(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1].
3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1].
[1]. Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydroxyvitamin D3 over 1 α 25-dihydroxyvitamin D3: metabolism and molecular docking studies using rat CYP24A1. J Cell Biochem. 2013 Oct;114(10):2293-305.
DL-Glutamic acid, the conjugate acid of Glutamic acid, serves as a crucial metabolite. In comparison to the α and β polymorphs of L-Glutamic acid's second phase, DL-Glutamic acid exhibits enhanced stability[1].
DL-Glutamic acid (Standard) is the standard substance of DL-Glutamic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. DL-Glutamic acid, the conjugate acid of Glutamic acid, serves as a crucial metabolite. In comparison to the α and β polymorphs of L-Glutamic acid's second phase, DL-Glutamic acid exhibits enhanced stability.
Pochonin D 是一种抑制热休克蛋白 90 (Hsp90) 的化合物,展现出抗病毒和抗炎特性。通过抑制 Hsp90,Pochonin D 影响病毒蛋白的稳态、折叠及组装,降低病毒复制能力。此外,它减少炎症细胞的浸润和炎性细胞因子(如 TNF-α、IL-1β)的分泌,从而减轻炎症反应。Pochonin D 在人鼻病毒 (HRV) 感染和癌症研究中具有应用潜力。