gland

Chlorphenesin (Chlorophenesin) 是一种抗原相关免疫抑制剂，可抑制 IgE 介导的组胺释放。 它也用作抗真菌剂，用于许多眼保健化妆品中。

Epidermal Growth Factor, murine submaxillary gland 是从小鼠颌下腺中提取的生物活性多肽。此化合物作为有丝分裂原，在多种实验条件下可促进上皮细胞、成纤维细胞和神经胶质细胞的生长。

Nerve Growth Factor 2.5S, murine submaxillary gland 是一种神经营养多肽，对于中枢神经系统中的交感神经、胚胎感觉神经元和某些胆碱能神经元的正常生长发育至关重要。Nerve Growth Factor 2.5S, murine submaxillary gland 仅含 β 亚基，并具有促进神经生长的活性。

Nerve Growth Factor 7S, murine submaxillary gland 是一种 α2β2γ2 复合物，由 β-NGF 二聚体（活性神经营养因子）和两个 α-NGF 及两个 γ-NGF 亚基组成。

Tetracosactide (Tetracosactrin) 是一种肾上腺皮质激素 (ACTH) 的类似物，能够刺激肾上腺皮质激素分泌。

Acetylcholine chloride (Pilofrin) 是一种神经递质，是胆碱能激动剂，通过刺激烟碱乙酰胆碱受体调节多巴胺能神经元活性，在体外抑制 p53 突变肽的聚集。

Tetracosactide acetate 是一种合成的多肽，可刺激肾上腺释放皮质类固醇 ，如皮质醇。Tetracosactide acetate 在溃疡性结肠炎和克罗恩病、青少年和成人类风湿性关节炎和骨关节病方面有研究的价值。

Prostaglandin E2 (PGE2) 是一种天然激素，参与人体内的各种生理过程，包括平滑肌收缩和放松、调节血管扩张和收缩、调节血压和炎症调节。

Prostaglandin G H synthase 1 inhibitor (CP 74006) 是一种选择性D5D 抑制剂，IC(50)值为20nM。

Prostaglandin E1 (Alprostadil) 是一种前列腺素受体配体，对小鼠 EP1、EP2、EP3、EP4和 IP 的 Ki 值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集，可作为血管扩张剂用于外周血管疾病的研究。

1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid . 1a,1b-dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid . This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.

16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2 EP4 and has an interaction with the Wnt pathway.

Eglandulosine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124699，CAS号为 53508-33-1。

Prostaglandin D2 (PGD2) (PGD2) 是哺乳动物大脑中主要产生的前列腺素之一，为最有效的内源性睡眠促进剂之一，并通过抑制炎症发挥保护作用。

Prostaglandin K1 (compound 46) 是结构修饰的前列环素 (prostanoid) 类似物，针对EP1的EC50和Ki均为2800 nM。

15-deoxy-Δ-12,14-Prostaglandin J2 is a PPARγ agonist.

Levuglandin E2 is a secoprostanoid from prostaglandin endoperoxide.

Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacological studies on 15-keto-17-phenyl trinor PGF2α ethyl amide have been reported.

PGBx is a mixture of oligomers of PGB1 with a molecular weight of 1,000-1,500. It has antioxidant and free radical trapping activity that was first studied in isolated mitochondria.1 PGBx has anti-inflammatory and cytoprotective activity which may be attributed to inhibition of the 14 kDa sPLA2.2,3 At a dose of 1 mg/kg, PGBx significantly reduces the incidence of ulcers in rats.2References1. Polis, B.D., Polis, E., and Kwong, S. Protection and reactivation of oxidative phosphorylation in mitochondria by a stable free-radical prostaglandin polymer (PGBΧ). Proceedings of the National Academy of Sciences of the United States of America 76, 1598-1602 (1979).2. Kumashiro, R., Devlin, T.M., Kholoussy, A.M., et al. Prostaglandin BΧ in the prevention of stress ulcers in rats. International Surgery 70, 247-250 (1985).3. Franson, R.C., Rosenthal, M.D., and Regelson, W. Mechanism(s) of cytoprotective and anti-inflammatory activity of PGB1 oligomers: PGBx has potent anti-phospholipase A2 and anti-oxidant activity. Prostaglandins, Leukotrienes and Essential Fatty Acids 43, 63-70 (1991). PGBx is a mixture of oligomers of PGB1 with a molecular weight of 1,000-1,500. It has antioxidant and free radical trapping activity that was first studied in isolated mitochondria.1 PGBx has anti-inflammatory and cytoprotective activity which may be attributed to inhibition of the 14 kDa sPLA2.2,3 At a dose of 1 mg/kg, PGBx significantly reduces the incidence of ulcers in rats.2 References1. Polis, B.D., Polis, E., and Kwong, S. Protection and reactivation of oxidative phosphorylation in mitochondria by a stable free-radical prostaglandin polymer (PGBΧ). Proceedings of the National Academy of Sciences of the United States of America 76, 1598-1602 (1979).2. Kumashiro, R., Devlin, T.M., Kholoussy, A.M., et al. Prostaglandin BΧ in the prevention of stress ulcers in rats. International Surgery 70, 247-250 (1985).3. Franson, R.C., Rosenthal, M.D., and Regelson, W. Mechanism(s) of cytoprotective and anti-inflammatory activity of PGB1 oligomers: PGBx has potent anti-phospholipase A2 and anti-oxidant activity. Prostaglandins, Leukotrienes and Essential Fatty Acids 43, 63-70 (1991).

Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.

Enzymatically-derived prostaglandin E2 (PGE2) is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGE2 is the opposite enantiomer of PGE2. Significant amounts of racemic PGE2 (rac-PGE2) are generated in vitro and in vivo in settings of oxidative stress via the isoprostane pathway. A proposed mechanism for the formation of rac-PGE2 involves the base catalyzed equilibration from 15-E2t-isoprostane (8-iso-PGE2), generated from the 15-H2t-isoprostane endoperoxide.

ent-Prostaglandin F2α 是 PGF2α 的对映体，在尿液中可被发现。

16,16-dimethyl Prostaglandin A1 是一种前列腺素类似物，可以抑制 Lewis 肺癌和 B 16无黑色素瘤细胞中的 DNA 合成 (DNA synthesis)，以及抑制 HSV 和 HIV-1的病毒复制。

16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 μg ml. Daily infusion of 10 μg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.