购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TRRAP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13851

Anti-TRRAP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TRRAP。Anti-TRRAP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-TRRAP Polyclonal Antibody

Anti-TRRAP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13851

Anti-TRRAP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TRRAP。Anti-TRRAP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-TRRAP Polyclonal Antibody is a Rabbit antibody targeting TRRAP. Anti-TRRAP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Horse,Sheep,Xenopus laevis)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nuclear
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The transcription factors c-Myc and E2F are involved in regulating cell cycle progression. Overexpression of c-Myc in certain cell types induces noncycling cells to enter the cell cycle via a mechanism involving E2F-1 (1). E2F-1 is thought to regulate c-Myc expression via interactions with the retinoblastoma protein (2). TRRAP (for transformation/transcription domain-associated protein) interacts specifically with both c-Myc and E2F-1. Expression of trans-activated mutant TRRAP inhibits the oncogenic transformation of both c-Myc and E2F-1, suggesting that TRRAP is required for these oncogenic transcription factor pathways (3). TRRAP shares homology with the ATM/PI 3-kinase family, and it is highly conserved in evolution (4,5).
抗原信息
免疫原
KLH conjugated synthetic peptide: human TRRAP
抗原种属
Human
基因名称
TRRAP
基因ID
8295
蛋白名称
Transformation/transcription domain-associated protein
Uniprot ID
Q9Y4A5
功能
TRRAP (TRansformation/tRanscription domain Associated Protein) is an adapter protein that is found in a number of multiprotein chromatin complexes with histone acetyltransferase (HAT) activity. These complexes include PCAF, TFTC-HAT, TIP60 HAT, STAGA, and BAF53 complexes. TRRAP is thought to be responsible for the concerted and context-dependent recruitment of these complexes to chromatin during transcription, replication and DNA repair. TRRAP plays a key role in transcriptional activation by c-Myc, p53/TP53, E2F1 and E2F4.
化学信息
分子量Theoretical: 438 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-TRRAP Polyclonal Antibody | purchase Anti-TRRAP Polyclonal Antibody | Anti-TRRAP Polyclonal Antibody cost | order Anti-TRRAP Polyclonal Antibody | Anti-TRRAP Polyclonal Antibody molecular weight