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Search Results for " tfa "

1221

抑制剂 & 化合物

16

天然产物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TF0046	TFA
	TFA 在生命科学相关研究中具有广泛的应用。
TP1215	Abaloparatide TFA BA 058 TFA,Abaloparatide TFA (247062-33-5 free base),BIM 44058 TFA	Others	Others
	Abaloparatide TFA (BIM 44058 TFA) 是一种甲状旁腺激素相关蛋白 (PTHrP) 类似物药物，与相关药物特立帕肽一样用于治疗骨质疏松症。
T14665L	Motixafortide TFA(664334-36-5,Free) TF 14016 TFA,BKT140 TFA,BL-8040 TFA,T140 TFA	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) 是 CXCR4 的拮抗剂，IC50 为～1 nM。它通过改变 miR-15a/16-1 表达下调 ERK、BCL-2、MCL-1 和 cyclin-D1 来诱导 AML 原始细胞凋亡。
T7326	6H05 (TFA) 6H05 TFA,6H05 trifluoroacetate	Ras	GPCR/G Protein; MAPK
	6H05 TFA (6H05 trifluoroacetate) 是一种选择性变构致癌突变体 K-Ras(G12C) 抑制剂。
T26641L	Apadenoson TFA BAY 68-4986 TFA,Apadenoson TFA(250386-15-3 Free base),Discontinued TFA	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Apadenoson TFA 是一种有效的腺苷 A2A 受体（A2AR）激动剂,可用于提高SARS感染患者的存活率。
TP1346	CYN 154806 TFA CYN 154806 TFA	Somatostatin	GPCR/G Protein
	CYN 154806 TFA(183658-72-2 free base) 是一种环状八肽，是一种有效的选择性生长抑素 sst2 受体拮抗剂。对于重组 sst2、sst1、sst3、sst4 和 sst5 受体，pIC50 值分别为 8.58、5.41、6.07、5.76 和 6.48。
T33876L1	Panomifene TFA Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Panomifene TFA（GYKl13504 TFA）是一种小分子 ERs 拮抗剂，具有抗癌活性，可用于研究乳腺癌和肌肉骨骼疾病。
T11237L	Camizestrant TFA Camizestrant TFA(2222844-89-3 Free base),AZD-9833 TFA	Estrogen Receptor/ERR	Endocrinology/Hormones
	Camizestrant TFA (AZD-9833 TFA) 是一种有效的口服雌激素受体拮抗剂。
T8768	MM-102 TFA HMTase Inhibitor IX TFA	Histone Methyltransferase	Chromatin/Epigenetic
	MM-102 TFA (HMTase Inhibitor IX TFA) 是一种有效的 WDR5/MLL 相互作用抑制剂，在 WDR5 结合检测中，IC50为 2.4 nM，Ki 小于 1 nM。
TP1291	Epithalon TFA (307297-39-8 free base) Epithalon TFA	Others	Others
	Epithalon TFA (307297-39-8 free base) (Epithalon TFA) 是一种抗衰老剂和端粒酶激活剂。
T13346L	WQ3810 TFA WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA	Antifungal	Microbiology/Virology
	WQ3810 TFA 是一种可口服的氟喹诺酮，具有抗菌活性，对结核分枝杆菌有抑制作用，抑制氧氟沙星耐药麻风分枝杆菌的 DNA 旋转酶活性。
TP1796	Albiglutide TFA (782500-75-8 free base) Albiglutide TFA	Glucagon Receptor	GPCR/G Protein
	Albiglutide TFA (782500-75-8 free base) (Albiglutide TFA) 是一种长效 GLP-1 受体激动剂，用于治疗 2 型糖尿病 (T2DM)。
TP2050L	CTAP(TFA） (103429-32-9 free base) CTAP(TFA）	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	CTAP(TFA) (103429-32-9 free base) 是一种有效的、高度选择性的、脑渗透性 μ-阿片受体拮抗剂，IC50 为 3.5 nM。它的选择性比 δ 阿片类药物 (IC50=4500 nM) 和生长抑素受体高 1200 倍以上。 CTAP TFA 可用于研究 L-DOPA 诱导的运动障碍 (LID)
T16790L	Rotigaptide TFA(355151-12-1 free base) Rotigaptide TFA	Gap Junction Protein	Cytoskeletal Signaling
	Rotigaptide TFA(355151-12-1 free base) 是一种新型的 Cx43 特异性调节剂，是一种有效的 AAP。 Rotigaptide 可防止 Cx43 介导的间隙连接通讯的解偶联，并使急性代谢应激期间的细胞间通讯正常化。
T5862	Ezatiostat TFA TER199(free base),Ezatiostat TFA (free base),Ezatiostat,TLK199	GST	oxidation-reduction
	Ezatiostat TFA (TLK199) 是一种具有造血刺激活性的谷胱甘肽 S-转移酶 (GST) P1-1 的脂质体小分子谷胱甘肽类似物抑制剂。
T27250L	Elarofiban TFA Elarofiban TFA（198958-88-2 Free base）,RWJ-53308 TFA	Integrin	Cytoskeletal Signaling
	Elarofiban TFA (RWJ-53308 TFA) 是一种新型且具有口服活性和选择性的 GPIIb/IIIa 拮抗剂，可用于研究心血管疾病。
T17927	(S,R,S)-AHPC TFA VH032-NH2 TFA,VHL ligand 1 TFA	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC TFA (VHL ligand 1 TFA) 是一种 VH032-based VHL ligand，可用于募集 von Hippel-Lindau (VHL)蛋白。它能够利用 linker 与靶蛋白配体连接，形成 PROTAC 分子。
T30191L	Atecegatran TFA Atecegatran TFA(917904-13-3 Free base）,AR-H067637 TFA	Others	Others
	Atecegatran TFA 常被当作一种抗凝血剂，可用来治疗心血管疾病。
TP1348	FC131 TFA (606968-52-9 free base) FC131 TFA	HIV Protease; CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	FC131 TFA (606968-52-9 free base) (FC131 TFA) 是 CXCR4 的拮抗剂，可抑制 [125I] -sdf-1 与 CXCR4 的结合（IC50：4.5 nM），并具有抗 HIV 活性。
TP1086	Men 10376 TFA(135306-85-3,free) Men 10376 TFA,Neurokinin-2 receptor antagonist TFA	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) 是一种有效的选择性速激肽 nk-2 受体拮抗剂，对大鼠小肠 nk-2 受体的 K I 值为 4.4 M。
TP1079	(Arg)9 TFA (143413-47-2 free base) Nona-L-arginine (TFA),(Arg)9 TFA,Peptide R9 (TFA)	Others	Others
	(Arg)9 TFA (Peptide R9 TFA) 是一种可渗透细胞的多肽，在谷氨酸模型实验模型中保护神经(IC50:0.78 μM)。
TP1300	GsMTx4 TFA (1209500-46-8 free base) GsMTx4 TFA	Piezo Channel	Membrane transporter/Ion channel
	GsMTx4 TFA (1209500-46-8 free base) (GsMTx4 TFA) 是一种蜘蛛毒肽，可选择性地抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透机械敏感通道 (MSC)。
TP2036L	DPDPE TFA (88373-73-3 free base) DPDPE TFA	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	DPDPE TFA 是选择性 δ-阿片受体激动剂肽，在体内具有镇痛作用。
T68023L	Tolnapersine TFA Tolnapersine TFA(70312-00-4 Free base)	Dopamine Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Tolnapersine TFA 是混合多巴胺激动剂和α肾上腺素受体拮抗剂。
T68166L	Traxanox TFA Traxanox TFA(58712-69-9 Free base)	Others	Others
	Traxanox TFA 是一种可口服的利尿剂。Traxanox TFA 在体外增强小鼠腹膜巨噬细胞或大鼠腹膜多形核白细胞对酵母颗粒的吞噬作用。Traxanox TFA 对抑制BALB/c小鼠抗体产生的恢复作用。
T34921L1	Tresperimus TFA Tresperimus TFA(160677-67-8 Free base)	Others	Others
	Tresperimus TFA 可作为一种免疫制剂使用，可用于研究视网膜炎。
TP1430	DTP3 TFA (1809784-29-9 free base) DTP3 TFA	Others	Others
	DTP3 TFA (1809784-29-9 free base) (DTP3 TFA) 是一种有效的选择性 GADD45β/MKK7（生长停滞和 DNA 损伤诱导型 β/丝裂原活化蛋白激酶激酶 7）抑制剂。
T61345L	Orbofiban TFA Orbofiban TFA(163250-90-6 Free base)	Integrin	Cytoskeletal Signaling
	Orbofiban TFA 是一种具有口服活性的GPIIb/IIIa血小板受体拮抗剂，对血小板聚集有抑制作用，可用于研究不稳定冠状动脉综合征。
TP1254	[Met5]-Enkephalin, amide TFA 5-Methionine-enkephalin amide (TFA)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	[Met5]-Enkephalin, amide TFA (5-Methionine-enkephalin amide (TFA)) (60117-17-1 free base) 是一种 δ 阿片受体激动剂以及推定的 ζ (zeta) opioid 受体。
TP1318	Antennapedia Peptide TFA(188842-14-0 free base) Antennapedia Peptide(TFA)	Others	Others
	Antennapedia Peptide TFA (188842-14-0 free base) 是一种 16 个氨基酸的肽，是细胞穿透肽家族的成员，最初来源于果蝇转录因子 Antennapedia 的 60 个氨基酸长的同源域。
TP2158	TRV-120027 TFA TRV-120027 TFA (1234510-46-3 free base)	RAAS; Arrestin	Endocrinology/Hormones; GPCR/G Protein
	TRV-120027 TFA 是一种血管紧张素 II 介导的血管收缩抑制剂，可增加心肌细胞的收缩力。它是一种偏向 β-arrestin-1 的 AT1R 激动剂，可与 ß-arrestins 结合，同时阻断 G 蛋白信号传导。它通过阳离子通道亚家族 C3 (TRPC3) 偶联诱导急性儿茶酚胺分泌，并促进在质膜上形成由 AT1R-β-arrestin-1-TRPC3-PLCγ 组成的大分子复合物。
TP1918L	Lys-[Des-Arg9]Bradykinin,TFA Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa)	Bradykinin Receptor	GPCR/G Protein
	Lys-[Des-Arg9]Bradykinin,TFA (71800-36-7 free base) 是内源性强效和高选择性的缓激肽 B1 受体激动剂（对人 B1 和 B2 受体的 Ki 值分别为 0.12 和 > 30000 nM）。降低体内外周血管阻力的降压药。比 [Des-Arg9]-缓激肽强 16 倍。
TP1065	PAR-4 Agonist Peptide, amide TFA PAR-4-AP (TFA),AY-NH2 (TFA)	Protease-activated Receptor	GPCR/G Protein
	PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)) 是一种蛋白酶激活受体 4 (PAR-4) 激动剂，对 PAR-1 或 PAR-2 均无影响，其作用可被 PAR-4 拮抗剂阻断。
TP1240	Adrenocorticotropic Hormone (ACTH) (18-39), human TFA CLIP (human) (TFA)	Others	Others
	Adrenocorticotropic Hormone (ACTH) (18-39), human TFA (CLIP human TFA) 是一种似皮质促素中叶肽，由垂体中叶的促黑素细胞产生。
T36201L	AZD5582 TFA AZD5582 TFA（1258392-53-8 free base）	Apoptosis; IAP	Apoptosis
	AZD5582 TFA 是一种有效的 IAP 拮抗剂，可与 cIAP1，cIAP2 和 XIAP 的 BIR3 结构域结合, IC50 值分别为 15，21，15 nM。AZD5582 TFA可诱导细胞凋亡。
T64133L	Laniquidar TFA Laniquidar TFA(197509-46-9 Free base),R101933	P-gp	Membrane transporter/Ion channel; Neuroscience
	Laniquidar TFA (R101933) 是一种新型口服非竞争性P-糖蛋白(P-gp)抑制剂，IC50 值为 0.51 μM。Laniquidar的生物利用度有限，可用于调节多药耐药性转运体。Laniquidar可用于研究急性髓性白血病(AML)和骨髓增生异常综合征(MDS)。
T67972L	Amp579 TFA Amp579 TFA(213453-89-5 Free base)	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Amp579 TFA 是一种新型腺苷 A1/A2a 受体激动剂，诱导针对体内心肌休克的急性和延迟预处理。
TP1067	Pam3CSK4 TFA (112208-00-1 free base) Pam3CSK4 TFA,Pam3Cys-Ser-(Lys)4 TFA	TLR	Immunology/Inflammation
	Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) 是 Toll 样受体 1/2 激动剂，对人 TLR1/2 的EC50为 0.47 ng/mL。
T33836L	Oxamisole TFA Oxamisole TFA（99258-56-7 Free base)	Antiviral	Immunology/Inflammation
	Oxamisole TFA 是一种可口服且具有选择性的 T 细胞免疫调节剂，可用于研究病毒感染。
T7666	Valorphin TFA(144313-54-2(free base)) Valorphin TFA(144313-54-2(free bas))	Others	Others
	Valorphin TFA(144313-54-2(free base)) 是具有 opioid 类镇痛活性的二氢戊酸的半合成衍生物。
TP1200	CGRP (83-119), rat TFA Calcitonin Gene Related Peptide(83-119), rat TFA	Others	Others
	CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) 是一种由 37 个氨基酸组成的神经肽降钙素家族，通过降钙素受体样受体起作用。
T28072L	MLN-3897 TFA MLN-3897 TFA(1010731-97-1 Free base)	CCR	Immunology/Inflammation; Microbiology/Virology
	MLN-3897 TFA 是一种有效的CCR1 拮抗剂，对 125I-MIP-1α 与 THP-1 细胞膜的结合具有抑制作用。
T7760	Thalidomide-O-amido-C3-NH2 TFA Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA	E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase	PROTAC
	Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物，。
TP1523	PKG inhibitor peptide TFA (82801-73-8 free base) PKG inhibitor peptide TFA	PKA	Tyrosine Kinase/Adaptors
	PKG inhibitor peptide TFA (82801-73-8 free base) 是 ATP 竞争性 cGMP 依赖性蛋白激酶 (PKG) 的抑制剂。
TP1216	CaM kinase II inhibitor TFA salt Autocamtide-2-related inhibitory peptide (TFA)	CaMK	Neuroscience
	CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide(TFA)) 是一种高度特异性和有效的 CaMKII 抑制剂，IC50 为 40 nM。
TP1433	CMD178 TFA	STAT	JAK/STAT signaling; Stem Cells
	CMD178 TFA 是一种先导肽，可始终降低由 IL-2/s IL-2Rα 信号传导诱导的 Foxp3 和 STAT5 的表达。
TP1275	3X FLAG peptide TFA (402750-12-3 free base) 3X FLAG peptide TFA	Others	Others
	3X FLAG peptide TFA (402750-12-3 free base) (3X FLAG peptide TFA) 是一种含有 23 个氨基酸残基的合成肽。 Asp-Tyr-Lys-Xaa-Xaa-Asp 基序在肽中重复了 3 次。
TP1947L	P110 TFA	Others	Others
	P110 TFA 是一种 dynamin-related protein 1 (Drp1) 抑制剂，抑制 Drp1 GTPase 活性。
T37496L	Alamandine TFA	RAAS	Endocrinology/Hormones
	Alamandine TFA 是肾素-血管紧张素系统 (RAS) 的成员，是一种血管活性肽，是 G 蛋白偶联受体 MrgD 的内源性配体。它通过抗高血压作用来保护肾脏和心脏。
T20435L	Leuphasyl TFA	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Leuphasyl TFA 是一种酰胺肽，一种 δ-阿片受体激动剂，是一种抗降解的长效 Leu-脑啡肽类似物，用于研究 δ 阿片受体的信号通路。它是一种有效的长效 Leu-脑啡肽类似物，可抵抗酶促降解。

化合物

Cat.No: TF0046

Abaloparatide TFA

Cat.No: TP1215

Synonym: BA 058 TFA,Abaloparatide TFA (247062-33-5 free base),BIM 44058 TFA

Target: Others

Motixafortide TFA(664334-36-5,Free)

Cat.No: T14665L

Synonym: TF 14016 TFA,BKT140 TFA,BL-8040 TFA,T140 TFA

Target: CXCR

Cat.No: T7326

Synonym: 6H05 TFA,6H05 trifluoroacetate

Target: Ras

Apadenoson TFA

Cat.No: T26641L

Synonym: BAY 68-4986 TFA,Apadenoson TFA(250386-15-3 Free base),Discontinued TFA

Target: Adenosine Receptor

CYN 154806 TFA

Cat.No: TP1346

Synonym: CYN 154806 TFA

Target: Somatostatin

Panomifene TFA

Cat.No: T33876L1

Synonym: Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA

Target: Estrogen/progestogen Receptor

Camizestrant TFA

Cat.No: T11237L

Synonym: Camizestrant TFA(2222844-89-3 Free base),AZD-9833 TFA

Target: Estrogen Receptor/ERR

Cat.No: T8768

Synonym: HMTase Inhibitor IX TFA

Target: Histone Methyltransferase

Epithalon TFA (307297-39-8 free base)

Cat.No: TP1291

Synonym: Epithalon TFA

Target: Others

Cat.No: T13346L

Synonym: WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA

Target: Antifungal

Albiglutide TFA (782500-75-8 free base)

Cat.No: TP1796

Synonym: Albiglutide TFA

Target: Glucagon Receptor

CTAP(TFA） (103429-32-9 free base)

Cat.No: TP2050L

Synonym: CTAP(TFA）

Target: Opioid Receptor

Rotigaptide TFA(355151-12-1 free base)

Cat.No: T16790L

Synonym: Rotigaptide TFA

Target: Gap Junction Protein

Ezatiostat TFA

Cat.No: T5862

Synonym: TER199(free base),Ezatiostat TFA (free base),Ezatiostat,TLK199

Target: GST

Elarofiban TFA

Cat.No: T27250L

Synonym: Elarofiban TFA（198958-88-2 Free base）,RWJ-53308 TFA

Target: Integrin

(S,R,S)-AHPC TFA

Cat.No: T17927

Synonym: VH032-NH2 TFA,VHL ligand 1 TFA

Target: Others, Ligand for E3 Ligase

Atecegatran TFA

Cat.No: T30191L

Synonym: Atecegatran TFA(917904-13-3 Free base）,AR-H067637 TFA

Target: Others

FC131 TFA (606968-52-9 free base)

Cat.No: TP1348

Synonym: FC131 TFA

Target: HIV Protease, CXCR

Men 10376 TFA(135306-85-3,free)

Cat.No: TP1086

Synonym: Men 10376 TFA,Neurokinin-2 receptor antagonist TFA

Target: Neurokinin receptor

(Arg)9 TFA (143413-47-2 free base)

Cat.No: TP1079

Synonym: Nona-L-arginine (TFA),(Arg)9 TFA,Peptide R9 (TFA)

Target: Others

GsMTx4 TFA (1209500-46-8 free base)

Cat.No: TP1300

Synonym: GsMTx4 TFA

Target: Piezo Channel

DPDPE TFA (88373-73-3 free base)

Cat.No: TP2036L

Synonym: DPDPE TFA

Target: Opioid Receptor

Tolnapersine TFA

Cat.No: T68023L

Synonym: Tolnapersine TFA(70312-00-4 Free base)

Target: Dopamine Receptor, Adrenergic Receptor

Cat.No: T68166L

Synonym: Traxanox TFA(58712-69-9 Free base)

Target: Others

Tresperimus TFA

Cat.No: T34921L1

Synonym: Tresperimus TFA(160677-67-8 Free base)

Target: Others

DTP3 TFA (1809784-29-9 free base)

Cat.No: TP1430

Synonym: DTP3 TFA

Target: Others

Orbofiban TFA

Cat.No: T61345L

Synonym: Orbofiban TFA(163250-90-6 Free base)

Target: Integrin

[Met5]-Enkephalin, amide TFA

Cat.No: TP1254

Synonym: 5-Methionine-enkephalin amide (TFA)

Target: Opioid Receptor

Antennapedia Peptide TFA(188842-14-0 free base)

Cat.No: TP1318

Synonym: Antennapedia Peptide(TFA)

Target: Others

TRV-120027 TFA

Cat.No: TP2158

Synonym: TRV-120027 TFA (1234510-46-3 free base)

Target: RAAS, Arrestin

Lys-[Des-Arg9]Bradykinin,TFA

Cat.No: TP1918L

Synonym: Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa)

Target: Bradykinin Receptor

PAR-4 Agonist Peptide, amide TFA

Cat.No: TP1065

Synonym: PAR-4-AP (TFA),AY-NH2 (TFA)

Target: Protease-activated Receptor

Adrenocorticotropic Hormone (ACTH) (18-39), human TFA

Cat.No: TP1240

Synonym: CLIP (human) (TFA)

Target: Others

Cat.No: T36201L

Synonym: AZD5582 TFA（1258392-53-8 free base）

Target: Apoptosis, IAP

Laniquidar TFA

Cat.No: T64133L

Synonym: Laniquidar TFA(197509-46-9 Free base),R101933

Target: P-gp

Cat.No: T67972L

Synonym: Amp579 TFA(213453-89-5 Free base)

Target: Adenosine Receptor

Pam3CSK4 TFA (112208-00-1 free base)

Cat.No: TP1067

Synonym: Pam3CSK4 TFA,Pam3Cys-Ser-(Lys)4 TFA

Target: TLR

Oxamisole TFA

Cat.No: T33836L

Synonym: Oxamisole TFA（99258-56-7 Free base)

Target: Antiviral

Valorphin TFA(144313-54-2(free base))

Cat.No: T7666

Synonym: Valorphin TFA(144313-54-2(free bas))

Target: Others

CGRP (83-119), rat TFA

Cat.No: TP1200

Synonym: Calcitonin Gene Related Peptide(83-119), rat TFA

Target: Others

Cat.No: T28072L

Synonym: MLN-3897 TFA(1010731-97-1 Free base)

Target: CCR

Thalidomide-O-amido-C3-NH2 TFA

Cat.No: T7760

Synonym: Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA

Target: E3 Ligase Ligand-Linker Conjugate, Ligand for E3 Ligase

PKG inhibitor peptide TFA (82801-73-8 free base)

Cat.No: TP1523

Synonym: PKG inhibitor peptide TFA

Target: PKA

CaM kinase II inhibitor TFA salt

Cat.No: TP1216

Synonym: Autocamtide-2-related inhibitory peptide (TFA)

Target: CaMK

Cat.No: TP1433

Target: STAT

3X FLAG peptide TFA (402750-12-3 free base)

Cat.No: TP1275

Synonym: 3X FLAG peptide TFA

Target: Others

Cat.No: TP1947L

Target: Others

Alamandine TFA

Cat.No: T37496L

Target: RAAS

Leuphasyl TFA

Cat.No: T20435L

Target: Opioid Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T78500	α-Factor Mating Pheromone, yeast TFA Mating Factor α TFA
	α-Factor Mating Pheromone, yeast (TFA)为一来自S. cerevisiae的α细胞分泌的十三肽，通过Ste2p受体发挥作用。
T36295	Echistatin TFA
	Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4]. [1]. J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.[2]. ...
T35401	γ-Glu-Gly TFA
	γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid). It serves as an excitatory amino acid antagonist [1][2][3].
T75967	Bactenecin TFA
	Bactenecin TFA (Bactenecin, bovine TFA) 是一种从牛嗜中性粒细胞中分离出来的有效的含 12 个氨基酸的环状抗菌肽。Bactenecin TFA 抑制细菌和酵母菌 (bacteria 和 yeast) 的生长，并能杀死真菌红毛癣菌 (fungusTrichophyton rubrum)。Bactenecin TFA 增加了膜的通透性，抑制了假苹果芽孢杆菌 (B. pseudomallei) 的生长和生物膜的形成。
T75722	Chlorotoxin TFA
	Chlorotoxin TFA，一种从蝎子毒液中分离出的多肽，作为氯离子通道 (chloride channel) 的阻断剂，具备抗癌活性。
T75974	Cecropin A TFA
	Cecropin A TFA 是由 37 个氨基酸残基构成的线性抗菌肽，从 Hyalaphora cecropiapupae 得到，具有抗菌、抗炎和抗癌作用。
T75767	Parasin I TFA
	Parasin I (TFA) 是一种含有19个氨基酸残基的多肽，源自鲶鱼皮肤中分离出的组蛋白H2A，具备抗菌功能。
T83693	Magainin 2 TFA MG2
	Magainin 2是一种从非洲爪蟾（X. laevis）皮肤中分离出的阳离子肽，具有宿主防御和抗菌活性。该化合物对细菌E. coli、K. pneumoniae、S. epidermidis、S. aureus及真菌C. albicans表现出活性（MICs分别为5、10、10、50和80 µg/ml）。Magainin 2（20 µM）能降低猕猴桃花粉的萌发率和平均管长。在被单纯疱疹病毒1型（HSV-1）或2型（HSV-2）感染的Vero细胞中，它可减少病毒复制（EC50s分别为22.16和19.8 µM），同时不影响细胞活性，其50%细胞毒性浓度值（CC50）大于100 µM。
T75753	Magainin 1 TFA
	Magainin 1 TFA (Magainin I TFA) 是从 Xenopus laevis 皮肤中分离出的一种抗菌和两亲性肽。Magainin 1 TFA 对多种革兰氏阴性和革兰氏阳性细菌均表现出抗生素活性。
T75890	Conantokin G TFA
	Conantokin G TFA 是一种 17 个氨基酸的肽，是一种有效，选择性和竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。Conantokin G TFA 抑制鼠皮质神经元中NMDA 诱发的电流，IC50为 480 nM，具有神经保护作用。
T75743	HA Peptide TFA
	HA Peptide (TFA) 为源自人类流感血凝素 (HA) 的九氨基酸多肽，在细胞生物学与生物化学领域内广泛应用于目标蛋白的分离、纯化、检测及追踪。
T73764	L-Palmitoylcarnitine TFA
	L-Palmitoylcarnitine TFA 是一种长链酰基肉碱和脂肪酸代谢产物，在缺血期间积聚于肌膜并扰乱膜脂环境。L-Palmitoylcarnitine TFA 通过与Kir6.2的相互作用抑制KATP 通道活性，而不影响单通道电导。
T76027	β-Endorphin, equine TFA
	β-Endorphin, equine TFA，是具备强效亲和力于μ和δ阿片受体(μ/δ opioid receptors)的内源性阿片类多肽，主要功能包括止痛。
T61171	Cyclo(his-pro) TFA
	Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the blood-brain barrier and impact various inflammatory and stress responses [1, 2].
T4643	TFAP N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide	COX; Endogenous Metabolite	Immunology/Inflammation; Metabolism; Neuroscience
	TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) 是环氧酶 1 的一种选择性抑制剂，IC50值为 0.8 μM。
T19316	Ethyl oleate	Others	Others
	Ethyl oleate 是由油酸和乙醇的缩合形成的脂肪酸酯。它是纳米结构脂质载体 (NLC) 中的液体脂质成分。其中 NLC 是一种口服有活性的反式阿魏酸的给药载体。

天然产物

α-Factor Mating Pheromone, yeast TFA

Cat.No: T78500

Synonym: Mating Factor α TFA

Echistatin TFA

Cat.No: T36295

γ-Glu-Gly TFA

Cat.No: T35401

Bactenecin TFA

Cat.No: T75967

Chlorotoxin TFA

Cat.No: T75722

Cecropin A TFA

Cat.No: T75974

Parasin I TFA

Cat.No: T75767

Magainin 2 TFA

Cat.No: T83693

Synonym: MG2

Magainin 1 TFA

Cat.No: T75753

Conantokin G TFA

Cat.No: T75890

HA Peptide TFA

Cat.No: T75743

L-Palmitoylcarnitine TFA

Cat.No: T73764

β-Endorphin, equine TFA

Cat.No: T76027

Cyclo(his-pro) TFA

Cat.No: T61171

Cat.No: T4643

Synonym: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide

Target: COX, Endogenous Metabolite

Cat.No: T19316

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02530	Tissue Factor Protein, Human, Recombinant (His) CD142,coagulation factor III (thromboplastin, tissue factor)...	Human	HEK293
	Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemostatic and inflammatory processes. Activated monocytes present in the liver increase expression of tissue factor, and while accumulating in the organ they can intensify inflammation. Tissue factor is the protein that activates the blood clotting system by binding to, and activating...
TMPK-00993	Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His) Thromboplastin,CD142,TF,FLJ17960,TFA,F3,Coagulation...	Canine	HEK293
	Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.
TMPY-06957	Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated TFA,coagulation factor 3,coagulation factor III,CD1...	Human	HEK293
	Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemostatic and inflammatory processes. Activated monocytes present in the liver increase expression of tissue factor, and while accumulating in the organ they can intensify inflammation. Tissue factor is the protein that activates the blood clotting system by binding to, and activating...
TMPY-02537	Tissue Factor Protein, Human, Recombinant (hFc) coagulation factor III,coagulation factor III (thromboplasti...	Human	HEK293
	Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemostatic and inflammatory processes. Activated monocytes present in the liver increase expression of tissue factor, and while accumulating in the organ they can intensify inflammation. Tissue factor is the protein that activates the blood clotting system by binding to, and activating...
TMPY-05083	Tissue Factor Protein, Human, Recombinant (aa 1-295, His) coagulation factor 3,TF,TFA,coagulation factor III,...	Human	Baculovirus-Insect Cells
	Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemostatic and inflammatory processes. Activated monocytes present in the liver increase expression of tissue factor, and while accumulating in the organ they can intensify inflammation. Tissue factor is the protein that activates the blood clotting system by binding to, and activating...
TMPY-02949	AP2 Gamma/TFAP2C Protein, Human, Recombinant (His) ERF1,hAP-2g,transcription factor AP-2 gamma (activating enha...	Human	E. coli
	TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2C may be prognostic indicators for patients with breast tumors. TFAP2C gene has been tested fo...
TMPH-02939	TFAM Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Required for accurate and efficient pr...
TMPH-01724	MRTFA Protein, Human, Recombinant (His & KSI)	Human	E. coli
	Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. MRTFA binds G-actin via its RPEL repeats, regulating activity of the MRTFA-SRF complex. Activ...

重组蛋白

Tissue Factor Protein, Human, Recombinant (His)

Cat.No: TMPY-02530

Species: Human

Expression System: HEK293

Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)

Cat.No: TMPK-00993

Species: Canine

Expression System: HEK293

Tissue Factor Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06957

Species: Human

Expression System: HEK293

Tissue Factor Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02537

Species: Human

Expression System: HEK293

Tissue Factor Protein, Human, Recombinant (aa 1-295, His)

Cat.No: TMPY-05083

Species: Human

Expression System: Baculovirus-Insect Cells

AP2 Gamma/TFAP2C Protein, Human, Recombinant (His)

Cat.No: TMPY-02949

Species: Human

Expression System: E. coli

TFAM Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02939

Species: Mouse

Expression System: E. coli

MRTFA Protein, Human, Recombinant (His & KSI)

Cat.No: TMPH-01724

Species: Human

Expression System: E. coli

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