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Targets Recommended: AChR

317

抑制剂 & 化合物

52

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8

化合物库

162

重组蛋白

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Cat. No. Product Name
L2600 神经信号分子库

2540 compounds
2540 种CNS 相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2630 神经元分化化合物库

672 compounds
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发
L7400 钠通道分子库

118 compounds
118 种钠通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L1580 GPCR库Plus

338 compounds
338 种GPCR 靶向、结构新颖的化合物;
L1500 GPCR靶点分子库

1940 compounds
1940 种与 G 蛋白及其耦联受体相关的生物活性小分子化合物,所有小分子都具有良好的生物和药理活性,部分是 FDA 批准的上市药物;
L7700 神经再生化合物库

524 compounds
524 种神经再生相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2540 肠道微生物代谢化合物库

607 compounds
607 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选;
L2610 神经递质受体化合物库

1513 compounds
1513 种与神经递质受体相关的化合物,用于高通量、高内涵筛选;

化合物库

神经信号分子库
Cat.No: L2600
Compounds: 2540
神经元分化化合物库
Cat.No: L2630
Compounds: 672
钠通道分子库
Cat.No: L7400
Compounds: 118
GPCR库Plus
Cat.No: L1580
Compounds: 338
GPCR靶点分子库
Cat.No: L1500
Compounds: 1940
神经再生化合物库
Cat.No: L7700
Compounds: 524
肠道微生物代谢化合物库
Cat.No: L2540
Compounds: 607
神经递质受体化合物库
Cat.No: L2610
Compounds: 1513
Cat. No. Product Name Target Signaling Pathways
T9787 suvn-911

AChR Neuroscience
SUVN-911 是高选择性的,大脑通透性的和口服有效的神经元烟碱乙酰胆碱 α4β2 受体拮抗剂,Ki 为 1.5 nM。SUVN-911显示出抗抑郁作用。
T9357 Ro 5212773

Epptb

Others Others
Ro 5212773 (Epptb) 是TAAR1的选择性拮抗剂(对于小鼠 TAAR1 的Ki= 0.9 nM),对其他 TAARs 没有显著影响。其中TAAR1 是一种 G 蛋白偶联受体 (GPCR),能够被内源性氨基酸代谢产物非选择性的激活。
T6617 Optovin

TRP/TRPV Channel Membrane transporter/Ion channel
Optovin 是可逆的光活化 TRPA1配体,可实现光介导的神经元兴奋。它通过与氧化还原敏感的半胱氨酸残基产生结构依赖性光化学反应激活 TRPA1。
T7899 VU0810464

Potassium Channel Membrane transporter/Ion channel
VU0810464 是一种选择性的非尿素蛋白门控的内向整流钾通道激活剂。 VU0810464对神经元 GIRK1/2和GIRK1/4 的EC50分别为165 nM 和720 nM。VU0810464具有脑部渗透性。
T5447 Anle138b

Beta Amyloid; Others Neuroscience; Others
Anle138b 是一种毒性低,口服生物利用度高,血脑屏障通透性好的低聚物聚集抑调节剂,可阻断朊病毒蛋白和 α-突触核蛋白病理性聚集的形成。它在体内强烈抑制低聚物积累、神经元变性和疾病进展。它阻断 Aβ 通道并挽救淀粉样变性小鼠模型的疾病表型。
T2164 Wiskostatin

Others Others
Wiskostatin 是神经元 Wiskott-Aldrich 综合征蛋白介导的肌动蛋白聚合的选择性抑制剂,能够不可逆的使细胞 ATP 水平快速下降。
T2022 CZC-54252

CZC54252,CZC 54252

LRRK2 Autophagy
CZC-54252 是一种选择性 LRRK2有效抑制剂,对野生型和 G2019S LRRK2的 IC50分别为 1.28 nM 和 1.85 nM。它具有神经保护活性,可减弱由 G2019S LRRK2 诱导的人神经元损伤 ,EC50约为 1 nM。
T5850 Benzamil

Benzamil (hydrochloride)

Na+/Ca2+ Exchanger; Sodium Channel Membrane transporter/Ion channel
Benzamil 是 Amiloride 类似物,是 Na+/Ca2+交换体抑制剂,抑制 TRPP3 介导的 Ca2+激活电流,IC50为 1.1 μM。它也是一种非选择性上皮钠通道 (ENaC) 阻滞剂,能增强肌源性血管收缩。
T21902 ML351

Lipoxygenase Metabolism
ML351 是一种高度特异的15-LOX-1抑制剂,其 IC50=200 nM。它对 T1D 非肥胖糖尿病小鼠模型的血糖异常和β细胞氧化应激有抑制作用。它对相关同工酶 (5-LOX、血小板 12-LOX、15-LOX-2、绵羊 COX-1 和人 COX-2) 表现出良好的选择性(>250倍)。
T15286 Flindokalner

BMS-204352

Potassium Channel Membrane transporter/Ion channel
Flindokalner (BMS-204352) 是一种钾离子通道调节剂。它是大电导钙激活 K 通道正向调节剂。它是在 HEK293 细胞中表达的所有神经元 Kv7通道亚型的正调节剂。它在 Kv7.1 通道 (Ki=3.7 μM) 处显示负调节活性,并充当 GABAA 受体的负调节剂。它在体内显示出抗焦虑功效。
T11095L DREADD agonist 21

5-HT Receptor; Adrenergic Receptor; AChR; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
DREADD agonist 21 是一种人毒蕈碱乙酰胆碱 M3 受体激动剂,EC50为 1.7 nM。
T3478 Ro 67-7476

GluR Neuroscience
Ro 67-7476 是mGluR1的正变位调节剂,能增强表达 rat mGluR1a 的 HEK293 细胞中谷氨酸诱导的钙释放,EC50为 60.1 nM。它是 P-ERK1/2 激动剂,可以在外源添加谷氨酸的情况下激活 ERK1/2 磷酸化 (EC50=163.3 nM)。
T4612 NS309

EGFR; Potassium Channel; HER Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
NS309 是选择性钙依赖性钾离子通道 SK/IK 的激活剂,在 BK 通道上没有激活作用。
T0946 Mepivacaine hydrochloride

Mepivacaine HCl,盐酸甲哌卡因

Sodium Channel Membrane transporter/Ion channel
Mepivacaine hydrochloride (Mepivacaine HCl) 是具有局部麻醉特性的酰胺衍生物。Mepivacaine hydrochloride 与神经元细胞膜上特定的电压门控钠离子通道结合,抑制钠离子内流和膜去极化。
T6697 TCID

UCH-L3 Inhibitor

DUB Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
TCID (UCH-L3 Inhibitor) 是一种有效的选择性神经元泛素 C 末端水解酶 L3 的 DUB 抑制剂,IC50为 0.6 μM。它对 L1 具有 125 倍的选择性,可减少脑干和脊髓原代神经元中的甘氨酸转运蛋白 GlyT2 泛素化。
T60080 TMPH

2,2,6,6-Tetramethylpiperidin-4-yl heptanoate

AChR Neuroscience
TMPH 是一种 nAChR 抑制剂,可抑制缺乏 α5、α6 或 β3 亚基的 nAChR。 TMPH 可用于关于 nAChR 功能障碍或神经系统疾病的研究。
T39202 CZC-54252 hydrochloride

LRRK2 Autophagy
CZC-54252 hydrochloride 是 LRRK2 的特异性抑制剂,对野生型和 G2019S LRRK2 的 IC50 分别为 1.85 nM 和 1.28 nM。 CZC-54252 hydrochloride 具有神经保护活性,可减轻 G2019S LRRK2 诱导的人类神经元损伤,EC50 为 1 nM。
T5827 BI-6C9

Apoptosis; Others; Mitochondrial Metabolism Apoptosis; Metabolism; Others
BI-6C9 是一种高特异性的 BH3 相互作用结构域抑制剂,可阻止线粒体外膜电位和线粒体分裂,并保护细胞免受线粒体凋亡诱导因子释放和不依赖 caspase 的细胞死亡。
T19659 Annaosanchun

雄甾-3,5,6三醇,YC6,YC-6,YC 6

Others; AMPK Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
Annaosanchun (YC-6) 有可能用于治疗急性缺血性中风(AIS)。
T0386L Ropivacaine

LEA-103 HCl,罗哌卡因

Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Ropivacaine (LEA-103 HCl) 是有效的钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂,在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
T19062 Sulforhodamine 101

磺基罗丹明101,磺基罗丹明 101,SR101

Others Others
Sulforhodamine 101 (SR101) 是一种两性罗丹明红色荧光染料 (excitation/emission: 586/605 nm),常用于神经元形态的研究,并作为星形胶质细胞的细胞类型选择性荧光标记物,在体内和切片制备中都有应用。
T6488 Epinastine hydrochloride

Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat

5-HT Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Epinastine hydrochloride (WAL-801CL HCl) 是抗组胺剂和肥大细胞稳定剂,是一种可口服的选择性组胺 H1 受体拮抗剂,可抑制 IL-8 释放,具有抗过敏作用。
T0386 Ropivacaine hydrochloride

盐酸罗哌卡因,Ropivacaine monohydrochloride

Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) 是钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine hydrochloride 也是 K2P(双孔钾通道)TREK-1的抑制剂。在动物实验模型中,Ropivacaine hydrochloride 可用于神经性疼痛的缓解。
T1567 Olanzapine

LY170053,奥氮平

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR GPCR/G Protein; Neuroscience
Olanzapine (LY170053) 是一种非典型抗精神病药,目前用于治疗精神分裂症和双相情感障碍。
T7002 Trihexyphenidyl hydrochloride

Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride,盐酸苯海索

AChR Neuroscience
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) 是一种抗毒蕈碱类的抗帕金森病药物,结合至M1毒蕈碱受体。
T11571 HLY78

4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) 是 Wnt/β-catenin 信号通路的激活剂,通过靶向通道中 Axin 的 DIX 域,增强 Axin-LRP6 交联,诱导 Wnt 信号转导。
T0499 Oxybenzone

二苯酮-3,KAHSCREEN BZ-3,Benzophenone 3,Eusolex 4360,紫外线吸收剂UV-9,Escalol 567

Apoptosis; Retinoid Receptor; Autophagy Apoptosis; Autophagy; Metabolism
Oxybenzone (Eusolex 4360) 是晒黑和皮肤保护剂中常用的紫外线过滤剂。它是二苯甲酮的衍生物,用作破坏内分泌的化学物质,可穿透胎盘和血脑屏障。它损害自噬,改变表观遗传状态并破坏凋亡神经元细胞中的类维生素 X 受体信号传导。
T4358 Vosilasarm

Testolone,RAD140

Androgen Receptor Endocrinology/Hormones
Testolone 是一种有效的、非甾体的、具有口服活性的、选择性雄激素受体调节剂 (SARM),Ki 为 7 nM。它对雄激素受体的选择性比其他类固醇激素核受体高。
T0031L Ziprasidone hydrochloride

盐酸齐拉西酮,齐拉西酮盐酸盐,CP-88059 hydrochloride,CP-88059,Ziprasidone HCl

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Norepinephrine; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Ziprasidone hydrochloride (CP-88059 hydrochloride) 是一种联合 5-HT(5-羟色胺)和多巴胺受体拮抗剂,具有抗精神病活性的强效作用。它也是去甲肾上腺素再摄取抑制剂。
T6645 Ropivacaine hydrochloride monohydrate

Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,盐酸罗哌卡因,盐酸罗哌卡因一水合物,LEA-103 HCl

Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Ropivacaine hydrochloride monohydrate (LEA-103 HCl) 是钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine HCl monohydrate 也是 K2P(双孔钾通道)TREK-1的抑制剂。在动物实验模型中,Ropivacaine HCl monohydrate 可用于神经性疼痛的缓解。
T7474 7-Nitroindazole

NOS Immunology/Inflammation
7-Nitroindazole 是一种具有抗损伤及心血管作用的选择性nNOS 抑制剂,也是评价一氧化氮在中枢神经系统中生物学效应的有效工具。
T23446 TCS 2210

Others Others
TCS 2210是间充质干细胞中神经元分化的诱导剂,并增加神经元标志物β-III 管蛋白的表达和神经元特异性烯醇酶的表达。
T5170 KHS101 hydrochloride

盐酸KHS101

FGFR; Microtubule Associated Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
KHS101 hydrochloride 能够选择性的诱导神经元分化表型,能够与转化酸性含螺旋蛋白发生相互作用。
T12738L1 Rivanicline 2HCl

Rivanicline 2HCl(15585-43-0 Free base)

AChR Neuroscience
Rivanicline 2HCl 是一种选择性神经元烟碱受体(neuronal nicotinic receptor) 的抑制剂,对α4β2 亚型的亲和力较高。
T19892 BSBM7

N,N'-二(苄氧羰基)-L-胱氨酸

Beta Amyloid Neuroscience
BSBM7 是 Aβ 聚集和神经元毒性的抑制剂。
T16288 Neuropathiazol

Others Others
Neuropathiazol 引起成年海马神经祖细胞的神经元分化。
T25450 GGTI 2147

GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147

NF-κB; Rho Cell Cycle/Checkpoint; NF-κB
GGTI 2147 降低 Rac1 活性,下调 p65 的表达,改善 OGD/R 诱导的神经元凋亡。
T16287 Neurodazine

DNA Methyltransferase Chromatin/Epigenetic
Neurodazine 是一种神经性诱导剂,可促进多能细胞分化为神经元细胞。Neurodazine 通过激活 Wnt 和 Shh 信号传导促进分化。
T12017 Methyllycaconitine citrate

MLA

AChR Neuroscience
Methyllycaconitine citrate (MLA) 是一种可穿过血脑屏障的 α7 神经元烟碱乙酰胆碱受体(α7nAChR)拮抗剂,可用于研究神经系统疾病。
T2166 TWS119

GSK-3; Autophagy Autophagy; PI3K/Akt/mTOR signaling; Stem Cells
TWS119 是一种GSK-3β特异性抑制剂,IC50值为 30 nM,它可激活 wnt/β-catenin 信号通路,能够诱导神经元分化。
T15196 EC23

BASF-46928,AGN 190205

Others Others
EC23 (AGN 190205) 是一种稳定的合成类视黄醇类似物,能够促使神经元分化。
T14912 CD3254

Retinoid Receptor Metabolism
CD3254 是一种具有选择性和强效性的类视黄醇 X 受体 (RXR) 激动剂,可抑制伴有OGD/再氧合的神经元细胞死亡。
T72063 PDCD4-IN-1

PDCD4-IN-1是一种 PDCD4抑制剂(Kd :350 nM),可促进海马神经元细胞 HT-22 中 BDNF 表达。
T0222 Proparacaine hydrochloride

盐酸丙美卡因,Proparacaine HCl,Proxymetacaine Hydrochloride

Apoptosis; Sodium Channel Apoptosis; Membrane transporter/Ion channel
Proparacaine hydrochloride (Proparacaine HCl) 是 Lidocaine 的衍生物,具有糖皮质激素样活性和免疫调节作用。
T1880 P7C3

Others Others
P7C3 是一种 aminopropyl carbazole 类化合物,具有口服活性,可透过血脑屏障,具有神经保护作用。它可用于神经退行性疾病,如帕金森病的研究。
T10813 Cilobradine hydrochloride

DK-AH 269

HCN Channel Membrane transporter/Ion channel
Cilobradine hydrochloride (DK-AH 269) 是一种 HCN 通道阻断剂。
T8725 A 582941 HCl (848591-90-2(free base))

AChR Neuroscience
A 582941 HCl (848591-90-2(free base)) 是一种具有广谱认知增强特性的 alpha7 神经元烟碱受体激动剂。
T0287 Hexamethonium Bromide

Gangliostat,溴化六甲铵,Simpatoblock,六甲溴铵,Hexamethonium Dibromide

Apoptosis; Dopamine Receptor; AChR Apoptosis; GPCR/G Protein; Neuroscience
Hexamethonium Bromide (Hexamethonium Dibromide) 是神经节中神经元型烟碱型 AChR 的特异性拮抗剂。在自发性高血压动物模型中,它能降低其交感神经活动和血压。
T6504 Flupirtine maleate

Katadolon maleate,氟吡啶马来酸,马来酸氟吡汀

Potassium Channel; NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
Flupirtine maleate (Katadolon maleate) 是可透过血脑屏障的、具有口服活性的非阿片类化合物。它是间接 NMDAR 拮抗剂,可用于缓解疼痛的研究,具有神经保护特性。
T28544 RL648_81

Potassium Channel Membrane transporter/Ion channel
RL648_81 是 KCNQ2/3 通道的选择性激活剂 (EC50 = 190 nM)。 RL648_81 可用于神经元过度兴奋性神经系统疾病的研究。

化合物

suvn-911
Cat.No: T9787
Synonym:
Target: AChR
Ro 5212773
Cat.No: T9357
Synonym: Epptb
Target: Others
Optovin
Cat.No: T6617
Synonym:
Target: TRP/TRPV Channel
VU0810464
Cat.No: T7899
Synonym:
Target: Potassium Channel
Anle138b
Cat.No: T5447
Synonym:
Target: Beta Amyloid, Others
Wiskostatin
Cat.No: T2164
Synonym:
Target: Others
CZC-54252
Cat.No: T2022
Synonym: CZC54252,CZC 54252
Target: LRRK2
Benzamil
Cat.No: T5850
Synonym: Benzamil (hydrochloride)
Target: Na+/Ca2+ Exchanger, Sodium Channel
ML351
Cat.No: T21902
Synonym:
Target: Lipoxygenase
Flindokalner
Cat.No: T15286
Synonym: BMS-204352
Target: Potassium Channel
DREADD agonist 21
Cat.No: T11095L
Synonym:
Target: 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor
Ro 67-7476
Cat.No: T3478
Synonym:
Target: GluR
NS309
Cat.No: T4612
Synonym:
Target: EGFR, Potassium Channel, HER
Mepivacaine hydrochloride
Cat.No: T0946
Synonym: Mepivacaine HCl,盐酸甲哌卡因
Target: Sodium Channel
TCID
Cat.No: T6697
Synonym: UCH-L3 Inhibitor
Target: DUB
TMPH
Cat.No: T60080
Synonym: 2,2,6,6-Tetramethylpiperidin-4-yl heptanoate
Target: AChR
CZC-54252 hydrochloride
Cat.No: T39202
Synonym:
Target: LRRK2
BI-6C9
Cat.No: T5827
Synonym:
Target: Apoptosis, Others, Mitochondrial Metabolism
Annaosanchun
Cat.No: T19659
Synonym: 雄甾-3,5,6三醇,YC6,YC-6,YC 6
Target: Others, AMPK
Ropivacaine
Cat.No: T0386L
Synonym: LEA-103 HCl,罗哌卡因
Target: Potassium Channel, Sodium Channel
Sulforhodamine 101
Cat.No: T19062
Synonym: 磺基罗丹明101,磺基罗丹明 101,SR101
Target: Others
Epinastine hydrochloride
Cat.No: T6488
Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat
Target: 5-HT Receptor, Histamine Receptor
Ropivacaine hydrochloride
Cat.No: T0386
Synonym: 盐酸罗哌卡因,Ropivacaine monohydrochloride
Target: Potassium Channel, Sodium Channel
Olanzapine
Cat.No: T1567
Synonym: LY170053,奥氮平
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR
Trihexyphenidyl hydrochloride
Cat.No: T7002
Synonym: Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride,盐酸苯海索
Target: AChR
HLY78
Cat.No: T11571
Synonym: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine
Target: Wnt/beta-catenin
Oxybenzone
Cat.No: T0499
Synonym: 二苯酮-3,KAHSCREEN BZ-3,Benzophenone 3,Eusolex 4360,紫外线吸收剂UV-9,Escalol 567
Target: Apoptosis, Retinoid Receptor, Autophagy
Vosilasarm
Cat.No: T4358
Synonym: Testolone,RAD140
Target: Androgen Receptor
Ziprasidone hydrochloride
Cat.No: T0031L
Synonym: 盐酸齐拉西酮,齐拉西酮盐酸盐,CP-88059 hydrochloride,CP-88059,Ziprasidone HCl
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Norepinephrine, Histamine Receptor
Ropivacaine hydrochloride monohydrate
Cat.No: T6645
Synonym: Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,盐酸罗哌卡因,盐酸罗哌卡因一水合物,LEA-103 HCl
Target: Potassium Channel, Sodium Channel
7-Nitroindazole
Cat.No: T7474
Synonym:
Target: NOS
TCS 2210
Cat.No: T23446
Synonym:
Target: Others
KHS101 hydrochloride
Cat.No: T5170
Synonym: 盐酸KHS101
Target: FGFR, Microtubule Associated
Rivanicline 2HCl
Cat.No: T12738L1
Synonym: Rivanicline 2HCl(15585-43-0 Free base)
Target: AChR
BSBM7
Cat.No: T19892
Synonym: N,N'-二(苄氧羰基)-L-胱氨酸
Target: Beta Amyloid
Neuropathiazol
Cat.No: T16288
Synonym:
Target: Others
GGTI 2147
Cat.No: T25450
Synonym: GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147
Target: NF-κB, Rho
Neurodazine
Cat.No: T16287
Synonym:
Target: DNA Methyltransferase
Methyllycaconitine citrate
Cat.No: T12017
Synonym: MLA
Target: AChR
TWS119
Cat.No: T2166
Synonym:
Target: GSK-3, Autophagy
EC23
Cat.No: T15196
Synonym: BASF-46928,AGN 190205
Target: Others
CD3254
Cat.No: T14912
Synonym:
Target: Retinoid Receptor
PDCD4-IN-1
Cat.No: T72063
Synonym:
Target:
Proparacaine hydrochloride
Cat.No: T0222
Synonym: 盐酸丙美卡因,Proparacaine HCl,Proxymetacaine Hydrochloride
Target: Apoptosis, Sodium Channel
P7C3
Cat.No: T1880
Synonym:
Target: Others
Cilobradine hydrochloride
Cat.No: T10813
Synonym: DK-AH 269
Target: HCN Channel
A 582941 HCl (848591-90-2(free base))
Cat.No: T8725
Synonym:
Target: AChR
Hexamethonium Bromide
Cat.No: T0287
Synonym: Gangliostat,溴化六甲铵,Simpatoblock,六甲溴铵,Hexamethonium Dibromide
Target: Apoptosis, Dopamine Receptor, AChR
Flupirtine maleate
Cat.No: T6504
Synonym: Katadolon maleate,氟吡啶马来酸,马来酸氟吡汀
Target: Potassium Channel, NMDAR, iGluR
RL648_81
Cat.No: T28544
Synonym:
Target: Potassium Channel
Cat. No. Product Name Target Signaling Pathways
T9076 Spinosad

Others Others
Spinosad 是在土壤细菌 S. spinosa 中发现的一种杀虫剂,是大环内酯多杀菌素 A 和多杀菌素 D 的混合物,可作为昆虫烟碱乙酰胆碱酯酶受体 (nAChRs) 的激动剂。它具有优良的环境和哺乳动物毒理学特征,以及杀灭幼虫的活性。
T0853 Adenosine

腺苷,D-Adenosine,Adenine riboside

Apoptosis; Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Adenosine (D-Adenosine) 是一种核糖核苷,由与核糖结合的腺嘌呤组成,具有血管扩张、抗心律失常和镇痛作用。
TN6714 Geranylgeraniol

FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095

Apoptosis Apoptosis
Geranylgeraniol (FT0626663) 是一种类异戊二烯,存在于水果、蔬菜和谷物中,包括大米。 Geranylgeraniol (FT0626663) 抑制生长并诱导各种肿瘤细胞的凋亡。 Geranylgeraniol (FT0626663) 保护单核细胞免受他汀类药物诱导的细胞毒性并抑制分枝杆菌的生长。
TN6924 Anhydrosafflor yellow B

(2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,脱水红花黄色素B,AHSYB

Others Others
Anhydrosafflor yellow B ((2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1) 是从红花中分离出来的,可抑制 ADP 诱导的血小板聚集,在体外表现出显着的抗氧化作用,并对 H2O2 诱导的细胞毒性具有一定的活性。
TN1038 Galgravin

Apoptosis Apoptosis
Galgravin 是望春花中的一种天然产物,具有抗炎和体外细胞毒活性,能诱导白血病细胞凋亡。
T5S0733 Picroside III

Others Others
Picroside III(胡黄连苷 III)是一种环烯醚萜苷,分离自传统中药胡黄连中。
T13923 Thiamine nitrate

硝酸硫胺,Vitamin B1 nitrate

Others Others
Thiamine nitrate (Vitamin B1 nitrate) 是必不能够少的维生素,能够提高正常的神经元活性。
T6S0654 Isocorynoxeine

7-Isocorynoxeine,异去氢钩藤碱

5-HT Receptor GPCR/G Protein; Neuroscience
Isocorynoxeine (7-Isocorynoxeine) 是钩藤中的一种生物碱,剂量依赖性抑制5-HT2A 受体介导的电流反应,IC50为 72.4 μM。
T3931 Isobavachin

Others Others
Isobavachin 是一种分离自Psoralea morisiana 中的抗氧化剂,在A 环的8号位置有一个prenyl 基团,具有潜在的促进神经元的分化和其蛋白异戊烯化作用。
T5287 N-Acetyl-L-aspartic acid

AC-ASP-OH,N-Acetylaspartic acid,N-乙酰-L-天门冬氨酸

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-aspartic acid (AC-ASP-OH) 是天冬氨酸的衍生物, 是由氨基酸天冬氨酸和乙酰辅酶 A 在神经元中合成的。
T6S0659 Rhynchophylline

钩藤碱,Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin

Calcium Channel; NF-κB Membrane transporter/Ion channel; Metabolism; NF-κB
Rhynchophylline (Mitrinermine) 是一种生物碱类化合物,从钩藤中分离得到,具有很高的生物活性,被广泛用于抗炎、神经保护等方面的研究。
T0268 Lobeline hydrochloride

盐酸洛贝林,α-Lobeline hydrochloride,L-Lobeline hydrochloride

AChR Neuroscience
Lobeline hydrochloride (α-Lobeline hydrochloride) 是一种烟碱样受体激动剂,是神经元烟碱受体α3β2和α4β2拮抗剂。
T8852 tubuloside B

Apoptosis; Others Apoptosis; Others
Tubuloside B 是可从管花肉苁蓉茎中分离出的一种天然产物,具有抗氧化活性,可抑制TNFα 诱导的细胞凋亡。
T64353 4-tert-Octylphenol

Endogenous Metabolite Metabolism
4-tert-Octylphenol 是一种干扰内分泌的化学物质及雌激素药物,能诱导子代小鼠脑神经元祖细胞的凋亡,并通过减少溴脱氧尿苷(BrdU)、有丝分裂标志物Ki67以及磷酸组蛋白H3(p-Histone-H3)的表达,导致神经元祖细胞的增殖减少。这种物质不仅会干扰小鼠的大脑发育,还会影响其行为。
T0086 Galanthamine hydrobromide

Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏

AChR; AChE Neuroscience
Galanthamine hydrobromide (Galantamine hydrobromide) 是一种长效的中枢活性 AChE 抑制剂,IC50为 410 nM。它是神经元烟碱型 ACh 受体的变构增强剂,IC50值为 0.35 µM,可用于阿尔茨海默症的研究。
T3861 Isobavachalcone

Corylifolinin,Isobacachalcone,补骨脂乙素

Apoptosis; Others; Reactive Oxygen Species; Akt; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Others; PI3K/Akt/mTOR signaling
Isobavachalcone (Corylifolinin) 是来源于补骨脂的一种Akt 信号通路抑制剂,可诱导人类癌细胞凋亡,以IC50值为 7.92 μM 抑制 OVCAR-8 癌细胞生长,具有抗癌和抗增殖活性。它还能诱导 OVCAR-8 细胞中活性氧的产生。
T14011 2-Arachidonoylglycerol

Cannabinoid Receptor; Endogenous Metabolite GPCR/G Protein; Metabolism
2-Arachidonoylglycerol 属于人内源性代谢物,是中枢神经系统中的一种内源性大麻素配体。
T2S2172 nerolidol

(±)-Nerolidol,Peruviol,橙花叔醇

Others; Endogenous Metabolite; Antibacterial; Parasite; Antifungal Metabolism; Microbiology/Virology; Others
Nerolidol (Peruviol) 是天然膜活性倍半萜,有抗肿瘤、抗细菌、抗真菌和抗寄生虫活性。它对动物有镇静作用,氧化过程对神经元病理后果起关键作用。
T3902 Atractylenolide III

白术内酯 III,ICodonolactone,8β-Hydroxyasterolide

Apoptosis Apoptosis
Atractylenolide III (ICodonolactone) 是白术根茎主要成分,通过诱导细胞色素 c 的释放、上调 Bax 的表达和易位凋亡诱导因子,是治疗人肺癌的潜力。
TN1957 Mulberrofuran Q

MulberrofuranQ

Mulberrofuran Q是一种有活性的化合物,可抑制12-羟基-5,8,10-十七碳三烯酸(HHT)和血栓烷B2(环加氧酶产物)的形成 ,可保护神经细胞免受缺氧-缺糖(OGD)诱导的氧化应激的影响。
T3S0645 N-trans-Feruloyltyramine

Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺

Others; COX Immunology/Inflammation; Neuroscience; Others
N-trans-Feruloyltyramine (Feruloyltyramine) 是从大麻中分离得到的一种生物碱,是COX1和COX2的抑制剂,具有抗氧化和抗炎活性。
T2O2741 Thiamine monochloride

Thiamine chloride,Vitamin B1

Others; Antioxidant; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; Others; oxidation-reduction
Thiamine monochloride (Vitamin B1) 是人体必不可少的维生素,具有促红细胞生成、调节血糖、抗氧化和调节情绪的作用。Thiamine monochloride 抑制铅引起的脂质过氧化反应,从而防止铅中毒。Thiamine monochloride 在摄入食物的细胞产生能量中起重要作用,并能增强正常的神经元活性。
T3S1068 Oxyresveratrol

trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene

Tyrosinase; Autophagy; HSV Autophagy; Microbiology/Virology; Proteases/Proteasome
Oxyresveratrol (trans-Oxyresveratrol) 是非竞争性酪氨酸酶抑制剂,对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1,HSV-2和水痘带状疱疹病毒,具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
T26288 Clovamide

trans-Clovamide,N-trans-Caffeoy-L-dopa

Apoptosis; Influenza Virus; ROS; Antibacterial Apoptosis; Immunology/Inflammation; Microbiology/Virology
Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物,具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
T6S1740 Nardosinone

苷松新酮,甘松新酮

Others Others
Nardosinone 是一个 dbcAMP 和 staurosporine 的神经生成作用增强剂,分离自Nardostachys chinensis 中。Nardosinone 可能成为一种有用的药理学工具,不仅可用于研究神经生长因子 (NGF) 的作用机理,而且可用于研究神经毒性物质的作用机理。
TN4368 Kaempferol-3,7-di-O-β-glucoside

Kaempferol 3,7-di-O-glucoside

Glucosidase; Amylase Metabolism
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) 是一种来自 Morettia philaena 的黄酮醇,对 α-淀粉酶 (α-amylase)、α-葡萄糖苷酶 (α-glucosidase) 和乙酰胆碱酯酶 (Acetylcholinesterase) 具有抑制作用。Kaempferol-3,7-di-O-β-glucoside 具有神经保护活性,可减缓分化神经元细胞 SH-SY5Y 免受 Amyloid β 肽诱导的损伤。Kaempferol-3,7-di-O-β-glucoside 可用于研究阿尔茨海默氏症类的神经系统疾病。
T4956 Tetrahydroxystilbene-2-O-β-D-glucoside

tetrahydroxyl diphenylethylene-2-o-gluco,何首乌苷,EH-201

Others Others
Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) 是一种低分子量的促红细胞生成素诱导剂。
T3826 Polygalasaponin F

异牡荆苷,瓜子金皂苷己

NF-κB; TLR; Akt; PI3K Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR signaling
Polygalasaponin F 是从瓜子金中提取的齐墩果烷型三萜皂苷,可通过调节TLR4-PI3K/AKT-NF-kB 信号通路减少神经炎症细胞因子的分泌,能降低炎性细胞因子肿瘤坏死因子 α 的释放。
TN1831 Macranthoside A

Kalopanaxsaponin H

Antioxidant oxidation-reduction
Macranthoside A (Kalopanaxsaponin H) 是一种从地黄中提取的三萜糖苷,属于环烯醚萜类化合。Macranthoside A 具有抗炎、抗氧化、抗菌和神经保护活性,抑制促炎细胞因子的产生和抑制炎症信号通路的激活,有助于中和有害的自由基,保护细胞免受氧化损伤,可以促进神经元的存活和生长,并防止氧化应激或神经毒性化合物引起的神经元细胞死亡,具有治疗神经退行性疾病、心血管疾病和肝损伤的潜力。
T4S0145 Corylifol A

Corylinin,补骨脂异黄酮A

hCE; STAT; UGT JAK/STAT signaling; Metabolism; Stem Cells
Corylifol A (Corylinin) 是补骨脂中的一种天然产物,可抑制IL-6 诱导的STAT3激活和磷酸化,IC50值为0.81 μM。
T37280 PE(18:1(9Z)/0:0)

Endogenous Metabolite Metabolism
PE(18:1(9Z)/0:0) 是一种天然存在的溶血磷脂,是缩醛磷脂溶血磷脂酰乙醇胺的类似物。 PE(18:1(9Z)/0:0) 以浓度依赖性方式诱导 PC12 大鼠神经元细胞中细胞内钙的瞬时增加。 PE(18:1(9Z)/0:0) 增加 IL-4 和 IL-2 的产生,但不增加 IFN-γ 的产生。 在小鼠血清中,PE(18:1(9Z)/0:0)(1 μg/动物)诱导 T 辅助细胞 2 反应。 在寒冷暴露三天后,小鼠肩胛间棕色脂肪组织中的 PE(18:1(9Z)/0:0) 水平增加。
T20493 Palmitone

NSC-953,NSC953,NSC 953

In the CA3 hippocampal region, Palmitone against pentylenetetrazole-caused neuronal damage.
T9454 4-Hydroxyestrone

Estrogen Receptor/ERR; Endogenous Metabolite Endocrinology/Hormones; Metabolism
4-Hydroxyestrone 是一种内源性雌激素代谢物,可强烈保护神经元细胞免受氧化损伤。
TN1581 Dihydroguaiaretic acid

二氢愈创木酸

COX; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Neuroscience
Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress.
TN4435 Licopyranocoumarin

P450; ROS; JNK Immunology/Inflammation; MAPK; Metabolism
Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane potential, which were mediated by JNK.
T4954L Smilagenin

PYM50028,Cogane,AI3-44895,PYM 50028

Smilagenin is an orally active inducer of nonpeptide neurotrophic factor. It also prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons, and by MPTP in a mouse model of Parkinson's disease.
T11041 Dihydro-β-erythroidine hydrobromide

DHβE hydrobromide

Others Others
Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs). Dihydro-β-carotene hydrobromide showed selectivity to α4β4 and α4β2nAChR, with IC50 of 0.19 and 0.37 μM,
T81814 Methyl Ganoderic acid B

Methyl Ganoderic acid B, 一种从灵芝中分离得到的三萜类化合物,具有类似神经生长因子的神经元存活促进作用。
T5143 Corynoxine hydrochloride(6877-32-3(free base))

Autophagy Autophagy
Corynoxine hydrochloride(6877-32-3(free base)) 是一种天然羟吲哚生物碱,可在不同的神经元细胞系(包括 N2a 和 SHSY-5Y 细胞)中诱导自噬。
TN2149 Reynosin

BCL; Others; TNF Apoptosis; Others
Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reciprocal up-regulation of E6-associated protein and down-regulation of α±-synuclein protein expr
T82058 Inubritannolide A

Inubritannolide A展示了对由多种诱导剂引起的神经细胞损伤具有微弱的保护作用,这些诱导剂包括H2O2、6-羟基多巴胺(6-OHDA)和脂多糖(LPS)。
TN1653 Fustin

ERK; Beta Amyloid; AChR MAPK; Neuroscience
Fustin 是植物漆树 (Rhus verniciflua Stokes) 的植物性黄烷醇成分。 Fustin 对 6-羟基多巴胺诱导的神经元细胞死亡具有保护作用。
T75469 Neoechinulin C

Neoechinulin C, 作为一种与棘菊糖有关的吲哌哌嗪生物碱,在帕金森病模型中通过防止百草枯引起的损害,有效地保护神经细胞。
TN3351 Aflatrem

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. Aflatrem potentiates the gamma-aminobutyric acid (GABA)-induced
T79998 Celosin K

Apoptosis Apoptosis
Celosin K,一种可从Semen Celosiae的种子中分离得到的化合物,有效抑制t-BHP引起的神经元损伤。该化合物通过抑制氧化应激、细胞凋亡和自噬过程发挥作用。
TN3410 Anatabine

Beta Amyloid; IL Receptor; TNF; NF-κB; BACE; COX; STAT Apoptosis; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; NF-κB; Stem Cells
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and reduces BACE-1 protein levels in hum
T82339 Gangliotetraose

Gg4

Gangliotetraose(Gg4)是一种含有GM1及其唾液酸化衍生物的四糖。它能促进分化神经元核内Ca2+的外流,进而降低核内Ca2+浓度。Gg4参与调节神经元的可塑性、修复过程以及大脑中神经营养素的释放。
T4S0823 Astragaloside

Others Others
Astragaloside 能够保护大鼠海马形态结构,恢复乙酰胆碱水平,并能够使脑电图正常化改善脑功能。
TN3741 Cyclocurcumin

TNF; ROS Apoptosis; Immunology/Inflammation
Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. It may have a therapeutic potential as
TN3806 Dehydroglyasperin C

ERK; IκB/IKK; p38 MAPK; TNF; NF-κB; Akt; COX; PI3K; NADPH; DNA/RNA Synthesis; Nrf2; JNK; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases
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天然产物

Spinosad
Cat.No: T9076
Synonym:
Target: Others
Adenosine
Cat.No: T0853
Synonym: 腺苷,D-Adenosine,Adenine riboside
Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy
Geranylgeraniol
Cat.No: TN6714
Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095
Target: Apoptosis
Anhydrosafflor yellow B
Cat.No: TN6924
Synonym: (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,脱水红花黄色素B,AHSYB
Target: Others
Galgravin
Cat.No: TN1038
Synonym:
Target: Apoptosis
Picroside III
Cat.No: T5S0733
Synonym:
Target: Others
Thiamine nitrate
Cat.No: T13923
Synonym: 硝酸硫胺,Vitamin B1 nitrate
Target: Others
Isocorynoxeine
Cat.No: T6S0654
Synonym: 7-Isocorynoxeine,异去氢钩藤碱
Target: 5-HT Receptor
Isobavachin
Cat.No: T3931
Synonym:
Target: Others
N-Acetyl-L-aspartic acid
Cat.No: T5287
Synonym: AC-ASP-OH,N-Acetylaspartic acid,N-乙酰-L-天门冬氨酸
Target: Others, Endogenous Metabolite
Rhynchophylline
Cat.No: T6S0659
Synonym: 钩藤碱,Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin
Target: Calcium Channel, NF-κB
Lobeline hydrochloride
Cat.No: T0268
Synonym: 盐酸洛贝林,α-Lobeline hydrochloride,L-Lobeline hydrochloride
Target: AChR
tubuloside B
Cat.No: T8852
Synonym:
Target: Apoptosis, Others
4-tert-Octylphenol
Cat.No: T64353
Synonym:
Target: Endogenous Metabolite
Galanthamine hydrobromide
Cat.No: T0086
Synonym: Galantamine hydrobromide,Galanthamine HBr,氢溴酸加兰他敏
Target: AChR, AChE
Isobavachalcone
Cat.No: T3861
Synonym: Corylifolinin,Isobacachalcone,补骨脂乙素
Target: Apoptosis, Others, Reactive Oxygen Species, Akt, Autophagy
2-Arachidonoylglycerol
Cat.No: T14011
Synonym:
Target: Cannabinoid Receptor, Endogenous Metabolite
nerolidol
Cat.No: T2S2172
Synonym: (±)-Nerolidol,Peruviol,橙花叔醇
Target: Others, Endogenous Metabolite, Antibacterial, Parasite, Antifungal
Atractylenolide III
Cat.No: T3902
Synonym: 白术内酯 III,ICodonolactone,8β-Hydroxyasterolide
Target: Apoptosis
Mulberrofuran Q
Cat.No: TN1957
Synonym: MulberrofuranQ
Target:
N-trans-Feruloyltyramine
Cat.No: T3S0645
Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺
Target: Others, COX
Thiamine monochloride
Cat.No: T2O2741
Synonym: Thiamine chloride,Vitamin B1
Target: Others, Antioxidant, Endogenous Metabolite, Antibacterial
Oxyresveratrol
Cat.No: T3S1068
Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene
Target: Tyrosinase, Autophagy, HSV
Clovamide
Cat.No: T26288
Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa
Target: Apoptosis, Influenza Virus, ROS, Antibacterial
Nardosinone
Cat.No: T6S1740
Synonym: 苷松新酮,甘松新酮
Target: Others
Kaempferol-3,7-di-O-β-glucoside
Cat.No: TN4368
Synonym: Kaempferol 3,7-di-O-glucoside
Target: Glucosidase, Amylase
Tetrahydroxystilbene-2-O-β-D-glucoside
Cat.No: T4956
Synonym: tetrahydroxyl diphenylethylene-2-o-gluco,何首乌苷,EH-201
Target: Others
Polygalasaponin F
Cat.No: T3826
Synonym: 异牡荆苷,瓜子金皂苷己
Target: NF-κB, TLR, Akt, PI3K
Macranthoside A
Cat.No: TN1831
Synonym: Kalopanaxsaponin H
Target: Antioxidant
Corylifol A
Cat.No: T4S0145
Synonym: Corylinin,补骨脂异黄酮A
Target: hCE, STAT, UGT
PE(18:1(9Z)/0:0)
Cat.No: T37280
Synonym:
Target: Endogenous Metabolite
Palmitone
Cat.No: T20493
Synonym: NSC-953,NSC953,NSC 953
Target:
4-Hydroxyestrone
Cat.No: T9454
Synonym:
Target: Estrogen Receptor/ERR, Endogenous Metabolite
Dihydroguaiaretic acid
Cat.No: TN1581
Synonym: 二氢愈创木酸
Target: COX, DNA/RNA Synthesis
Licopyranocoumarin
Cat.No: TN4435
Synonym:
Target: P450, ROS, JNK
Smilagenin
Cat.No: T4954L
Synonym: PYM50028,Cogane,AI3-44895,PYM 50028
Target:
Dihydro-β-erythroidine hydrobromide
Cat.No: T11041
Synonym: DHβE hydrobromide
Target: Others
Methyl Ganoderic acid B
Cat.No: T81814
Synonym:
Target:
Corynoxine hydrochloride(6877-32-3(free base))
Cat.No: T5143
Synonym:
Target: Autophagy
Reynosin
Cat.No: TN2149
Synonym:
Target: BCL, Others, TNF
Inubritannolide A
Cat.No: T82058
Synonym:
Target:
Fustin
Cat.No: TN1653
Synonym:
Target: ERK, Beta Amyloid, AChR
Neoechinulin C
Cat.No: T75469
Synonym:
Target:
Aflatrem
Cat.No: TN3351
Synonym:
Target: GABA Receptor
Celosin K
Cat.No: T79998
Synonym:
Target: Apoptosis
Anatabine
Cat.No: TN3410
Synonym:
Target: Beta Amyloid, IL Receptor, TNF, NF-κB, BACE, COX, STAT
Gangliotetraose
Cat.No: T82339
Synonym: Gg4
Target:
Astragaloside
Cat.No: T4S0823
Synonym:
Target: Others
Cyclocurcumin
Cat.No: TN3741
Synonym:
Target: TNF, ROS
Dehydroglyasperin C
Cat.No: TN3806
Synonym:
Target: ERK, IκB/IKK, p38 MAPK, TNF, NF-κB, Akt, COX, PI3K, NADPH, DNA/RNA Synthesis, Nrf2, JNK, Autophagy
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Cat. No. Product Name Species Expression System
TMPY-02646 NSE/ENO2 Protein, Human, Recombinant (His)

enolase 2 (γ, neuronal),NSE,HEL-S-279,enolase 2 (ga...

Human E. coli
The combination of silencing ENO2 and 2-deoxyglucose (2-DG) synergistically inhibited leukemia cell survival. ENO2 may be a biological marker for monitoring chemotherapeutic efficacy and relapse in ALL. Reduced ENO2 expression may be a biomarker for a subset of autistic children. Neuron specific enolase (ENO2, gamma-enolase) has been used as a biomarker to help identify neuroendocrine differentiation in breast cancer.
TMPY-01143 N Cadherin Protein, Human, Recombinant (His)

CDHN,CDw325,NCAD,CD325,cadherin 2, type 1, N-cadherin (n...

Human HEK293 Cells
N Cadherin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.5 kDa and the accession number is A0A024RC42.
TMPY-04856 LRRTM2 Protein, Human, Recombinant (hFc)

leucine rich repeat transmembrane neuronal 2

Human HEK293 Cells
LRRTM2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is O43300.
TMPY-01800 NEGR1 Protein, Mouse, Recombinant (His)

5330422G01Rik,KILON,neuronal growth regulator 1,Ntr...

Mouse HEK293 Cells
NEGR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is Q80Z24.
TMPY-05000 NPTXR Protein, Human, Recombinant (His)

neuronal pentraxin receptor,NPR

Human HEK293 Cells
NPTXR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.8 kDa and the accession number is O95502.
TMPY-00554 CHRNB3 Protein, Human, Recombinant (His)

cholinergic receptor, nicotinic, beta 3 (neuronal),...

Human HEK293 Cells
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Prot...
TMPY-01655 LRRTM4 Protein, Human, Recombinant (His)

leucine rich repeat transmembrane neuronal 4

Human HEK293 Cells
LRRTM4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q86VH4-1.
TMPJ-01130 NPTX1 Protein, Human, Recombinant (His)

Neuronal pentraxin-1,NPTX1,NP1

Human HEK293 Cells
Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co‑expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) at excitatory synapses. Mature human NPTX1 shares 97% aa sequence identity with mouse, and rat NPTX1. It is produced by hippocampal, cerebral and cerebellar neurons, retinal ganglia and the inner nuclear layer of the retina. It is enriched on presynaptic axonal membranes where it ...
TMPY-00068 LRRTM4 Protein, Mouse, Recombinant (His)

leucine rich repeat transmembrane neuronal 4,A23005...

Mouse HEK293 Cells
LRRTM4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.4 kDa and the accession number is Q80XG9-2.
TMPY-04195 CHRNB3 Protein, Human, Recombinant (hFc)

cholinergic receptor, nicotinic, β 3 (neuronal),cho...

Human HEK293 Cells
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Prot...
TMPY-04823 LRRTM2 Protein, Human, Recombinant (His)

leucine rich repeat transmembrane neuronal 2

Human HEK293 Cells
LRRTM2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is O43300.
TMPY-04321 CHRNA5 Protein, Human, Recombinant (His)

cholinergic receptor, nicotinic, α5 (neuronal),chol...

Human HEK293 Cells
Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer. CHRNA5 may influence susceptibility to lung cancer among Han smokers. Genetic variation in nicotinic receptor alpha 5 (CHRNA5) has been associated with increa...
TMPK-01030 LRRN1 Protein, Mouse, Recombinant (His)

Neuronal leucine-rich repeat protein 1,LRN,NLRR1,NL...

Mouse HEK293 Cells
Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation.
TMPY-03692 N Cadherin Protein, Human, Recombinant (His & hFc)

cadherin 2, type 1, N-cadherin (neuronal),CDw325,CD...

Human HEK293 Cells
N Cadherin Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is A0A024RC42.
TMPH-01763 CHRNB2 Protein, Human, Recombinant (His & V5)

CHRNB2,Neuronal acetylcholine receptor subunit beta...

Human E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions. CHRNB2 Protein, Human, Recombinant (His & V5) is expressed in E. coli expression system with N-10xHis-V5 tag. The predicted molecular weight is 31.9 kDa and the accession number is P17787.
TMPY-01913 NEGR1 Protein, Human, Recombinant (His)

KILON,IGLON4,DMML2433,Ntra,neuronal growth regulato...

Human HEK293 Cells
NEGR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.9 kDa and the accession number is Q7Z3B1-1.
TMPY-02491 LRRN3 Protein, Human, Recombinant (His)

NLRR3,FIGLER5,leucine rich repeat neuronal 3,NLRR-3

Human Baculovirus Insect Cells
Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a member of the leucine-rich (LRR) family whose members have significant functions in neural development. Leucine-rich repeats are short sequence motifs present in some proteins with diverse functions and cellular locations. All proteins containing these repeats are thought to be involved in protein-protein interactions. The crystal structure of ribonuclease inhibitor protein has revealed th...
TMPJ-00587 NRCAM Protein, Human, Recombinant (hFc)

gCAM-related cell adhesion molecule,hBravo,Ng-CAM-related,Nr...

Human HEK293 Cells
Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptog...
TMPY-03703 N Cadherin Protein, Mouse, Recombinant

Ncad,N-cadherin,CDHN,cadherin 2, type 1, N-cadherin (neu...

Mouse HEK293 Cells
N Cadherin Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 29 kDa and the accession number is P15116.
TMPH-02641 ECEL1 Protein, Mouse, Recombinant (His & Myc)

Ecel1,Endothelin-converting enzyme-like 1,Dine,Xce,Damage-in...

Mouse E. coli
May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
TMPH-01762 CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO)

CHRNA3,NACHRA3,Neuronal acetylcholine receptor subu...

Human E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 44.6 kDa and the accession number is P32297.
TMPH-01079 CLN5 Protein, Human, Recombinant (His)

CLN5,BMPS,Bis(monoacylglycero)phosphate synthase CLN5,S-depa...

Human E. coli
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane. CLN5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 43.5 kDa and ...
TMPH-00928 APBA2 Protein, Human, Recombinant (E. coli, His & Myc)

Neuronal Munc18-1-interacting protein 2 (Mint-2),Am...

Human E. coli
APBA2 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli.
TMPH-00929 APBA2 Protein, Human, Recombinant (His & Myc)

Adapter protein X11beta,MINT2,Neuronal Munc18-1-int...

Human HEK293 Cells
Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. APBA2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 87.5 kDa and the accession number is Q99767.
TMPJ-00722 APBA3 Protein, Human, Recombinant (His)

Neuronal Munc18-1-Interacting Protein 3,Neuron-Spec...

Human E. coli
Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amylo...
TMPJ-01052 DYNLL1 Protein, Human, Recombinant (His)

DNCL1,PIN,DLC8,Protein Inhibitor of Neuronal Nitric...

Human E. coli
Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain.
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant

NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3

Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ...
TMPY-05510 BDNF Protein, Mouse, Recombinant (His)

brain-derived neurotrophic factor

Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPH-01031 CAPN2 Protein, Human, Recombinant (His)

Calpain-2 catalytic subunit,Millimolar-calpain,Calpain-2 lar...

Human E. coli
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. CAPN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82...
TMPJ-01468 pro-Beta NGF Protein, Human, Recombinant

β-NGF,NGF,NGFB,Beta-NGF,Beta-Nerve Growth Factor,pro-Beta NG...

Human E. coli
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
TMPJ-00090 FGF-9 Protein, Human, Recombinant

Fibroblast Growth Factor 9,Heparin-Binding Growth Factor 9,F...

Human E. coli
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In addition, FGF-9 may have a role in glial c...
TMPY-05054 Notch 4 Protein, Human, Recombinant (His)

INT3,notch 4

Human Baculovirus Insect Cells
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is involved in the development and patterning of the central nervous systems. It regulates signaling pathways associated with neuronal maturation, a process involved in the development and patterning of the central nervous system. The NOTCH4 gene has also been identified as a possibl...
TMPY-03425 Tau Protein, Human, Recombinant (His)

PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ...

Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPJ-00037 FGF-2 Protein, Mouse, Recombinant

Fibroblast Growth Factor 2,bFGF,HBGF-2,Basic Fibroblast Grow...

Mouse E. coli
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mouse sequence has 98% aa identity with rat, and 95% identity with human, bovine, and sheep FGF basic. Binding of FGF to heparin or cell surface HSPG is necessary for binding, dimerization and activation of tyrosine kinase FGF receptors. FGF basic binds other proteins, polysacchari...
TMPY-01355 Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)

G-α-h,HEL-S-45,TGC,transglutaminase 2,TG2,GNAH,G-ALPHA-h

Human Baculovirus Insect Cells
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which...
TMPJ-01011 FGF-9 Protein, Mouse, Recombinant (His)

heparin-binding growth factor-9,GAF,HBGF-9,Glia-activating f...

Mouse E. coli
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, v...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ106...

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPH-02805 NEFL Protein, Mouse, Recombinant (His)

Mouse P. pastoris (Yeast)
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFL Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63.4 kDa and the accession number is P08551.
TMPH-01758 NEFL Protein, Human, Recombinant

Human E. coli
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFL Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 61.5 kDa and the accession number is P07196.
TMPH-01759 NEFL Protein, Human, Recombinant (His & SUMO)

Human E. coli
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFL Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with C-6xHis-SUMO tag. The predicted molecular weight is 52.4 kDa and the accession number is P07196.
TMPH-01757 NEFH Protein, Human, Recombinant (His & Myc & SUMO)

Human E. coli
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFH Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc...
TMPH-01760 NEFM Protein, Human, Recombinant (His & Myc)

Human E. coli
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFM Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.8 kDa and the accession number is P07197.
TMPH-03754 NAV1 Protein, Human, Recombinant (His)

Human E. coli
May be involved in neuronal migration.
TMPH-03340 NEFH Protein, Rat, Recombinant (His & Myc)

Rat E. coli
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NEF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. NEFH Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The pre...
TMPH-01227 DPYSL2 Protein, Human, Recombinant (His)

Dihydropyrimidinase-related protein 2,Collapsin response med...

Human P. pastoris (Yeast)
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
TMPH-01229 DPYSL5 Protein, Human, Recombinant (His & Myc)

ULIP6,CRMP-5,CRMP5,DRP-5,DPYSL5,Dihydropyrimidinase-related ...

Human E. coli
May have a function in neuronal differentiation and/or axon growth.
TMPY-02718 Doublecortin/DCX Protein, Human, Recombinant (aa 45-150, GST)

XLIS,doublecortin,LISX,DBCN,DC,SCLH

Human E. coli
DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it is highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. DCX is a microtubule-associated protein required for initial steps of neuronal dispersion an...
TMPY-05088 CNTN6 Protein, Human, Recombinant (hFc)

NB3,contactin 6

Human HEK293 Cells
Copy number variations (CNVs) of the human CNTN6 gene caused by megabase-scale microdeletions or microduplications in the 3p26.3 region are often the cause of neurodevelopmental disorders, including intellectual disability and developmental delay. Contactin genes CNTN5 and CNTN6 code for neuronal cell adhesion molecules that promote neurite outgrowth in sensory-motor neuronal pathways. The deletion or duplication of the CNTN6 gene is associated with a wide spectrum of neurodevelopmental behavior...
TMPH-02754 LGI3 Protein, Mouse, Recombinant (His)

Mouse E. coli
May participate in the regulation of neuronal exocytosis. LGI3 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 62.7 kDa and the accession number is Q8K406.
TMPH-03391 TRIM2 Protein, Rat, Recombinant (His)

Rat E. coli
E3 ubiquitin-protein ligase that mediates the ubiquitination of phosphorylated BCL2L11. Also mediates the UBE2D1-dependent ubiquitination of NEFL. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. TRIM2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.5 kDa and the accession number is D3ZQG6.
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重组蛋白

NSE/ENO2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02646
Species: Human
Expression System: E. coli
N Cadherin Protein, Human, Recombinant (His)
Cat.No: TMPY-01143
Species: Human
Expression System: HEK293 Cells
LRRTM2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04856
Species: Human
Expression System: HEK293 Cells
NEGR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01800
Species: Mouse
Expression System: HEK293 Cells
NPTXR Protein, Human, Recombinant (His)
Cat.No: TMPY-05000
Species: Human
Expression System: HEK293 Cells
CHRNB3 Protein, Human, Recombinant (His)
Cat.No: TMPY-00554
Species: Human
Expression System: HEK293 Cells
LRRTM4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01655
Species: Human
Expression System: HEK293 Cells
NPTX1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01130
Species: Human
Expression System: HEK293 Cells
LRRTM4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00068
Species: Mouse
Expression System: HEK293 Cells
CHRNB3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04195
Species: Human
Expression System: HEK293 Cells
LRRTM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04823
Species: Human
Expression System: HEK293 Cells
CHRNA5 Protein, Human, Recombinant (His)
Cat.No: TMPY-04321
Species: Human
Expression System: HEK293 Cells
LRRN1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01030
Species: Mouse
Expression System: HEK293 Cells
N Cadherin Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-03692
Species: Human
Expression System: HEK293 Cells
CHRNB2 Protein, Human, Recombinant (His & V5)
Cat.No: TMPH-01763
Species: Human
Expression System: E. coli
NEGR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01913
Species: Human
Expression System: HEK293 Cells
LRRN3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02491
Species: Human
Expression System: Baculovirus Insect Cells
NRCAM Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00587
Species: Human
Expression System: HEK293 Cells
N Cadherin Protein, Mouse, Recombinant
Cat.No: TMPY-03703
Species: Mouse
Expression System: HEK293 Cells
ECEL1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02641
Species: Mouse
Expression System: E. coli
CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01762
Species: Human
Expression System: E. coli
CLN5 Protein, Human, Recombinant (His)
Cat.No: TMPH-01079
Species: Human
Expression System: E. coli
APBA2 Protein, Human, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-00928
Species: Human
Expression System: E. coli
APBA2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00929
Species: Human
Expression System: HEK293 Cells
APBA3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00722
Species: Human
Expression System: E. coli
DYNLL1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01052
Species: Human
Expression System: E. coli
Neurotrophin 3 Protein, Human, Recombinant
Cat.No: TMPY-04069
Species: Human
Expression System: E. coli
BDNF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05510
Species: Mouse
Expression System: HEK293 Cells
CAPN2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01031
Species: Human
Expression System: E. coli
pro-Beta NGF Protein, Human, Recombinant
Cat.No: TMPJ-01468
Species: Human
Expression System: E. coli
FGF-9 Protein, Human, Recombinant
Cat.No: TMPJ-00090
Species: Human
Expression System: E. coli
Notch 4 Protein, Human, Recombinant (His)
Cat.No: TMPY-05054
Species: Human
Expression System: Baculovirus Insect Cells
Tau Protein, Human, Recombinant (His)
Cat.No: TMPY-03425
Species: Human
Expression System: E. coli
FGF-2 Protein, Mouse, Recombinant
Cat.No: TMPJ-00037
Species: Mouse
Expression System: E. coli
Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01355
Species: Human
Expression System: Baculovirus Insect Cells
FGF-9 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01011
Species: Mouse
Expression System: E. coli
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
NEFL Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02805
Species: Mouse
Expression System: P. pastoris (Yeast)
NEFL Protein, Human, Recombinant
Cat.No: TMPH-01758
Species: Human
Expression System: E. coli
NEFL Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01759
Species: Human
Expression System: E. coli
NEFH Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01757
Species: Human
Expression System: E. coli
NEFM Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01760
Species: Human
Expression System: E. coli
NAV1 Protein, Human, Recombinant (His)
Cat.No: TMPH-03754
Species: Human
Expression System: E. coli
NEFH Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03340
Species: Rat
Expression System: E. coli
DPYSL2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01227
Species: Human
Expression System: P. pastoris (Yeast)
DPYSL5 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01229
Species: Human
Expression System: E. coli
Doublecortin/DCX Protein, Human, Recombinant (aa 45-150, GST)
Cat.No: TMPY-02718
Species: Human
Expression System: E. coli
CNTN6 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05088
Species: Human
Expression System: HEK293 Cells
LGI3 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02754
Species: Mouse
Expression System: E. coli
TRIM2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03391
Species: Rat
Expression System: E. coli
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