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TMPY-01769
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4EBP1 Protein, Human, Recombinant (His)
4E-BP1,eukaryotic translation initiation f...
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Human
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E. coli
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The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcription factor activating transcription factor-4 (ATF4), a master regulator of gene expression in stress responses. 4E-BP1 is characterized by its capacity to bind specifically to eIF4E and inhibit its interaction with eIF4G. Phosphorylation of 4E-BP1 regulates eIF4E availability, a... |
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TMPY-02444
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ATF2 Protein, Human, Recombinant (His & GST)
CREB2,CRE-BP1,CREB-2,TREB7,activating tran...
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Human
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Baculovirus Insect Cells
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Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has ... |
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TMPK-00729
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Siglec-6 Protein, Human, Recombinant (His & Avi)
SIGLEC6,OBBP1,CD327,CD33L1,CD33 a...
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Human
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HEK293 Cells
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Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains.Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
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TMPY-00146
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RKIP/PEBP1 Protein, Human, Recombinant
PBP,HEL-S-34,PEBP,RKIP,HCNP,PEBP-...
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Human
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E. coli
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Phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein, belongs to PEBP family of proteins. It is known to interact with many proteins that are mainly involved in pathways that monitor cell proliferation and differentiation. PEBP1 in many cells interacts with several pathways, namely MAPK, GRK2, NF-small ka, CyrillicB, etc. that keeps the cell proliferation and differentiation in check. This protein is expressed by many cells in humans, including neurons w... |
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TMPH-01786
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NCBP1 Protein, Human, Recombinant (His & Myc)
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Human
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Baculovirus Insect Cells
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NCBP1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 95.7 kDa and the accession number is Q09161. |
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TMPY-03456
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SRFBP1 Protein, Human, Recombinant (His & GST)
STRAP,BUD22,P49,serum response factor binding protein 1<...
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Human
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Baculovirus Insect Cells
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SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. SRFBP1 negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein. SRF... |
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TMPH-03737
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ABP1 Protein, Zea mays, Recombinant (His)
Auxin-binding protein 1,ABP,ERABP...
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Zea mays
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E. coli
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Receptor for the plant hormone auxin. |
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TMPY-01595
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PCBP1 Protein, Human, Recombinant (His)
HNRPE1,hnRNP-E1,HEL-S-85,HNRPX,poly(rC) bi...
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Human
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E. coli
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Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in pr... |
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TMPY-03864
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CRABP1 Protein, Human, Recombinant
CRABP,CRABP-I,RBP5,cellular retin...
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Human
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E. coli
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CRABP1 is a specific binding protein for a vitamin A family member. It is thought that CRABP1 plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. It forms a beta-barrel structure which accommodates hydrophobic ligands in its interior. |
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TMPJ-00814
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RBP1 Protein, Human, Recombinant
Cellular retinol-binding protein I,CRBP-I,RBP
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Human
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E. coli
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RBP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14 KDa and the accession number is P09455. |
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TMPY-01820
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Munc18-1/STXBP1 Protein, Human, Recombinant (His & GST)
MUNC18-1,RBSEC1,P67,syntaxin bind...
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Human
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Baculovirus Insect Cells
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Syntaxin-binding protein 1, also known as N-Sec1, Protein unc-18 homolog 1, MUNC18-1 and STXBP1, is a peripheral membrane protein that belongs to the STXBP / unc-18 / SEC1 family. STXBP1 is an evolutionally conserved neuronal Sec1/Munc-18 (SM) protein that is essential in synaptic vesicle release in several species. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. STXBP1 is essential for neurotransmission and bin... |
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TMPH-01998
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G3BP1 Protein, Human, Recombinant (His)
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Human
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E. coli
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G3BP1 Protein, Human, Recombinant (His) is expressed in E. coli. |
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TMPH-02166
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STXBP1 Protein, Human, Recombinant
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Human
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E. coli
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Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. |
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TMPH-00106
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TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
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Arabidopsis thaliana
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E. coli
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General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.3 kDa and the accession number is P28147. |
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TMPY-00559
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GPIHBP1 Protein, Human, Recombinant (His)
GPI-HBP1,HYPL1D,glycosylphosphati...
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Human
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HEK293 Cells
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GPIHBP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is Q8IV16. |
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TMPJ-01328
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ZBP1 Protein, Human, Recombinant (His)
Tumor Stroma and Activated Macrophage Protein DLM,DLM1
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Human
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E. coli
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Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of viral and bacterial DNA from by the host's innate immune system. It plays a role in host defense against tumors and pathogens. ZBP1 Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream ... |
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TMPY-03385
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FKBP14 Protein, Human, Recombinant (His)
IPBP12,EDSKMH,FK506 binding protein 1<...
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Human
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HEK293 Cells
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FKBP14 belongs to the FK506-binding protein family. It contains 2 EF-hand domains and one PPIase FKBP-type domain. FKBP14 can be detected in the lumen of the endoplasmic reticulum where it is thought to accelerate the folding of proteins during protein synthesis. Truncation of the amino-terminus of FKBP14 significantly decreases peptidyl prolyl cis-trans isomerase activity, therefore implicating that the PPIase FKBP-type domain must be located at the N-terminus. Defects in FKBP14 can cause Ehler... |
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TMPH-01785
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NCBP1 Protein, Human, Recombinant (E. coli, His & Myc)
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Human
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E. coli
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NCBP1 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 99.3 kDa and the accession number is Q09161. |
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TMPH-02703
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HEBP1 Protein, Mouse, Recombinant (hFc)
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Mouse
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HEK293 Cells
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HEBP1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293. |
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TMPJ-01272
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WBP1 Protein, Human, Recombinant (His)
WBP1,WBP-1,WW Domain-Bin...
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Human
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E. coli
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WW Domain-Binding Protein 1 (WBP1) is widely expressed in many tissues, but it is lowly expressed in the lung, placenta, kidney, and liver. WBP1 contains two WW-binding motifs: WW-binding 1 and WW-binding 2 that are involved in mediating protein-protein interactions through the binding of polyproline ligands. The WW-binding domain is composed of 38 to 40 semi-conserved amino acids shared by proteins with diverse functions including structural, regulatory, and signaling proteins. In addition, WBP... |
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TMPH-00407
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PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO)
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Clostridium botulinum
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E. coli
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PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli. |
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TMPH-01888
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PTBP1 Protein, Human, Recombinant (His)
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Human
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HEK293 Cells
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PTBP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 63.1 kDa and the accession number is P26599?. |
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TMPH-03044
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PBP1a Protein, MenB, Recombinant (His & SUMO)
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MenB
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E. coli
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Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). |
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TMPH-02494
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AEBP1 Protein, Mouse, Recombinant (His & SUMO)
Adipocyte enhancer-binding protein 1,Aortic carboxy...
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Mouse
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E. coli
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AEBP1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.8 kDa and the accession number is Q640N1. |
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TMPH-03046
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TBP1 Protein, MenB, Recombinant (His & Myc)
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MenB
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E. coli
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Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Binds both apo- and holo-TF, via the TF C-terminus. |
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TMPH-02403
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JBP1 Protein, Leishmania infantum, Recombinant (His & V5)
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Leishmania infantum
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E. coli
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JBP1 Protein, Leishmania infantum, Recombinant (His & V5) is expressed in E. coli expression system with N-10xHis-V5 tag. The predicted molecular weight is 53.4 kDa and the accession number is A4HU70. |
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TMPY-01662
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FKBP12 Protein, Mouse, Recombinant (His)
FK506 binding protein 1A,Fkbp1,FK...
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Mouse
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E. coli
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FKBP12 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.7 kDa and the accession number is P26883. |
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TMPH-02702
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HEBP1 Protein, Mouse, Recombinant (His)
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Mouse
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E. coli
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HEBP1 Protein, Mouse, Recombinant (His) is expressed in E. coli. |
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TMPY-00510
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FKBP11 Protein, Human, Recombinant (mFc)
FKBP19,FK506 binding protein 1
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Human
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HEK293 Cells
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FKBP11 serve as biomarker and/or therapeutic target for Acute aortic dissection (AAD). FKBP11 during the development of HCC and FKBP11 has the potential to be an early marker for HCC. |
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TMPY-00557
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GPIHBP1 Protein, Human, Recombinant (hFc)
glycosylphosphatidylinositol anchored high density lipoprote...
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Human
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HEK293 Cells
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GPIHBP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is Q8IV16. |
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TMPY-00808
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FKBP12 Protein, Human, Recombinant (His)
FKBP12,FKBP1,FKBP
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Human
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E. coli
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FKBP12 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12.9 kDa and the accession number is P62942. |
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TMPH-02165
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STXBP1 Protein, Human, Recombinant (His)
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Human
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HEK293 Cells
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Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. |
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TMPY-03283
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HBP1 Protein, Human, Recombinant (GST)
HMG-box transcription factor 1
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Human
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E. coli
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HBP1 is a sequence-specific DNA-binding transcription factor. It is involved in many biological processes. It was reported that HBP1 binds to p16(INK4A) promoter and activates p16(INK4A) expression. We found that trichostatin A (TSA), an inhibitor of HDAC (histone deacetylase), induces p16(INK4A) expression in an HBP1-dependent manner. HBP1 activates or represses the expression of some specific genes during cell growth and differentiation. HBP1 was acetylated by p3/CBP in two regions: repression... |
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TMPY-02549
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GBP1 Protein, Human, Recombinant (His)
guanylate binding protein 1,GBP1
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Human
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HEK293 Cells
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Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 expression is induced by type1 and type2 interferons, including IFN-λ and also by interleukin-1β (IL-1β), IL-1α, and tumor necrosis factor-α (TNF-α). GBP-1 is key to the protective immunity against microbial and viral pathogens. GBP-1 was only secreted from endothelial cells. Secre... |
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TMPY-02844
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EBP1 Protein, Human, Recombinant (His)
proliferation-associated 2G4,EBP1,p38-2G4,...
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Human
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E. coli
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EBP1, also known as PA2G4, is an RNA-binding protein that belongs to the peptidase M24 family. It can be detected n several cell lines tested, including primary and transformed cell lines. EBP1 also present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein is a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its int... |
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TMPH-00701
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PBP1b Protein, E. coli, Recombinant (His & Myc)
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E. coli
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E. coli
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Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). PBP1b Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.6 kDa and the accession number is P02919... |
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TMPY-00140
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ABP1/AOC1 Protein, Human, Recombinant (His)
amine oxidase, copper containing 1,DAO,ABP...
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Human
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HEK293 Cells
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Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under co... |
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TMPJ-01386
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STUB1 Protein, Human, Recombinant
Carboxy Terminus of Hsp70-Interacting Protein,STIP1...
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Human
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E. coli
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E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its TPR domain; lead to in client substrate ubiquitylation and degradation by the proteasome. CHIP targets misfolded chaperone substrates towards proteasomal degradation. CHIP mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.... |
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