购物车
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TopBP1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13675

Anti-TopBP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TopBP1。Anti-TopBP1 Polyclonal Antibody 可用于 WB。

Anti-TopBP1 Polyclonal Antibody

Anti-TopBP1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13675

Anti-TopBP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TopBP1。Anti-TopBP1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-TopBP1 Polyclonal Antibody is a Rabbit antibody targeting TopBP1. Anti-TopBP1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm; cytoskeleton; centrosome. Cytoplasm; cytoskeleton; spindle pole. Chromosome. Detected on unpaired autosomes in meiotic prophase cells. Detected on X and Y chromosomes during later stages of prophase. Colocalizes with ATR and H2AFX at unsynapsed chromosome cores during prophase (By similarity). Has a uniform nuclear distribution during G phase. Colocalizes with BRCA1 at stalled replication forks during S phase. In mitotic cells it colocalizes with BRCA1 at spindle poles and centrosomes during metaphase and anaphase. Detected in discrete foci together with PML and numerous DNA repair enzymes after DNA damage by alkylating agents, UV or gamma irradiation.
组织特异性Highly expressed in heart, brain, placenta, lung and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TopBP1
抗原种属
Human
基因名称
TOPBP1
基因ID
11073
蛋白名称
DNA topoisomerase 2-binding protein 1
Uniprot ID
Q92547
化学信息
分子量Theoretical: 171 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
Related Tags: buy Anti-TopBP1 Polyclonal Antibody | purchase Anti-TopBP1 Polyclonal Antibody | Anti-TopBP1 Polyclonal Antibody cost | order Anti-TopBP1 Polyclonal Antibody | Anti-TopBP1 Polyclonal Antibody molecular weight