app

JLK-6 是一种γ分泌酶抑制剂，选择性作用于 HEK293细胞的淀粉样β前体蛋白(APP)的γ-分泌酶裂解 APP，抑制 Aβ的生成，但对不 Notch 受体的裂解无影响。

δ-secretase inhibitor 11是一种分泌酶抑制剂，可用作 阿尔茨海默病（AD） 治疗转化开发的先导化合物。

APP-FUBINACA 是苯丙氨酸酰胺基吲唑-3-羧酰胺的衍生物，属于大麻素受体激动剂，具有神经刺激作用。

APP-CHMINACA is a synthetic cannabinoid (CB) featuring a 1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (CHMINACA) base. It displays a 10-fold greater affinity for the central CB1 receptor than that of JWH 018.

APP-018 (D-4F) 是18个D-氨基酸组成的模拟载脂蛋白 A-I (apoA-I) 的肽。它能够增强高密度脂蛋白 (HDL) 的抗炎活性，并且可以用于心血管疾病的研究。

APP669-711是淀粉样蛋白前体 (APP) 从669位到711位的氨基酸序列片段。APP669-711可用于检测大脑中的淀粉样蛋白沉积，是阿尔茨海默病 (AD) 研究的生物标志物。

Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).

β-Amyloid/A4 Protein Precusor (319-335) (APP (319-335)) 是 β-淀粉样蛋白/A4 蛋白前体 (APP) 的一段多肽。此片段能识别肝素酶不敏感的位点，该位点包含 APP 促神经细胞活性。

Lappaconitine ((+)-Lappaconitine) 是从高乌头中分离得到的一种天然产物，可用于缓解疼痛的研究。

Apparicine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125353。

Glucocapparin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125730。

4-O-Methylepisappanol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126375。

Sappanol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126391。

3'-Deoxy-4-O-methylepisappanol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126471。

Sappanone B 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126481。

Caesappanin C 是一种联苯二聚体，提取自印度尼西亚 Caesalpinia sappan L. 的心材中，具有刺激骨形成和再生的潜力。它在体外显示出对原代成骨细胞的强增殖刺激活性。

NEP(1-40), N-terminal uncapped 是 NEP(1-40) 的类似物，但其 N 端未进行乙酰化修饰。NEP(1-40) 是一种 Nogo-66 受体 (NgR) 的肽类拮抗剂。

D-NMAPPD ((1R,2R)-B13) 是一种酸性神经酰胺酶抑制剂，也是神经酰胺类似物，具有潜在的抗增殖活性，可调节人黑色素瘤细胞中神经酰胺信号传导。D-NMAPPD 可用于研究结肠癌。

Lappaconitine HCl is a centrally acting non-opioid analgesic and class-I antiarrhythmic. It acts by binding to the site-2 receptor and irreversibly blocking hH1 sodium channels.

SMAPP1 is an activator of protein phosphatase 1 (PP1). SMAPP1 induces PP1 activity in vitro and activates latent HIV-1 provirus in cultured and primary T cells.

Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) 衍生自去甲二萜生物碱。

KQMEEEAVRLFIEWLKNGGPSSGAPPPS is a Exendin-4 peptide derivative. Exendin-4 is a pure GLP-1 receptor agonist. Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may relates to dual GLP-1/glucagon receptor agonists. Their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as for reduction of excess food intake. These dual GLP-1/glucagon receptor agonists show reduced activity on the GIP receptor to reduce the risk of hypoglycemia[1]. [1]. US20150315260 A1

D-erythro-MAPP (D-e-MAPP) 是神经酰胺酶抑制剂，是一种神经酰胺类似物，具有潜在的抗癌活性。

Synthetic and natural alkyl phosphates, also known as phosphoantigens, stimulate the proliferation of γδ-T lymphocytes. Isopentenyl pyrophosphate, and related derivatives including (E)-hydroxy-dimethyl-allyl pyrophosphate ((E)-HDMAPP), are particularly effective activators of γδ-T cells. (E)-C-HDMAPP is the pyrophosphonate form of (E)-HDMAPP. The pyrophosphonate moiety in (E)-C-HDMAPP is much less susceptible to chemical or enzymatic hydrolysis than its pyrophosphate counterpart. As a result, (E)-C-HDMAPP is much more stable in solution and in vascular circulation. (E)-C-HDMAPP possesses comparable activity to (E)-HDMAPP, which is the most potent of the isoprenoid phosphoantigens. (E)-C-HDMAPP stimulates the synthesis of tumor necrosis factor (TNF-α) by γδ-T lymphocytes with an IC50 value of 0.91 nM. (E)-C-HDMAPP also significantly increases the number of circulating γδ-T cells in vivo, in cynomolgus monkeys.