327
60
5
1
131
Cat. No. | Product Name | ||
---|---|---|---|
L7810 | 高溶解性多官能团片段化合物库 | 1159 compounds | |
高溶解性多官能团片段库包含1159 种片段分子 | |||
L7850 | 高溶解性3D结构多样性片段化合物库 | 1079 compounds | |
高溶解性3D 结构多样性片段库包含1079 个化合物。 | |||
L7840 | 高溶解性卤化片段化合物库 | 796 compounds | |
高溶解性卤化片段库包含796 个卤化片段化合物。 | |||
L7820 | 高溶解性微型片段化合物库 | 1081 compounds | |
高溶解性微型片段化合物库由 1081 个低分子量片段组成。 | |||
L7870 | 可溶性羧酸片段化合物库 | 1806 compounds | |
可溶性羧酸片段库包含 1806 个化合物 |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0005 |
Cell Counting Kit-8 (CCK-8)
Cell Counting Kit-8 (CCK-8) |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T83857 |
Soluble Epoxide Hydrolase PROTAC 1a
sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a |
||
Soluble epoxide hydrolase (sEH) PROTAC 1a是一种利用蛋白质降解靶向嵌合体(PROTAC)技术,通过连接区域将cereblon配体1与sEH抑制剂t-TUCB结合。该化合物通过促进sEH的降解,特异性抑制sEH的水解酶活性(IC50 = 0.8 nM),相较于其磷酸酶活性(IC50 = >10,000 nM)具有较高选择性。sEH PROTAC 1a还特定促进细胞质中而非过氧体中的sEH降解,并通过溶酶体而非蛋白酶体实现其降解。它能够降低thapsigargin诱导的HepG2与293T细胞中磷酸化的inositol-requiring enzyme 1α (IRE1α)水平和X-box结合蛋白1 (XBP1)剪接,表明能减少ER应激。 | |||
T12974 |
Soluble epoxide hydrolase inhibitor
|
Others | Others |
Soluble epoxide hydrolase inhibitor is a soluble epoxide hydrolase inhibitor (human soluble epoxide hydrolase (h-sEH) with pIC50 of 8.4). | |||
T13029 |
Sulfamerazine sodium salt
Soluble sulfamerazine,磺胺甲基嘧啶钠 |
Others | Others |
Sulfamerazine sodium salt is a sulfonamide antibacterial. | |||
T7898 |
AUDA
|
Epoxide Hydrolase | Metabolism |
AUDA 是可溶性环氧化物水解酶 (sEH) 抑制剂,在小鼠和人 sEH 的IC50分别为 18 和 69 nM,具有抗炎特性。 | |||
T30661 |
C.I. 73336
Fenanthra Orange HR,Indigo Soluble Brilliant Orange K |
||
C.I. 73336 is an orange dye. | |||
T14557 |
BI-1935
|
Epoxide Hydrolase | Metabolism |
BI-1935 是可溶性环氧化物水解酶抑制剂,用于与心血管疾病相关的疾病的研究。 | |||
T21712 |
BAY 41-8543
|
Others; Guanylate cyclase | GPCR/G Protein; Others |
BAY 41-8543 是一种不依赖一氧化氮的可溶性鸟苷酸环化酶 (sGC) 刺激剂,具有抗血小板作用。它在大鼠的肺和全身血管床中具有血管舒张活性,有用于心血管疾病的研究潜力。 | |||
T21607 |
Ataciguat
HMR-1766 |
Others; Guanylate cyclase | GPCR/G Protein; Others |
Ataciguat (HMR-1766) 是一种不依赖一氧化氮的可溶性鸟苷酸环化酶 (sGC) 激活剂,具有血管舒张作用。它能够激活 sGC 的铁血红素铁氧化还原形式,刺激 cGMP 的产生。 | |||
T17158 |
trans-AUCB
t-AUCB |
Epoxide Hydrolase | Metabolism |
trans-AUCB (t-AUCB) 是口服具有活力的、选择性的可溶性环氧水解酶 (sEH) 抑制剂,对人,小鼠和大鼠的 sEH 的IC50分别为 1.3 nM,8 nM,8 nM。它具有抗神经胶质瘤特性。 | |||
T36587 |
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt
|
Others | Others |
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt 是一种阴离子荧光染料,用作葡萄糖传感和检测其他糖类的报告分子。激发/发射光谱为 425/503 nm。 它可以在溶液中使用,也可以通过还原胺化连接醛官能化单体来固定,而不会显著改变荧光强度。 | |||
T10900 |
CUDA
|
PPAR; Epoxide Hydrolase | DNA Damage/DNA Repair; Metabolism |
CUDA 是一种可溶性环氧水解酶抑制剂,对小鼠 sEH 和人 sEH 作用的 IC50分别为 11.1 和 112 nM。它能选择性地上调过氧化物酶体增殖激活受体 PPARα的活性,有用于心血管疾病的研究潜力。 | |||
T14315 |
AR-9281
APAU |
Epoxide Hydrolase | Metabolism |
AR-9281 (APAU) 是选择性的可溶性环氧化物水解酶抑制剂,可用于研究高血压和 2 型糖尿病。 | |||
T11147 |
EC5026
BPN-19186 |
Epoxide Hydrolase | Metabolism |
EC5026 (BPN-19186) 是首创的,非阿片类的,可溶性环氧水解酶 (sEH) 抑制剂,它可有效缓解发炎性和神经性疼痛。 | |||
T8682 |
Vazegepant hydrochloride
Vazegepant HCl |
CGRP Receptor | GPCR/G Protein; Neuroscience |
Vazegepant hydrochloride (Vazegepant HCl) 是一种用于偏头痛的鼻用 gepant,是一种高度亲和性CGRP 受体拮抗剂 (hCGRPKi=0.023 nM)。它可能有助于有效管理 COVID-19 相关肺部炎症。 | |||
T2178 |
AMI5
AMI 5,Eosin Y Disodium,AMI-5 |
Others | Others |
AMI5 (Eosin Y Disodium) 是一种具有可溶性的酸性红色染料分子。它常用于机合成中的光氧化还原催化剂。 | |||
T24493 |
Monoelaidin
|
||
Monoelaidin is a poorly water-soluble drug enhancer of solubility and oral bioavailability. | |||
T7201 |
Nelociguat
N-[4,6-二氨基-2-[1-[(2-氟苯基)甲基]-1H-吡唑并[3,4-B]吡啶-3-基]-5-嘧啶]-氨基甲酸甲酯,BAY60-4552 |
Guanylate cyclase | GPCR/G Protein |
Nelociguat (BAY60-4552) 是一种一氧化氮敏感的可溶性鸟苷酸环化酶刺激剂。 | |||
T19362 |
Hydroxyethyl cellulose
Cellulose hydroxyethyl ether,羟乙基纤维素,2-Hydroxyethyl cellulose |
Others | Others |
Hydroxyethyl cellulose (2-Hydroxyethyl cellulose) 是一种非离子水溶性改性纤维素聚合物,能够用作水溶性化妆品和个人护理配方中的增稠剂。 | |||
T15787 |
LRE1
|
Adenylyl cyclase | Neuroscience |
LRE1是可溶性腺苷酸环化酶的特异性和变构抑制剂。 | |||
T21576 |
LY83583
6-Anilino-5,8-quinolinedione,6-anilinoquinoline-5,8-dione |
Guanylate cyclase | GPCR/G Protein |
LY83583 是一种可溶性鸟苷酸环化酶竞争性抑制剂,IC50 为 2 µM。 | |||
T4449 |
LB100
LB-100,LB 100 |
Phosphatase | Metabolism |
LB100 (LB-100) 是一种水溶性蛋白磷酸酶 2A(PP2A) 抑制剂。 | |||
T23044 |
N,N'-Dicyclohexylurea
DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582,N,N-二环己脲 |
Epoxide Hydrolase | Metabolism |
N,N'-Dicyclohexylurea (AURORA KA-3582) 是一种可溶性环氧化物水解酶 (sEH) 抑制剂。 | |||
T6818 |
DEL-22379
DEL22379 |
Apoptosis; ERK | Apoptosis; MAPK |
DEL-22379 是一种水溶性 ERK 二聚化抑制剂,IC50约为 0.5 μM。 | |||
T5328 |
Fosfluconazole
|
Antifungal | Microbiology/Virology |
Fosfluconazole 是 fluconazole 的水溶性磷酸盐前药。 它是一种抗真菌药物。 | |||
T15025L |
CY5 triethylamine salt
CY5 triethylamine salt(146368-11-8 Free base) |
Others | Others |
CY5 triethylamine salt 是一种水溶性染料,激发光波长(nm):649,发射波长(nm):670。 | |||
T20067 |
WST-1
WST 1 |
||
WST-1 是一种具有细胞毒性的水溶性四唑盐,诱导细胞内线粒体脱氢酶进行 NADH 依赖性酶解反应,释放出水溶性甲基苯产物。WST-1 可通过检测吸收值来检测细胞增殖和细胞活性,可用于WST-1平板测定法测定超氧化物歧化酶活性。 | |||
T10378 |
Artelinic acid
|
Parasite | Microbiology/Virology |
Artelinic acid 是水溶性青蒿素类似物,具有抗疟活性,用于治疗恶性疟原虫多重耐药菌株。 | |||
T19777 |
ODQ
|
Apoptosis; Others; Guanylate cyclase | Apoptosis; GPCR/G Protein; Others |
ODQ 是一种选择性可溶性的鸟苷酰环化酶抑制剂,可增强顺铂促人间皮瘤细胞凋亡的作用。 | |||
T19368 |
Hypromellose
Celacol HPM 5000,HPMC,羟丙甲纤维素,(Hydroxypropyl)methyl cellulose |
Others | Others |
Hypromellose (HPMC) 是一种水溶性的亲水性非离子纤维素醚。 | |||
T16808 |
Runcaciguat
|
Others; Guanylate cyclase | GPCR/G Protein; Others |
Runcaciguat 是一种可溶性鸟苷酸环化酶刺激剂。 Runcaciguat 与特异性部分腺苷 A1 受体激动剂相结合,可用于心血管和肾脏疾病的研究。 | |||
T15553 |
Iganidipine
NKY 722 |
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Iganidipine(NKY 722) 是一种新的水溶性 Ca2+ 拮抗剂,具有降压活性,可用于研究和神经系统相关的疾病。 | |||
T6775 |
BAY 41-2272
|
Guanylate cyclase | GPCR/G Protein |
BAY 41-2272 是一种直接且不依赖一氧化氮的可溶性鸟苷酸环化酶刺激剂。 | |||
T0947L |
Dexamethasone Phosphate disodium
地塞米松磷酸二钠,EGP-437,EGP437. Dex-Phos,EGP 437 |
Glucocorticoid Receptor | Endocrinology/Hormones |
Dexamethasone Phosphate disodium (EGP437. Dex-Phos) 是糖皮质激素受体激动剂。 | |||
T22425 |
Sevoflurane
七氟烷,Fluoromethyl |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Sevoflurane (Fluoromethyl) 是一种 5-HT3 受体的非竞争性抑制剂,是一种低溶性吸入麻醉剂。 | |||
T0271 |
Iodipamide
Iodipamic acid,胆影酸,Adipiodone |
Others | Others |
Iodipamide (Iodipamic acid) 是一种三碘苯甲酸酯衍生物,也是一种离子二聚剂,可用于诊断成像。 | |||
T17196 |
UC-1728
t-TUCB |
Epoxide Hydrolase | Metabolism |
UC-1728 (t-TUCB) 是一种兔子可溶性环氧化物水解酶抑制剂,兔子肝脏中测得其IC50=2 nM。 | |||
T0294 |
6α-Methylprednisolone 21-hemisuccinate sodium salt
Asmacortone,Methylprodnisolone Sodium Succinate,甲强龙琥珀酸钠,Metypresol,Methylprednisolone sodium succinate,Corticel,6-Methylprednisolone succinate sodium |
Glucocorticoid Receptor; Glucagon Receptor | Endocrinology/Hormones; GPCR/G Protein |
6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone) 是一种糖皮质激素,是一种有效的抗炎剂,半衰期比 Prednisolone 长。 | |||
T8734 |
Choline
|
Others | Others |
Choline hydroxide 是一种普遍存在的水溶性营养素,通常与 B 族维生素有关。 | |||
T3311 |
GSK6853
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
GSK6853 是一种强选择性RPF1乙酰赖氨酸抑制剂,pKd 为9.5,其选择性是其它的乙酰赖氨酸的 1600 倍。 | |||
T13365 |
YHO-13351 free base
|
BCRP | Membrane transporter/Ion channel |
YHO-13351 free base 是 YHO-13177 的水溶性前药,YHO-13177 是 BCRP 的抑制剂。 | |||
T7551 |
Belotecan hydrochloride
CKD-602 |
Topoisomerase | DNA Damage/DNA Repair |
Belotecan hydrochloride (CKD-602) 是一种合成的水溶性喜树碱衍生物和拓扑异构酶 I 抑制剂,具有潜在的抗肿瘤活性。 | |||
TQ0101 |
MKC3946
|
IRE1 | Cell Cycle/Checkpoint |
MKC3946 是一种有效的可溶性 IRE1α 抑制剂,可在多发性骨髓瘤细胞系中引发适度的生长抑制,可用于癌症研究。 | |||
TNU0864 |
HUP30
|
Potassium Channel; Calcium Channel | Membrane transporter/Ion channel; Metabolism |
HUP30是一种强效的血管舒张剂。HUP30可以刺激可溶性鸟苷酸环化酶,激活 K+离子通道,阻断细胞外 Ca2+的内流。 | |||
T0752 |
Ascorbyl palmitate
L-抗坏血酸棕榈酸酯,L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate,抗坏血酸棕榈酸酯 |
Reactive Oxygen Species; Endogenous Metabolite | Immunology/Inflammation; Metabolism; NF-κB |
Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate) 是由抗坏血酸和棕榈酸形成的一种酯,一种脂溶性形式的维生素 C。 | |||
T68019L |
Ursulcholic acid trisodium salt
Ursodeoxycholic acid disulfate trisodium salt,Ursulcholic acid trisodium salt(88426-32-8 Free base) |
Others | Others |
Ursulcholic acid trisodium salt (Ursodeoxycholic acid disulfate trisodium salt) 是 ursodeoxycholic acid 的可溶形式,ursodeoxycholic acid 具有抗高血脂和利胆活性活性。 | |||
T8834 |
EST64454 hydrochloride
EST64454 |
Sigma receptor | GPCR/G Protein |
EST64454 hydrochloride (EST64454) 是一种可口服的选择性sigma-1受体拮抗剂,Ki 为 22 nM。它有用于疼痛的研究潜力。 | |||
T22830 |
GYY4137
GYY 4137 morpholine salt |
Others | Others |
GYY4137 (GYY 4137 morpholine salt) 是一种缓释H2S 供体,具有抗炎和抗癌作用,也具有血管扩张和抗高血压活性。 | |||
T8459 |
DNQX disodium salt
DNQX Disodium |
NMDAR; iGluR | Membrane transporter/Ion channel; Neuroscience |
DNQX disodium salt 是一种选择性、强竞争性的非 NMDA 谷氨酸受体 (non-NMDA glutamate receptor) 拮抗剂 (对 AMPA、kainate 和 NMDA 受体的 IC50分别为 0.5、2 和 40 μM),是一种喹恶啉衍生物。 | |||
T4381 |
Lificiguat
利非西呱,YC-1 |
Others; Guanylate cyclase; HIF | Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein; Others |
Lificiguat (YC-1) 是一种不依赖一氧化氮的可溶性鸟苷酸环化酶激活剂和低氧诱导因子 1α 的抑制剂。 | |||
T9306 |
EST64454 Maleic acid salt
|
Others | Others |
EST64454 Maleic acid salt 是EST64454的马来酸盐形式。EST64454是一种用于治疗疼痛的高可溶性σ1受体拮抗剂临床候选药物。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12297 |
Oleuropeinic acid
|
Others | Others |
Oleuropeinic acid 是一种抗氧化剂可溶性纤维,存在于橄榄组织中或通过热处理形成,可能是由橄榄苦苷的氧化形成。 | |||
TN6794 |
N-(3-methoxybenzyl)-octadecanamide
|
Others | Others |
N-(3-methoxybenzyl)-octadecanamide 从玛卡 (Lepidium meyenii Walp.) 转化而来。 | |||
T1116 |
Biotin
Vitamin B7,生物素,D-Biotin,Vitamin H,D-生物素(维生素H) |
||
Biotin (Vitamin H) 是一种水溶性B族维生素,是细胞生长、脂肪酸产生以及脂肪和氨基酸代谢所必需的。 | |||
T9368 |
3,4-(Methylenedioxy)cinnamic acid
3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid,3,4-(亚甲二氧)肉桂酸 |
Others | Others |
3,4-(Methylenedioxy)cinnamic acid (3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid) 是一种植物衍生化合物,首先从芦笋的根中提取,并进一步表征为一种化感化学物质。 | |||
TN2174 |
Salvianolic acid E
丹酚酸 E,丹酚酸E |
Others | Others |
Salvianolic acid E 是一种从丹参 Salvia miltiorrhiza 中分离出来的水溶性成分。 | |||
T1075 |
Vitamin K1
Phylloquinone,维生素K1,叶绿醌,Phytomenadione,Phytonadione,Phyllohydroquinone |
Others; Endogenous Metabolite | Metabolism; Others |
Vitamin K1 (Phylloquinone)是天然存在的维生素。Vitamin K1是血液凝固,骨和血管代谢所必须的。 | |||
T2989 |
4-Hydroxybenzoic acid
p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate |
Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology |
4-Hydroxybenzoic acid (4-hydroxybenzoate) 是苯甲酸的酚衍生物,可抑制革兰氏阳性和革兰氏阴性菌,IC50值为160 μg/mL。 | |||
T19224 |
C-Phycocyanin
C-PC,藻蓝蛋白,C-藻蓝蛋白 |
Others | Others |
C-Phycocyanin (C-PC) 是一种蛋白质色素,常作为人类的优良营养补充剂。 | |||
T3551 |
D-Pantothenic acid hemicalcium salt
泛酸钙,D-Pantothenic Acid Calcium,D-泛酸半钙,Calpanate,Calcium D-pantothenate,Vitamin B5 calcium salt,Calcium pantothenate,Calcium D-Panthotenate |
Apoptosis; Endogenous Metabolite | Apoptosis; Metabolism |
D-Pantothenic acid hemicalcium salt (Calcium pantothenate) 是一种水溶性维生素,能够减少苹果汁中的棒曲霉素。 | |||
T17303 |
α-Cyclodextrin
Alfadex,NSC269470,α-环糊精,NSC 269470,NSC-269470 |
Others | Others |
α-Cyclodextrin (Alfadex) 是一种多功能可溶性膳食纤维,可作为纤维原料销售。 | |||
T1648 |
α-Vitamin E
天然维生素E,Dexrabeprazole Sodium,Vitamin E,Alpha-Tocopherol,D-α-Tocopherol,5,7,8-Trimethyltocol,D-α-生育酚,(+)-alpha-Tocopherol |
Others; Ferroptosis; Influenza Virus; Reactive Oxygen Species; Endogenous Metabolite; Antibacterial; PKC; GST | Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others; oxidation-reduction |
α-Vitamin E (Dexrabeprazole Sodium) 是一种天然存在的维生素 E,也是抗氧化剂。 | |||
T4760 |
KSD 2405
3-羟基苯甲醇,3-Hydroxybenzyl alcohol |
Others; Endogenous Metabolite | Metabolism; Others |
KSD 2405 (3-Hydroxybenzyl alcohol) 是内源性代谢产物的一种。 | |||
TN2364 |
Sudan IV
苏丹红Ⅳ,Solvent Red 24,C.I. 26105 |
Others | Others |
Sudan IV (Solvent Red 24) 是脂溶性重氮染料,可用于冰冻或石蜡切片上,能够将脂类、甘油三酯和脂蛋白染色。 | |||
T4107 |
4-Pyridoxic Acid
4-吡哆酸,Pyridoxic Acid,4-Pyridoxinsaeure |
Endogenous Metabolite | Metabolism |
4-Pyridoxic Acid (4-Pyridoxinsaeure) 是一种维生素B6的分解代谢产物,从尿液中分泌得到。 | |||
T5068 |
D-Glucuronic acid sodium salt monohydrate
Sodium D-glucuronate,D-葡糖醛酸钠一水,D-葡萄糖醛酸钠,D(+)-Glucuronic acid sodium salt monohydrate |
Others; Endogenous Metabolite | Metabolism; Others |
D-Glucuronic acid sodium salt monohydrate (Sodium D-glucuronate) 是内源性代谢产物的一种。 | |||
T5725 |
Salvianolic acid B
丹酚酸B,lithospermic acid B,Dan Shen Suan B |
Sirtuin; Autophagy | Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair |
Salvianolic acid B (Dan Shen Suan B) 是一种来自丹参提取物的水溶性抗氧化剂,具有抗血小板聚集、抗凝和抗血栓作用。它常用来研究微循环疾病。 | |||
T5258 |
Dodecanedioic acid diammonium salt
十二烷二酸 二铵盐,1,10-Decanedicarboxylic acid diammonium salt |
Others | Others |
Dodecanedioic acid diammonium salt (1,10-Decanedicarboxylic acid diammonium salt) 是一种二元羧酸,它是水溶性的,并且参与了脂类和碳水化合物的代谢途径中间体。 | |||
T5311 |
Crocin (Gardenia Fruits Extract)
藏红花,西红花苷 |
Others | Others |
Crocin (Gardenia Fruits Extract)(42553-65-1)是藏红花(Crocus sativus L.)的水溶性类胡萝卜素色素。藏红花素具有抗炎、抗氧化、抗凋亡、抗哮喘、抗癌、降血脂等作用。 | |||
T4784 |
(S)-(-)-Phenylethanol
(S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol |
Others; Endogenous Metabolite | Metabolism; Others |
(S)-(-)-Phenylethanol ((-)-Methyl phenyl carbinol) 是内源性代谢产物的一种。 | |||
T2727 |
Salvianolic acid B
|
Others | Others |
Salvianolic acid B (Dan Shen Suan B) 是一种来自丹参提取物的水溶性抗氧化剂,具有抗血小板聚集、抗凝和抗血栓作用。它常用来研究微循环疾病。 | |||
T2719 |
Succinic acid
Asuccin,Amber acid,琥珀酸,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid |
Endogenous Metabolite | Metabolism |
Succinic acid (1,2-Ethanedicarboxylic acid) 是无氧代谢的发酵产物,也是三羧酸循环的中间产物。 | |||
T3368 |
Alpha-Hederin
α常春藤皂甙,Helixin,Tauroside E,α-Hederin,Hederoside C |
Apoptosis; Others | Apoptosis; Others |
Alpha-Hederin (Tauroside E) 是存在于黑种草种子中的一种单桥糖三萜皂苷,具有抗肿瘤作用。它可通过激活线粒体依赖性途径抑制胃癌细胞增殖,诱导凋亡,并有活性氧生成和谷胱甘肽减少。 | |||
T0433 |
Artesunate
WR-256283,青蒿琥酯 |
Virus Protease; Ferroptosis; STAT; Parasite | Apoptosis; JAK/STAT signaling; Microbiology/Virology; Stem Cells |
Artesunate (WR-256283) 是治疗疟疾的青蒿素组药物的一部分。 它是青蒿素的半合成衍生物,具有水溶性。 | |||
T5082 |
Calcium 2-hydroxy-4-(methylthio)butanoate
羟基蛋氨酸钙,calcium hydroxymethionine,2-Hydroxy-4-(methylthio)butyric acid calcium salt |
Others; Endogenous Metabolite | Metabolism; Others |
Calcium 2-hydroxy-4-(methylthio)butanoate (Calcium 2-hydroxy-4-(calcium hydroxymethionine)) 是内源性代谢产物的一种。 | |||
T11060 |
DMAPT
Dimethylamino Parthenolide |
NF-κB | NF-κB |
DMAPT (Dimethylamino Parthenolide) 是一种具有口服活性的NF-κB 抑制剂,是一种 Parthenolide (PTL) 的类似物,对原发性急性髓性白血病细胞的LD50值为1.7 μM。具有潜在的抗肿瘤和抗转移作用。 | |||
T1353 |
DL-Mevalonolactone
甲瓦龙酸内酯,Mevalonolactone |
Others; Endogenous Metabolite | Metabolism; Others |
DL-Mevalonolactone (Mevalonolactone),一种人内源性代谢物,是甲羟戊酸的 δ-lactone 形式,甲羟戊酸途径的一个前体。它能够降低大脑中线粒体膜电位(∆Ψm),Ca2+的保留能力和 NAD (P) H 的含量 , 而且还诱导线粒体肿胀。 | |||
T2946 |
Tanshinone IIA sulfonate sodium
丹参酮IIA磺酸盐,丹参酮IIA-磺酸钠,Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium |
CaMK; P450; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Neuroscience |
Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) 是从丹参中提取的丹参酮IIA 的水溶性衍生物,是SOCE 抑制剂,用于心血管疾病的研究。 | |||
T6272 |
Fosbretabulin Disodium
Combretastatin A4 Phosphate,CA 4DP,CA 4P,福他布林,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Fosbretabulin Disodium (CA 4P) 是一种微管蛋白去稳定剂,是 Combretastatin A4 前药,可选择性靶向内皮细胞,诱导新生肿瘤新血管消退,减少肿瘤血流量并引起中央肿瘤坏死。 | |||
T3946 |
Octanoic acid
Caprylic acid,辛酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Octanoic acid (Caprylic acid) 天然存在于椰子和母乳中。它是一种油性液体,带有些许腐臭味,能用于酯类香料和染料的生产。 | |||
T3739 |
2,6-Dimethoxyquinone
2,6-Dimethoxy-1,4-benzoquinone,2,6-Dimethoxy-p-benzoquinone,2,6-Dimethoxybenzoquinone,2,6-二甲氧基-1,4-苯醌 |
Others | Others |
2,6-Dimethoxyquinone (2,6-Dimethoxy-p-benzoquinone) 是一种植物中提取吸脂诱导因子。它具有抗脂肪、抗癌、抗菌、抗疟疾和抗炎的作用。 | |||
T0879 |
Niacin
Vitamin B3,烟酸(维生素B3),Nicotinic acid |
Endogenous Metabolite; Autophagy | Autophagy; Metabolism |
Niacin (Nicotinic acid),也称为烟酸和维生素 B3,是一种水溶性必需的 B 族维生素,用于治疗维生素缺乏症以及高脂血症,血脂异常,高甘油三酯血症,并降低心肌梗塞的风险 | |||
T0883 |
Tramiprosate
Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸 |
Beta Amyloid; GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Tramiprosate (Alzhemed) 是一种具有口服活性的、可透过血脑屏障的天然氨基酸,存在于各种红色海藻中,能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物,具有神经保护,抗惊厥和抗高血压的活性。 | |||
T4773 |
3-Ethoxy-3-oxopropanoic acid
Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯 |
Others; Endogenous Metabolite | Metabolism; Others |
3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) 是内源性代谢产物的一种。 | |||
T2818 |
Methyl Vanillate
|
Reactive Oxygen Species; Wnt/beta-catenin; Endogenous Metabolite | Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells |
Methyl vanillate 是一种枳椇属植物中的提取物,是Wnt/β-catenin 信号通路活化剂,是一种香草酸的甲酯。它具有抗氧化作用。 | |||
T4768 |
Diethyl oxalpropionate
草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE |
Others; Endogenous Metabolite | Metabolism; Others |
Diethyl oxalpropionate (HYL 2-METHYL-3-OXOSUCCINATE) 是一种合成 PDMMLA 的中间体。其中 PDMMLA 的衍生物可用于纳米粒子的合成和研究。 | |||
Fr13883 |
3-Methoxyphenylacetic acid
|
Others | Others |
3-Methoxyphenylacetic acid 是 m-hydroxyphenylacetic (m-OHPAA) 的衍生物,茄形假丝酵母中的一种植物毒素。它可用于针对介氧菌根腐烂的毒素介导的生物测定法的开发。 | |||
T3947 |
Nonanoic acid
pelargonic acid,Nonoic acid,壬酸 |
Others; Antibacterial | Microbiology/Virology; Others |
Nonanoic acid (Nonoic acid) 是一种天然存在的具有九个碳原子的饱和脂肪酸。它减少细菌易位,增强抗菌活性,并增加猪 β-防御素 1 (pBD-1) 和 pBD-2 的分泌。 | |||
T6480 |
D-Pantothenic acid
vitamin B5,pantothenate,D-泛酸 |
Others | Others |
D-Pantothenic acid (vitamin B5) 是必需的微量营养素,是辅酶 A 的前体,在很多生物过程中发挥关键作用,如调节碳水化合物,脂质,蛋白和核酸代谢。 | |||
T1040 |
Vitamin B12
Cyanocobalamin,Cobalamin,维生素B12 |
Endogenous Metabolite | Metabolism |
Vitamin B12 (Cobalamin) 是一种维生素,在维持血流形成和脑、神经系统正常功能等方面发挥关键作用。 | |||
T2823 |
Crocin
西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素 |
Others | Others |
Crocin (Gardenia Yellow) 是从Crocus sativus 柱头中分离出的主要成分,是一种营养保健品,具有抗炎,抗癌,抗抑郁和抗惊厥等强大的药理作用。 | |||
T4798 |
N-Acetyl-L-leucine
|
Others; Endogenous Metabolite | Metabolism; Others |
N-Acetyl-L-leucine 是内源性代谢产物的一种。 | |||
TJO2758 |
D-Glucuronic acid
D-葡萄糖醛酸,Aldehydo-D-Glucuronic Acid |
Others; Endogenous Metabolite | Metabolism; Others |
D-Glucuronic acid (Aldehydo-D-Glucuronic Acid) 是一种从许多树胶中分离出的重要中间体。它对皮肤具有抗炎作用。它及其衍生物葡萄糖醛酸内酯作为预防人类健康的肝脏解毒剂。 | |||
T1331 |
Riboflavin phosphate sodium
Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate |
Endogenous Metabolite | Metabolism |
Riboflavin phosphate sodium (FMN) 是 riboflavin 的磷酸钠盐形式,riboflavin 是一种水溶性和必需的微量营养素,是自然产生的维生素B复合物的主要生长促进因子。Riboflavin phosphate sodium 转化为2种辅酶,黄素单核苷酸(FMN)和黄素腺嘌呤二核苷酸(FAD),这两种辅酶通过帮助脂肪、碳水化合物和蛋白质的代谢来产生能量,并且是红细胞形成和呼吸、抗体产生以及调节人体生长和繁殖所必需的。 | |||
T2163 |
Dihydrocapsaicin
CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide |
Others; TRP/TRPV Channel | Membrane transporter/Ion channel; Others |
Dihydrocapsaicin (CCRIS1589) 是一种天然来源的辣椒素,是TRPV1的选择性激动剂,同时可以增加 p-Akt 水平。它可以增强低温诱导的神经保护。 | |||
T4837 |
Itaconic acid
methylene-butanedioicaci,衣康酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Itaconic acid (methylene-butanedioicaci) 是聚合物,化学物质和燃料的合成前体。Itaconic acid 可由真菌合成。它也是巨噬细胞特异性代谢产物。它介导巨噬细胞代谢和腹膜肿瘤之间的串扰。 | |||
T13777 |
Moniliformin sodium salt
|
Others | Others |
Moniliformin sodium salt is water-soluble mycotoxin isolate from Fusarium moniliforme. | |||
T32740 |
Libramycin A
|
||
Libramycin A is a fat-soluble, weakly acidic substance extracted from Streptomyces. | |||
T34489 |
Salicifoline
|
||
Salicifoline is a water-soluble quaternary ammonium alkaloid. | |||
T29888 |
Aloe-emodin-glucoside
|
||
Aloe-emodin-glucoside is a stimulant-laxative which has been shown to enhance colonic membrane permeability of water-soluble and poorly permeable compounds. | |||
T0879L |
Niacin hydrochloride
|
||
Niacin hydrochloride is a water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is needed by the body for the formation of coenzymes NAD and NADP. It possesses PELLAGRA-curative, vasodilating, and antilipemic properties. | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04989 |
Galectin-9 Protein, Human, Recombinant (hFc)
LGALS9A,lectin, galactoside-binding, soluble, 9,HUA... |
Human | HEK293 Cells |
LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or i... | |||
TMPJ-00387 |
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Soluble IL-4R-alpha,Interleukin-4 receptor subunit ... |
Mouse | HEK293 Cells |
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ... | |||
TMPY-03565 |
Mannan Binding Lectin/MBL2 Protein, Human, Recombinant
MBPD,MBP-C,mannose-binding lectin (protein C) 2, soluble... |
Human | CHO Cells |
Mannan Binding Lectin/MBL2 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 24 kDa and the accession number is P11226. | |||
TMPY-02131 |
Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)
acid phosphatase 1, soluble,HAAP |
Human | E. coli |
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of important physiological functions, including stress resistance and synthesis of the polysaccharide capsule. ACP1/LMW-PTP is an enzyme involved in platelet-derived growth factor-induced mitogenesis and cytoskeleton rearrangement. LMW-PTP is able to specifically bind and dephosphoryl... | |||
TMPY-04109 |
Galectin-7 Protein, Human, Recombinant (His)
lectin, galactoside-binding, soluble, 7,LGALS7A,GAL... |
Human | E. coli |
Galectin-7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.2 kDa and the accession number is P47929. | |||
TMPY-02599 |
MDH1 Protein, Rat, Recombinant (His)
malate dehydrogenase 1, NAD (soluble) |
Rat | E. coli |
Malate dehydrogenases 1(MDH1 / MDHA) is a soluble form of malate dehydrogenases. Malate dehydrogenases (MDH) is a group of multimeric enzymes consisting of identical subunits usually organized as either dimer or tetramers with subunit molecular weights of 30-35 kDa. MDH has been isolated from different sources including archaea, eubacteria, fungi, plants, and mammals. MDH catalyzes the NAD/NADH-dependent interconversion of the substrates malate and oxaloacetate. This reaction plays a key part in... | |||
TMPY-03131 |
Galectin-1 Protein, Rat, Recombinant
lectin, galactoside-binding, soluble, 1 |
Rat | E. coli |
Galectin-1 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P11762. | |||
TMPY-02773 |
Galectin-8 Protein, Rat, Recombinant (GST)
lectin, galactoside-binding, soluble, 8 |
Rat | E. coli |
Galectin-8 Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 63.2 kDa and the accession number is Q6IN24. | |||
TMPY-03755 |
Glycerol 3 Phosphate Dehydrogenase/GPD1 Protein, Human, Recombinant (His)
GPDH-C,HTGTI,GPD-C,glycerol-3-phosphate dehydrogenase 1 ( |
Human | E. coli |
GPD1 (Glycerol-3-Phosphate Dehydrogenase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. GPD1 is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. It also reduces nicotine adenine dinucleotide... | |||
TMPY-00976 |
Galectin-1 Protein, Human, Recombinant
GBP,Galectin-1,lectin, galactoside-binding, soluble... |
Human | E. coli |
Galectin-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is A0A384MR27. | |||
TMPJ-01351 |
XPNPEP1 Protein, Human, Recombinant (His)
Xaa-Pro Aminopeptidase 1,X-Prolyl Aminopeptidase 1 Solub... |
Human | E. coli |
X-Prolyl Aminopeptidase (XPNPEP1) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-Prolyl Aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby compleme... | |||
TMPY-02774 |
Galectin-7 Protein, Human, Recombinant (GST)
LGALS7A,lectin, galactoside-binding, soluble, 7,GAL... |
Human | E. coli |
Galectin-7 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 41.8 kDa and the accession number is P47929. | |||
TMPY-02482 |
Aconitase 1 Protein, Human, Recombinant (His)
HEL60,IRP1,ACONS,aconitase 1, soluble,IREBP,IREBP1,... |
Human | Baculovirus Insect Cells |
Aconitase 1(ACO1) or IRP1 is one member of the aconitase family that contains a diverse group of iron-sulphur(Fe-S) isomerases and two types of iron regulatory protein. Aconitase exits in two forms: one is soluble and the other is mitochondrial. ACO1 is the soluble existing form, and the mitochondrial form is ACO2. Residues from all three N-terminal domains and the larger C-terminal domain contribute to the active site region. When the enzyme is activated, it gains an additional iron atom. ACO1 ... | |||
TMPY-06685 |
Galectin-1 Protein, Human, Recombinant (His)
GBP,GAL1,lectin, galactoside-binding, soluble, 1,Ga... |
Human | E. coli |
Galectin-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.07 kDa and the accession number is NP_002296.1. | |||
TMPY-00429 |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc)
MBL-C,mannose-binding lectin (protein C) 2, soluble... |
Mouse | HEK293 Cells |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 50.6 kDa and the accession number is P41317. | |||
TMPY-04322 |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His)
MBL-C,MBL,mannose-binding lectin (protein C) 2, soluble<... |
Mouse | HEK293 Cells |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P41317. | |||
TMPY-03445 |
Aspartate Aminotransferase Protein, Human, Recombinant (His)
ASTQTL1,glutamic-oxaloacetic transaminase 1, soluble |
Human | E. coli |
GOT1 (Glutamic-Oxaloacetic Transaminase 1) is a Protein Coding gene. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme that exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. GOT1 is an important regulator of levels of glut... | |||
TMPY-02611 |
Galectin-8 Protein, Human, Recombinant
lectin, galactoside-binding, soluble, 8,PCTA-1,Po66... |
Human | E. coli |
Galectin-8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 35.5 kDa and the accession number is AAF19370.1. | |||
TMPY-02326 |
Galectin-8 Protein, Human, Recombinant (GST)
PCTA1,Po66-CBP,PCTA-1,lectin, galactoside-binding, solub... |
Human | E. coli |
Galectin-8 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 62.7 kDa and the accession number is AAF19370.1. | |||
TMPY-02319 |
Galectin-3 Protein, Human, Recombinant
GALBP,CBP35,GAL3,GALIG,MAC2,LGALS2,lectin, galactoside-bindi... |
Human | E. coli |
LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through... | |||
TMPJ-00642 |
TIE2 Protein, Human, Recombinant (hFc)
TEK tyrosine kinase, endothelial,EC 2.7.10,Tie2,hTIE2,p140 T... |
Human | HEK293 Cells |
TIE2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession number is Q02763-1. | |||
TMPY-01585 |
SOD1 Protein, Human, Recombinant (His)
SOD,homodimer,ALS,hSod1,IPOA,superoxide dismutase 1, sol... |
Human | E. coli |
SOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.... | |||
TMPY-02102 |
Galectin-1 Protein, Mouse, Recombinant
L-14.5,Galbp,AA410090,lectin, galactoside-binding, solub... |
Mouse | E. coli |
Galectin-1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is P16045. | |||
TMPJ-00643 |
TIE2 Protein, Human, Recombinant (aa 23-745, His)
VMCM1,TEK,Tie2,hTIE2,p140 TEK,soluble TIE2 variant ... |
Human | HEK293 Cells |
TIE2 Protein, Human, Recombinant (aa 23-745, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is Q02763-1. | |||
TMPY-02330 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, hFc)
Cd137,A930040I11Rik,tumor necrosis factor receptor superfami... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47 kDa and the accession number is Q8R037. | |||
TMPY-05031 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, His)
CDw137,4-1BB,AI325004,A930040I11Rik,Cd137,ILA,tumor necrosis... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q8R037. | |||
TMPY-04995 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, rFc)
A930040I11Rik,tumor necrosis factor receptor superfamily, me... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 46.1 kDa. | |||
TMPY-02413 |
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His)
HEL-S-26,HEL-216,IDP,IDCD,PICD,IDH,isocitrate dehydrogenase ... |
Human | E. coli |
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 48 kDa and the accession number is O75874. | |||
TMPJ-01105 |
MPF Protein, Human, Recombinant (His)
SMR,Pre-pro-megakaryocyte-potentiating factor,mesothelin,MSL... |
Human | HEK293 Cells |
MPF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is Q13421. | |||
TMPY-06528 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)
tumor necrosis factor receptor superfamily, member 9,4-1BB,C... |
Human | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.70 kDa and the accession number is Q07011. | |||
TMPJ-01104 |
MPF Protein, Human, Recombinant (hFc)
SMR,CAK1,CAK1 antigen,Pre-pro-megakaryocyte-potentiating fac... |
Human | HEK293 Cells |
MPF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 KDa and the accession number is Q13421. | |||
TMPJ-00021 |
LGALS1 Protein, Human, Recombinant (His)
HPL,S-Lac Lectin 1,Lactose-Binding Lectin 1,14 kDa Lectin,Be... |
Human | E. coli |
Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domains. Galectin-1 can binds LGALS3BP and interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Galectin-1 may act as an autocrine negative growth factor which regulates apoptosis, cell proliferation and cell differentiation. In addition, Galectin-1 plays improtant roles in immunosuppress... | |||
TMPJ-00119 |
IL-22RA2 Protein, Human, Recombinant (hFc)
Cytokine Receptor Family 2 Member 10,CRF2-10,IL-22RA2,Interl... |
Human | HEK293 Cells |
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described. | |||
TMPJ-01099 |
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece... |
Human | HEK293 Cells |
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun... | |||
TMPY-03758 |
Vaccinia Virus B18R/B19R Protein (His)
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VACV | Baculovirus Insect Cells |
B18R is a type I interferon (IFN)-binding protein, which is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus. It is also known as B19R in the Copenhagen strain of Vaccinia. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R has a broad species specificity. It has high affinity for human IFN-alpha and also binds rabbit, bovine, rat, pig, and mouse IFN-alpha and IFN-beta. It has been shown that secreted B18R binds to un... | |||
TMPK-01393 |
Tenascin Protein, Mouse, Recombinant (His)
Hexabrachion,Hxb,TN-C,TN,TNC,Tenascin-C |
Mouse | HEK293 Cells |
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tena... | |||
TMPK-01392 |
Tenascin Protein, Human, Recombinant (His)
Tenascin-C,TNC,TN,Hexabrachion,Hxb,TN-C |
Human | HEK293 Cells |
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tena... | |||
TMPY-03425 |
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ... |
Human | E. coli |
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... | |||
TMPY-02204 |
LBP Protein, Human, Recombinant (His)
BPIFD2,lipopolysaccharide binding protein |
Human | HEK293 Cells |
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end... | |||
TMPJ-00137 |
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
TRDL-1,TNF- and APOL-related leukocyte expressed ligand 2,Tu... |
Human | HEK293 Cells |
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept... | |||
TMPK-00840 |
CD21 Protein, Mouse, Recombinant (His)
C3DRSLEB9,CR2,CVID7,C3DR,CD21,SLEB9,EBV receptor |
Mouse | HEK293 Cells |
A natural soluble form of CD21 that is cleaved from lymphocyte membrane CD21 circulates in normal human serum. Soluble CD21 retains the capacity to bind iC3b and CD23, the known ligands of membrane CD21. In a similar fashion to IgE complexes, another ligand of CD23, the soluble CD21 was shown to efficiently trigger CD23-signalling pathways in human monocytes. | |||
TMPH-00658 |
NAD(P)H-flavin reductase Protein, E. coli, Recombinant (His)
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E. coli | E. coli |
Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides. | |||
TMPY-04152 |
RAB7A Protein, Rat, Recombinant (His)
RAB7A, member RAS oncogene family,Rab7 |
Rat | E. coli |
RAB7A is a ubiquitous small GTPase, which controls transport to late endocytic compartments. Silencing or overexpression of wild type RAB7A changed the soluble/insoluble rate of peripherin indicating that RAB7A is important for peripherin organization and function. Besides, disease-causing RAB7A mutant proteins bind more strongly to peripherin and their expression causes a significant increase in the amount of soluble peripherin. The altered interaction between disease-causing RAB7A mutants and ... | |||
TMPH-03321 |
KRTDAP Protein, Rat, Recombinant (His & SUMO)
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Rat | E. coli |
May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis. KRTDAP Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 21.5 kDa and the accession number is P85411. | |||
TMPH-00771 |
Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO)
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Glycine max | E. coli |
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. | |||
TMPH-03230 |
PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His)
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Ralstonia pickettii | E. coli |
This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate. PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P12625. | |||
TMPJ-00546 |
EFNA1 Protein, Human, Recombinant (hFc)
TNFAIP4,LERK1,Tumor Necrosis Factor α-Induced Protein 4,Imme... |
Human | HEK293 Cells |
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the... | |||
TMPY-02025 |
CPLX2 Protein, Human, Recombinant (His)
CPX-2,Hfb1,921-L,complexin 2,CPX2 |
Human | E. coli |
Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Complexins are unable to bind to monomeric SNARE proteins but bind with high affinity to ternary SNARE complexes and with lower affinity to target ... | |||
TMPK-01267 |
TREM-1 Protein, Cynomolgus, Recombinant (His)
CD354,TREM-1 |
Cynomolgus | HEK293 Cells |
TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear. | |||
TMPK-00377 |
DPPIV/CD26 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
DPP4,DPPIV,ADCP2,CD26,ADABP,TP103,EC 3.4.14.5 |
Cynomolgus,Rhesus | HEK293 Cells |
CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express DPPIV/CD26 to a variable extent. | |||
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