ...
T37368 Amyloid-β (1-8) Peptide

Amyloid-β (1-8) is a wild-type control for the mutation-containing amyloid-β (1-8, A2V) peptide .
TP1809 TAT

HIV Protease Microbiology/Virology; Proteases/Proteasome
TAT 源自人免疫缺陷病毒的转录反式激活因子,是一种细胞穿透肽。它可以增加异源蛋白质的产量和溶解度。
TP1147 Glucagon-like peptide 1 (1-37), human TFA

HuGLP-1 TFA

Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor, it is a kind of pancreatic hormone synthesized by post-translational processing of proglucagon.
T21825 TAE-1

Beta Amyloid; AChE Neuroscience
TAE-1 是淀粉样蛋白-β 原纤维形成和聚集的抑制剂。它抑制胆碱酯酶 AChE 和 BuChE,IC50 分别为 0.3 μM 和 3.9 μM。
TP1769 Prolactin Releasing Peptide (1-31), human

Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin. Human and rat Prolactin Releasing Peptide (1-31) binds to GPR10 with Kis of 1.03 and 0.33 nM, respectively.Prolactin-releasing peptide is a
TP1311 RGD peptide (GRGDNP) (TFA) (114681-65-1 free base)

RGD peptide (GRGDNP) (TFA)

RGD peptide (GRGDNP) (TFA) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing.
T37367 Amyloid-β (1-42) Peptide (trifluoroacetate salt)

Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease.1,2,3Aggregation of Aβ42 results in the formation of neurotoxic fibrils or globular oligomers.1Aβ42 accumulates in the brain of many transgenic mouse models of Alzheimer's disease and, in many models, the onset of amyloid deposition positively correlates with deficits in spatial learning and memory.4 1.Wolfe, M.S.Therapeutic strategi...
TP1581 C-Type Natriuretic Peptide (1-53), human

CNP, a member of the natriuretic peptide family, was first identified in porcine brain and later found in other mammals as well as non-mammals. Processing of the CNP precursor gives rise to CNP-22 and its N-terminally elongated form, CNP-53. The CNPs shar
T37200 Biotin-Amyloid-β (1-42) Peptide (trifluoroacetate salt)

Biotin-amyloid-β (1-42) peptide is an affinity probe that allows amyloid-β (1-42) (Aβ42) to be detected or immobilized through interaction with the biotin ligand. It has been used to identify Aβ42 interaction partners in rat hippocampal synaptosomal membranes.
T35832 Brain Natriuretic Peptide (1-32), rat acetate

Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide hormone synthesized by ventricular cardiomyocytes as a result of myocardial cell stretching (cardiomyocyte distension)[1].
TP1221 Atrial Natriuretic Peptide (ANP) (1-28), rat

Atrial natriuretic factor (1-28) (rat)

Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
T37472 TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt)

TAMRA-Amyloid-β (1-42) peptide is a fluorescently labeled peptide. Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-residue protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease. Aggregation of Aβ42 results in the formation of neurotoxic fibrils or globular oligomers. TAMRA-Amyloid-β (1-42) peptide is a labeled form of Aβ42 containing carboxytetramethyl rhodamine (TAMRA), which displays excitation/emission maxima of 543/572 nm, respectively.
T3259 FPS-ZM1

Beta Amyloid; advanced glycation end products Neuroscience; Others
FPS-ZM1 是一种高亲和力的 RAGE 特异性抑制剂,可阻断 Aβ 与 RAGE 的 V 结构域的结合。
T39244 Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, is one of three mammalian natriuretic peptides (NPs) that exerts endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide holds promise for cardiovascular diseases research.
T5519 Bivalirudin

BG-8967,比伐卢定,Hirulog-1

Thrombin Proteases/Proteasome
Bivalirudin (BG-8967) 是一种直接凝血酶(thrombin)抑制剂,是一种肽类抗凝剂,可在侵入性心脏病,特别是在经皮冠状动脉介入中用于抗凝。
T39392 C-Type Natriuretic Peptide (CNP) (1-22), human TFA

C-Type Natriuretic Peptide (CNP) (1-22), human (TFA), is a 22 amino acid fragment of CNP and functions as an agonist for the natriuretic peptide receptor B (NPR-B). It can inhibit cAMP synthesis, which is induced by histamine, 5-HT, or Forskolin. Additionally, CNP exhibits strong endothelial-derived relaxation properties and acts as a growth inhibitor.
TP1220L Carperitide acetate

醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

Endothelin Receptor GPCR/G Protein
Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate) 是一种由 28 个氨基酸组成的激素,由心脏产生并分泌,以响应心脏损伤和机械拉伸。Carperitide acetate 抑制内皮素-1 (endothelin-1) 分泌。
TP1033 Transdermal Peptide Disulfide

Transdermal Peptide,TD 1 (peptide)

Transdermal Peptide (TD 1 peptide) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Pep
TP2401 Peptide T amide

D-Ala(1)-peptide T amide

Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy.
T29856 Aleplasinin

PAZ 417,PAZ417,PAZ-417

PAI-1 Metabolism
Aleplasinin (PAZ 417) 是纤溶酶原激活物抑制剂 1 (PAI-1) 的选择性和口服活性抑制剂,是纤溶系统的关键负调节剂。 Aleplasinin 可用于阿尔茨海默病研究。
T39017 OVA-E1 peptide

OVA-E1 peptide

OVA-E1 peptide, a variant antagonist of SIINFEKL [OVA (257-264)], elicits comparable activation of the p38 and JNK cascades in both mutant and wild-type thymocytes.
TP1032 Transdermal Peptide TFA (918629-48-8 free base)

Transdermal Peptide TFA,TD 1 (peptide) (TFA)

Transdermal Peptide TFA (TD 1 Peptide TFA) is an 11-amino acid polypeptide that binds to Na+/K+ -atpase beta-subunit (ATP1B1) and interacts with the C terminal of ATP1B1.Transdermal Peptide TFA can enhance the transmission of some large molecules in the s
T82456 EPO mimetic peptide-1

EMP-1

EPO mimetic peptide-1 (EMP-1)为含20个氨基酸的多肽,该化合物具有促进细胞增殖、影响细胞周期以及诱导网织细胞产生的作用。
TP1526 Fibronectin CS1 Peptide

he connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontan
T80521 Caveolin-1 (82-101) amide (human, mouse, rat)

Caveolin-1 scaffolding domain peptide

c-Met/HGFR Tyrosine Kinase/Adaptors
Caveolin-1 (82-101) amide (human, mouse, rat) (Caveolin-1 scaffolding domain peptide) 是抑制酪氨酸激酶的肽,可逆转多器官衰老相关的有害变化。
TP2208 PDZ1 Domain inhibitor peptide

Others Others
Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95
T41019 Histone H1-derived Peptide

Histone H1-derived Peptide

Histone H1-derived peptide is a phosphopeptide with peptide substrates that consist of a sequence aligned with the optimal recognition motif for cyclin-dependent kinases (CDKs).
T80962 TPNQRQNVC

LRH-1 peptide

TPNQRQNVC为HLA-B0702的九肽抗原决定簇,能激活CD8+ T细胞的免疫响应。

化合物

Anti-Inflammatory Peptide 1 Acetate
Cat.No: T21606L
Synonym: Anti-Inflammatory Peptide 1 Acetate(118850-70-8 Free base)
Target: Phospholipase
Amyloid β Peptide (42-1)(human) acetate
Cat.No: TP1359L
Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)
Target: Beta Amyloid
GnRH Associated Peptide (GAP) (1-13), human Acetate
Cat.No: T21649L
Synonym: GnRH Associated Peptide (GAP) (1-13), human Acetate (100111-07-7 Free base)
Target: Others
C-Type Natriuretic Peptide (CNP) (1-22), human acetate
Cat.No: T39392L
Synonym: C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)
Target: Others
Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
Cat.No: TP1219
Synonym: ANP (1-28), human, porcineANP(1-28)
Target:
C-Type Natriuretic Peptide (CNP) (1-22), human
Cat.No: TP1187
Synonym: CNP (1-22), human
Target: RAAS
Transdermal Peptide Disulfide Acetate
Cat.No: TP1033L
Synonym: TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base)
Target: ATPase
Fibronectin CS1 Peptide acetate
Cat.No: TP1526L1
Synonym:
Target: Others
Transdermal Peptide (TD 1 (peptide))
Cat.No: T37766
Synonym:
Target:
Sperm-activating peptide 1
Cat.No: TP2411
Synonym:
Target:
TRAP-6
Cat.No: T7625
Synonym: PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)
Target: Protease-activated Receptor
Tyrosine Kinase Peptide 1
Cat.No: T39178
Synonym:
Target:
Mast Cell Degranulating Peptide HR-2 acetate
Cat.No: TP1497L
Synonym: Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base)
Target: Others
Calmodulin Binding Peptide 1
Cat.No: TP1710
Synonym:
Target:
Bombinin-Like Peptide (BLP-1)
Cat.No: TP1754
Synonym: Bombinin-Like Peptide BLP-1
Target:
NFAT Inhibitor
Cat.No: TP1015
Synonym: VIVIT peptide
Target: Others
Glucagon-like peptide 1 (1-37), human
Cat.No: TP1148
Synonym: HuGLP-1
Target:
IFN-α Receptor Recognition Peptide 1
Cat.No: TP1117
Synonym: IRRP1
Target:
Glucagon-like peptide 1 (1-37), human acetate
Cat.No: TP1148L
Synonym:
Target: Glucagon Receptor
Brain Natriuretic Peptide (1-32), rat
Cat.No: TP1756
Synonym: Brain Natriuretic Peptide (BNP) (1-32), rat
Target:
SLLK, Control Peptide for TSP1 Inhibitor acetate
Cat.No: TP1833L
Synonym: SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base)
Target: Others
Amyloid-β (1-8, A2V) Peptide
Cat.No: T37369
Synonym: Amyloid-β (1-8, A2V) Peptide
Target:
Amyloid-β (1-8) Peptide
Cat.No: T37368
Synonym:
Target:
TAT
Cat.No: TP1809
Synonym:
Target: HIV Protease
Glucagon-like peptide 1 (1-37), human TFA
Cat.No: TP1147
Synonym: HuGLP-1 TFA
Target:
TAE-1
Cat.No: T21825
Synonym:
Target: Beta Amyloid, AChE
Prolactin Releasing Peptide (1-31), human
Cat.No: TP1769
Synonym:
Target:
RGD peptide (GRGDNP) (TFA) (114681-65-1 free base)
Cat.No: TP1311
Synonym: RGD peptide (GRGDNP) (TFA)
Target:
Amyloid-β (1-42) Peptide (trifluoroacetate salt)
Cat.No: T37367
Synonym:
Target:
C-Type Natriuretic Peptide (1-53), human
Cat.No: TP1581
Synonym:
Target:
Biotin-Amyloid-β (1-42) Peptide (trifluoroacetate salt)
Cat.No: T37200
Synonym:
Target:
Brain Natriuretic Peptide (1-32), rat acetate
Cat.No: T35832
Synonym:
Target:
Atrial Natriuretic Peptide (ANP) (1-28), rat
Cat.No: TP1221
Synonym: Atrial natriuretic factor (1-28) (rat)
Target:
TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt)
Cat.No: T37472
Synonym:
Target:
FPS-ZM1
Cat.No: T3259
Synonym:
Target: Beta Amyloid, advanced glycation end products
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled
Cat.No: T39244
Synonym:
Target:
Bivalirudin
Cat.No: T5519
Synonym: BG-8967,比伐卢定,Hirulog-1
Target: Thrombin
C-Type Natriuretic Peptide (CNP) (1-22), human TFA
Cat.No: T39392
Synonym:
Target:
Carperitide acetate
Cat.No: TP1220L
Synonym: 醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
Target: Endothelin Receptor
Transdermal Peptide Disulfide
Cat.No: TP1033
Synonym: Transdermal Peptide,TD 1 (peptide)
Target:
Peptide T amide
Cat.No: TP2401
Synonym: D-Ala(1)-peptide T amide
Target:
Aleplasinin
Cat.No: T29856
Synonym: PAZ 417,PAZ417,PAZ-417
Target: PAI-1
OVA-E1 peptide
Cat.No: T39017
Synonym: OVA-E1 peptide
Target:
Transdermal Peptide TFA (918629-48-8 free base)
Cat.No: TP1032
Synonym: Transdermal Peptide TFA,TD 1 (peptide) (TFA)
Target:
EPO mimetic peptide-1
Cat.No: T82456
Synonym: EMP-1
Target:
Fibronectin CS1 Peptide
Cat.No: TP1526
Synonym:
Target:
Caveolin-1 (82-101) amide (human, mouse, rat)
Cat.No: T80521
Synonym: Caveolin-1 scaffolding domain peptide
Target: c-Met/HGFR
PDZ1 Domain inhibitor peptide
Cat.No: TP2208
Synonym:
Target: Others
Histone H1-derived Peptide
Cat.No: T41019
Synonym: Histone H1-derived Peptide
Target:
TPNQRQNVC
Cat.No: T80962
Synonym: LRH-1 peptide
Target:
Cat. No. Product Name Target Signaling Pathways
T1686 Hematoxylin

苏木精,Hydroxybrazilin,Natural Black 1,Haematoxylin

Beta Amyloid; Others Neuroscience; Others
Hematoxylin (Natural Black 1) 是一种天然存在的类黄酮化合物,衍生自木柴树Haematoxylon campechianum。它是一种组织学上的核染色剂,也是一种有效的Aβ42原纤维形成的抑制剂,IC50=1.6 µM。
T0883 Tramiprosate

Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸

Beta Amyloid; GABA Receptor Membrane transporter/Ion channel; Neuroscience
Tramiprosate (Alzhemed) 是一种具有口服活性的、可透过血脑屏障的天然氨基酸,存在于各种红色海藻中,能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物,具有神经保护,抗惊厥和抗高血压的活性。
T2961 Notoginsenoside R1

Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1

Apoptosis; ERK; Beta Amyloid Apoptosis; MAPK; Neuroscience
Notoginsenoside R1 (Sanchinoside R1) 是一种从三七中分离出来的皂苷,具有抗氧化、抗炎、抗血管生成和抗凋亡的活性。它有神经保护和抗缺血/再灌注损伤的心脏保护作用。
T2777 Ginsenoside Rg1

Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2

Apoptosis; Beta Amyloid; NF-κB Apoptosis; Neuroscience; NF-κB
Ginsenoside Rg1 (Panaxoside Rg1) 是人参的主要活性成分之一,可减少NF-κB 核易位。它改善认知功能受损,通过降低大脑Aβ水平来发挥作用。
T3S1729 Dihydrolycorine

Others Others
Dihydrolycorine 是分离自Lycoris radiate 草药中,是一种真核细胞中蛋白质合成的抑制剂。
T37526 2-Oleoylglycerol

2-Oleoyl Glycerol,2-OG,2-Monoolein

GPR Endocrinology/Hormones; GPCR/G Protein
2-Oleoylglycerol 是一种存在于棕榈仁、葵花籽和米糠中的脂质。2-Oleoylglycerol 可当作一种 GPR119 激动剂,具有神经保护作用,可诱导胰高血糖素样肽 1 (GLP-1) 分泌。2-Oleoylglycerol 可用于非酒精性脂肪性肝炎造模。
TN1038 Galgravin

Apoptosis Apoptosis
Galgravin 是望春花中的一种天然产物,具有抗炎和体外细胞毒活性,能诱导白血病细胞凋亡。
T81845 Maximin H7

Maximin H7为源自Bombina maxima蟾蜍的抗菌肽。
T80310 Plantaricin A

PlnA

Plantaricin A,源自Lactobacillus plantarum,为一种具有抗细菌活性的肽类化合物。
T80356 Bombinin H2

Bombinin H2, 源自Bombina variegata蛾皮肤的抗菌肽。
T80348 Pleurocidin

Pleurocidin为一种从Winter Flounder皮肤分泌物中提取的抗菌肽。
T81843 Maximin S4

Maximin S4为Bombina maxima蟾蜍源抗菌肽,对支原体表现出抗菌效能。
T80314 Dermaseptin-S2

Dermaseptin-S2为源自青蛙皮肤的抗菌肽,具有对丝状真菌的抗性。
T80311 Dermaseptin-S3

Dermaseptin-S3为源自青蛙皮肤的抗菌肽,具备抗丝状真菌活性。
T80324 Maximin 1

Maximin 1,源自Bombina maxima皮肤分泌物的抗菌肽,具备针对肿瘤细胞的细胞毒性及杀精能力。
T73888 Berninamycin D

Berninamycin D 是一种环状肽真菌代谢物,从 Streptomyces bernensis 中分离出来。
T80416 Mram 8

Mram 8为源自堇菜科植物堇菜中提取的环肽。
T80309 Dermaseptin-S4

Dermaseptin-S4为源自青蛙皮肤的抗菌肽,具有针对丝状真菌的抗菌活性。
T80315 Dermaseptin-S1

Dermaseptin-S1为源自青蛙皮肤的抗菌肽,具备对抗丝状真菌的活性。
T80359 Bombinin H5

Bombinin H5为源自蛾Bombina variegata表皮的抗菌肽。
T80331 XT-2 peptide

XT-2 peptide, 源自热带爪蟾(Xenopus tropicalis)皮肤分泌物的抗菌肽,具有强效抗E.coli活性,其最小抑菌浓度(MIC)为8 μM。
T80308 Dermaseptin-S5

Dermaseptin-S5为源自青蛙表皮的抗菌肽,具有针对丝状真菌的抗菌活性。
T80327 Maximin 4

Maximin 4, 源自Bombina maxima皮肤分泌物的抗菌肽,展现对肿瘤细胞的细胞毒性及杀精效应。
T80347 FLGFVGQALNALLGKL-NH2

FLGFVGQALNALLGKL-NH2 是源自蛙类的抗菌肽,对金黄色葡萄球菌 ATCC 29213 表现出活性(MIC=32 μM)。
T80328 Maximin 5

Maximin 5,源自Bombina maxima皮肤分泌,此抗菌肽对肿瘤细胞显示出显著的细胞毒性及杀精效果。
T80358 Bombinin H3

Bombinin H3为源自蛾Bombina variegata皮肤的抗菌肽。其对大肠杆菌D21的致死浓度为3.7 μM,而针对金黄色葡萄球菌Cowan 1的致死浓度为2.4 μM。
T80344 Aeschna defensin

Aeschna defensing是源自蜻蜓水生幼虫血淋巴的抗菌肽,对革兰氏阳性菌具有显著活性。
T80337 Maximin 63

Maximin 63是一种具有强抗金黄色葡萄杆菌活性的蟾蜍大脑来源抗菌肽(MIC为18.8 μg/mL)。
T76027 β-Endorphin, equine TFA

β-Endorphin, equine TFA,是具备强效亲和力于μ和δ阿片受体(μ/δ opioid receptors)的内源性阿片类多肽,主要功能包括止痛。
T75743 HA Peptide TFA

HA Peptide (TFA) 为源自人类流感血凝素 (HA) 的九氨基酸多肽, 在细胞生物学与生物化学领域内广泛应用于目标蛋白的分离、纯化、检测及追踪。
T75722 Chlorotoxin TFA

Chlorotoxin TFA,一种从蝎子毒液中分离出的多肽,作为氯离子通道 (chloride channel) 的阻断剂,具备抗癌活性。
T80325 Maximin 2

Maximin 2,一种来自Bombina maxima皮肤分泌物的抗菌肽,表现出对肿瘤细胞的细胞毒性及对精子的杀伤效果。
T75767 Parasin I TFA

Parasin I (TFA) 是一种含有19个氨基酸残基的多肽,源自鲶鱼皮肤中分离出的组蛋白H2A,具备抗菌功能。
T80355 Bombinin H1

Bombinin H1是Bombina variegata蛾皮肤中提取的抗菌肽。该肽对大肠杆菌D21的致死浓度为3.8μM,而对金黄色葡萄球菌Cowan 1的致死浓度为2.1μM。
T75753 Magainin 1 TFA

Magainin 1 TFA (Magainin I TFA) 是从 Xenopus laevis 皮肤中分离出的一种抗菌和两亲性肽。Magainin 1 TFA 对多种革兰氏阴性和革兰氏阳性细菌均表现出抗生素活性。
T80357 Bombinin H7

Bombinin H7 是一种抗菌肽,提取自铃蟾Bombina的皮肤分泌物。该化合物对Bacillus megateriumBm11显示出高效活性,其致死浓度达到25.2 μM。
T80360 Bombinin H4

Bombinin H4,蛾Bombina variegata皮肤中的抗菌肽,其对大肠杆菌D21和金黄色葡萄球菌Cowan 1的致死浓度分别为4.8 μM和3.3 μM。
T80330 XT-1

XT-1是一种抗菌肽,源自热带爪蟾Xenopus tropicalis的皮肤分泌物,表现出对S.aureus、E.coli和C.albicans的强烈活性,其最小抑菌浓度(MIC)分别为5μM、6μM和50μM。
T80353 Maximin 32

Maximin 32 是源于蟾蜍大脑的抗菌肽,对金黄色葡萄球菌和大肠杆菌表现出活性,其 MIC 值分别为 9.4 和 18.8 μg/mL。
T73653 Pexiganan

Pexiganan(MSI 78 free base),maganin 2 的合成类似物,是一种具有口服活性的广谱强效抗菌肽,主要用于研究糖尿病足溃疡等相关感染。
T80342 XT-4

XT-4,一种抗菌肽,源自热带爪蟾 (Xenopus tropicalis) 皮肤分泌物,对E.coli表现出高效的抑菌作用,最小抑制浓度 (MIC) 为18 μM。
T80326 Maximin 3

Maximin 3是一种抗菌肽,来源于Bombina maxima的皮肤分泌物。它对肿瘤细胞表现出细胞毒性,并具有杀精作用。此外,Maximin 3还展示出显著的抗HIV活性。
T80352 Maximin 31

Maximin 31 是抗菌肽,源自蟾蜍大脑。该化合物对金黄色葡萄球菌和大肠杆菌表现出抗菌活性,其最小抑菌浓度(MIC)值分别为 37.5 μg/mL 和 75 μg/mL。
T14121 Actinonin

(-)-Actinonin

Aminopeptidase Metabolism
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase, it also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
T81016 Terrelumamide A

Terrelumamide A是一种带有lumazine结构的肽类化合物,从海洋真菌Aspergillus terreus的培养物中提取分离得到。该化合物因增强胰岛素敏感性而显示出药理作用,并在DNA序列识别方面具有潜在应用价值。
T75647 Nostosin G

Nostosin G 是一种独特的线性肽,含有 3 个亚基,4-羟基苯乳酸 (Hpla),高酪氨酸 (Hty) 和精氨酸。Nostosin G 具有有效的胰蛋白酶抑制特性,其 IC50值为 0.1 μM。
T80350 Maximin 15

Maximin 15为源自蟾蜍大脑的抗菌肽,具有针对金黄色葡萄球菌、大肠杆菌和枯草芽孢杆菌的活性,其最小抑菌浓度(MIC)值依次为9.4, 18.8, 75 μg/mL。
T80354 Maximin 39

Maximin 39为源自蟾蜍大脑的抗菌肽,具有针对金黄色葡萄球菌(Staphylococcus aureus)和大肠杆菌(Escherichia coli)的活性,其最小抑菌浓度(MIC)值分别为18.8 μg/mL和37.5 μg/mL。
T80346 Tur1A

Tur1A,宽吻海豚源抗菌肽,通过结合核糖体并阻断蛋白质合成从起始阶段至延伸阶段的转变,抑制细菌蛋白质合成。
T80351 Maximin 28

Maximin 28为源自蟾蜍大脑的抗菌肽,对金黄色葡萄球菌(Staphylococcus aureus)、大肠杆菌(Escherichia coli)及枯草芽孢杆菌(Bacillus subtilis)表现出抗菌活性,其MIC值分别为4.7、9.4、75 μg/mL。
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天然产物

Hematoxylin
Cat.No: T1686
Synonym: 苏木精,Hydroxybrazilin,Natural Black 1,Haematoxylin
Target: Beta Amyloid, Others
Tramiprosate
Cat.No: T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸
Target: Beta Amyloid, GABA Receptor
Notoginsenoside R1
Cat.No: T2961
Synonym: Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1
Target: Apoptosis, ERK, Beta Amyloid
Ginsenoside Rg1
Cat.No: T2777
Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2
Target: Apoptosis, Beta Amyloid, NF-κB
Dihydrolycorine
Cat.No: T3S1729
Synonym:
Target: Others
2-Oleoylglycerol
Cat.No: T37526
Synonym: 2-Oleoyl Glycerol,2-OG,2-Monoolein
Target: GPR
Galgravin
Cat.No: TN1038
Synonym:
Target: Apoptosis
Maximin H7
Cat.No: T81845
Synonym:
Target:
Plantaricin A
Cat.No: T80310
Synonym: PlnA
Target:
Bombinin H2
Cat.No: T80356
Synonym:
Target:
Pleurocidin
Cat.No: T80348
Synonym:
Target:
Maximin S4
Cat.No: T81843
Synonym:
Target:
Dermaseptin-S2
Cat.No: T80314
Synonym:
Target:
Dermaseptin-S3
Cat.No: T80311
Synonym:
Target:
Maximin 1
Cat.No: T80324
Synonym:
Target:
Berninamycin D
Cat.No: T73888
Synonym:
Target:
Mram 8
Cat.No: T80416
Synonym:
Target:
Dermaseptin-S4
Cat.No: T80309
Synonym:
Target:
Dermaseptin-S1
Cat.No: T80315
Synonym:
Target:
Bombinin H5
Cat.No: T80359
Synonym:
Target:
XT-2 peptide
Cat.No: T80331
Synonym:
Target:
Dermaseptin-S5
Cat.No: T80308
Synonym:
Target:
Maximin 4
Cat.No: T80327
Synonym:
Target:
FLGFVGQALNALLGKL-NH2
Cat.No: T80347
Synonym:
Target:
Maximin 5
Cat.No: T80328
Synonym:
Target:
Bombinin H3
Cat.No: T80358
Synonym:
Target:
Aeschna defensin
Cat.No: T80344
Synonym:
Target:
Maximin 63
Cat.No: T80337
Synonym:
Target:
β-Endorphin, equine TFA
Cat.No: T76027
Synonym:
Target:
HA Peptide TFA
Cat.No: T75743
Synonym:
Target:
Chlorotoxin TFA
Cat.No: T75722
Synonym:
Target:
Maximin 2
Cat.No: T80325
Synonym:
Target:
Parasin I TFA
Cat.No: T75767
Synonym:
Target:
Bombinin H1
Cat.No: T80355
Synonym:
Target:
Magainin 1 TFA
Cat.No: T75753
Synonym:
Target:
Bombinin H7
Cat.No: T80357
Synonym:
Target:
Bombinin H4
Cat.No: T80360
Synonym:
Target:
XT-1
Cat.No: T80330
Synonym:
Target:
Maximin 32
Cat.No: T80353
Synonym:
Target:
Pexiganan
Cat.No: T73653
Synonym:
Target:
XT-4
Cat.No: T80342
Synonym:
Target:
Maximin 3
Cat.No: T80326
Synonym:
Target:
Maximin 31
Cat.No: T80352
Synonym:
Target:
Actinonin
Cat.No: T14121
Synonym: (-)-Actinonin
Target: Aminopeptidase
Terrelumamide A
Cat.No: T81016
Synonym:
Target:
Nostosin G
Cat.No: T75647
Synonym:
Target:
Maximin 15
Cat.No: T80350
Synonym:
Target:
Maximin 39
Cat.No: T80354
Synonym:
Target:
Tur1A
Cat.No: T80346
Synonym:
Target:
Maximin 28
Cat.No: T80351
Synonym:
Target:
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