mut

MUT056399 (Fab-001) 是一种金黄色葡萄球菌和大肠杆菌的 FabI 酶的高效抑制剂，IC50值分别为 12 nM 和 58 nM。

N36Mut(e,g) 是一种gp41的HIV融合肽抑制剂，通过破坏前发夹中间体中的N端螺旋同源三聚体卷曲螺旋并形成异源三聚体来发挥作用。

Mutant IDH1-IN-2是突变型异柠檬酸脱氢酶蛋白抑制剂, 在荧光生物化学检测中IC50为16.6 nM，LS-MS 生物化学检测中IC50为＜22 nM,。

Bismuth Subsalicylate (Bismuth subsalicylat) 是口服抗酸和止泻试剂。它能够抑制体内前列腺素合成，抑制胃和肠道黏膜炎症反应。它广泛用于研究腹泻疾病，如恶心、消化不良、腹泻等。

Mutated EGFR-IN-1 (Osimertinib analog) 是用于突变 EGFR 抑制剂设计的有用中间体，例如 L858R EGFR、Exon19 缺失激活突变体和 T790M 抗性突变体。

Triphenyl bismuth (NSC-465) 是一种添加剂，用于使生物医学树脂在 X 射线图像上可见，并可用作骨科骨水泥的不透射线剂。

Bismuth subgallate (Dermatol Puder) 是一种止血剂，可作用于凝血因子 XII ，促使凝血级联的激活，改善纤维蛋白凝块的早期形成。

Temuterkib (LY3214996) 是高效选择性的ERK1和ERK2抑制剂，IC50为 5 nM，具有潜在的抗肿瘤活性。

Mutant IDH1-IN-1 是 IDH1突变体的选择性抑制剂，能够作用于突变体 IDH1 R132C R132C (IC50:4 nM) ，IDH1 R132H R132H (IC50:42 nM) ，IDH1 R132H WT (IC50:80 nM) 和野生型 IDH1 (IC50:143 nM)。

EGFR mutant- in-1, A 5-methylpyrimidopyridone derivative are effective selective EGFRL858R T790M C797S mutant inhibitors with IC50 of 27.5 nM, which significantly weakened EGFRWT effect.

Mutant IDH1-IN-4 is an mutant Isocitrate dehydrogenase 1 (IDH 1) inhibitor.

Mutated EGFR-IN-2 is an inhibitor of mutant-selective EGFR.

Mutated EGFR-IN-3 is a ATP-competitive and highly selective allosteric dibenzodiazepinone EGFR(L858R T790M) and EGFR(L858R T790M C797S) inhibitor(IC50 of 12 nM and 13 nM, respectively. )

RAF mutant-IN-1 is an inhibitor of RAF kinase(IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D Y341D, B-RAFV600E and B-RAFWT, respectively).

Mutant IDH1 inhibitor 是一种突变型IDH1 R132H 的抑制剂，IC50<72 nM。

Pleuromutilin (Drosophilin B) 通过与细菌的 50S 核糖体亚基结合来抑制细菌蛋白质的合成。

Elatipepimut-S 属于抗肿瘤化合物类别。

Mutant IDH1-IN-3 (Compound 1) 是一种选择性变构抑制剂，专门抑制突变型异柠檬酸脱氢酶 1 (IDH1)，其对 R132HIDH1 的 IC50 为 13 nM。Mutant IDH1-IN-3 能够在细胞中抑制 D-2 羟基戊二酸 (2HG) 的生成，适用于肿瘤研究。

Bismuth(III) oxide is a common starting point for bismuth chemistry. It is usually obtained as a by-product of the smelting of copper and lead ores. Bismuth trioxide is commonly used as a replacement of red lead to produce the “Dragon's eggs” effect in fi

Mutant EGFR inhibitor 是选择性EGFR 突变体抑制剂，可抑制EGFRL858R、EGFRExon 19 deletion 和EGFRT790M。

Bismuth camphocarbonate is used for herpes zoster.

Lemuteporfin, also known DRM05, QLT-0074 , is a diester derivative of benzoporphyrin derivative, is a neutral, uncharged benzoporphyrin molecule having symmetrical diethylene glycol groups; this maintains its amphiphilic character. It differs from another

Nelipepimut-S, as an immunogenic peptide from the HER2 protein, is highly expressed in breast cancer.

Bismuth subcarbonate, also known as bismuth carbonate oxide, is a versatile semiconductor compound based on bismuth, commonly utilized for its antibacterial properties, as well as in various applications such as sensors, super capacitors, and photocatalysts. Additionally, bismuth subcarbonate serves as a protective agent against gastric acid erosion, particularly in the treatment of gastric ulcers[1][2].