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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CDKN2B/p15 INK4b Polyclonal Antibody

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货号 TMAB-04185

Anti-CDKN2B/p15 INK4b Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CDKN2B/p15 INK4b。Anti-CDKN2B/p15 INK4b Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-CDKN2B/p15 INK4b Polyclonal Antibody

Anti-CDKN2B/p15 INK4b Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04185

Anti-CDKN2B/p15 INK4b Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CDKN2B/p15 INK4b。Anti-CDKN2B/p15 INK4b Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CDKN2B/p15 INK4b Polyclonal Antibody is a Rabbit antibody targeting CDKN2B/p15 INK4b. Anti-CDKN2B/p15 INK4b Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Note=Also found in the nucleus.
组织特异性Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景p15 INK4b / MTS 2 (Mitotic Inhibitor / Suppressor Protein) is a specific inhibitor of cdk 4 / cdk 6 and is periodically expressed during the cell cycle. Reportedly, p15 INK4b expression is induced approximately 30 fold in human keratinocytes by treatment with TGF beta, suggesting that p15 INK4b may act as an effector of TGF beta mediated cell cycle arrest. p15 INK4b is mapped to chromosome 9p21, a region of frequent loss in a wide variety of cancers.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CDKN2B
抗原种属
Human
基因名称
CDKN2B
基因ID
1030
蛋白名称
Cyclin-dependent kinase 4 inhibitor B
Uniprot ID
P42772
功能
Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
化学信息
分子量Theoretical: 15 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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