|
TMPY-02846
|
CLPS Protein, Human, Recombinant (His)
colipase, pancreatic
|
Human
|
Baculovirus Insect Cells
|
|
CLPS Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 11.5 kDa and the accession number is P04118. |
|
TMPY-04699
|
GAD65 Protein, Human, Recombinant (GST)
glutamate decarboxylase 2 (pancreatic islets and br...
|
Human
|
Baculovirus Insect Cells
|
|
GAD65 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 92.6 kDa and the accession number is Q05329. |
|
TMPJ-00743
|
PPY Protein, Human, Recombinant (His)
Pancreatic prohormone,Pancreatic polypepti...
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Human
|
HEK293 Cells
|
|
PPY belongs to the NPY family and is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia n... |
|
TMPY-00084
|
CLPS Protein, Rat, Recombinant (His)
colipase, pancreatic
|
Rat
|
HEK293 Cells
|
|
CLPS Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.9 kDa and the accession number is P17084. |
|
TMPY-01729
|
Carboxypeptidase A Protein, Human, Recombinant (His)
carboxypeptidase A1 (pancreatic),CPA
|
Human
|
HEK293 Cells
|
|
Carboxypeptidase A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is P15085. |
|
TMPY-00529
|
Alpha amylase/AMY2A Protein, Rhesus, Recombinant (hFc)
amylase, alpha 2A (pancreatic),AMY2B,α amylase/AMY2...
|
Rhesus
|
HEK293 Cells
|
|
Alpha amylase/AMY2A Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.8 kDa and the accession number is H9EX43. |
|
TMPY-03222
|
PNLIP Protein, Human, Recombinant (His)
PL,pancreatic lipase,PTL,PNLIPD
|
Human
|
HEK293 Cells
|
|
PNLIP is an enzyme that belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which a... |
|
TMPY-01362
|
Carboxypeptidase A Protein, Mouse, Recombinant (His)
Cpa,0910001L12Rik,carboxypeptidase A1 (pancreatic)
|
Mouse
|
HEK293 Cells
|
|
Carboxypeptidase A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is Q7TPZ8. |
|
TMPY-00252
|
PNLIPRP1 Protein, Rat, Recombinant (His)
pancreatic lipase-related protein 1
|
Rat
|
HEK293 Cells
|
|
PNLIPRP1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52 kDa and the accession number is P54316. |
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TMPY-03921
|
Alpha amylase/AMY2A Protein, Rhesus, Recombinant (His)
AMY2A,amylase, α 2A (pancreatic),α amylase/AMY2A,am...
|
Rhesus
|
HEK293 Cells
|
|
Alpha amylase/AMY2A Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.2 kDa and the accession number is H9EX43. |
|
TMPY-03182
|
PLRP2 Protein, Human, Recombinant (His)
PLRP2,pancreatic lipase-related protein 2
|
Human
|
Baculovirus Insect Cells
|
|
Galactolipase, also known as PNLIPRP2, is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on monoglycerides, phospholipids and galactolipids. It also hydrolyses milk fat with a lower catalytic efficiency. The expressed galactolipase shows a lipolytic activity that is, however, only marginally dependent on the presence of colipase. The lipolytic activity of pancreatic extracts and human pancreatic juice on Labraso... |
|
TMPY-03808
|
PNLIPRP1 Protein, Human, Recombinant (His)
pancreatic lipase-related protein 1,PLRP1
|
Human
|
HEK293 Cells
|
|
PNLIPRP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.4 kDa and the accession number is AAH25784.1. |
|
TMPY-03107
|
Alpha amylase/AMY2A Protein, Human, Recombinant (His)
amylase, α 2A (pancreatic),amylase, alpha 2A (p...
|
Human
|
HEK293 Cells
|
|
Alpha amylase/AMY2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is P04746. |
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TMPY-00340
|
Beta Amylase/AMY2B Protein, Human, Recombinant (hFc)
β Amylase/AMY2B,AMY2,HXA,amylase, α 2B (pancreatic)...
|
Human
|
HEK293 Cells
|
|
Beta Amylase/AMY2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.4 kDa and the accession number is P19961-1. |
|
TMPY-00503
|
Beta Amylase/AMY2B Protein, Human, Recombinant (His)
AMY2,amylase, alpha 2B (pancreatic),β Amylase/AMY2B...
|
Human
|
HEK293 Cells
|
|
Beta Amylase/AMY2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is P19961-1. |
|
TMPY-03180
|
Ribonuclease A Protein, Human, Recombinant (His)
RNS1,ribonuclease, RNase A family, 1 (pancreatic),R...
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Human
|
HEK293 Cells
|
|
RNase A, also known as ribonuclease A and RNASE1, belongs to ribonuclease A superfamily. It is a pancreatic-type of secretory ribonuclease. RNase A is a basic protein and its many positive charges are consistent with its binding to RNA (a poly-anion). More generally, RNase A is unusually polar or, rather, unusually lacking in hydrophobic groups, especially aliphatic ones. As an endonuclease, RNase A cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) ... |
|
TMPY-01590
|
GAD65 Protein, Mouse, Recombinant (His & GST)
glutamate decarboxylase 2 (pancreatic islets and br...
|
Mouse
|
Baculovirus Insect Cells
|
|
GAD65 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 93 kDa and the accession number is P48320. |
|
TMPY-03515
|
GAD65 Protein, Mouse, Recombinant
glutamate decarboxylase 2 (pancreatic islets and br...
|
Mouse
|
Baculovirus Insect Cells
|
|
GAD65 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 65.4 kDa and the accession number is P48320. |
|
TMPJ-00733
|
SPINK1 Protein, Human, Recombinant (His)
PSTI,Pancreatic Secretory Trypsin Inhibitor,TATI,Se...
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Human
|
HEK293 Cells
|
|
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). Recombinant SPINK1 protein (rSPINK1) stimulated cell proliferation in benign RWPE ... |
|
TMPJ-01108
|
SMAD4 Protein, Human, Recombinant (His)
DPC4,SMAD 4,Deletion Target in Pancreatic Carcinoma...
|
Human
|
E. coli
|
|
SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain. It is the component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. SMAD4 promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. SMAD4 may act as a tumo... |
|
TMPY-03221
|
Intrinsic Factor Protein, Human, Recombinant (His)
IF,IFMH,gastric intrinsic factor (vitamin B synthesis),INF,T...
|
Human
|
HEK293 Cells
|
|
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to... |
|
TMPY-01897
|
PRSS3 Protein, Human, Recombinant (His)
PRSS4,TRY4,TRY3,RP11-176F3.3,T9,MTG,protease, serine 3
|
Human
|
HEK293 Cells
|
|
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ... |
|
TMPY-03353
|
CEL Protein, Mouse, Recombinant (His)
1810036E18Rik,carboxyl ester lipase,BAL
|
Mouse
|
Baculovirus Insect Cells
|
|
CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL c... |
|
TMPH-02823
|
Peptide YY/PYY Protein, Mouse, Recombinant (GST)
|
Mouse
|
E. coli
|
|
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. |
|
TMPY-02640
|
FAM3B Protein, Human, Recombinant (hFc)
PANDER,ORF9,PRED44,C21orf11,C21orf76,42056,family with seque...
|
Human
|
HEK293 Cells
|
|
Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and beta- cells of pancreatic islets, insulin-secreting beta-TC3 cells, and glucagon-secreting alpha-TC cells. FAM3B causes apoptosis of beta-cells as assessed by electron microscopy, annexin Ⅴ fluorescent staining, and flow-cytometric terminal deoxynucleotidyl transferase-mediated dU... |
|
TMPY-04394
|
Glucokinase Protein, Human, Recombinant
glucokinase (hexokinase 4),HXKP,MODY2,FGQTL3,LGLK,HKIV,GLK,H...
|
Human
|
E. coli
|
|
Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but ... |
|
TMPJ-01196
|
ANGPTL8 Protein, Human, Recombinant (hFc)
βtrophin,Angiopoietin-like protein 8,Lipasin,Angptl8,Betatro...
|
Human
|
HEK293 Cells
|
|
The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proli... |
|
TMPJ-01028
|
Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag)
Claudin 18.2,CLDN18,Claudin-18,CLDN18.2,Claudin-18.2
|
Human
|
HEK293 Cells
|
|
Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. Human CLDN18.2 is highly expressed in a signifcant proportion of gastric and pancreat... |
|
TMPK-00820
|
AREG Protein, Human, Recombinant (hFc)
SDGF,AR,MGC13647,AREGB,CRDGF,Amphiregulin,AREG
|
Human
|
HEK293 Cells
|
|
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF‑κB signalling pathway in pancreatic cancer cells. |
|
TMPH-00661
|
Ecotin Protein, E. coli O127:H6, Recombinant (His & Myc)
eco,Ecotin
|
E. coli
|
E. coli
|
|
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. |
|
TMPJ-00190
|
CD38 Protein, Mouse, Recombinant (hFc)
ADP-ribosyl cyclase 1,cyclic ADP-ribose hydrolase,T10,CD38
|
Mouse
|
HEK293 Cells
|
|
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Th... |
|
TMPJ-00474
|
CPA1 Protein, Human, Recombinant (His)
CPA,Carboxypeptidase A1,CPA1
|
Human
|
HEK293 Cells
|
|
Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. It has a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 cleaves the C-terminal amide or ester bond of peptides and involves in zymogen inhibition. Three different forms of hu... |
|
TMPH-02643
|
Enteropeptidase Protein, Mouse, Recombinant (His & Myc)
Serine protease 7,Prss7,Transmembrane protease serine 15,Ent...
|
Mouse
|
HEK293 Cells
|
|
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. |
|
TMPY-02480
|
Chymotrypsin C Protein, Human, Recombinant (His)
ELA4,CLCR,chymotrypsin C (caldecrin)
|
Human
|
HEK293 Cells
|
|
Chymotrypsin C (abbreviated for CTRC), also known as caldecrin or elastase4, is a digestive enzyme of the peptidase S1 family. This enzyme is synthesized as an inactivate chymotrypsinogen. On cleavage by trypsin into two parts that activate each other by removing two small peptides in a trans-proteolysis, chymotrypsin C produced. N-linked glycosylation of human CTRC is required for efficient folding and secretion, however, the N-linked glycan is unimportant for enzyme activity or inhibitor bindi... |
|
TMPY-04075
|
CLIC1 Protein, Human, Recombinant (His)
NCC27,G6,chloride intracellular channel 1
|
Human
|
E. coli
|
|
Members of the CLIC family are largely soluble proteins that possess the intriguing property of spontaneous insertion into phospholipid bilayers to form integral membrane ion channels. Chloride intracellular channel 1 (CLIC1), a newly discovered member of the chloride channel protein family, has been implicated in multiple human cancers. CLIC1 is a Chloride Intracellular Ion Channel protein that exists either in a soluble state in the cytoplasm or as a membrane bound protein. CLIC1 acts as a put... |
|
TMPH-01852
|
Peptide YY/PYY Protein, Human, Recombinant (GST)
|
Human
|
E. coli
|
|
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Peptide YY/PYY Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.1 kDa and the accession number is P10082. |
|
TMPH-01400
|
GPD2 Protein, Human, Recombinant (His & Myc)
|
Human
|
E. coli
|
|
Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device. GPD2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 81.4 kDa and the accession number is P43304. |
|
TMPH-01767
|
NPY2R Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. NPY2R Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 48.8 kDa and the accession number is P49146. |
|
TMPK-00865
|
TM4SF1 Protein-VLP, Human, Recombinant
TAAL6,L6,H-L6,M3S1
|
Human
|
HEK293 Cells
|
|
Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis. |
|
TMPY-02602
|
PTPMT1 Protein, Human, Recombinant (His)
protein tyrosine phosphatase, mitochondrial 1,MOSP,FLJ46081,...
|
Human
|
E. coli
|
|
PTPMT1 (PTP localized to the Mitochondrion 1) is a member of the protein tyrosine phosphatase superfamily that is localized exclusively to the mitochondrion. It has been recently reported that PTPMT1 dephosphorylates phosphatidylglycerol phosphate, an essential intermediate of cardiolipin biosynthesis. PTPMT1 deficiency in mouse embryonic fibroblasts compromises mitochondrial respiration and results in abnormal mitochondrial morphology. Lipid analysis of PTPMT1-deficient fibroblasts reveals an a... |
|
TMPH-02323
|
SLC30A8 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.6 kDa and the accession number is Q8IWU4. |
|
TMPK-00721
|
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
Neurotactin,CXC3C,ABCD-3,Fkn,Fractalkine,NTT,Cx3cl1,SCYD1,Cx...
|
Mouse
|
HEK293 Cells
|
|
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma. |
|
TMPH-02979
|
SLC30A8 Protein, Mouse, Recombinant (His)
|
Mouse
|
E. coli
|
|
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.0 kDa and the accession number is Q8BGG0. |
|
TMPH-02644
|
Enteropeptidase Protein, Mouse, Recombinant (His & SUMO)
Tmprss15,Entk,Enterokinase,Serine protease 7,Prss7,Transmemb...
|
Mouse
|
E. coli
|
|
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. Enteropeptidase Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.0 kDa and the accession number is P97435. |
|
TMPK-00933
|
ADAM8/CD156a Protein, Mouse, Recombinant (His)
CD156a,MGC134985,ADAM 8,Ms2,Adam8
|
Mouse
|
HEK293 Cells
|
|
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/... |
|
TMPY-01847
|
REG3D Protein, Mouse, Recombinant (His)
Reg3d,regenerating islet-derived 3 delta,Ingaprp,MGC130575,I...
|
Mouse
|
HEK293 Cells
|
|
Regenerating islet-derived 3 delta (REG3D) is a member of the secreted Reg superfamily and contains one typical C-type lectin domain. Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on t... |
|
TMPJ-00602
|
CPA2 Protein, Human, Recombinant (His)
CPA2,Carboxypeptidase A2
|
Human
|
HEK293 Cells
|
|
Carboxypeptidase A2 (CPA) is a secreted pancreatic procarboxy-peptidase that cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreat... |
|
TMPH-01595
|
KMO Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable). |
|
TMPK-00073
|
TDGF1/Cripto Protein, Human, Recombinant (His)
TDGF1,Cripto,CR,CRGF
|
Human
|
HEK293 Cells
|
|
TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Cripto-1 is enriched in a subpopulation of embryonal, melanoma, prostate, and pancreatic cancer cells that possess stem-like characteristics. Therefore, Cripto-1 may play a role during developmental EMT, and it may also be involve... |
|
TMPJ-00815
|
FBPase1 Protein, Human, Recombinant (His, E. coli)
6-Bisphosphate 1-Phosphohydrolase 1,FBP1,FBP,FBPase 1,D-Fruc...
|
Human
|
E. coli
|
|
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young chi... |
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